M Watanabe

Summary

Affiliation: National Institute of Health Sciences
Country: Japan

Publications

  1. doi request reprint Utility of the phylotoxigenic relationships among trichothecene-producing Fusarium species for predicting their mycotoxin-producing potential
    M Watanabe
    Division of Microbiology, National Institute of Health Sciences, Tokyo, Japan
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 30:1370-81. 2013
  2. pmc Fatal pneumonia caused by Penicillium digitatum: a case report
    Chiyako Oshikata
    Clinical Research Centre for Allergy and Rheumatology, National Hospital Organization, Sagamihara Hospital, 18 1 Sakuradai, Minami Ku, Sagamihara, Kanagawa, 252 0392, Japan
    BMC Pulm Med 13:16. 2013
  3. ncbi request reprint Sensitive detection of whole-genome differentiation among closely-related species of the genus Fusarium using DNA-DNA hybridization and a microplate technique
    Maiko Watanabe
    Division of Microbiology, National Institute of Health Sciences, 1 18 1 Kamiyoga, Setagaya Ku, Tokyo, Japan
    J Vet Med Sci 74:1333-6. 2012
  4. pmc Molecular phylogeny of the higher and lower taxonomy of the Fusarium genus and differences in the evolutionary histories of multiple genes
    Maiko Watanabe
    Division of Microbiology, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya Ku, Tokyo 158 8501, Japan
    BMC Evol Biol 11:322. 2011
  5. doi request reprint Evaluation of genetic markers for identifying isolates of the species of the genus Fusarium
    Maiko Watanabe
    Division of Microbiology, National Institute of Health Sciences, Tokyo, Japan
    J Sci Food Agric 91:2500-4. 2011
  6. ncbi request reprint Rapid and effective DNA extraction method with bead grinding for a large amount of fungal DNA
    M Watanabe
    Division of Microbiology, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya Ku, Tokyo 158 8501, Japan
    J Food Prot 73:1077-84. 2010
  7. doi request reprint Quantitative analysis of mycoflora on commercial domestic fruits in Japan
    Maiko Watanabe
    Division of Microbiology, National Institute of Health Sciences, 1 18 1 Kamiyoga, Stetagaya ku, Tokyo 158 8501, Japan
    J Food Prot 74:1488-99. 2011
  8. ncbi request reprint Effects of the umuDC, mucAB, and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: II. Base substitution mutagenesis
    M Watanabe
    Institute of Environmental Toxicology, Tokyo, Japan
    Mutat Res 314:39-49. 1994
  9. ncbi request reprint Comparison of the sensitivity of Salmonella typhimurium strains YG1024 and YG1012 for detecting the mutagenicity of aromatic amines and nitroarenes
    M Watanabe
    Division of Genetics and Mutagenesis, National Institute of Hygienic Sciences, Tokyo, Japan
    Mutat Res 301:7-12. 1993
  10. ncbi request reprint Increased formation of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, in human breast cancer tissue and its relationship to GSTP1 and COMT genotypes
    A Matsui
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Cancer Lett 151:87-95. 2000

Collaborators

Detail Information

Publications47

  1. doi request reprint Utility of the phylotoxigenic relationships among trichothecene-producing Fusarium species for predicting their mycotoxin-producing potential
    M Watanabe
    Division of Microbiology, National Institute of Health Sciences, Tokyo, Japan
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 30:1370-81. 2013
    ..The phylogenetic information therefore helps one to predict the mycotoxin-producing potential by Fusarium species, and these "phylotoxigenic relationships" may be useful for predicting the pathogenicity of fungi. ..
  2. pmc Fatal pneumonia caused by Penicillium digitatum: a case report
    Chiyako Oshikata
    Clinical Research Centre for Allergy and Rheumatology, National Hospital Organization, Sagamihara Hospital, 18 1 Sakuradai, Minami Ku, Sagamihara, Kanagawa, 252 0392, Japan
    BMC Pulm Med 13:16. 2013
    ..Here, we report a case of fatal pneumonia due to P. digitatum infection, as confirmed by repeated examination of cultured sputum...
  3. ncbi request reprint Sensitive detection of whole-genome differentiation among closely-related species of the genus Fusarium using DNA-DNA hybridization and a microplate technique
    Maiko Watanabe
    Division of Microbiology, National Institute of Health Sciences, 1 18 1 Kamiyoga, Setagaya Ku, Tokyo, Japan
    J Vet Med Sci 74:1333-6. 2012
    ..Our results suggest that this system is a good tool for identification and phylogenetic analysis of closely-related fungal species...
  4. pmc Molecular phylogeny of the higher and lower taxonomy of the Fusarium genus and differences in the evolutionary histories of multiple genes
    Maiko Watanabe
    Division of Microbiology, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya Ku, Tokyo 158 8501, Japan
    BMC Evol Biol 11:322. 2011
    ..There is a need not only to check substitution rates of genes but also to perform the exact evaluation of each gene-evolution...
  5. doi request reprint Evaluation of genetic markers for identifying isolates of the species of the genus Fusarium
    Maiko Watanabe
    Division of Microbiology, National Institute of Health Sciences, Tokyo, Japan
    J Sci Food Agric 91:2500-4. 2011
    ..To control fungal hazards of plants, animals and humans, there is a need for a rapid, easy and accurate identification system of Fusarium isolates with molecular methods...
  6. ncbi request reprint Rapid and effective DNA extraction method with bead grinding for a large amount of fungal DNA
    M Watanabe
    Division of Microbiology, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya Ku, Tokyo 158 8501, Japan
    J Food Prot 73:1077-84. 2010
    ..The DNA extraction methods are useful for developing gene indexes to identify fungi with molecular techniques, such as DNA fingerprinting...
  7. doi request reprint Quantitative analysis of mycoflora on commercial domestic fruits in Japan
    Maiko Watanabe
    Division of Microbiology, National Institute of Health Sciences, 1 18 1 Kamiyoga, Stetagaya ku, Tokyo 158 8501, Japan
    J Food Prot 74:1488-99. 2011
    ..These findings suggest fruits should be handled carefully with consideration given to fungal contaminants, including nonpathogenic fungi, to control the quality of fruits and processed fruit products...
  8. ncbi request reprint Effects of the umuDC, mucAB, and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: II. Base substitution mutagenesis
    M Watanabe
    Institute of Environmental Toxicology, Tokyo, Japan
    Mutat Res 314:39-49. 1994
    ..T-->C.G and A.T-->T.A transversions. The mucAB plasmid also enhanced the G.C-->A.T transitions and G.C-->C.G transversions induced by some mutagens...
  9. ncbi request reprint Comparison of the sensitivity of Salmonella typhimurium strains YG1024 and YG1012 for detecting the mutagenicity of aromatic amines and nitroarenes
    M Watanabe
    Division of Genetics and Mutagenesis, National Institute of Hygienic Sciences, Tokyo, Japan
    Mutat Res 301:7-12. 1993
    ..These results suggested that YG1024 is more suitable than YG1012 for the efficient detection of mutagenic aromatic amines and nitroarenes...
  10. ncbi request reprint Increased formation of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, in human breast cancer tissue and its relationship to GSTP1 and COMT genotypes
    A Matsui
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Cancer Lett 151:87-95. 2000
    ..At the same time, reduction of oxidative stress is thought to be a very important measure for primary prevention of breast cancer...
  11. ncbi request reprint The role of the sentinel lymph node in gastrointestinal cancer
    Y Kitagawa
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Surg Clin North Am 80:1799-809. 2000
    ....
  12. ncbi request reprint Involvement of Cys69 residue in the catalytic mechanism of N-hydroxyarylamine O-acetyltransferase of Salmonella typhimurium. Sequence similarity at the amino acid level suggests a common catalytic mechanism of acetyltransferase for S. typhimurium and high
    M Watanabe
    Division of Genetics and Mutagenesis, National Institute of Hygienic Sciences, Tokyo, Japan
    J Biol Chem 267:8429-36. 1992
    ..These results suggest that the Cys69 of S. typhimurium and its corresponding cysteine residues of the higher organisms are essential for the enzyme activities as acetyl-coenzyme A-binding sites...
  13. ncbi request reprint Effects of the umuDC, mucAB, and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: I. Frameshift mutagenesis
    M Watanabe
    Institute of Environmental Toxicology, Tokyo, Japan
    Mutat Res 314:27-37. 1994
    ..Any frameshift mutagenesis was not affected by the samAB plasmid. In general, frameshifts in adenine runs were enhanced more preferentially by the mucAB and umuDC plasmids than frameshifts at runs of guanine were...
  14. ncbi request reprint New tester strains of Salmonella typhimurium highly sensitive to mutagenic nitroarenes
    M Watanabe
    Division of Mutagenesis, National Institute of Hygienic Sciences, Tokyo, Japan
    Biochem Biophys Res Commun 147:974-9. 1987
    ..When transformed into TA1538 derivatives, these plasmids provided the basis for an extremely sensitive assay for the detection of mutagenic nitroarenes...
  15. ncbi request reprint Establishment of the human BSMZ breast cancer cell line, which overexpresses the erbB-2 and c-myc genes
    M Watanabe
    Department of Microbiology, Jikei University School of Medicine, Tokyo, Japan
    Cancer Res 52:5178-82. 1992
    ..Southern analysis has revealed amplification of the erbB-2 and c-myc loci. The BSMZ cell line may therefore provide a useful model for the study of human breast cancer and overexpression of the erbB-2 gene...
  16. ncbi request reprint Antitumor activity of hexamethylmelamine on human tumor xenografts serially transplanted in nude mice
    T Kubota
    Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
    Anticancer Res 14:2521-4. 1994
    ..HMM is thought to be a promising agent for the treatment of several types of human carcinoma, producing active metabolites in vivo after peroral administration...
  17. ncbi request reprint Tissue and organ expression of catalase in acatalasemic beagle dogs
    K Nakamura
    Analytical and Metabolic Research Laboratories, Sankyo Co, Ltd, Tokyo, Japan
    Exp Anim 48:229-34. 1999
    ..These results suggested that catalytically normal catalase protein is translated from mRNA in the tissues and organs including erythrocytes, but in erythrocytes this enzyme protein is disposed of by an unknown mechanism...
  18. ncbi request reprint Genetic determinant and environmental carcinogens
    M Nagao
    Carcinogenesis Division, National Cancer Center Research Institute, Tokyo, Japan
    Mutat Res 402:85-91. 1998
    ..By mapping the gene, we will be able to identify humans who might belong to high risk group in general population, and cancer can be prevented more efficiently by attaining early diagnosis...
  19. doi request reprint Medium-term results of neoadjuvant systemic chemotherapy using irinotecan, 5-fluorouracil, and leucovorin in patients with locally advanced rectal cancer
    Y Ishii
    Department of Surgery, Keio University School of Medicine, Shinjuku ku, Tokyo, Japan
    Eur J Surg Oncol 36:1061-5. 2010
    ....
  20. ncbi request reprint Inactivation effects of UV irradiation and ozone treatment on the yeast and the mold in mineral water
    M Watanabe
    Division of Microbiology, National Institute of Health Sciences, 1 18 1 Kamiyoga, Setagaya Ku, Tokyo 158 8501, Japan
    J Food Prot 73:1537-42. 2010
    ..Yeast cells are more sensitive to all three inactivation methods than are mold spores, and the sensitivity of yeast cells and mold spores to these inactivation methods may vary among genera...
  21. pmc N-hydroxyarylamine O-acetyltransferase of Salmonella typhimurium: proposal for a common catalytic mechanism of arylamine acetyltransferase enzymes
    M Watanabe
    Division of Genetics and Mutagenesis, National Institute of Hygienic Sciences, Tokyo, Japan
    Environ Health Perspect 102:83-9. 1994
    ..We propose a new catalytic model of acetyltransferase for S. typhimurium and the higher organisms...
  22. ncbi request reprint Chemosensitivity test is useful in evaluating the appropriate adjuvant cancer chemotherapy for stage III non-scirrhous and scirrhous gastric cancers
    S Abe
    Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
    Anticancer Res 19:4581-6. 1999
    ..These results suggested that MTT assay would be useful in evaluating the appropriate adjuvant cancer chemotherapy for stage III scirrhous and non-scirrhous gastric cancer...
  23. ncbi request reprint Inhibition of induction of adaptive response by o-vanillin in Escherichia coli B
    K Watanabe
    Institute of Environmental Toxicology, Tokyo, Japan
    Mutat Res 243:273-80. 1990
    ..The results suggest that o-vanillin inhibits induction of the adaptive response, and consequently, the MNNG-induced mutation frequency is increased due to unrepaired O6-methylguanine...
  24. ncbi request reprint Development of a syngenic brain-tumor model resistant to chloroethyl-nitrosourea using a methylguanine DNA methyltransferase cDNA
    Y Manome
    Department of Microbiology, Jikei University School of Medicine, Tokyo, Japan
    Anticancer Res 19:5313-8. 1999
    ..Because of the limited intracranial space, the animals presented a restricted survival. Since the survival was sensitive and reproducible, this system may have a role in the evaluation of approaches to drug-resistant brain-tumors...
  25. ncbi request reprint Multidrug resistance gene and P-glycoprotein expression in anaplastic carcinoma of the thyroid
    T Yamashita
    Ito Hospital, Tokyo, Japan
    Cancer Detect Prev 18:407-13. 1994
    ..However, the appearance of anticancer drug resistance in anaplastic thyroid carcinoma may not be explained solely by the expression of mdr1 and P-GP...
  26. ncbi request reprint FRS2beta, a potential prognostic gene for non-small cell lung cancer, encodes a feedback inhibitor of EGF receptor family members by ERK binding
    D Iejima
    Department of Systems Biomedical Technology, Institute of Medical Science, University of Tokyo, Minato ku, Tokyo, Japan
    Oncogene 29:3087-99. 2010
    ..Therefore, we have identified the molecular mechanisms by which FRS2beta acts as a feedback inhibitor of EGFR family members and suggest a role for FRS2beta as a tumor suppressor...
  27. doi request reprint Mitigation of occult lung injury by pneumonectomy via minithoracotomy in mice
    M Kohno
    Department of Surgery, Keio University School of Medicine, Tokyo, Japan
    Thorac Cardiovasc Surg 60:124-30. 2012
    ..The systemic and pulmonary inflammatory response associated with pneumonectomy performed via minithoracotomy versus that after open posterolateral thoracotomy is uncertain...
  28. ncbi request reprint Expression of a glutamate transporter subtype, EAAT4, in the developing human cerebellum
    M Itoh
    Department of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan
    Brain Res 767:265-71. 1997
    ..EAAT4 immunoreactivity may be related to the dendritic arborization of cells in the molecular layer...
  29. ncbi request reprint Purification and characterization of liver catalase in acatalasemic beagle dog: comparison with normal dog liver catalase
    K Nakamura
    Analytical and Metabolic Research Laboratories, Sankyo Co, Ltd, Tokyo, Japan
    Int J Biochem Cell Biol 32:89-98. 2000
    ..These results indicated that the acatalasemic dog catalase is catalytically normal although it is associated with an unstable molecular structure...
  30. doi request reprint Biological effect of tyrosine kinase inhibitors on three canine mast cell tumor cell lines with various KIT statuses
    Y Takeuchi
    Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
    J Vet Pharmacol Ther 35:97-104. 2012
    ..There was little influence of ABCB1 on TKI effects to the proliferation of VIMC1. These results will be helpful to understand the different sensitivity to TKIs in cMCT patients...
  31. ncbi request reprint Involvement of umuDCST genes in nitropyrene-induced -CG frameshift mutagenesis at the repetitive CG sequence in the hisD3052 allele of Salmonella typhimurium
    T Nohmi
    Division of Genetics and Mutagenesis, National Institute of Health Sciences, Tokyo, Japan
    Mol Gen Genet 247:7-16. 1995
    ....
  32. ncbi request reprint Enhancement effect of carteolol on the clonidine-induced vasodilation of rat mesenteric arteries
    M Ito
    Second Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan
    Pharmacol Res 31:319-23. 1995
    ..These results suggest that carteolol enhances the clonidine-induced vasodilation by an endothelial-related mechanism mediated by the release of endothelium-derived nitric oxide in resistance vessels...
  33. doi request reprint Randomised clinical trial: evaluation of the efficacy of mesalazine (mesalamine) suppositories in patients with ulcerative colitis and active rectal inflammation -- a placebo-controlled study
    M Watanabe
    Department of Gastroenterology and Hepatology, Graduate School of Tokyo Medical and Dental University, Tokyo, Japan
    Aliment Pharmacol Ther 38:264-73. 2013
    ..Mesalazine suppositories are recommended and widely used as the standard therapy in induction and maintenance of remission for proctitis...
  34. pmc Deletion mapping on chromosome 1p in well-differentiated gastric cancer
    T Ezaki
    Department of Biochemistry, Cancer Institute, Tokyo, Japan
    Br J Cancer 73:424-8. 1996
    ..3 by fluorescence in situ hybridisation, we conclude that a locus likely to contain a tumour-suppressor gene for gastric cancer is located within a 13 cM region encompassing two chromosomal bands...
  35. pmc Amnesia in frontotemporal dementia with amyotrophic lateral sclerosis, masquerading Alzheimer's disease
    A Yamanami-Irioka
    Laboratory of Structural Neuropathology, Tokyo Metropolitan Institute of Medical Science, Tokyo Medical and Dental University, Tokyo, Japan
    Case Rep Neurol 3:242-7. 2011
    ..Although the persistent elevation of creatine kinase from the onset could be a pointer to the presence of motor involvement, more accurate characterization of dementia, which may differentiate ALS-related dementia and AD, is necessary...
  36. ncbi request reprint Mucosal IL-7-mediated immune responses in chronic colitis-IL-7 transgenic mouse model
    M Watanabe
    Keio Cancer Center, Tokyo, Japan
    Immunol Res 20:251-9. 1999
    ..These findings suggest that chronic inflammation in the colonic mucosa is mediated by dysregulation of epithelial cell-derived IL-7 system...
  37. ncbi request reprint Trimethadione N-demethylation by rat liver CYP2E1 in vitro
    Y Nishimura
    Department of Pharmacology, School of Medicine, Showa University, Tokyo, Japan
    Res Commun Mol Pathol Pharmacol 93:43-56. 1996
    ..These results indicate that the CYP2E1 subfamily is the major enzyme involved in TMO N-demethylation in rat in vitro although the CYP3A2 is also involved in this transformation...
  38. pmc MOP Reduction During Long-Term Methamphetamine Withdrawal was Restored by Chronic Post-Treatment with Fluoxetine
    H Yamamoto
    Division of Psychobiology, Tokyo Institute of Psychiatry, Tokyo, Japan
    Curr Neuropharmacol 9:73-8. 2011
    ..These findings suggest that the chronic post-treatments with fluoxetine might be effective for restoring the reduction of MOP levels in the frontal cortex following long-term abstinence from methamphetamine...
  39. ncbi request reprint Effect of chronic amitriptyline administration on serotonergic receptors in rats with methylazoxymethanol-induced microencephaly
    M Watanabe
    Department of Psychopharmacology, Tokyo Institute of Psychiatry, 2 1 8 Kamikitazawa, Setagaya Ku, Tokyo 156, Japan
    Brain Res 787:333-6. 1998
    ....
  40. ncbi request reprint Ampulla cardiomyopathy ('Takotusbo' cardiomyopathy)--reversible left ventricular dysfunction: with ST segment elevation
    S Kawai
    Department of Cardiology, Juntendo University School of Medicine, Tokyo, Japan
    Jpn Circ J 64:156-9. 2000
    ..The presence of myocardial lesions suggested that focal and disseminated myocardial damage had occurred...
  41. doi request reprint Randomized clinical trial of the influence of mechanical bowel preparation on faecal microflora in patients undergoing colonic cancer resection
    M Watanabe
    Department of Gastroenterological and General Surgery, Showa University School of Medicine, Tokyo, Japan
    Br J Surg 97:1791-7. 2010
    ..This study investigated the influence of mechanical bowel preparation (MBP) on faecal microflora, using rRNA-targeted reverse transcription-quantitative polymerase chain reaction in patients undergoing colonic cancer resection...
  42. ncbi request reprint High level of CA19-9, CA50, and CEA-producible human cholangiocarcinoma cell line changes in the secretion ratios in vitro or in vivo
    M Watanabe
    Department of Microbiology, The Jikei University School of Medicine, Tokyo, Japan
    In Vitro Cell Dev Biol Anim 36:104-9. 2000
    ..The changes in the tumor marker secretion ratios were shown to be dependent upon type of tumor cells, i.e., whether they are in vitro or in vivo. These features make TK cells a valuable tool for studying tumor markers...
  43. ncbi request reprint Progression of human breast cancers to the metastatic state is linked to genotypes of catechol-O-methyltransferase
    A Matsui
    Keio Cancer Center, Tokyo, Japan
    Cancer Lett 150:23-31. 2000
    ..05). However, polymorphisms of the GSTM1 and GSTP1 gene were not associated with clinico-pathological factors. Our findings suggest that the allele encoding for low activity COMT may contribute to the progression of breast cancer...
  44. doi request reprint The chromosomal constitution of postmitotic neurons, assessed by neuronal nuclear transfer into oocytes and in ES cell lines derived from them
    T Osada
    Department of Regenerative and Developmental Biology, Mitsubishi Kagaku Institute for Life Sciences MITILS, Tokyo, Japan
    Cytogenet Genome Res 125:201-12. 2009
    ..We observed a higher incidence of chromosomal changes in N-NT than in C-NT embryos, which may reflect a higher frequency of double-stranded (ds) DNA breaks in the neuronal genome...
  45. ncbi request reprint Laparoscopic detection of sentinel lymph nodes in gastrointestinal cancer: a novel and minimally invasive approach
    Y Kitagawa
    Department of Surgery, Keio University, Tokyo, Japan
    Ann Surg Oncol 8:86S-89S. 2001
    ....
  46. ncbi request reprint Involvement of poly(ADP-ribose) polymerase in trophoblastic cell differentiation during tumorigenesis
    M Masutani
    Biochemistry Division, National Cancer Center Research Institute, Tsukiji 5 chome, Chuo Ku, 104 0045, Tokyo, Japan
    Mutat Res 477:111-7. 2001
    ..This example suggests that Parp is not essential for tumor formation, however, it is involved in trophoblastic cell differentiation and could consequently affect tumor phenotype...
  47. ncbi request reprint Purification and cloning of pierisin-2, an apoptosis-inducing protein from the cabbage butterfly, Pieris brassicae
    Y Matsushima-Hibiya
    Cancer Prevention Division, National Cancer Center Research Institute, Tokyo, Japan
    Eur J Biochem 267:5742-50. 2000
    ....