Susumu Kitanaka

Summary

Affiliation: Nihon University
Country: Japan

Publications

  1. doi request reprint Inhibitory effect of chemical constituents from Artemisia scoparia Waldst. et Kit. on triglyceride accumulation in 3T3-L1 cells and nitric oxide production in RAW 264.7 cells
    Tadahiro Yahagi
    School of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba, 274 8555, Japan
    J Nat Med 68:414-20. 2014
  2. pmc New benzophenone and quercetin galloyl glycosides from Psidium guajava L
    Keiichi Matsuzaki
    Research Unit of Pharmacognosy, College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    J Nat Med 64:252-6. 2010
  3. ncbi request reprint Lignans from the roots of Wikstroemia indica and their DPPH radical scavenging and nitric oxide inhibitory activities
    Li Yan Wang
    Department of Pharmacognosy, College of Pharmacy, Nihon University, Funabashi, Chiba, Japan
    Chem Pharm Bull (Tokyo) 53:1348-51. 2005
  4. ncbi request reprint Sesquiterpene phenylpropanoids from Ferula fukanensis and their nitric oxide production inhibitory effects
    Tsunetake Motai
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    J Nat Prod 68:365-8. 2005
  5. doi request reprint Analysis of inhibition of topoisomerase IIalpha and cancer cell proliferation by ingenolEZ
    Chisato Yoshida
    Department of Chemistry, College of Humanities and Sciences, Nihon University, Tokyo, Japan
    Cancer Sci 101:374-8. 2010
  6. doi request reprint Kadsuracoccinic acids A-C, ring-A seco-lanostane triterpenes from Kadsura coccinea and their effects on embryonic cell division of Xenopus laevis
    Heran Li
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    J Nat Prod 71:739-41. 2008
  7. ncbi request reprint Sesquiterpene chromones from Ferula fukanensis and their nitric oxide production inhibitory effects
    Tsunetake Motai
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    J Nat Prod 68:1732-5. 2005
  8. ncbi request reprint Sesquiterpene coumarins from Ferula fukanensis and nitric oxide production inhibitory effects
    Tsunetake Motai
    College of Pharmacy, Nihon University, Chiba, Japan
    Chem Pharm Bull (Tokyo) 52:1215-8. 2004
  9. doi request reprint Tetracyclic chromane derivatives from Rhododendron anthopogonoides
    Naoki Iwata
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba, Japan
    J Nat Prod 73:1203-6. 2010
  10. ncbi request reprint New phenanthrenes and stilbenes from Dendrobium loddigesii
    Masanobu Ito
    Research Unit of Pharmacognosy, School of Pharmacy, Nihon University, 7 7 1 Narasinodai, Funabashi, Chiba 274 8555, Japan
    Chem Pharm Bull (Tokyo) 58:628-33. 2010

Collaborators

Detail Information

Publications34

  1. doi request reprint Inhibitory effect of chemical constituents from Artemisia scoparia Waldst. et Kit. on triglyceride accumulation in 3T3-L1 cells and nitric oxide production in RAW 264.7 cells
    Tadahiro Yahagi
    School of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba, 274 8555, Japan
    J Nat Med 68:414-20. 2014
    ..7). These results indicate that the 80 % aqueous EtOH extract and compounds isolated from the aerial part of A. scoparia Waldst. et Kit. may improve obesity-related insulin resistance...
  2. pmc New benzophenone and quercetin galloyl glycosides from Psidium guajava L
    Keiichi Matsuzaki
    Research Unit of Pharmacognosy, College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    J Nat Med 64:252-6. 2010
    ..Isolated phenolic glycosides showed significant inhibitory activities against histamine release from rat peritoneal mast cells, and nitric oxide production from a murine macrophage-like cell line, RAW 264.7...
  3. ncbi request reprint Lignans from the roots of Wikstroemia indica and their DPPH radical scavenging and nitric oxide inhibitory activities
    Li Yan Wang
    Department of Pharmacognosy, College of Pharmacy, Nihon University, Funabashi, Chiba, Japan
    Chem Pharm Bull (Tokyo) 53:1348-51. 2005
    ..6 and 53.5 microM, respectively. Compound 5 also showed free radical scavenging effect on 1,1-diphenyl-2-picrylhydrazil (DPPH) at IC50 values at 19.5 microM...
  4. ncbi request reprint Sesquiterpene phenylpropanoids from Ferula fukanensis and their nitric oxide production inhibitory effects
    Tsunetake Motai
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    J Nat Prod 68:365-8. 2005
    ..7), which was activated by lipopolysaccharide (LPS) and recombinant mouse interferon-gamma (IFN-gamma)...
  5. doi request reprint Analysis of inhibition of topoisomerase IIalpha and cancer cell proliferation by ingenolEZ
    Chisato Yoshida
    Department of Chemistry, College of Humanities and Sciences, Nihon University, Tokyo, Japan
    Cancer Sci 101:374-8. 2010
    ..20-O-ingenolEZ inhibited topoisomerase IIalpha activity through inhibition of ATPase, and induced DNA-decatenation checkpoint without signaling for phosphorylation of H2AX...
  6. doi request reprint Kadsuracoccinic acids A-C, ring-A seco-lanostane triterpenes from Kadsura coccinea and their effects on embryonic cell division of Xenopus laevis
    Heran Li
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    J Nat Prod 71:739-41. 2008
    ..Treatment of cultured individual Xenopus laevis cells with 1 at the blastular stage arrested cleavage of these cells with an IC 50 of 0.32 microg/mL...
  7. ncbi request reprint Sesquiterpene chromones from Ferula fukanensis and their nitric oxide production inhibitory effects
    Tsunetake Motai
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    J Nat Prod 68:1732-5. 2005
    ..7), which was activated by lipopolysaccharide (LPS) and recombinant mouse interferon-gamma (IFN-gamma)...
  8. ncbi request reprint Sesquiterpene coumarins from Ferula fukanensis and nitric oxide production inhibitory effects
    Tsunetake Motai
    College of Pharmacy, Nihon University, Chiba, Japan
    Chem Pharm Bull (Tokyo) 52:1215-8. 2004
    ..7), which was activated by lipopolysaccharide (LPS) and recombinant mouse interferon-gamma (IFN-gamma)...
  9. doi request reprint Tetracyclic chromane derivatives from Rhododendron anthopogonoides
    Naoki Iwata
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba, Japan
    J Nat Prod 73:1203-6. 2010
    ..Compounds 1 and 2 inhibited compound 48/80-induced histamine release from rat peritoneal mast cells...
  10. ncbi request reprint New phenanthrenes and stilbenes from Dendrobium loddigesii
    Masanobu Ito
    Research Unit of Pharmacognosy, School of Pharmacy, Nihon University, 7 7 1 Narasinodai, Funabashi, Chiba 274 8555, Japan
    Chem Pharm Bull (Tokyo) 58:628-33. 2010
    ..One new dihydrostilbene, loddigesiinol D (9), showed weak inhibitory activity against NO production with an IC(50) value of 69.7 microM, but the other new dihydrostilbene, loddigesiinol C (8), did not show this activity at 100 microM...
  11. ncbi request reprint Kadsuralignans H-K from Kadsura coccinea and their nitric oxide production inhibitory effects
    Heran Li
    College of Pharmacy, Nihon University, Funabashi, Chiba, Japan
    J Nat Prod 70:1999-2002. 2007
    ..Compounds 1 and 3 showed inhibitory activity on nitric oxide (NO) production by the murine macrophage-like cell RAW264.7, which was activated by lipopolysaccharide (LPS) and recombinant mouse interferon-gamma (INF-gamma)...
  12. ncbi request reprint Stilbene derivatives from Pholidota chinensis and their anti-inflammatory activity
    Jue Wang
    Department of Pharmacognosy, College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, China
    Chem Pharm Bull (Tokyo) 54:1216-8. 2006
    ..Pholidotols A both B and inhibited Nitric oxide (NO) production with an IC(50) value at 24.3 and 17.1 microM, respectively...
  13. ncbi request reprint Inhibition of cellular proliferation by diterpenes, topoisomerase II inhibitor
    Shohei Miyata
    Department of Chemistry, College of Humanities and Sciences, Nihon University, Sakurajosui, Tokyo 156 8550, Japan
    Bioorg Med Chem 14:2048-51. 2006
    ..Most of the diterpene compounds that inhibited cellular proliferation also inhibited topoisomerase II activity...
  14. ncbi request reprint Antiallergic agents from natural sources 9. Inhibition of nitric oxide production by novel chalcone derivatives from Mallotus philippinensis (Euphorbiaceae)
    Akihiro Daikonya
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    Chem Pharm Bull (Tokyo) 52:1326-9. 2004
    ..Furthermore, they downregulated cyclooxygenase-2 (COX-2) gene, interleukin-6 (IL-6) gene and interleukin-1beta (IL-1beta) gene expression. These results suggest that they have anti-inflammatory and immunoregulatory effects...
  15. doi request reprint Inhibitory effects of constituents from Morus alba var. multicaulis on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells
    Zhi Gang Yang
    School of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    Molecules 16:6010-22. 2011
    ..The arylbenzofurans 1-10 and prenyl-flavonoids 11-16 also showed significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells...
  16. doi request reprint Anti-tumor promoters phenolics and triterpenoid from Hippophae rhamnoides
    Ken Yasukawa
    College of Pharmacy, Nihon University, Chiba 274 8555, Japan
    Fitoterapia 80:164-7. 2009
    ..Within the tested compounds, 3 and 4 showed marked anti-inflammatory effects, with a 50% inhibitory dose of 1.7 and 0.2 mumol/ear...
  17. ncbi request reprint Structures and histamine release inhibitory effects of prenylated orcinol derivatives from Rhododendron dauricum
    Naoki Iwata
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    J Nat Prod 67:1106-9. 2004
    ..Compounds 1-6 significantly inhibited compound 48/80-induced histamine release from rat peritoneal mast cells...
  18. ncbi request reprint Sesquiterpene coumarins from Ferula fukanensis and nitric oxide production inhibitory effects
    Tsunetake Motai
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    J Nat Prod 67:432-6. 2004
    ..7), which was activated by lipopolysaccharide (LPS) and recombinant mouse interferon-gamma (IFN-gamma)...
  19. ncbi request reprint Anti-inflammatory activity of new guaiane type sesquiterpene from Wikstroemia indica
    Li Yan Wang
    Department of Pharmacognosy, College of Pharmacy, Nihon University, Chiba, Japan
    Chem Pharm Bull (Tokyo) 53:137-9. 2005
    ..This is the first report of NO production inhibitory activity of Wikstroemia indica and supports the pharmacological use of it, which has been employed as an herbal medicine for the treatment of inflammation...
  20. ncbi request reprint New feruloyl tyramine glycosides from Stephania hispidula YAMAMOTO
    Tadahiro Yahagi
    College of Pharmacy, Nihon University, Chiba 274 8555, Japan
    Chem Pharm Bull (Tokyo) 58:415-7. 2010
    ..The structures were elucidated by spectroscopic and chemical analysis...
  21. ncbi request reprint Polyacetylenes in hairy roots of a panax hybrid
    Daisuke Washida
    College of Pharmacy, Nihon University, Narashinodai, Funabashi shi, Chiba, Japan
    Planta Med 69:1163-5. 2003
    ..24 mmol/flask polyacetylenes and 4.45 mmol/flask ginsenosides at week 8)...
  22. ncbi request reprint Determination of polyacetylenes and ginsenosides in Panax species using high performance liquid chromatography
    Daisuke Washida
    College of Pharmacy, Nihon University, Chiba 274 8555, Japan
    Chem Pharm Bull (Tokyo) 51:1314-7. 2003
    ..The species containing the highest polyacetylene content (0.080%) was P. quinquefolium cultivated in Nagano, Japan. Meanwhile, the species with the highest ginsenoside content (9.176%) was P. noteginseng cultivated in Yunnan, China...
  23. ncbi request reprint Inhibitory effect of stevioside on tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin
    Ken Yasukawa
    College of Pharmacy, Nihon University, Chiba, Japan
    Biol Pharm Bull 25:1488-90. 2002
    ..0 and 0.1 mg/mouse of stevioside mixture, the mixture of these compounds markedly inhibited the promoting effect of TPA (1 micro g/mouse) on skin tumor formation initiated with 7,12-dimethylbenz[a]anthracene (50 micro g/mouse)...
  24. ncbi request reprint Selective inhibition of the growth of cancer cells by diterpenes selected with embryonic cells of Xenopus
    Shohei Miyata
    Department of Chemistry, College of Humanities and Sciences, Nihon University, Sakurajosui, Setagaya Ku, Tokyo 156 8550, Japan
    Cell Biol Int 28:179-84. 2004
    ..The inhibitory compounds selected using the embryonic cells also inhibited proliferation of certain mammalian cell types...
  25. ncbi request reprint New small-scale cross-axis coil planet centrifuge. Partition efficiency and application to purification of bullfrog ribonuclease
    Kazufusa Shinomiya
    College of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi shi, Chiba 274 8555, Japan
    J Chromatogr A 1151:91-8. 2007
    ..The cSBL retained its native RNase activity. The overall results demonstrated that the present new small-scale X-axis CPC is useful for the purification of bioactive compounds without loss of their native activities...
  26. doi request reprint Biotransformation of zerumbone by Caragana chamlagu
    Hiroshi Sakamaki
    College of Science and Technology, Nihon University, 7 24 1 Narashinodai, Funabashi shi, Chiba, 274 8501, Japan
    Biotechnol Lett 30:2025-9. 2008
    ....
  27. ncbi request reprint Identification of dendrobium species used for herbal medicines based on ribosomal DNA internal transcribed spacer sequence
    Tomoko Takamiya
    School of Pharmacy, Nihon University, Japan
    Biol Pharm Bull 34:779-82. 2011
    ..denudans, D. eriiflorum, D. gregulus, or D. hemimelanoglossum were also used as sources. Furthermore, it is clear that D. catenatum is one of the most important sources of Dendrobii Herba (5 out of 21 samples)...
  28. ncbi request reprint Anti-allergic agents from natural sources (4): anti-allergic activity of new phloroglucinol derivatives from Mallotus philippensis (Euphorbiaceae)
    Akihiro Daikonya
    College of Pharmacy, Nihon University, Chiba, Japan
    Chem Pharm Bull (Tokyo) 50:1566-9. 2002
    ..Furthermore, they inhibited histamine release from rat peritoneal mast cells induced by Compound 48/80. These results suggest that the novel phloroglucinol derivatives have anti-inflammatory effects...
  29. doi request reprint New cytotoxic diarylheptanoids from the rhizomes of Alpinia officinarum
    Yi Sun
    College of Pharmacy, Nihon University, Chiba, Japan
    Planta Med 74:427-31. 2008
    ..Among the tested compounds, 11, 12 and 14 exhibited the most potent activities with IC (50) values of 0.83, 0.23 and 0.11 microM, respectively...
  30. ncbi request reprint Auxins affected ginsenoside production and growth of hairy roots in Panax hybrid
    Daisuke Washida
    College of Pharmacy, Nihon University, Funabashi, Chiba, Japan
    Biol Pharm Bull 27:657-60. 2004
    ..The highest yield of ginsenoside was obtained when cultured with 0.5 microM IBA and 1.0 microM IBA combination (6.38 mg per a flask, at week 8)...
  31. doi request reprint Inhibitory effects of constituents from Euphorbia lunulata on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells
    Zhi Gang Yang
    School of Pharmacy, Nihon University, 7 7 1 Narashinodai, Funabashi, Chiba 274 8555, Japan
    Molecules 16:8305-18. 2011
    ..7 cells...
  32. ncbi request reprint New cannabinoid-like chromane and chromene derivatives from Rhododendron anthopogonoides
    Naoki Iwata
    School of Pharmacy, Nihon University, Funabashi, Chiba 274 8555, Japan
    Chem Pharm Bull (Tokyo) 59:1409-12. 2011
    ..The absolute configuration of the asymmetric carbons at C-2 of 1-7 was determined to be S from their circular dichroism (CD) spectra. Compounds 2, 4 and 6 inhibited compound 48/80-induced histamine release from rat peritoneal mast cells...
  33. ncbi request reprint Mechanism of proliferation arrest of embryonic cells of Xenopus by diterpene compounds
    Tomoharu Okouchi
    Laboratory of Biochemistry, Department of Chemistry, College of Humanities and Sciences, Nihon University, 3 25 40 Sakurajosui, Setagaya Ku, Tokyo 156 8550, Japan
    Bioorg Med Chem 13:3847-51. 2005
    ..While kansuinin B and 20-OD-ingenol Z treatment decreased the cell numbers in the S phase and the M phase substages of the cell cycle, 20-OD-ingenol E inhibited mitosis...
  34. ncbi request reprint Effect of Coriolis force on counter-current chromatographic separation by centrifugal partition chromatography
    Jun Ichi Ikehata
    Division of Analytical Chemistry, College of Pharmacy, Nihon University, 7 7 1, Narashinodai 7 Chome, Funabashi shi, Chiba 274 8555, Japan
    J Chromatogr A 1025:169-75. 2004
    ..The overall results demonstrated that the Coriolis force produces substantial effects on CPC separation in both organic-aqueous and aqueous-aqueous two-phase systems...