Atsushi Hirayama

Summary

Affiliation: Nihon University
Country: Japan

Publications

  1. ncbi request reprint Qualitative and quantitative changes in coronary plaque associated with atorvastatin therapy
    Atsushi Hirayama
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, and Department of Cardiology, The Cardiovascular Institute Hospital, Tokyo, Japan
    Circ J 73:718-25. 2009
  2. pmc High HbA1c levels correlate with reduced plaque regression during statin treatment in patients with stable coronary artery disease: results of the coronary atherosclerosis study measuring effects of rosuvastatin using intravascular ultrasound in Japanese
    Hiroyuki Daida
    Department of Cardiology, Juntendo University School of Medicine, 2 1 1 Hongo, Tokyo 113 8421, Japan
    Cardiovasc Diabetol 11:87. 2012
  3. ncbi request reprint Plaque-stabilizing effect of atorvastatin is stronger for plaques evaluated as more unstable by angioscopy and intravenous ultrasound
    Atsushi Hirayama
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 75:1448-54. 2011
  4. doi request reprint Effect of catheter tip-tissue surface contact on three-dimensional left atrial and pulmonary vein geometries: potential anatomic distortion of 3D ultrasound, fast anatomical mapping, and merged 3D CT-derived images
    Yasuo Okumura
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    J Cardiovasc Electrophysiol 24:259-66. 2013
  5. ncbi request reprint Abnormal atrial repolarization and depolarization contribute to the inducibility of atrial fibrillation in Brugada syndrome
    Masayoshi Kofune
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 51:159-65. 2010
  6. doi request reprint Development of a model for prediction of coronary atherosclerotic regression: evaluation of high-density lipoprotein cholesterol level and peripheral blood monocyte count
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo 101 8309, Japan
    Heart Vessels 27:143-50. 2012
  7. ncbi request reprint P wave morphology of an arrhythmogenic focus in patients with atrial fibrillation originating from a pulmonary vein or the superior vena cava
    Kimie Ohkubo
    Division of Cardiology, Department of Cardiovascular Disease, Nihon University School of Medicine, Tokyo, Japan
    Circ J 72:1650-7. 2008
  8. doi request reprint Continuous low-dose infusion of human atrial natriuretic peptide in patients with left ventricular dysfunction undergoing coronary artery bypass grafting: the NU-HIT (Nihon University working group study of low-dose Human ANP Infusion Therapy during cardi
    Akira Sezai
    Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan
    J Am Coll Cardiol 55:1844-51. 2010
  9. ncbi request reprint Right ventricular histological substrate and conduction delay in patients with Brugada syndrome
    Kimie Ohkubo
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine
    Int Heart J 51:17-23. 2010
  10. ncbi request reprint Rate-dependent electrophysiologic effects of the class III antiarrhythmic drugs nifekalant, amiodarone, and ibutilide on the atrium in patients with persistent atrial fibrillation
    Kazumasa Sonoda
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine
    Int Heart J 54:279-84. 2013

Detail Information

Publications98

  1. ncbi request reprint Qualitative and quantitative changes in coronary plaque associated with atorvastatin therapy
    Atsushi Hirayama
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, and Department of Cardiology, The Cardiovascular Institute Hospital, Tokyo, Japan
    Circ J 73:718-25. 2009
    ..The aim of this study was to elucidate the time course of atorvastatin-induced changes in vulnerable plaque using angioscopy and intravascular ultrasound (IVUS)...
  2. pmc High HbA1c levels correlate with reduced plaque regression during statin treatment in patients with stable coronary artery disease: results of the coronary atherosclerosis study measuring effects of rosuvastatin using intravascular ultrasound in Japanese
    Hiroyuki Daida
    Department of Cardiology, Juntendo University School of Medicine, 2 1 1 Hongo, Tokyo 113 8421, Japan
    Cardiovasc Diabetol 11:87. 2012
    ..5 mg once daily, up-titrated to a maximum of 20 mg/day to achieve LDL cholesterol <80 mg/dl)...
  3. ncbi request reprint Plaque-stabilizing effect of atorvastatin is stronger for plaques evaluated as more unstable by angioscopy and intravenous ultrasound
    Atsushi Hirayama
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 75:1448-54. 2011
    ..The aim of this study was to compare the effect of atorvastatin treatment on high-grade yellow coronary plaques (grade ≥ 2, group H) vs. low-grade yellow plaques (grade ≤ 1, group L)...
  4. doi request reprint Effect of catheter tip-tissue surface contact on three-dimensional left atrial and pulmonary vein geometries: potential anatomic distortion of 3D ultrasound, fast anatomical mapping, and merged 3D CT-derived images
    Yasuo Okumura
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    J Cardiovasc Electrophysiol 24:259-66. 2013
    ..Our data reveal anatomic distortion of 3D images, providing important information for improving the safety and efficacy of 3D mapping-guided AF ablation. (J Cardiovasc Electrophysiol, Vol. 24, pp. 259-266, March 2013)...
  5. ncbi request reprint Abnormal atrial repolarization and depolarization contribute to the inducibility of atrial fibrillation in Brugada syndrome
    Masayoshi Kofune
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 51:159-65. 2010
    ..Both abnormal interatrial conduction and steep restitution of action potential duration may contribute to the atrial arrhythmogenicity in Brugada syndrome...
  6. doi request reprint Development of a model for prediction of coronary atherosclerotic regression: evaluation of high-density lipoprotein cholesterol level and peripheral blood monocyte count
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo 101 8309, Japan
    Heart Vessels 27:143-50. 2012
    ..6% showed the increase of the plaque volume (2.6%). In view of the inflammatory nature of atherosclerosis, the model constructed using the two predictors may be a useful model for the prediction of plaque regression...
  7. ncbi request reprint P wave morphology of an arrhythmogenic focus in patients with atrial fibrillation originating from a pulmonary vein or the superior vena cava
    Kimie Ohkubo
    Division of Cardiology, Department of Cardiovascular Disease, Nihon University School of Medicine, Tokyo, Japan
    Circ J 72:1650-7. 2008
    ..It was hypothesized that atrial premature contractions (APCs) originating in the pulmonary veins (PVs) or superior vena cava (SVC) can be localized by evaluating characteristics of the P wave...
  8. doi request reprint Continuous low-dose infusion of human atrial natriuretic peptide in patients with left ventricular dysfunction undergoing coronary artery bypass grafting: the NU-HIT (Nihon University working group study of low-dose Human ANP Infusion Therapy during cardi
    Akira Sezai
    Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan
    J Am Coll Cardiol 55:1844-51. 2010
    ..Continuous low-dose infusion of human atrial natriuretic peptide (hANP) in patients undergoing cardiac surgery on cardiopulmonary bypass (CPB) inhibits the renin-angiotensin-aldosterone system and compensates for the adverse effects of CPB...
  9. ncbi request reprint Right ventricular histological substrate and conduction delay in patients with Brugada syndrome
    Kimie Ohkubo
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine
    Int Heart J 51:17-23. 2010
    ..Slow conduction at the RVOT may contribute to the induction of VF by PVS in Brugada syndrome. Various pathomorphologic changes may contribute to slow conduction at the RVOT...
  10. ncbi request reprint Rate-dependent electrophysiologic effects of the class III antiarrhythmic drugs nifekalant, amiodarone, and ibutilide on the atrium in patients with persistent atrial fibrillation
    Kazumasa Sonoda
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine
    Int Heart J 54:279-84. 2013
    ....
  11. ncbi request reprint A novel technique for improved lesions in the coronary sinus. comparison of bipolar and unipolar ablation
    Kimie Ohkubo
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 53:129-32. 2012
    ..However, the incidence of steam pop tended to be increased with bipolar ablation.Bipolar ablation of the CS appears to be highly effective for creating a transmural LA-CS lesion...
  12. doi request reprint Does location of epicardial adipose tissue correspond to endocardial high dominant frequency or complex fractionated atrial electrogram sites during atrial fibrillation?
    Koichi Nagashima
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ Arrhythm Electrophysiol 5:676-83. 2012
    ..Therefore, we investigated whether EAT locations were associated with high dominant frequency (DF) sites or complicated fractionated atrial electrogram sites during AF...
  13. ncbi request reprint Epicardial ablation with irrigated electrodes: – effect of bipolar vs. unipolar ablation on lesion formation –
    Koichi Nagashima
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 76:322-7. 2012
    ..Ablation of ventricular tachycardia originating from the left ventricular (LV) epicardium is often limited by the radiofrequency power delivery. We compared the effect of bipolar vs. unipolar epicardial ablation on lesion size...
  14. ncbi request reprint Diagnostic value of adenosine-induced left ventricular diastolic dysfunction for detecting coronary artery restenosis in patients undergoing stent implantation by Stress ECG-gated myocardial perfusion SPECT. A pilot study
    Yoshimochi Nakano
    Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 74:2658-65. 2010
    ....
  15. doi request reprint Relationship between status of plasma atrial natriuretic peptide and heart rate variability in human subjects
    Yuji Kasamaki
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30 1 Ooyaguchi Kamimachi, Itabashiku, Tokyo, 173 8610, Japan
    Heart Vessels 28:208-14. 2013
    ..These findings are consistent with the previous report of a close relationship between ANP and cardiac parasympathetic and/or sympathetic activity...
  16. ncbi request reprint Incremental prognostic value of cardiac function assessed by ECG-gated myocardial perfusion SPECT for the prediction of future acute coronary syndrome
    Naoya Matsumoto
    Department of Cardiology, Nihon University School of Medicine, Tokyo
    Circ J 72:2035-9. 2008
    ....
  17. ncbi request reprint Combined effect of pulmonary vein isolation and ablation of cardiac autonomic nerves for atrial fibrillation
    Kimie Ohkubo
    Department of Cardiovascular Disease, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 49:661-70. 2008
    ..GP can be identified by endocardial stimulation. The AF recurrence rate is decreased when a vagal response is achieved by radiofrequency ablation...
  18. ncbi request reprint Clarifying the arrhythmogenic substrate for Brugada syndrome
    Masayoshi Kofune
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 52:290-4. 2011
    ..Our data suggest that regional endocardial conduction slowing based on structural abnormalities exists at the RVOT in Brugada syndrome...
  19. ncbi request reprint Use of a novel irrigated balloon catheter to generate continuous right atrial lesions by radiofrequency ablation
    Ichiro Watanabe
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 50:365-76. 2009
    ..No coagulum formation was observed after RF energy delivery. A long lesion can be created in the right atrium by using an irrigated balloon catheter, but continuous lesion formation was achieved only in a minority of animals...
  20. ncbi request reprint Temperature-controlled cooled-tip radiofrequency linear ablation of the atria guided by a realtime position management system
    Ichiro Watanabe
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Japan
    Int Heart J 52:50-5. 2011
    ..Further studies are needed to determine whether such an ablation technique and the parameters used will facilitate successful completion of the catheter-based maze procedure...
  21. ncbi request reprint Temperature-controlled cooled-tip radiofrequency ablation in left ventricular myocardium
    Ichiro Watanabe
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30 1 Oyaguchi Kami, Itabashi ku, Tokyo 173 8610, Japan
    Int Heart J 51:193-8. 2010
    ..9 + or - 1.1 mm, and lesion volume was 281 + or - 210 mm(3).Temperature controlled RFCA is feasible with a cooled-tip catheter and an RF generator that slowly increases the RF power until the preset catheter-tip temperature is reached...
  22. doi request reprint Comparative distribution of complex fractionated atrial electrograms, high dominant frequency (HDF) sites during atrial fibrillation and HDF sites during sinus rhythm
    Masayoshi Kofune
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Ohyaguchi kamicho, Itabashi ku, Tokyo, Japan, 173 8610
    J Interv Card Electrophysiol 36:297-306. 2013
    ..HDF sites in sinus rhythm (SR-HDF; as defined by frequencies of >70 Hz) are suggested to be abnormal atrial tissue. Relations between these electrophysiologic signals have not been elucidated...
  23. doi request reprint Plaque stabilization by intensive LDL-cholesterol lowering therapy with atorvastatin is delayed in type 2 diabetic patients with coronary artery disease-Serial angioscopic and intravascular ultrasound analysis
    Tadateru Takayama
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    J Cardiol 61:381-6. 2013
    ..The study purpose was to compare DM and non-DM (nDM) patients in terms of statin-induced change of plaque characteristics using intravascular ultrasound (IVUS) and coronary angioscopy...
  24. doi request reprint Impact of biomarkers of inflammation and extracellular matrix turnover on the outcome of atrial fibrillation ablation: importance of matrix metalloproteinase-2 as a predictor of atrial fibrillation recurrence
    Yasuo Okumura
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    J Cardiovasc Electrophysiol 22:987-93. 2011
    ..AF is associated with inflammation and subsequent myocardial fibrosis. We therefore examined the possibility of determining the postablation prognosis of patients with AF using biomarkers of inflammation and collagen turnover...
  25. ncbi request reprint Association between epicardial adipose tissue volumes on 3-dimensional reconstructed CT images and recurrence of atrial fibrillation after catheter ablation
    Koichi Nagashima
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 75:2559-65. 2011
    ..Whether epicardial adipose tissue (EAT) is independently associated with atrial fibrillation (AF) and outcome after catheter ablation (CA) for AF remains unclear...
  26. ncbi request reprint Myocardial protective effect of human atrial natriuretic Peptide in cardiac surgery. -hANP Shot” in clinical safety trial-
    Akira Sezai
    Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan
    Circ J 75:2144-50. 2011
    ..The efficacy of a bolus injection of hANP (the "hANP shot") simultaneously with induction of cardioplegia has been proven in animal experiments. In the present study the clinical effects of this "hANP shot" were examined...
  27. ncbi request reprint Combined assessment of myocardial perfusion and function by ECG-gated myocardial perfusion single-photon emission computed tomography for the prediction of future cardiac events in patients with type 2 diabetes mellitus
    Masahiko Kato
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 75:376-82. 2011
    ..In the present study rates of future cardiac events (nonfatal acute myocardial infarction (AMI), cardiac death (CD) and severe heart failure (HF) requiring hospitalization) were compared in patients with and without DM...
  28. ncbi request reprint Prognostic value of non-obstructive CT low-dense coronary artery plaques detected by multislice computed tomography
    Naoya Matsumoto
    Department of Cardiology, Nihon University School of Medicine, Tokyo, Japan
    Circ J 71:1898-903. 2007
    ....
  29. ncbi request reprint Three-dimensional high-density bipolar contact mapping of left atrial endocardial activation during sinus rhythm in patients with atrial fibrillation
    Kazumasa Sonoda
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine
    Int Heart J 54:285-8. 2013
    ....
  30. doi request reprint Prevalence of prominent J waves in patients presenting with ventricular fibrillation without structural heart disease: a single-center study
    Kimie Ohkubo
    Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    J Cardiol 59:313-20. 2012
    ..There appears to be an increased prevalence of J-wave syndrome among patients with a history of idiopathic ventricular fibrillation...
  31. ncbi request reprint Linear catheter ablation of the right atrium for rapid atrial pacing-induced sustained atrial fibrillation in dogs
    Ichiro Watanabe
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 53:375-82. 2012
    ..Therefore, RA linear lesions in addition to the PVI and LA lesions may have additional effects on the catheter ablation for the persistent AF...
  32. doi request reprint Feasibility of landiolol and bisoprolol for prevention of atrial fibrillation after coronary artery bypass grafting: a pilot study
    Akira Sezai
    Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan
    J Thorac Cardiovasc Surg 144:1241-8. 2012
    ..In the present study, we investigated the efficacy of increasing the dose and administration period of landiolol for prevention of postoperative AF, as well as the effect of oral bisoprolol in the early postoperative period...
  33. doi request reprint Efficacy and feasibility of pericardial endoscopy by a subcutaneous approach
    Koichi Nagashima
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30 1 Oyaguchi kamicho, Itabashi ku, Tokyo 173 8610, Japan
    Europace 13:1501-3. 2011
    ..The endoscopic pericardial procedure was successful and may increase the efficacy and safety of epicardial irrigated radiofrequency catheter ablation...
  34. ncbi request reprint Pharmacologic atrial defibrillation by drug delivery into the temporarily occluded coronary sinus. A canine study
    Ichiro Watanabe
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 53:125-8. 2012
    ....
  35. doi request reprint Effects of inter-electrode spacing on complex fractionated atrial electrograms and dominant frequency detection
    Koichi Nagashima
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30 1 Ohyaguchi Kamicho, Itabashi ku, Tokyo, 173 8610, Japan
    J Interv Card Electrophysiol 34:51-7. 2012
    ..The influence of inter-electrode spacing (IES) on complex fractionated atrial electrograms (CFAEs) and dominant frequency (DF) detection was assessed...
  36. ncbi request reprint Effects of the antianginal drug trapidil on atrioventricular conduction disturbances during acute myocardial ischemia
    Ichiro Watanabe
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 53:187-92. 2012
    ..AV conduction disturbances associated with inferior myocardial infarction may be related in part to endogenously released adenosine, and trapidil may be useful in treating AV block associated with acute AV node ischemia...
  37. ncbi request reprint Combined effect of disopyramide and erythromycin on ventricular repolarization in dogs with complete atrioventricular block
    Ichiro Watanabe
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 52:393-7. 2011
    ..Similar trends occurred in group 2. These results indicate a potentially fatal interaction between DP and EM administered in clinically relevant doses...
  38. ncbi request reprint Low-density lipoprotein cholesterol/apolipoprotein B ratio may be a useful index that differs in statin-treated patients with and without coronary artery disease: a case control study
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Int Heart J 52:343-7. 2011
    ..Such monitoring is particularly important in patients with elevated serum TG levels, which is associated with smaller sizes of LDL-particles...
  39. ncbi request reprint Prolonged QRS duration in lead V2 and risk of life-threatening ventricular Arrhythmia in patients with Brugada syndrome
    Kimie Ohkubo
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 52:98-102. 2011
    ..Prolonged QRS duration as measured on a standard 12-lead ECG is associated with ventricular arrhythmia and could serve as a simple noninvasive marker of vulnerability to life-threatening cardiac events in patients with Brugada syndrome...
  40. ncbi request reprint Electrical remodeling in fibrillating canine atrium: action potential alternans during rapid atrial pacing and late phase 3 early afterdepolarization after cessation of rapid atrial pacing
    Ichiro Watanabe
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 51:354-8. 2010
    ....
  41. doi request reprint A quantitative and qualitative analysis of the virtual unipolar electrograms from non-contact mapping of right or left-sided outflow tract premature ventricular contractions/ventricular tachycardia origins
    Yasuo Okumura
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30 1 Ohyaguchi kami machi, Itabashi ku, Tokyo 173 8610, Japan
    J Interv Card Electrophysiol 30:17-25. 2011
    ....
  42. ncbi request reprint Effect of the ATP-sensitive K⁺ channel opener nicorandil in a canine model of proarrhythmia
    Ichiro Watanabe
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 52:318-22. 2011
    ..It suppressed EADs, decreased the incidence of PVCs, and abolished PVT. Nicorandil may be clinically useful for treatment of PVCs and PVTs accompanying acquired long QT syndrome...
  43. ncbi request reprint Coronary plaque regression and lifestyle modification in patients treated with pravastatin. - Assessment mainly by daily aerobic exercise and an increase in the serum level of high-density lipoprotein cholesterol -
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Circ J 74:954-61. 2010
    ..The purpose of this study was to explore the effect of lifestyle modification, mainly daily aerobic exercise, on coronary atherosclerosis in patients with coronary artery disease (CAD)...
  44. ncbi request reprint Action potential alternans in the right ventricular outflow tract in a patient with asymptomatic Brugada syndrome
    Masayoshi Kofune
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 73:580-3. 2009
    ..Monophasic action potentials (MAPs) recorded from the RVOT at a BCL of 400 ms showed MAP alternans and VF was only induced when extrastimuli were applied after a shorter MAP of the alternans...
  45. ncbi request reprint Three-dimensional reconstruction of the coronary sinus with rotational angiography
    Masayoshi Kofune
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 72:1020-1. 2008
    ..High-speed rotational coronary venous (CV) angiography (RCVA) permits dynamic, multi-angle visualization of the CV anatomy...
  46. doi request reprint Association of leukocyte subtype counts with coronary atherosclerotic regression following pravastatin treatment
    Shigemasa Tani
    Department of Cardiology, Nihon University, Surugadai Hospital, Tokyo, Japan
    Am J Cardiol 104:464-9. 2009
    ..In conclusion, the decrease in monocyte count as a nonlipid-lowering effect of statins may be used as a novel marker of coronary atherosclerotic regression...
  47. doi request reprint Relation of change in apolipoprotein B/apolipoprotein A-I ratio to coronary plaque regression after Pravastatin treatment in patients with coronary artery disease
    Shigemasa Tani
    Department of Cardiology, Nihon University, Surugadai Hospital, Tokyo, Japan
    Am J Cardiol 105:144-8. 2010
    ..0023). In conclusion, our results have indicated that the decrease in the apoB/apoA-I ratio is a simple predictor for coronary atherosclerotic regression: the lower the apoB/apoA-I ratio, the lower the risk of coronary atherosclerosis...
  48. doi request reprint Full-motion two- and three-dimensional pulmonary vein imaging by intracardiac echocardiography after pulmonary vein isolation
    Yasuo Okumura
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Pacing Clin Electrophysiol 31:409-17. 2008
    ..An imaging technique that accurately portrays the pulmonary vein (PV) anatomy would be valuable during and after catheter ablation procedures...
  49. ncbi request reprint Surface ECG characteristics of ventricular tachyarrhythmias before degeneration into ventricular fibrillation in patients with Brugada-type ECG
    Kimie Ohkubo
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 50:477-87. 2009
    ..The majority of the patients with Brugada syndrome showed repetitive VT originating from the RVOT that degenerated into VF. The RVOT may be an arrhythmogenic focus in patients with Brugada syndrome...
  50. doi request reprint Potential anatomic substrate of peri-atrioventricular nodal atrial tachycardia ablated from the noncoronary sinus of Valsalva
    Hiroaki Mano
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30 1 Ohyaguchi kami cho, Itabashi ku, Tokyo, 173 8610, Japan
    J Interv Card Electrophysiol 38:27-34. 2013
    ..Although focal atrial tachycardia (AT) is known to sometimes be ablated from the noncoronary aortic cusp (NCC), the electro-anatomic characteristics of NCC-AT are not well known...
  51. doi request reprint Risk stratification of cardiovascular events in patients at all stages of chronic kidney disease using myocardial perfusion SPECT
    Shunichi Yoda
    Department of Cardiology, Nihon University School of Medicine, Tokyo, Japan
    J Cardiol 60:377-82. 2012
    ..We evaluated the ability of electrocardiogram (ECG)-gated myocardial perfusion single photon emission computed tomography (SPECT) to predict cardiac events among Japanese patients at all stages of CKD including those on hemodialysis...
  52. ncbi request reprint Association of cholesteryl ester transfer protein mass with peripheral leukocyte count following statin therapy: a pilot study
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Am J Cardiovasc Drugs 12:349-54. 2012
    ..However, the role of the CETP mass in the development of atherosclerosis is still unclear...
  53. doi request reprint Characteristics and distribution of complex fractionated atrial electrograms and the dominant frequency during atrial fibrillation: relationship to the response and outcome of circumferential pulmonary vein isolation
    Yasuo Okumura
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Ohyaguchi kamicho, Itabashi ku, Tokyo, Japan
    J Interv Card Electrophysiol 34:267-75. 2012
    ....
  54. ncbi request reprint A new criteria differentiating type 2 and 3 Brugada patterns from ordinary incomplete right bundle branch block
    Kimie Ohkubo
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 52:159-63. 2011
    ..9 ± 12.9°, n = 6, versus 38.7 ± 16.5°, n = 13; P = 0.009). This ECG-based method successfully discriminates between the ordinary iRBBB pattern and drug-induced evolution toward a type 1 Brugada ECG...
  55. doi request reprint Whole-heart coronary magnetic resonance angiography of double left anterior descending artery
    Satoshi Kunimoto
    Department of Cardiology, Nihon University School of Medicine, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo, 101 8309, Japan
    Heart Vessels 23:363-5. 2008
    ..We describe, for the first time, three-dimensional, whole-heart coronary magnetic resonance angiographic findings of double left anterior descending artery...
  56. ncbi request reprint Abnormal action potential duration restitution property in the right ventricular outflow tract in Brugada syndrome
    Sonoko Ashino
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 74:664-70. 2010
    ....
  57. doi request reprint Anatomic and electrophysiologic differences between chronic and paroxysmal atrial flutter: intracardiac echocardiographic analysis
    Kimie Ohkubo
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Oyaguchi kami, Itabashi ku, Tokyo, Japan
    Pacing Clin Electrophysiol 31:432-7. 2008
    ..It remains unknown why atrial flutter (AFL) occurs as either a chronic or paroxysmal arrhythmia...
  58. doi request reprint Landiolol hydrochloride for prevention of atrial fibrillation after coronary artery bypass grafting: new evidence from the PASCAL trial
    Akira Sezai
    Department of Cardiovascular Surgery, Nihon University School of Medicine, Itabashi ku, Tokyo, Japan
    J Thorac Cardiovasc Surg 141:1478-87. 2011
    ..We investigated whether landiolol hydrochloride, an ultrashort-acting beta-blocker, could reduce postoperative atrial fibrillation in a randomized controlled trial...
  59. doi request reprint Functional atrioventricular conduction block in an elderly patient with acquired long QT syndrome: elucidation of the mechanism of block
    Kimie Ohkubo
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Itabashi ku, Tokyo, Japan
    J Electrocardiol 44:353-6. 2011
    ..However, 2:1 HV block developed at a pacing cycle length of 500 milliseconds. Intravenous administration of mexiletine decreased the cycle length of developing HV block to 360 milliseconds...
  60. doi request reprint Upper turnaround point of the reentry circuit of common atrial flutter--three-dimensional mapping and entrainment study
    Yasuo Okumura
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30 1 Ohyaguchi kami machi, Itabashi ku, Tokyo 173 8610, Japan
    J Interv Card Electrophysiol 29:147-56. 2010
    ..The aim of this study was to determine the upper turnaround site of the AFL circuit by means of three-dimensional (3D) mapping and entrainment pacing...
  61. doi request reprint Diagnostic value of automated quantification of nuclear cardiology in Japanese patients with single vessel coronary artery disease: comparison between Japanese and American normal databases
    Shunichi Yoda
    Department of Cardiology, Nihon University School of Medicine, Tokyo, Japan Electronic address
    J Cardiol 62:224-9. 2013
    ....
  62. ncbi request reprint Lesion formation by ventricular septal ablation with irrigated electrodes: comparison of bipolar and sequential unipolar ablation
    Koichi Nagashima
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30 1 Oyaguchi kamicho, Itabashi ku, Tokyo 173 8610, Japan
    Circ J 75:565-70. 2011
    ..We compared the efficacy of bipolar ablation vs. sequential unipolar ablation in creating a transmural lesion across the porcine IVS...
  63. doi request reprint Left bundle branch block-type ventricular tachycardia originating from the left ventricular septum in a patient with cardiac sarcoidosis
    Yasuo Okumura
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Ohyaguchi kami machi, Itabashi ku, Tokyo 173 8610, Japan
    J Interv Card Electrophysiol 26:181-4. 2009
    ..A point ablation at that LV site could successfully terminate the VT, suggesting that a critical isthmus was located on the LV side of the interventricular septum despite the demonstration of an LBBB-type VT...
  64. doi request reprint Results of low-dose human atrial natriuretic peptide infusion in nondialysis patients with chronic kidney disease undergoing coronary artery bypass grafting: the NU-HIT (Nihon University working group study of low-dose HANP Infusion Therapy during cardiac
    Akira Sezai
    Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan
    J Am Coll Cardiol 58:897-903. 2011
    ..The purpose of this comparative study is to prove the efficacy of the human atrial natriuretic peptide (hANP) in patients with chronic kidney disease (CKD) undergoing coronary artery bypass graft surgery (CABG)...
  65. ncbi request reprint Radiofrequency catheter ablation of ventricular tachycardia originating in the left posterior and left anterior fascicles in a patient with prior myocardial infarction
    Sonoko Ashino
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 49:119-27. 2008
    ..A Purkinje potential preceded onset of the local ventricular potential by 120-130 ms in this VT. Radiofrequency ablation guided by the Purkinje potential terminated the VT2...
  66. ncbi request reprint Idiopathic ventricular fibrillation characterized by spatial heterogeneity of action potential duration and its restitution kinetics
    Sonoko Ashino
    Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Int Heart J 49:733-40. 2008
    ..4 versus 1.0). Such spatial heterogeneity of the MAPD and of its restitution may facilitate wavebreak and functional reentry, predisposing to VF...
  67. doi request reprint Efficacy of aggressive lipid controlling therapy for preventing saphenous vein graft disease
    Mitsumasa Hata
    Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan
    Ann Thorac Surg 88:1440-4. 2009
    ..5 for preventing postcoronary bypass (CABG) saphenous vein graft (SVG) diseases by using intracoronary angioscopy...
  68. ncbi request reprint Effect of rosuvastatin on coronary atheroma in stable coronary artery disease: multicenter coronary atherosclerosis study measuring effects of rosuvastatin using intravascular ultrasound in Japanese subjects (COSMOS)
    Tadateru Takayama
    Division of Cardiology, Nihon University School of Medicine, Tokyo, Japan
    Circ J 73:2110-7. 2009
    ..The effect of rosuvastatin on plaque volume in patients with stable coronary artery disease (CAD), including those receiving prior lipid-lowering therapy, was examined in the present study...
  69. ncbi request reprint Effects of quinidine on the action potential duration restitution property in the right ventricular outflow tract in patients with brugada syndrome
    Sonoko Ashino
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 75:2080-6. 2011
    ..The effects of quinidine gluconate, a potent inhibitor of I(to), on RVOT action potential duration (APD) restitution kinetics in patients with Brugada syndrome were evaluated...
  70. doi request reprint Influence of continuous infusion of low-dose human atrial natriuretic peptide on renal function during cardiac surgery: a randomized controlled study
    Akira Sezai
    Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan
    J Am Coll Cardiol 54:1058-64. 2009
    ..The purpose of this study was to determine the effect of human atrial natriuretic peptide (hANP) in patients who underwent coronary artery bypass grafting (CABG) on renal function...
  71. doi request reprint Study of the factors related to atrial fibrillation after coronary artery bypass grafting: a search for a marker to predict the occurrence of atrial fibrillation before surgical intervention
    Akira Sezai
    Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan
    J Thorac Cardiovasc Surg 137:895-900. 2009
    ..In this study we studied various factors in addition to trying to identify a marker that would predict the potential for atrial fibrillation before surgical intervention to prevent its occurrence...
  72. doi request reprint Amlodipine suppressed cardiac gene expression of brain natriuretic peptide, transforming growth factor-β₁ and fibronectin mediated by aldosterone in male stroke-prone spontaneously hypertensive rats
    Shinsuke Harasawa
    Department of Cardiology, Nihon University Surugadai Hospital Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    J Pharm Pharmacol 62:1740-5. 2010
    ..We evaluated whether the calcium channel blocker confers cardiac protection through the renin-angiotensin-aldosterone system in male stroke-prone spontaneously hypertensive rats (SHR-SP)...
  73. ncbi request reprint Comparison of endocardial and epicardial lesion size following large-tip and extra-large-tip transcatheter cryoablation
    Kenichi Hashimoto
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 73:1619-26. 2009
    ..An increased lesion size if the cryoablation catheter profile and catheter tip length were increased was hypothesized...
  74. ncbi request reprint Mid-ventricular obstructive hypertrophic cardiomyopathy with apical aneurysm: Report of 2 cases
    Yuichi Sato
    Department of Cardiology, Nihon University School of Medicine, Tokyo, Japan
    Int J Cardiol 129:e88-90. 2008
    ..Echocardiography revealed asymmetric septal hypertrophy and mid-ventricular obstruction with pressure gradient within the left ventricle and cine magnetic resonance imaging showed an apical aneurysm in both cases...
  75. doi request reprint Ventricular fibrillation induced by radiofrequency ablation for slow ventricular tachycardia associated with left ventricular dysfunction
    Masayoshi Kofune
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Itabashi ku, Tokyo, Japan
    J Electrocardiol 44:87-91. 2011
    ..The PVC/VT focus might have served as an abnormal automatic trigger and driver for the ventricular fibrillation...
  76. ncbi request reprint Low invasive angiogenic therapy for myocardial infarction by retrograde transplantation of mononuclear cells expressing the VEGF gene
    Kazuhiro Hagikura
    Department of Advanced Medicine, Nihon University School of Medicine, Division of Cell Regeneration and Transplantation, 30 1, Oyaguchi, Kami machi, Itabashi ku, 173 8610, Tokyo, Japan
    Int J Cardiol 142:56-64. 2010
    ..We examined the effects of transplantation of peripheral MNCs expressing an exogenous vascular endothelial growth factor (VEGF) gene in a pig model of acute myocardial infarction (AMI)...
  77. doi request reprint Long-term results (three-year) of emergency coronary artery bypass grafting for patients with unstable angina pectoris
    Akira Sezai
    Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan
    Am J Cardiol 106:511-6. 2010
    ..The best results are obtained by combining good surgical technique and perioperative management with the long-term outcome in mind...
  78. ncbi request reprint Fifteen years of experience with ATS mechanical heart valve prostheses
    Akira Sezai
    Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo 173 8610, Japan
    J Thorac Cardiovasc Surg 139:1494-500. 2010
    ..ATS Medical, Inc, developed a mechanical heart valve that has been in use since 1992. In this article, we present the results of 15 years of follow-up of patients who have undergone ATS heart valve replacement at our hospital...
  79. doi request reprint Stent thrombosis and drug-eluting stents
    Tadateru Takayama
    Division of Cardiology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan
    J Cardiol 58:92-8. 2011
    ..Further studies of larger multicenter trials would give us insight into the specific mechanisms of stent thrombosis among different generations of DES...
  80. doi request reprint Treatment of coronary spastic angina with a statin in addition to a calcium channel blocker: a pilot study
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    J Cardiovasc Pharmacol 52:28-34. 2008
    ..The results showed that improvement of lipid metabolism, especially an increase of HDL cholesterol level and a reduction of MDA-LDL, may inhibit vascular contractility...
  81. doi request reprint Local conduction block of the atria by premature stimulus in a patient with Brugada syndrome
    Ichiro Watanabe
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    J Electrocardiol 43:74-5. 2010
    ..However, MAP at a coupling interval of 210 milliseconds was 112 milliseconds, and local activation of S2 failed to spread to the rest of atrium...
  82. ncbi request reprint Relationship between plasma homocysteine levels and congestive heart failure in patients with acute myocardial infarction. Homocysteine and congestive heart failure
    Takehiko Washio
    Department of Cardiology, Nihon University Surugadai Hospital, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo, Japan
    Int Heart J 52:224-8. 2011
    ..8 µmol/L or higher was a risk factor for the development of heart failure (HR: 7.175, P < 0.01). The plasma homocysteine level in patients with AMI may be related to the development of heart failure...
  83. doi request reprint Automated versus manual measurement of the QT interval and corrected QT interval
    Yuji Kasamaki
    Department of Medicine, Division of Cardiology, Nihon University School of Medicine, Tokyo, Japan
    Ann Noninvasive Electrocardiol 16:156-64. 2011
    ..The International Conference on Harmonization E14 Guideline specifies detailed assessment of QT interval or corrected QT interval prolongation when developing new drugs. We recently devised new software to precisely measure the QT interval...
  84. ncbi request reprint Cardiac resynchronization and cardioverter defibrillation therapy in a patient with isolated noncompaction of the ventricular myocardium
    Katsuaki Okubo
    Department of Cardiology, Nihon University School of Medicine, Tokyo, Japan
    Int J Cardiol 136:e66-8. 2009
    ..In this report, we describe a patient with INVM in whom cardiac resynchronization and cardioverter defibrillation therapy was effective for the improvement of left ventricular function and for the prevention of ventricular arrhythmias...
  85. ncbi request reprint First case report in Japan of left ventricular pacing via a coronary vein in a patient with a mechanical tricuspid valve
    Masataka Yoda
    Department of Thoracic andCardiovascular Surgery, Nihon University School of Medicine, 30 1Ooyaguchi kamimachi, Itabashi ku, Tokyo 173 8610, Japan
    Circ J 72:335-6. 2008
    ..Coronary vein leads enable a minimally invasive approach, improve safety, and give effective stimulation for patients with a prosthetic tricuspid valve. This is the first case report in Japan of left ventricular pacing in such a patient...
  86. ncbi request reprint Non-invasive assessment and clinical strategy of stable coronary artery disease by magnetic resonance imaging, multislice computed tomography and myocardial perfusion SPECT
    Naoya Matsumoto
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Japan
    Circ J 74:34-40. 2010
    ..Circ J 2010; 74: 34 - 40)...
  87. ncbi request reprint Enhanced response from the caudal pressor area in spontaneously hypertensive rats
    Yoshiharu Yajima
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30 1 Oyaguchi Kamimachi, Tokyo 173 8610, Japan
    Brain Res 1227:89-95. 2008
    ..Therefore, the enhancement of sympathoexcitatory vasomotor drive evoked from the CPA may, at least in part, support elevated AP and regulate sympathetic tone in this hypertensive model...
  88. ncbi request reprint Use of bepridil in combination with Ic antiarrhythmic agent in converting persistent atrial fibrillation to sinus rhythm
    Shinobu Imai
    Department of Cardiology, Nihon University Surugadai Hospital, Nihon University School of Medicine, Tokyo, Japan
    Circ J 72:709-15. 2008
    ..The conversion effect of bepridil alone is not always satisfactory, however. The efficacy of pharmacological cardioversion by the combination of bepridil and a class Ic antiarrhythmic drug for persistent AF is studied...
  89. ncbi request reprint Influence of genetic polymorphisms in oxidative stress related genes and smoking on plasma MDA-LDL, soluble CD40 ligand, E-selectin and soluble ICAM1 levels in patients with coronary artery disease
    Takahiro Ueno
    Department of Medicine, Division of Nephrology, Hypertension and Endocrinology, Nihon University School of Medicine, Tokyo, Japan
    Med Sci Monit 15:CR341-8. 2009
    ..Previous studies have shown that oxidative stress plays an important role in coronary heart disease. Polymorphisms in key enzymes that regulate oxidative stress may play a role in atherogenicity and were investigated in this study...
  90. ncbi request reprint Alcohol produces imbalance of adrenal and neuronal sympathetic activity in patients with alcohol-induced neurocardiogenic syncope
    Naoyuki Takahashi
    Department of Cardiology, Surugadai Nihon University Hospital, Tokyo, Japan
    Circ J 72:979-85. 2008
    ..The mechanism of alcohol-induced syncope is unknown...
  91. ncbi request reprint Efficacy of continuous low-dose hANP administration in patients undergoing emergent coronary artery bypass grafting for acute coronary syndrome
    Akira Sezai
    Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo, Japan
    Circ J 71:1401-7. 2007
    ..In the present study, the efficacy of the therapy during emergent coronary artery bypass grafting (CABG) for acute coronary syndrome (ACS) is investigated...
  92. ncbi request reprint Randomized study of angiotensin II type 1 receptor blocker vs dihydropiridine calcium antagonist for the treatment of paroxysmal atrial fibrillation in patients with hypertension
    Takeshi Yamashita
    J RHYTHM II Clinical Trial Center, The Cardiovascular Institute, Roppongi, Tokyo, Japan
    Circ J 70:1318-21. 2006
    ..One candidate is the so-called "upstream therapy", which refers to the blockade of upstream modifying elements (renin - angiotensin system, cathecholamines, oxidative stress etc) that contribute to the arrhythmogenic substrate...
  93. ncbi request reprint Multislice computed tomographic findings of the anomalous origins of the right coronary artery: evaluation of possible causes of myocardial ischemia
    Makoto Ichikawa
    Department of Cardiology, Nihon University School of Medicine, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo 101 8309, Japan
    Int J Cardiovasc Imaging 23:353-60. 2007
    ..Anomalous right coronary arteries (RCA) arising from the left sinus of Valsalva may cause myocardial ischemia...
  94. ncbi request reprint Electrocardiographic and electrophysiologic characteristics in patients with Brugada type electrocardiogram and inducible ventricular fibrillation: single center experience
    Kimie Ohkubo
    Department of Cardiovascular Disease, Nihon University School of Medicine, Tokyo, Japan
    Circ J 71:1437-41. 2007
    ..The study examined the electrocardiographic and electrophysiologic characteristics in relation to programmed ventricular stimulation (PVS)-induced ventricular fibrillation (VF) in patients with Brugada syndrome...
  95. ncbi request reprint Prognostic value of myocardial perfusion single-photon emission computed tomography for the prediction of future cardiac events in a Japanese population: a middle-term follow-up study
    Naoya Matsumoto
    Department of Cardiology, Nihon University School of Medicine, 1 8 13 Kanda Surugadai, Chiyoda ku, Tokyo 101 8309, Japan
    Circ J 71:1580-5. 2007
    ....
  96. doi request reprint Association of circulating leukocyte count with coronary atherosclerosis regression after pravastatin treatment
    Shigemasa Tani
    Department of Cardiology, Nihon University Surugadai Hospital, Tokyo, Japan
    Atherosclerosis 198:360-5. 2008
    ..In conclusion, a reduction of the leukocyte count as one of the non-lipid-lowering effects of pravastatin may be a novel marker of regression of coronary atherosclerosis...
  97. ncbi request reprint Endocardial electrograms from the right ventricular outflow tract after induced ventricular fibrillation in patients with Brugada syndrome
    Kimie Ohkubo
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan
    Circ J 71:1258-62. 2007
    ..The aim of this study was to investigate the role of slow conduction for the initiation of VF by PVS in these patients...
  98. ncbi request reprint [Coronary stenting for acute coronary syndrome]
    Tadateru Takayama
    Division of Cardiology, Nihon University School of Medicine
    Nihon Rinsho 68:674-9. 2010
    ..Distal protection device has been attracted attention to new trend for ACS patients. Coronary stent is going to new generation and stenting for ACS is also changing in near future...