H Kushi

Summary

Affiliation: Nihon University
Country: Japan

Publications

  1. ncbi request reprint Neuronal damage in pericontusional edema zone
    H Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Acta Neurochir Suppl 86:339-42. 2003
  2. doi request reprint Acute subdural hematoma because of boxing
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Itabashi ku, Tokyo, Japan
    J Trauma 66:298-303. 2009
  3. doi request reprint Criteria for direct hemoperfusion with an immobilized polymyxin B fiber column based on oxygen metabolism
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Ther Apher Dial 12:292-7. 2008
  4. doi request reprint Early hemoperfusion with a polymyxin b column improves gastric intramucosal pH in sepsis
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Ther Apher Dial 12:278-84. 2008
  5. ncbi request reprint Hemoperfusion with an immobilized polymyxin B fiber column improves tissue oxygen metabolism
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Ther Apher Dial 10:430-5. 2006
  6. ncbi request reprint Hemoperfusion with an immobilized polymyxin B fiber column reduces circulating interleukin-8 concentrations
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Ther Apher Dial 10:425-9. 2006
  7. ncbi request reprint Hemoperfusion with an immobilized polymyxin B column reduces the blood level of neutrophil elastase
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Blood Purif 24:212-7. 2006
  8. pmc Early hemoperfusion with an immobilized polymyxin B fiber column eliminates humoral mediators and improves pulmonary oxygenation
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, 30 1 Oyaguchi Kamimachi, Tokyo, 173 8610, Japan
    Crit Care 9:R653-61. 2005
  9. ncbi request reprint Hemoperfusion with an immobilized polymyxin B fiber column inhibits activation of vascular endothelial cells
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Ther Apher Dial 9:303-7. 2005
  10. ncbi request reprint IL-8 is a key mediator of neuroinflammation in severe traumatic brain injuries
    H Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Acta Neurochir Suppl 86:347-50. 2003

Detail Information

Publications14

  1. ncbi request reprint Neuronal damage in pericontusional edema zone
    H Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Acta Neurochir Suppl 86:339-42. 2003
    ..The PEZ is thought to be due to microvascular disturbance by neutrophils stimulated by inflammatory cytokines, and neuronal damage from migrated neutrophils...
  2. doi request reprint Acute subdural hematoma because of boxing
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Itabashi ku, Tokyo, Japan
    J Trauma 66:298-303. 2009
    ..To identify factors determining the clinical characteristics and prognosis of acute subdural hematoma (ASDH) arising from boxing injuries by comparing with ASDH due to any nonboxing cause...
  3. doi request reprint Criteria for direct hemoperfusion with an immobilized polymyxin B fiber column based on oxygen metabolism
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Ther Apher Dial 12:292-7. 2008
    ..Based on these results, DHP-PMX should be introduced during the period when VO(2)I is still equal to or greater than 100 mL/min/m(2)...
  4. doi request reprint Early hemoperfusion with a polymyxin b column improves gastric intramucosal pH in sepsis
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Ther Apher Dial 12:278-84. 2008
    ..Because this was a prospective uncontrolled observational study on a limited number of patients, larger multicenter clinical trials are required to more accurately assess the benefits of DHP-PMX...
  5. ncbi request reprint Hemoperfusion with an immobilized polymyxin B fiber column improves tissue oxygen metabolism
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Ther Apher Dial 10:430-5. 2006
    ..8 mm Hg (P = 0.046) at 48 h, and 11 +/- 2.2 mm Hg (P = 0.045) at 72 h afterward, showing a significant decrease from 48 h onward compared with before treatment. These findings suggest that DHP-PMX improves tissue oxygen metabolism...
  6. ncbi request reprint Hemoperfusion with an immobilized polymyxin B fiber column reduces circulating interleukin-8 concentrations
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Ther Apher Dial 10:425-9. 2006
    ..0 +/- 0.9 at 72 h afterward, showing a significant decrease compared with before treatment (P < 0.05). The present findings indicate that DHP-PMX indirectly reduces circulating interleukin-8 concentration and improves SOFA score...
  7. ncbi request reprint Hemoperfusion with an immobilized polymyxin B column reduces the blood level of neutrophil elastase
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Blood Purif 24:212-7. 2006
    ..We investigated whether direct hemoperfusion with an immobilized polymyxin B column (DHP with PMX) could reduce the blood level of neutrophil elastase...
  8. pmc Early hemoperfusion with an immobilized polymyxin B fiber column eliminates humoral mediators and improves pulmonary oxygenation
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, 30 1 Oyaguchi Kamimachi, Tokyo, 173 8610, Japan
    Crit Care 9:R653-61. 2005
    ....
  9. ncbi request reprint Hemoperfusion with an immobilized polymyxin B fiber column inhibits activation of vascular endothelial cells
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Ther Apher Dial 9:303-7. 2005
    ..0 ng/mL at 48 h after, and 64+/-18.3 ng/mL 72 h after. The values were significantly lower from 48 h onward compared with baseline. These data suggest that DHP with PMX inhibits vascular endothelial cell activation...
  10. ncbi request reprint IL-8 is a key mediator of neuroinflammation in severe traumatic brain injuries
    H Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Acta Neurochir Suppl 86:347-50. 2003
    ..The fact that CSF IL-8 was 1000 times that in the peripheral blood at the time of admission, and decreased thereafter, indicates that IL-8 is a key mediator of neuroinflammation...
  11. doi request reprint Hemoperfusion with a polymyxin B fiber column decreases clotting activity
    Hidehiko Kushi
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Surugadai, Chiyoda ku, Tokyo 101 8306, Japan
    Ther Apher Dial 13:528-33. 2009
    ..This coagulation/fibrinolysis imbalance was improved by DHP-PMX. The present results suggest that indirect inhibition of clotting activity can be achieved in patients with sepsis through adsorption of lipopolysaccharide by DHP-PMX...
  12. ncbi request reprint The risk factors for the occurrence of acute brain swelling in acute subdural hematoma
    T Saito
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Acta Neurochir Suppl 86:351-4. 2003
    ..Conspicuous hypertension before the surgery was shown to be a possible risk factor for ABS. Therefore; MAP > or = 140 mmHg may be a warning sign for the occurrence of ABS...
  13. ncbi request reprint Characteristics of parietal-parasagittal hemorrhage after mild or moderate traumatic brain injury
    K Kinoshita
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, Tokyo, Japan
    Acta Neurochir Suppl 86:343-6. 2003
    ..The patients with parietal-parasagittal TICH were clinically analyzed based on the initial brain CT findings, hematoma sites and the clinical course as compared to those with TICH at other sites...
  14. ncbi request reprint Risk factors for intraoperative hypotension in traumatic intracranial hematoma
    Kosaku Kinoshita
    Department of Emergency and Critical Care Medicine, Nihon University School of Medicine, 30 1, Oyaguchi Kamimachi, Itabashi ku, Tokyo 173 8610, Japan
    Resuscitation 60:151-5. 2004
    ..We concluded that an important factor in the occurrence of IHT was not only the injury severity, but also the balance between sympathetic and parasympathetic activity before decompression surgery...