Research Topics
Genomes and Genes
| M YamamotoSummaryAffiliation: National Defense Medical College Country: Japan Publications
| Collaborators
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Detail Information
Publications
Use of serial analysis of gene expression (SAGE) technologyM Yamamoto
Department of Biochemistry, National Defense Medical College, 3 2 Namiki, Tokorozawa, 359 8513, Saitama, Japan
J Immunol Methods 250:45-66. 2001..This may be another problem we have to keep in mind, when the profiles are compared for the identification of 'specific genes'...
Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 siteT Oyake
Department of Biochemistry, Tohoku University School of Medicine, Sendai, Japan
Mol Cell Biol 16:6083-95. 1996..The results suggest that members of the Bach family play important roles in coordinating transcription activation and repression by MafK...
Mesodermal- vs. neuronal-specific expression of MafK is elicited by different promotersH Motohashi
Department of Biochemistry, Tohoku University School of Medicine, Aoba ku, Sendai, Japan
Genes Cells 1:223-38. 1996....
Cloning of a coproporphyrinogen oxidase promoter regulatory element binding proteinS Takahashi
Department of Biochemistry, Tohoku University School of Medicine, Sendai, 980 8575, Japan
Biochem Biophys Res Commun 273:596-602. 2000..These results indicate that Klp1 is a DNA sequence-specific transcription factor that regulates gene expression of genes that contain CPRE in their regulatory region...
A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/POZ domainA Kobayashi
Department of Biochemistry, Tohoku University School of Medicine, Sendai 980 8575, Japan
Mol Cell Biol 20:1733-46. 2000..The results provide a new perspective on the function of BTB/POZ domain factors and indicate that BTB/POZ domain-mediated oligomers of transcription factors may serve as combinatorial codes for gene expression...
Identification and characterization of genes associated with human hepatocellular carcinogenesisN Kondoh
Department of Biochemistry II, National Defense Medical College, Saitama, Japan
Cancer Res 59:4990-6. 1999..These transcripts are differentially regulated depending on cell-cell contact, serum growth factors, growth and differentiation status, and/or other mechanisms in premalignant and malignant liver cells...
Osteoclastogenesis inhibitory factor exhibits hypocalcemic effects in normal mice and in hypercalcemic nude mice carrying tumors associated with humoral hypercalcemia of malignancyT Akatsu
Third Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
Bone 23:495-8. 1998..Furthermore, it is suggested that OCIF has therapeutic potential for the treatment of hypercalcemic conditions such as malignancy-associated hypercalcemia...
The promoter of mouse transcription repressor bach1 is regulated by Sp1 and trans-activated by Bach1J Sun
Department of Biochemistry, Hiroshima University School of Medicine, Kasumi Hiroshima 734-8551, Japan
J Biochem 130:385-92. 2001..Such a positive feedback regulation by the repressor Bach1 may play an important role in maintaining the expression of Bach1 while consolidating repression of other genes with MARE...
Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteinsK Igarashi
Department of Biochemistry, Tohoku University School of Medicine, Sendai, Japan
Nature 367:568-72. 1994....
Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3A Kobayashi
Department of Biochemistry, Tohoku University School of Medicine, 2 1 Seiryomachi, Aoba ku, Sendai 980 8575, Japan
J Biol Chem 274:6443-52. 1999....
GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesisK Onodera
Department of Biochemistry, Tohoku University School of Medicine, Sendai 980 77, Japan
Proc Natl Acad Sci U S A 94:4487-92. 1997....
Oxidative stress abolishes leptomycin B-sensitive nuclear export of transcription repressor Bach2 that counteracts activation of Maf recognition elementH Hoshino
Department of Biochemistry, Tohoku University School of Medicine, Seiryo machi 2 1, Sendai 980 8575, Japan
J Biol Chem 275:15370-6. 2000..The results suggest that Bach2 mediates nucleocytoplasmic communication to couple oxidative stress and transcription repression in mammalian cells...
Differential regulation of coproporphyrinogen oxidase gene between erythroid and nonerythroid cellsS Takahashi
Department of Biochemistry, Tohoku University School of Medicine, Sendai, Japan
Blood 92:3436-44. 1998..These results provide evidence for differential regulation of the promoter function of CPO gene between erythroid and nonerythroid cells...
Long range interaction of cis-DNA elements mediated by architectural transcription factor Bach1C Yoshida
Department of Biochemistry, Tohoku University School of Medicine, Sendai 980 8575, Japan
Genes Cells 4:643-55. 1999..Bach1 forms heterodimers with small Maf proteins through its leucine zipper and binds to Maf recognition elements (MARE)...
Differential roles of GATA-1 and GATA-2 in growth and differentiation of mast cellsH Harigae
Department of Biochemistry, Tohoku University School of Medicine, Sendai, Japan
Genes Cells 3:39-50. 1998..To address this question, the expression of GATA-1 and GATA-2 mRNAs and proteins were examined in three mouse mast cell progenitor lines as well as in mast cells isolated from both wild-type and GATA-1-deficient mice...
Species-specific interaction of transcription factor p70 with the rDNA core promoterK Yamamoto
Department of Biochemistry, Saitama Medical School, 38 Morohongo, Saitama, Moroyama, Iruma-gun, 350-0495, Japan
Biochem Biophys Res Commun 281:1001-5. 2001..In contrast, human p70 no longer bound to the human core promoter when mouse SL1 was used. Thus, a species-specific interaction between p70 and SL1 may be involved in the promoter selection for rDNA transcription...
Genetic and epigenetic events in human hepatocarcinogenesisN Kondoh
Department of Biochemistry II, National Defense Medical College, Saitama 359-8513, Japan
Int J Oncol 18:1271-8. 2001....
Enhanced expression of S8, L12, L23a, L27 and L30 ribosomal protein mRNAs in human hepatocellular carcinomaN Kondoh
Second Department of Biochemistry, National Defense Medical College, Saitama, Japan
Anticancer Res 21:2429-33. 2001..The expression of these mRNAs was also high in three human HCC cell lines (HuH-7, HepG2 and HLF), irrespective of the growth state. These results suggest that activation of these genes is an important manifestation of HCC phenotypes...
Stimulation of MCM3 gene expression in osteoblast by low level laser irradiationM Yamamoto
Department of Biochemistry, Nihon University School of Dentistry at Matsudo, Chiba, Japan
Lasers Med Sci 16:213-7. 2001..These findings suggest that low-level laser irradiation may enhance DNA replication and play a role in stimulating proliferation of osteoblast through the enhancement of the MCM3 gene expression...
Involvement of calcium-calmodulin protein kinase but not mitogen-activated protein kinase in light-induced phase delays and Per gene expression in the suprachiasmatic nucleus of the hamsterS Yokota
Department of Pharmacology and Brain Science Waseda University, Tokorozawa, Saitama, Japan
J Neurochem 77:618-27. 2001..These results suggest that gated induction of Per1 and/or Per2 genes through CaMKII-CREB/CRE accompanied with photic stimuli may be a critical step in phase shifting...
Differentiation-dependent enhanced expression of protein phosphatase 2Cbeta in germ cells of mouse seminiferous tubulesS Kato
Department of Biochemistry, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan
FEBS Lett 396:293-7. 1996....
Transforming growth factor-beta1 increases mRNA levels of osteoclastogenesis inhibitory factor in osteoblastic/stromal cells and inhibits the survival of murine osteoclast-like cellsT Murakami
Third Department of Internal Medicine, Second Department of Biochemistry, National Defense Medical College, Namiki 3 2, Saitama, Tokorozawa, 359 8513, Japan
Biochem Biophys Res Commun 252:747-52. 1998....
Reactivation of rat insulin-like growth factor II gene during hepatocarcinogenesisT Ueno
Department of Biochemistry, Kyushi University, Fukuoka, Japan
Carcinogenesis 9:1779-83. 1988..Consistently high levels of expression were observed in all primary tumors, but the relative promoter activity varied with the tumor. The significance of rIGFII reactivation was discussed in the light of the hepatocarcinogenesis...
Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cellsK Yomogida
Department of Biochemistry, Tohoku University School of Medicine, Japan
Development 120:1759-66. 1994..These observations suggest that transcription factor GATA-1 is a developmental stage- and spermatogenic cycle-specific regulator of gene expression in Sertoli cells...
Induction of murine intestinal and hepatic peroxiredoxin MSP23 by dietary butylated hydroxyanisoleT Ishii
Department of Biochemistry, Institute of Basic Medical Sciences, Tsukuba Advanced Research Alliance Center, Institute of Clinical Sciences, University of Tsukuba, 1 1 1 Tennoudai, Tsukuba, Ibaraki, Japan
Carcinogenesis 21:1013-6. 2000..The induction of MSP23 may be important to protect the cells and tissues against toxic electrophiles and reactive oxygen species...
Structure of the gene encoding rat neutrophil chemo-attractant GroK Konishi
Department of Biochemistry, Toyama Medical and Pharmaceutical University Faculty of Medicine, Japan
Gene 126:285-6. 1993..The 5'-flanking region of the gene contained a 'TATA'-like structure and an NF-kappa B-binding sequence...
A distinct mRNA encoding a soluble form of ICAM-1 molecule expressed in human tissuesT Wakatsuki
Department of Biochemistry II, National Defense Medical College, Saitama, Japan
Cell Adhes Commun 3:283-92. 1995..Inflammatory cytokines displayed a complex pattern in the ICAM-1 mRNA expression depending on the combination of cytokines and the cultured cell lines used...
Isolation and characterization of cDNA encoding mouse RNA polymerase II subunit RPB14Y Nishi
Department of Biochemistry, Saitama Medical School, Iruma gun, Japan
Gene 187:165-70. 1997..A possible role of the alpha-motif [Dequard-Chablat, M., Riva, M., Carles, C. and Sentenac, A., J. Biol. Chem. 266 (1991) 15300-15307] in the protein-protein interaction between mRPA40 and mRPB14 is also discussed...
Attenuation of brain derived neurotrophic factor (BDNF) by ethanol and cytoprotective effect of exogenous BDNF against ethanol damage in neuronal cellsR Sakai
Department of Biochemistry, Sapporo Medical University School of Medicine, Sapporo, Japan
J Neural Transm 112:1005-13. 2005..Exogenous BDNF was shown to have a protective effect against ethanol-induced damage in primary culture neurons from rat hippocampi...
Comparison of hypocalcemic hypercalciuria between patients with idiopathic hypoparathyroidism and those with gain-of-function mutations in the calcium-sensing receptor: is it possible to differentiate the two disorders?M Yamamoto
Third Department of Internal Medicine, National Defense Medical College, Saitama, Japan
J Clin Endocrinol Metab 85:4583-91. 2000....
R411C mutation of the ALAS2 gene encodes a pyridoxine-responsive enzyme with low activityK Furuyama
Department of Biochemistry, Tohoku University School of Medicine, Sendai, Japan
Br J Haematol 103:839-41. 1998..These findings suggest that the R411C mutation accounts for low ALAS activity and a partial pyridoxine-responsiveness of the disease in the patient...
Activity and expression of murine small Maf family protein MafKK Igarashi
Department of Biochemistry, Tohoku University School of Medicine, Sendai, Japan
J Biol Chem 270:7615-24. 1995..mRNA for MafK is expressed in fractions enriched for hematopoietic stem cells as well as erythroid cells, suggesting that MafK plays an important regulatory role in hematopoiesis...
Basic fibroblast growth factor promotes proliferation of rat glomerular visceral epithelial cells in vitroA Takeuchi
Department of Pathology, National Defense Medical College, Saitama, Japan
Am J Pathol 141:107-16. 1992..In a word, bFGF may be produced by vGEC and stored in the ECM, that is the GBM, and may be one factor that stimulates vGEC to proliferate when vGEC are injured and lost in vivo...
Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteinsK Itoh
Department of Biochemistry, Tohoku University School of Medicine, Sendai, Japan
Mol Cell Biol 15:4184-93. 1995..In a transfection assay, ECH transactivates transcription depending on the presence of NF-E2 sites on the reporter gene plasmid. These results indicate that ECH is likely a key regulator of avian erythropoiesis...
Functional analysis of multiple promoters of the rat insulin-like factor II geneT Matsuguchi
Department of Biochemistry, Kyushu University, Fukuoka, Japan
Biochim Biophys Acta 1048:165-70. 1990....
