Takenori Yamaguchi

Summary

Affiliation: National Cardiovascular Center
Country: Japan

Publications

  1. ncbi Optimal intensity of warfarin therapy for secondary prevention of stroke in patients with nonvalvular atrial fibrillation : a multicenter, prospective, randomized trial. Japanese Nonvalvular Atrial Fibrillation-Embolism Secondary Prevention Cooperative St
    T Yamaguchi
    National Cardiovascular Center, Osaka, Japan
    Stroke 31:817-21. 2000
  2. ncbi Alteplase at 0.6 mg/kg for acute ischemic stroke within 3 hours of onset: Japan Alteplase Clinical Trial (J-ACT)
    Takenori Yamaguchi
    National Cardiovascular Center, Suita, Osaka, Japan
    Stroke 37:1810-5. 2006
  3. ncbi Low levels of plasma soluble receptor for advanced glycation end products are associated with severe leukoaraiosis in acute stroke patients
    Chiaki Yokota
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center Suita, Osaka, Japan
    J Neurol Sci 287:41-4. 2009
  4. ncbi Mortality and cause of death after hospital discharge in 10,981 patients with ischemic stroke and transient ischemic attack
    Kazumi Kimura
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Osaka City, Japan
    Cerebrovasc Dis 19:171-8. 2005
  5. ncbi Albuminuria, but not metabolic syndrome, is a significant predictor of stroke recurrence in ischemic stroke
    Chiaki Yokota
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center Suita, Osaka, Japan
    J Neurol Sci 277:50-3. 2009
  6. ncbi Characteristics of in-hospital onset ischemic stroke
    Kazumi Kimura
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Osaka, Japan
    Eur Neurol 55:155-9. 2006
  7. ncbi Extracorporeal double filtration plasmapheresis in acute atherothrombotic brain infarction caused by major artery occlusive lesion
    Yasuhiro Hasegawa
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Suita, Osaka, Japan
    J Clin Apher 18:167-74. 2003
  8. ncbi A case-control analysis of intra-arterial urokinase thrombolysis in acute cardioembolic stroke
    Takeshi Inoue
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Suita-city, Osaka, Japan
    Cerebrovasc Dis 19:225-8. 2005
  9. ncbi Predictors of clinical outcome in patients receiving local intra-arterial thrombolysis without subsequent symptomatic intracranial hemorrhage against acute middle cerebral artery occlusion
    Tatsuro Takada
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan
    AJNR Am J Neuroradiol 25:1796-801. 2004
  10. ncbi Effects of perindopril-based blood pressure lowering and of patient characteristics on the progression of silent brain infarct: the Perindopril Protection against Recurrent Stroke Study (PROGRESS) CT Substudy in Japan
    Yasuhiro Hasegawa
    Cerebrovascular Division, National Cardiovascular Center, 5 7 1, Fujishirodai, Suita 565 8565, Japan
    Hypertens Res 27:147-56. 2004

Detail Information

Publications39

  1. ncbi Optimal intensity of warfarin therapy for secondary prevention of stroke in patients with nonvalvular atrial fibrillation : a multicenter, prospective, randomized trial. Japanese Nonvalvular Atrial Fibrillation-Embolism Secondary Prevention Cooperative St
    T Yamaguchi
    National Cardiovascular Center, Osaka, Japan
    Stroke 31:817-21. 2000
    ..We studied the efficacy and safety of conventional- and low-intensity warfarin therapy in a prospective, randomized, multicenter trial...
  2. ncbi Alteplase at 0.6 mg/kg for acute ischemic stroke within 3 hours of onset: Japan Alteplase Clinical Trial (J-ACT)
    Takenori Yamaguchi
    National Cardiovascular Center, Suita, Osaka, Japan
    Stroke 37:1810-5. 2006
    ..6 mg/kg, which is lower than the internationally approved dosage of 0.9 mg/kg, aiming to assess the efficacy and safety of alteplase in acute ischemic stroke for the Japanese...
  3. ncbi Low levels of plasma soluble receptor for advanced glycation end products are associated with severe leukoaraiosis in acute stroke patients
    Chiaki Yokota
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center Suita, Osaka, Japan
    J Neurol Sci 287:41-4. 2009
    ..RAGE signaling can contribute to the deterioration of neuronal damage under severe leukoaraiosis, result in a high NIHSS score on admission in acute stroke patients, especially those with smoking habits...
  4. ncbi Mortality and cause of death after hospital discharge in 10,981 patients with ischemic stroke and transient ischemic attack
    Kazumi Kimura
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Osaka City, Japan
    Cerebrovasc Dis 19:171-8. 2005
    ....
  5. ncbi Albuminuria, but not metabolic syndrome, is a significant predictor of stroke recurrence in ischemic stroke
    Chiaki Yokota
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center Suita, Osaka, Japan
    J Neurol Sci 277:50-3. 2009
    ..005-3.350) in ischemic stroke. There were no significant predictors of stroke recurrence in patients with brain hemorrhage. In conclusion, albuminuria, but not MetS, was a significant predictor of stroke recurrence in ischemic stroke...
  6. ncbi Characteristics of in-hospital onset ischemic stroke
    Kazumi Kimura
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Osaka, Japan
    Eur Neurol 55:155-9. 2006
    ..The aim of the present study was to clarify the clinical characteristics of in-hospital onset stroke...
  7. ncbi Extracorporeal double filtration plasmapheresis in acute atherothrombotic brain infarction caused by major artery occlusive lesion
    Yasuhiro Hasegawa
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Suita, Osaka, Japan
    J Clin Apher 18:167-74. 2003
    ..In conclusion, EDFP can increase CBF in ischemic brain tissue in acute atherothrombotic brain infarction. Further clinical studies should focus on the efficacy of EDFP on outcome of patients with this stroke subtype...
  8. ncbi A case-control analysis of intra-arterial urokinase thrombolysis in acute cardioembolic stroke
    Takeshi Inoue
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Suita-city, Osaka, Japan
    Cerebrovasc Dis 19:225-8. 2005
    ..CONCLUSIONS: IA-UK thrombolytic therapy may improve the outcome in hyperacute cardioembolic stroke patients...
  9. ncbi Predictors of clinical outcome in patients receiving local intra-arterial thrombolysis without subsequent symptomatic intracranial hemorrhage against acute middle cerebral artery occlusion
    Tatsuro Takada
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan
    AJNR Am J Neuroradiol 25:1796-801. 2004
    ..CONCLUSION: Improvement of the NIHSS score by >or=2 immediately after LIT is a useful predictor of patient outcome at discharge...
  10. ncbi Effects of perindopril-based blood pressure lowering and of patient characteristics on the progression of silent brain infarct: the Perindopril Protection against Recurrent Stroke Study (PROGRESS) CT Substudy in Japan
    Yasuhiro Hasegawa
    Cerebrovascular Division, National Cardiovascular Center, 5 7 1, Fujishirodai, Suita 565 8565, Japan
    Hypertens Res 27:147-56. 2004
    ..The baseline diastolic blood pressure was an independent predictor of new SBI, but the index stroke subtype did not influence the risk of SBI...
  11. ncbi Variation in ischemic stroke frequency in Japan by season and by other variables
    Toshiyasu Ogata
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Japan
    J Neurol Sci 225:85-9. 2004
    ..CONCLUSIONS: Acute ischemic stroke displays seasonal characteristics according to gender, stroke subtype, and time of stroke onset. These results may have important clinical implications in ischemic stroke prevention...
  12. ncbi Topographic distribution of misery perfusion in relation to internal and superficial borderzones
    Shuji Arakawa
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Osaka, Japan
    AJNR Am J Neuroradiol 24:427-35. 2003
    ..These results are inconsistent with clinical observations that 80% of BZ infarctions develop superficially. Thus, hemodynamic mechanisms may not cause most superficial BZ infarctions...
  13. ncbi Predisposing factors for enlargement of intracerebral hemorrhage in patients treated with warfarin
    Masahiro Yasaka
    Department of Medicine, National Cardiovascular Center, Osaka, Japan
    Thromb Haemost 89:278-83. 2003
    ..0 at admission or for 24 h after immediate INR correction with PCC prevented ICH enlargement (OR 0.069, 95%CI 0.006-0.789, p = 0.031). An INR value of >2.0 within 24 h of ICH seems an important predisposing factor for ICH enlargement...
  14. ncbi Analysis of 16,922 patients with acute ischemic stroke and transient ischemic attack in Japan. A hospital-based prospective registration study
    Kazumi Kimura
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Suita, Osaka, Japan
    Cerebrovasc Dis 18:47-56. 2004
    ..The purpose of the present study was to clarify the present status of stroke medicine in Japan using a hospital-based, prospective registration study of 156 hospitals from all over Japan...
  15. ncbi 3D-rotational angiographic demonstration of dissection of the anterior cerebral artery
    Shoji Matsumoto
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Osaka, Japan
    Cerebrovasc Dis 20:55-8. 2005
  16. ncbi Heart and vessel pathology underlying brain infarction in 142 stroke patients
    Jun Ogata
    Department of Pathology, National Cardiovascular Center, Osaka, Japan
    Ann Neurol 63:770-81. 2008
    ..This study was designed to determine the histopathological characteristics of cardiac and vascular lesions responsible for various subtypes of ischemic stroke...
  17. ncbi Low-dose aspirin for prevention of stroke in low-risk patients with atrial fibrillation: Japan Atrial Fibrillation Stroke Trial
    Hiroshi Sato
    Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan
    Stroke 37:447-51. 2006
    ..We examined the efficacy and safety of aspirin therapy in Japanese patients with NVAF in a prospective randomized multicenter trial...
  18. ncbi Long-term prognosis, by stroke subtypes, after a first-ever stroke: a hospital-based study over a 20-year period
    Chiaki Yokota
    Cerebrovascular Laboratory, National Cardiovascular Center Research Institute, Osaka 565 8565, Japan
    Cerebrovasc Dis 18:111-6. 2004
    ..We aimed to clarify the long-term prognosis by stroke subtypes and to identify determinants for recurrence and death after a first-ever stroke...
  19. ncbi Unique profile of spreading depression in a primate model
    Chiaki Yokota
    Department of Pathogenesis, Research Institute, Osaka, Japan
    J Cereb Blood Flow Metab 22:835-42. 2002
    ..Neither spreading hypoperfusion nor persistent hypoperfusion was found. These unique features of SD in primates raise a doubt as to whether the role of SD in nonprimate animals is the same as that in stroke and migraine in humans...
  20. ncbi Small centrum ovale infarcts on diffusion-weighted magnetic resonance imaging
    Kiminobu Yonemura
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Osaka, Japan
    Stroke 33:1541-4. 2002
    ..We sought to clarify the clinical characteristics of a SCOI visualized by diffusion-weighted MRI (DWI) compared with those of a small basal ganglia infarct (SBGI)...
  21. ncbi Combined carotid and transcranial color-coded sonography in acute ischemic stroke
    Kuniyasu Wada
    Department of Medicine, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, 565-8565, Osaka, Japan
    Eur J Ultrasound 15:101-8. 2002
    ..Nineteen of them were confirmed by angiography. The combination of CD and TCCS can make an accurate diagnosis for significant occlusive lesions in brain arteries in acute stroke patients...
  22. ncbi Effects of anticoagulation on infarct size and clinical outcome in acute cardioembolic stroke
    Masayuki Wakita
    Department of Medicine, National Cardiovascular Center, Suita, Osaka, Japan
    Angiology 53:551-6. 2002
    ..6. In conclusion, anticoagulant therapy with INR > or = 1.6 appears to effectively prevent a large infarct and poor outcome, even when ischemic stroke dose occurs in patients with an emboligenic heart disease...
  23. ncbi Acetazolamide challenge test using semiquantitative 123 I-IMP SPECT for detection of cerebral misery perfusion
    Shigeru Fujimoto
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan
    J Neurol Sci 205:21-7. 2002
    ..An improvement in reduced vasodilatory capacity as determined by SPECT coincides with a reduction in OEF values...
  24. ncbi Ultrasonographic prediction of patients' outcome in hyperacute ischemic stroke
    Masatoshi Koga
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka, 565-8565, Japan
    Eur J Ultrasound 15:1-8. 2002
    ..036, odds ratio, 7.9) and early CT findings (P = 0.18). CONCLUSION: US findings of hyperacute stroke may provide a better predictor of patients' outcome...
  25. ncbi Relationship between findings of conventional and contrast-enhanced transcranial color-coded real-time sonography and angiography in patients with basilar artery occlusion
    Masatoshi Koga
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Osaka, Japan
    AJNR Am J Neuroradiol 23:568-71. 2002
    ..When examined with contrast-enhanced TCCS, a combination of absent basilar artery flow and the reversed basilar artery flow sign may be a diagnostic indicator of basilar artery occlusion...
  26. ncbi Hyperintense MCA branch sign on FLAIR-MRI
    Masatoshi Koga
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, 5 7 1 Fujishirodai, Suita, Osaka 565 8565, Japan
    J Clin Neurosci 9:187-9. 2002
    ..Ultra-early evaluation with FLAIR- and diffusion-MRI may help establish the diagnosis of acute ischaemic stroke particularly due to embolic MCA branch occlusion...
  27. ncbi [Secondary prevention of stroke]
    Takenori Yamaguchi
    Nippon Ronen Igakkai Zasshi 40:223-7. 2003
  28. ncbi Antiplatelet cilostazol is beneficial in diabetic and/or hypertensive ischemic stroke patients. Subgroup analysis of the cilostazol stroke prevention study
    Yukito Shinohara
    Federation of National Personnel Mutual Aid Associations, Tachikawa Hospital, Tachikawa, Japan
    Cerebrovasc Dis 26:63-70. 2008
    ..This study was conducted to examine the effect of such complications on recurrence of cerebral infarction, and to assess the effect of cilostazol, an antiplatelet agent, in these high-risk subjects...
  29. ncbi Impact of blood pressure control on cardiovascular events in 26,512 Japanese hypertensive patients: the Japan Hypertension Evaluation with Angiotensin II Antagonist Losartan Therapy (J-HEALTH) study, a prospective nationwide observational study
    Kazuaki Shimamoto
    Sapporo Medical University School of Medicine, Sapporo, Japan
    Hypertens Res 31:469-78. 2008
    ..BP was controlled below 140/90 mmHg in a half of the very elderly hypertensive patients in this study, and these patients also had a lower incidence of CV events...
  30. ncbi [Multicenter survey on clinical features and regional variations in acute brain infarction]
    Seiji Kazui
    Rinsho Shinkeigaku 42:736-44. 2002
    ..Drug treatments, care and hospital facilities varied among districts considerably. Nation-wide consensus for ideal treatments by each stroke category is therefore needed...
  31. ncbi Sarpogrelate-Aspirin Comparative Clinical Study for Efficacy and Safety in Secondary Prevention of Cerebral Infarction (S-ACCESS): A randomized, double-blind, aspirin-controlled trial
    Yukito Shinohara
    Department of Neurology, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, 4 2 22 Nishikicho, Tachikawa, Tokyo 190 8531, Japan
    Stroke 39:1827-33. 2008
    ..The antiplatelet agent sarpogrelate is a selective inhibitor of 5-hydroxytryptamine receptors. The purpose of this study was to compare the efficacy and safety of sarpogrelate with those of aspirin in Japanese ischemic stroke patients...
  32. ncbi A randomized, double-blind study comparing the safety and efficacy of clopidogrel versus ticlopidine in Japanese patients with noncardioembolic cerebral infarction
    Yasuo Fukuuchi
    Ashikaga Red Cross Hospital, Ashikaga, Japan
    Cerebrovasc Dis 25:40-9. 2008
    ..A comparison of both agents was therefore conducted in Japanese stroke patients...
  33. ncbi Effect of the Ca antagonist nilvadipine on stroke occurrence or recurrence and extension of asymptomatic cerebral infarction in hypertensive patients with or without history of stroke (PICA Study). 1. Design and results at enrollment
    Yukito Shinohara
    Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, Tokyo, Japan
    Cerebrovasc Dis 24:202-9. 2007
    ....
  34. ncbi Treatment of warfarin-associated intracerebral hemorrhage: literature review and expert opinion
    Maria I Aguilar
    Department of Neurology, Mayo Clinic College of Medicine, 13400 E Shea Blvd, Scottsdale, AZ 85259, USA
    Mayo Clin Proc 82:82-92. 2007
    ..Reasonable management based on expert opinion includes a wide range of additional measures to reverse anticoagulation in the absence of solid evidence...
  35. ncbi Deterioration of hemiparesis after recurrent stroke in the unaffected hemisphere: Three further cases with possible interpretation
    Shiro Yamamoto
    Department of Neurology, Kansai Rosai Hospital, Hyogo, Japan
    Cerebrovasc Dis 23:35-9. 2007
    ..Several primate and human studies have suggested the formation of newly reorganized tracts in the ipsilesional or contralesional hemisphere, but the mechanism for the formation of these tracts is still largely unknown...
  36. ncbi Lacunar syndrome associated with paradoxical brain embolism
    Yoshiomi Shimizu
    Department of Internal Medicine, Hoshigaoka Kouseinenkin Hospital, Hirakata
    Intern Med 46:1609-12. 2007
    ..We concluded that the presence of lacunar syndrome suggests that this mechanism was responsible for the paradoxical brain embolism...
  37. ncbi [Brain infarction]
    Ryoichi Otsubo
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center
    Nippon Rinsho 64:270-3. 2006
  38. ncbi Outline of the Japanese Guidelines for the Management of Stroke 2004 and subsequent revision
    Yukito Shinohara
    Federation of National Public Service Personnel Mutual Aid Associations Tachikawa Hospital, Tokyo, Japan
    Int J Stroke 3:55-62. 2008
    ..Here, we present an outline the Japanese Guidelines for the Management of Stroke 2004 in response to requests, although some updating is already needed. The first revision of the guidelines is expected to be completed in 2008...
  39. ncbi [Current and future strategies of medical therapy for acute stroke]
    Kazunori Toyoda
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center
    Nippon Rinsho 64:473-7. 2006