Toshio Kushiro

Summary

Affiliation: Nihon University
Country: Japan

Publications

  1. ncbi request reprint Different effects on inhibition of cardiac hypertrophy in spontaneously hypertensive rats by monotherapy and combination therapy of adrenergic receptor antagonists and/or the angiotensin II type 1 receptor blocker under comparable blood pressure reduction
    Takae Asai
    Division of Cardiovascular Medicine, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Hypertens Res 28:79-87. 2005
  2. ncbi request reprint Alcohol produces imbalance of adrenal and neuronal sympathetic activity in patients with alcohol-induced neurocardiogenic syncope
    Naoyuki Takahashi
    Department of Cardiology, Surugadai Nihon University Hospital, Tokyo, Japan
    Circ J 72:979-85. 2008
  3. doi request reprint Blood pressure control status and effects of pravastatin on cardiovascular events occurrence in patients with dyslipidaemia
    T Kushiro
    Health Planning Center, Nihon University School of Medicine, Tokyo, Japan
    J Hum Hypertens 26:388-95. 2012
  4. ncbi request reprint Different effects of L-type and L+N-type calcium channel blockers on hamster cheek pouch venules
    Toshio Kushiro
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    J Cardiovasc Pharmacol 44:672-5. 2004
  5. ncbi request reprint Erectile dysfunction and its influence on quality of life in patients with essential hypertension
    Toshio Kushiro
    Department of Cardiology, Nihon University Surugadai Hospital, 1 8 13 Kandasurugadai Chiyoda ku, Tokyo 101 8309, Japan
    Am J Hypertens 18:427-30. 2005
  6. doi request reprint Blood pressure-lowering effects of angiotensin receptor antagonist monotherapy and in combination with other anti-hypertensive drugs in primary care settings in Japan
    Toshio Kushiro
    Nihon University Health Planning Center, Chiyoda ku, Tokyo, Japan
    Clin Exp Hypertens 31:127-41. 2009
  7. doi request reprint Influence of guidelines on physicians' assessment of blood pressure lowering effects and achievement rate of blood pressure target during transitional period of guidelines
    Toshio Kushiro
    Nihon University Health Planning Center, Chiyoda ku, Tokyo, Japan
    Clin Exp Hypertens 31:116-26. 2009
  8. ncbi request reprint Oxidative stress in the Dahl salt-sensitive hypertensive rat
    Toshio Kushiro
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Clin Exp Hypertens 27:9-15. 2005
  9. doi request reprint Pravastatin for cardiovascular event primary prevention in patients with mild-to-moderate hypertension in the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA) Study
    Toshio Kushiro
    Nihon University School of Medicine, Health Planning Center, 1 7 3, Kandasurugadai, Chiyoda ku, Tokyo, 101 0062 Japan
    Hypertension 53:135-41. 2009
  10. ncbi request reprint Aliskiren, a novel oral renin inhibitor, provides dose-dependent efficacy and placebo-like tolerability in Japanese patients with hypertension
    Toshio Kushiro
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Hypertens Res 29:997-1005. 2006

Collaborators

Detail Information

Publications58

  1. ncbi request reprint Different effects on inhibition of cardiac hypertrophy in spontaneously hypertensive rats by monotherapy and combination therapy of adrenergic receptor antagonists and/or the angiotensin II type 1 receptor blocker under comparable blood pressure reduction
    Takae Asai
    Division of Cardiovascular Medicine, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Hypertens Res 28:79-87. 2005
    ..05). In conclusion, the ARB had the strongest attenuating effect on the development of hypertensive cardiac hypertrophy, and the alpha1 and beta adrenergic receptor blockers were more effective in combination than as monotherapies in SHR...
  2. ncbi request reprint Alcohol produces imbalance of adrenal and neuronal sympathetic activity in patients with alcohol-induced neurocardiogenic syncope
    Naoyuki Takahashi
    Department of Cardiology, Surugadai Nihon University Hospital, Tokyo, Japan
    Circ J 72:979-85. 2008
    ..The mechanism of alcohol-induced syncope is unknown...
  3. doi request reprint Blood pressure control status and effects of pravastatin on cardiovascular events occurrence in patients with dyslipidaemia
    T Kushiro
    Health Planning Center, Nihon University School of Medicine, Tokyo, Japan
    J Hum Hypertens 26:388-95. 2012
    ..The 12-month mean BP is useful to avoid attenuation to determine the association between CVD and BP. Pravastatin prevented CVA/TIA, regardless of BP controlled...
  4. ncbi request reprint Different effects of L-type and L+N-type calcium channel blockers on hamster cheek pouch venules
    Toshio Kushiro
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    J Cardiovasc Pharmacol 44:672-5. 2004
    ....
  5. ncbi request reprint Erectile dysfunction and its influence on quality of life in patients with essential hypertension
    Toshio Kushiro
    Department of Cardiology, Nihon University Surugadai Hospital, 1 8 13 Kandasurugadai Chiyoda ku, Tokyo 101 8309, Japan
    Am J Hypertens 18:427-30. 2005
    ..These data suggest that the influence of ED on QOL is more serious than hypertension in middle age men...
  6. doi request reprint Blood pressure-lowering effects of angiotensin receptor antagonist monotherapy and in combination with other anti-hypertensive drugs in primary care settings in Japan
    Toshio Kushiro
    Nihon University Health Planning Center, Chiyoda ku, Tokyo, Japan
    Clin Exp Hypertens 31:127-41. 2009
    ..This study suggests that ARBs such as OLM-elicits BP-lowering efficacy as either a first- or second-line agent and its effects are minimally influenced by co-administered anti-hypertensives...
  7. doi request reprint Influence of guidelines on physicians' assessment of blood pressure lowering effects and achievement rate of blood pressure target during transitional period of guidelines
    Toshio Kushiro
    Nihon University Health Planning Center, Chiyoda ku, Tokyo, Japan
    Clin Exp Hypertens 31:116-26. 2009
    ..Our data suggest that guidelines at the time strongly influence the physicians' assessment and their treatment strategy for individual patients in daily clinical practice...
  8. ncbi request reprint Oxidative stress in the Dahl salt-sensitive hypertensive rat
    Toshio Kushiro
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Clin Exp Hypertens 27:9-15. 2005
    ..1 +/- 48.4 ng/24 hr in LS versus 322.8 +/- 46.7 ng/24 hr in HS, p < .05), and U-8-OHdG was correlated with SBP (r = 0.681) in Dahl-S rats. These results suggest oxygen radicals are involved in the pathogenesis of hypertension...
  9. doi request reprint Pravastatin for cardiovascular event primary prevention in patients with mild-to-moderate hypertension in the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA) Study
    Toshio Kushiro
    Nihon University School of Medicine, Health Planning Center, 1 7 3, Kandasurugadai, Chiyoda ku, Tokyo, 101 0062 Japan
    Hypertension 53:135-41. 2009
    ..Hence, in patients with hypertension with mildly elevated cholesterol levels, treatment with a statin is advisable to reduce the burden of cardiovascular disease...
  10. ncbi request reprint Aliskiren, a novel oral renin inhibitor, provides dose-dependent efficacy and placebo-like tolerability in Japanese patients with hypertension
    Toshio Kushiro
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Hypertens Res 29:997-1005. 2006
    ....
  11. doi request reprint Long-term safety, tolerability, and antihypertensive efficacy of aliskiren, an oral direct renin inhibitor, in Japanese patients with hypertension
    Toshio Kushiro
    Nihon University School of Medicine, Tokyo, Japan
    Hypertens Res 32:169-75. 2009
    ..The overall responder rate was 73.3% at the end point. In conclusion, this first long-term study in Japanese patients showed the safety and efficacy of aliskiren-based therapy in mild-to-moderate essential hypertension...
  12. ncbi request reprint Effect of pravastatin on malondialdehyde-modified low-density lipoprotein levels and coronary plaque regression as determined by three-dimensional intravascular ultrasound
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Am J Cardiol 96:1089-94. 2005
    ..In conclusion, these results suggest that the reduction in the MDA-LDL levels induced by pravastatin may serve as a novel marker of coronary atherosclerosis regression...
  13. doi request reprint Usefulness of pravastatin in primary prevention of cardiovascular events in women: analysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA study)
    Kyoichi Mizuno
    Department of Internal Medicine, Nippon Medical School, 1 1 5, Sendagi, Bunkyo ku, Tokyo, 113 8603, Japan
    Circulation 117:494-502. 2008
    ..We conducted an exploratory analysis of the effect of diet plus pravastatin therapy on the primary prevention of cardiovascular events in women with data from a large-scale primary prevention trial with pravastatin...
  14. doi request reprint Amlodipine suppressed cardiac gene expression of brain natriuretic peptide, transforming growth factor-β₁ and fibronectin mediated by aldosterone in male stroke-prone spontaneously hypertensive rats
    Shinsuke Harasawa
    Department of Cardiology, Nihon University Surugadai Hospital Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    J Pharm Pharmacol 62:1740-5. 2010
    ..We evaluated whether the calcium channel blocker confers cardiac protection through the renin-angiotensin-aldosterone system in male stroke-prone spontaneously hypertensive rats (SHR-SP)...
  15. ncbi request reprint The relationship between the effect of pravastatin and risk factors for coronary heart disease in Japanese patients with hypercholesterolemia
    Toshitsugu Ishikawa
    Occupational Health Department, Sony Corporation, Tokyo, Japan
    Circ J 72:1576-82. 2008
    ..The present analysis determined the risk factors for CHD in the MEGA Study, a large primary prevention trial with pravastatin in Japanese with hypercholesterolemia...
  16. ncbi request reprint Increasingly well-preserved left ventricular function in hospital survivors with acute myocardial infarction: effect of early and complete reperfusion strategy on left ventricular remodeling
    Shigemasa Tani
    Division of Cardiovascular Medicine, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 71:180-5. 2007
    ..Progress in reperfusion therapy for acute myocardial infarction (AMI) has greatly reduced acute phase mortality, but few data exist regarding the time trends in left ventricular (LV) remodeling in hospital survivors of AMI...
  17. ncbi request reprint Unexpected coronary vasospasm of a contralateral artery during balloon angioplasty
    Shigemasa Tani
    Department of Cardiology, Surugadai Nihon University Hospital, 1 8 13 Kandasurugadai, Chiyoda ku, Tokyo 101 8309, Japan
    Heart Vessels 20:82-4. 2005
    ..We experienced a rare case of shock with vasospasm of the right coronary artery in a patient following balloon angioplasty performed for stent restenosis of the left anterior descending artery...
  18. ncbi request reprint Predictive factors of TIMI-3 flow before percutaneous coronary intervention in facilitated percutaneous coronary intervention for acute myocardial infarction
    Ikuyoshi Watanabe
    Division of Cardiovascular Medicine, Surugadai Nihon University Hospital, Tokyo, Japan
    Int Heart J 47:29-35. 2006
    ..The WBC count and hemoglobin value on arrival at the emergency room and history of smoking were shown to be independent factors for acquisition of TIMI-3 flow before PCI in facilitated PCI...
  19. doi request reprint Early antihypertensive efficacy of olmesartan medoxomil
    Ikuo Saito
    Keio University Health Center, Tokyo, Japan
    J Clin Hypertens (Greenwich) 10:930-5. 2008
    ..3% at 2 weeks in the standard BP determination group (P=NS). Rates of adverse drug reactions in the 2 groups were similar. The present study suggests that OM is safe and effective in reducing BP at an early time point of treatment...
  20. ncbi request reprint Pure ventricular septal myocardial infarction in a young man with coronary artery ectasia
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Int Heart J 47:131-7. 2006
    ....
  21. ncbi request reprint Use of bepridil in combination with Ic antiarrhythmic agent in converting persistent atrial fibrillation to sinus rhythm
    Shinobu Imai
    Department of Cardiology, Nihon University Surugadai Hospital, Nihon University School of Medicine, Tokyo, Japan
    Circ J 72:709-15. 2008
    ..The conversion effect of bepridil alone is not always satisfactory, however. The efficacy of pharmacological cardioversion by the combination of bepridil and a class Ic antiarrhythmic drug for persistent AF is studied...
  22. ncbi request reprint Renoprotective effect and cost-effectiveness of using benidipine, a calcium channel blocker, to lower the dose of angiotensin receptor blocker in hypertensive patients with albuminuria
    Fumio Saito
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Hypertens Res 30:39-47. 2007
    ....
  23. ncbi request reprint Effect of morning and bedtime dosing with cilnidipine on blood pressure, heart rate, and sympathetic nervous activity in essential hypertensive patients
    Yasuyuki Kitahara
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    J Cardiovasc Pharmacol 43:68-73. 2004
    ....
  24. ncbi request reprint Basic autonomic nervous function in patients with neurocardiogenic syncope
    Fumio Saito
    Department of Cardiology, Surugadai Nihon University Hospital, Tokyo, Japan
    Clin Exp Hypertens 29:165-73. 2007
    ....
  25. ncbi request reprint Relationship between the generation and the facilitated percutaneous coronary intervention in patients with acute myocardial infarction--analysis based on the fibrinolysis and subsequent transluminal trial--
    Ikuyoshi Watanabe
    Division of Cardiovascular Medicine, Surugadai Nihon University Hospital, Chiyoda ku, Tokyo, Japan
    Circ J 68:1117-22. 2004
    ..The purpose of the present study was to evaluate the efficacy and safety of facilitated percutaneous coronary intervention (PCI) in comparing young and elderly patients with acute myocardial infarction...
  26. ncbi request reprint Relationship between the plasma levels of brain natriuretic peptide and left ventricular ejection fraction in asymptomatic patients with previous myocardial infarction
    Ikuyoshi Watanabe
    Division of Cardiovascular Medicine, Surugadai Nihon University Hospital, Tokyo, Japan
    Int Heart J 46:1007-14. 2005
    ..8% for a plasma BNP cut-off level of 89.0 pg/mL. The results suggested that it might be meaningful to measure the plasma BNP level, especially in asymptomatic patients with a previous history of myocardial infarction having a low-EF...
  27. ncbi request reprint Regulation of arginine vasopressin in the human heart
    Ikuyoshi Watanabe
    Division of Cardiovascular Medicine, Surugadai Nihon University Hospital, Tokyo, Japan
    Circ J 69:1401-4. 2005
    ..The role of arginine vasopressin (AVP) in the heart has yet to be determined. The present study was designed to examine whether AVP is regulated in the human heart...
  28. ncbi request reprint Efficacy of calcium channel blocker in the secondary prevention of myocardial infarction--retrospective analysis of the 10-year prognosis or coronary thrombolysis-treated patients
    Shigemasa Tani
    Division of Cardiology, Department of Internal Medicine, Nihon University School of Medicine and Surugadai Nihon University Hospital, Chiyoda ku, Tokyo, Japan
    Circ J 68:853-9. 2004
    ..Calcium channel blockers (CCBs) may have a positive influence on the long-term prognosis of Japanese patients with ischemic heart disease...
  29. ncbi request reprint Clinical and electrophysiological characteristics of binodal disease
    Yoshitaka Sakai
    Department of Cardiology, Nihon University School of Medicine, Tokyo, Japan
    Circ J 70:1580-4. 2006
    ....
  30. ncbi request reprint Safety and efficacy of sirolimus-eluting stent in patients with acute coronary syndrome undergoing emergency procedure
    Kazumiki Nomoto
    Department of Cardiology, Kawaguchi Municipal Medical Center, 180 Nishi araijuku, Kawaguchi 333 0833, Japan
    Circ J 72:1054-8. 2008
    ..This study investigated the safety and efficacy of SES for emergency PCI in acute coronary syndrome (ACS) patients...
  31. ncbi request reprint Insulin sensitivity and endothelial function in hypertension: a comparison of temocapril and candesartan
    Hirofumi Tomiyama
    Second Department of Internal Medicine, Tokyo Medical University, Tokyo, Japan
    Am J Hypertens 18:178-82. 2005
    ..The present study compared the effects of ACEi and ARB on END and IS in patients with hypertension...
  32. ncbi request reprint Mismatch between results of myocardial fractional flow reserve (FFR) measurements and myocardial perfusion SPECT for identification of the severity of ischemia: pitfall of FFR in patients with prior myocardial infarction
    Shigemasa Tani
    Department of Cardiology, Surugadai Nihon University Hospital, Tokyo 101 8309, Japan
    Jpn Heart J 45:867-72. 2004
    ..If a FFR cutoff value of 0.75 is applied as in angina patients to patients with myocardial infarction, the severity of ischemia may be underestimated...
  33. ncbi request reprint Tempol attenuates the development of hypertensive renal injury in Dahl salt-sensitive rats
    Ryohei Hisaki
    Division of Cardiovascular Medicine, Surugadai Nihon University Hospital, Tokyo, Japan
    Am J Hypertens 18:707-13. 2005
    ..This study looks at the effects of a superoxide scavenger in preventing of hypertensive renal damage in high-salt-treated DS rats...
  34. ncbi request reprint Effect of pioglitazone on arteriosclerosis in comparison with that of glibenclamide
    Ikuyoshi Watanabe
    Department of Cardiology, Surugadai Nihon University Hospital, 1 8 13, Kandasurugadai, Chiyoda ku, Tokyo, 101 0062 Japan
    Diabetes Res Clin Pract 68:104-10. 2005
    ..Pioglitazone is an insulin-sensitizing agent that has been reported to have anti-arteriosclerotic effects...
  35. ncbi request reprint Role of the low amplitude potential in the initial P wave signal-averaged electrocardiogram [corrected] in sick sinus syndrome
    Hidehito Takase
    Division of Cardiovascular Medicine, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 70:985-90. 2006
    ..The cause of abnormally low amplitude of the initial P wave signal-averaged electrocardiogram (P-SAECG) in patients with sick sinus syndrome (SSS) is unknown...
  36. ncbi request reprint Involvement of inflammation in acute coronary syndromes assessed by levels of high-sensitivity C-reactive protein, matrix metalloproteinase-9 and soluble vascular-cell adhesion molecule-1
    Kazumiki Nomoto
    Department of Cardiology, Nihon University Surugadai Hospital, Kanda Surugadai 1 8 13, Chiyoda ku, Tokyo 101 8309
    J Cardiol 42:201-6. 2003
    ..This study investigated whether inflammation is related to the onset of acute coronary syndrome...
  37. ncbi request reprint Diagnostic value of adenosine-induced left ventricular diastolic dysfunction for detecting coronary artery restenosis in patients undergoing stent implantation by Stress ECG-gated myocardial perfusion SPECT. A pilot study
    Yoshimochi Nakano
    Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 74:2658-65. 2010
    ....
  38. ncbi request reprint Efficacy of low-density lipoprotein apheresis in arteriosclerosis obliterans of the lower extremities: two cases with marked alleviation of clinical symptoms
    Toshihide Suzuki
    Department of Cardiology, Surugadai Nihon University Hospital, Tokyo, Japan
    J Clin Apher 22:287-91. 2007
    ..Our findings suggest that LDL-A combined with drug treatment is safe and useful for the treatment of ASO, especially walking distance improved with short term treatment...
  39. ncbi request reprint Takotsubo-shaped cardiomyopathy with type I CD36 deficiency
    Toshio Kushiro
    Department of Cardiology, Nihon University Hospital, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo, 101 8309, Japan
    Heart Vessels 20:123-5. 2005
    ..Further studies of Takotsubo-shaped cardiomyopathy and CD36 deficiency may reveal an association between this cardiomyopathy and specific genetic profiles...
  40. ncbi request reprint [Pioglitazone effects on blood pressure in patients with metabolic syndrome]
    Atsuhiko Takahashi
    Nihon University Health Planning Center, Nihon University School of Medicine
    Nihon Rinsho 66:1591-5. 2008
    ..Pioglitazone has favorable effects on important components of metabolic syndrome including blood pressure...
  41. ncbi request reprint Reperfusion strategy for acute myocardial infarction in elderly patients aged 75 to 80 years
    Ikuyoshi Watanabe
    Division of Cardiovascular Medicine, Surugadai Nihon University Hospital, 1 8 13 Kandasurugadai, Tokyo 101 0062, Japan
    Heart Vessels 21:236-41. 2006
    ..Considering reperfusion therapy in elderly patients with acute myocardial infarction, we concluded that facilitated PCI may be effective in elderly patients aged 75-80 years...
  42. doi request reprint A pilot trial to predict frailty syndrome: the Japanese Health Research Volunteer Study
    Nobutaka Doba
    Division of Research and Education, Life Planning Center Foundation, Sasakawa Kinen Kaikan, Eleventh Floor, 12 12, Mita 3 chome, Minato ku, Tokyo, 108 0073, Japan
    Exp Gerontol 47:638-43. 2012
    ..While further study is needed, this work creates an easy-to-administer tool that may be generalizable to other populations...
  43. ncbi request reprint [Current status of blood pressure control in Japan and strategies for the better control]
    Atsuhiko Takahashi
    Nihon University Health Planning Center, Nihon University School of Medicine
    Nihon Rinsho 69:1969-76. 2011
    ..First step to improve the blood pressure control status is identifying reasons. To solve the identified problems, comprehensive approaches by health professionals are necessary...
  44. ncbi request reprint Relationship between heart-type fatty acid-binding protein levels and the risk of death in patients with serious condition on arrival at the emergency department
    Kiyoshi Iida
    Department of Cardiology, Nihon University School of Medicine, Tokyo
    Intern Med 44:1039-45. 2005
    ..The objective of this study is to clarify the prognostic value of H-FABP in patients with a serious condition...
  45. ncbi request reprint Does high-power computed tomography scanning equipment affect the operation of pacemakers?
    Satoshi Yamaji
    Division of Cardiovascular Medicine, Department of Medicine, Nihon University School of Medicine, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo 101 8309, Japan
    Circ J 70:190-7. 2006
    ..Computed tomography (CT) is widely used in clinical practice, but there has not been a detailed report of its effect on the functioning of pacemakers...
  46. ncbi request reprint Oral peppermint oil is a useful antispasmodic for double-contrast barium meal examination
    Shigeaki Mizuno
    Department of Gastroenterology and Hepatology, Nihon University School of Medicine, Tokyo, Japan
    J Gastroenterol Hepatol 21:1297-301. 2006
    ..The aim of this study was to examine the efficacy of oral PO for double-contrast barium meal examination (DCBM) without other antispasmodics...
  47. ncbi request reprint Effect of pravastatin on coronary plaque volume
    Kazutoshi Ishikawa
    Department of Cardiology, Surugadai Nihon University Hospital, Tokyo, Japan
    Am J Cardiol 92:975-7. 2003
    ..The changes in plaque volume were inversely correlated with the changes in plasma levels of high-density lipoprotein cholesterol but not with changes in levels of total cholesterol or low-density lipoprotein cholesterol...
  48. ncbi request reprint Influences of increased oxidative stress on endothelial function, platelets function, and fibrinolysis in hypertension associated with glucose intolerance
    Hirofumi Tomiyama
    Second Department of Internal Medicine, Tokyo Medical University, Tokyo, Japan
    Hypertens Res 26:295-300. 2003
    ..In conclusion, glucose intolerance aggravates oxidative stress, thereby contributing to the impairment of endothelial function in patients with hypertension. These abnormalities affect fibrinolysis but not platelet function...
  49. ncbi request reprint [Therapy for hypertension associated with diabetes mellitus]
    Toshio Kushiro
    Nihon Naika Gakkai Zasshi 92:243-9. 2003
  50. ncbi request reprint [Intervention studies on elderly hypertensive patients in Japan]
    Fumio Saito
    Department of Cardiology, Surugadai Nihon University Hospital
    Nihon Rinsho 63:1078-85. 2005
    ..We summarize the content of intervention studies on elderly hypertensive patients in western countries and Japan...
  51. doi request reprint Impact of blood pressure control on cardiovascular events in 26,512 Japanese hypertensive patients: the Japan Hypertension Evaluation with Angiotensin II Antagonist Losartan Therapy (J-HEALTH) study, a prospective nationwide observational study
    Kazuaki Shimamoto
    Sapporo Medical University School of Medicine, Sapporo, Japan
    Hypertens Res 31:469-78. 2008
    ..BP was controlled below 140/90 mmHg in a half of the very elderly hypertensive patients in this study, and these patients also had a lower incidence of CV events...
  52. ncbi request reprint [Treatment of elderly hypertension with Ca channel blockers]
    Fumio Saito
    Department of Cardiology, Surugadai Nihon University Hospital
    Clin Calcium 15:1717-25. 2005
    ..We summarize the results of the studies using CCB in elderly hypertensive patients and the therapeutic strategy using CCB in elderly hypertensive patients...
  53. ncbi request reprint Class of antihypertensive drugs, blood pressure status, and risk of cardiovascular disease in hypertensive patients: a case-control study in Japan
    Suminori Kono
    Department of Preventive Medicine, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hypertens Res 28:811-7. 2005
    ..The findings suggest that appropriate control of blood pressure is more important in the treatment of hypertension than the choice of antihypertensives...
  54. ncbi request reprint The use of olmesartan medoxomil as monotherapy or in combination with other antihypertensive agents in elderly hypertensive patients in Japan
    Ikuo Saito
    Health Center, Keio University, Yokohama, Kanagawa, Japan
    J Clin Hypertens (Greenwich) 10:272-9. 2008
    ..Treatment was well tolerated in all groups. In conclusion, the medication was safe and effective in reducing BP levels in ISH patients aged 75 years and older, as well as in other elderly hypertensive patients...
  55. ncbi request reprint Expression of matrix Gla protein and osteonectin mRNA by human aortic smooth muscle cells
    Hiroyuki Hao
    Department of Pathology, National Cardiovascular Center, Suita, Osaka, Japan
    Cardiovasc Pathol 13:195-202. 2004
    ..Recent data indicate that matrix proteins such as matrix Gla protein (MGP) and osteonectin (ON) influence not only mineralization of vasculature but smooth muscle cell (SMC) differentiation...
  56. ncbi request reprint A case of vasospastic angina showing resolution of coronary vasospasm in acetylcholine provocation test corresponding to regression of coronary atherosclerosis
    Shigemasa Tani
    Int J Cardiol 125:e1-3. 2008
    ....
  57. ncbi request reprint [Pathogenesis and etiology of cardiovascular disease: role of insulin resistance]
    Atsuhiko Takahashi
    Nihon University Health Planning Center
    Nihon Rinsho 64:163-8. 2006
  58. ncbi request reprint [Drug-induced dyslipidemia]
    Katsuaki Okubo
    Department of Cardiology, Surugadai Hospital of Nihon University
    Nihon Rinsho 65:426-8. 2007