Yasue Uchida

Summary

Affiliation: National Center for Geriatrics and Gerontology
Country: Japan

Publications

  1. ncbi request reprint Diabetes reduces auditory sensitivity in middle-aged listeners more than in elderly listeners: a population- based study of age-related hearing loss
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan
    Med Sci Monit 16:PH63-8. 2010
  2. doi request reprint Contribution of 1425G/A polymorphism in protein kinase C-Eta (PRKCH) gene and brain white matter lesions to the risk of sudden sensorineural hearing loss in a Japanese nested case-control study
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Obu City, Aichi Prefecture, Japan
    J Neurogenet 25:82-7. 2011
  3. doi request reprint Molecular genetic epidemiology of age-related hearing impairment
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Japan
    Auris Nasus Larynx 38:657-65. 2011
  4. pmc Hearing impairment risk and interaction of folate metabolism related gene polymorphisms in an aging study
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, 35 Gengo, Morioka, Obu City, Aichi Prefecture 474 8511, Japan
    BMC Med Genet 12:35. 2011
  5. doi request reprint Association of the C677T polymorphism in the methylenetetrahydrofolate reductase gene with sudden sensorineural hearing loss
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Obu, Japan
    Laryngoscope 120:791-5. 2010
  6. doi request reprint The Ala54Thr polymorphism in the fatty acid-binding protein 2 (FABP2) gene is associated with hearing impairment: a preliminary report
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, 36 3 Gengo, Morioka, Obu City, Aichi Prefecture 474 8511, Japan
    Auris Nasus Larynx 37:496-9. 2010
  7. doi request reprint Endothelin-1 gene polymorphism and hearing impairment in elderly Japanese
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Obu, Japan
    Laryngoscope 119:938-43. 2009
  8. ncbi request reprint The effects of aging on distortion-product otoacoustic emissions in adults with normal hearing
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Morioka, Aichi, Japan
    Ear Hear 29:176-84. 2008
  9. ncbi request reprint Distortion product otoacoustic emissions and tympanometric measurements in an adult population-based study
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, 36 3 Gengo, Morioka, Obu, Aichi, Japan
    Auris Nasus Larynx 33:397-401. 2006
  10. doi request reprint Polymorphisms in genes encoding aquaporins 4 and 5 and estrogen receptor α in patients with Ménière's disease and sudden sensorineural hearing loss
    Naoki Nishio
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Life Sci 92:541-6. 2013

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Diabetes reduces auditory sensitivity in middle-aged listeners more than in elderly listeners: a population- based study of age-related hearing loss
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan
    Med Sci Monit 16:PH63-8. 2010
    ..Diabetes mellitus (DM) and hearing impairment are both highly prevalent in older adult populations, but how the impact of diabetes on hearing varies by age is not well-studied...
  2. doi request reprint Contribution of 1425G/A polymorphism in protein kinase C-Eta (PRKCH) gene and brain white matter lesions to the risk of sudden sensorineural hearing loss in a Japanese nested case-control study
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Obu City, Aichi Prefecture, Japan
    J Neurogenet 25:82-7. 2011
    ....
  3. doi request reprint Molecular genetic epidemiology of age-related hearing impairment
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Japan
    Auris Nasus Larynx 38:657-65. 2011
    ....
  4. pmc Hearing impairment risk and interaction of folate metabolism related gene polymorphisms in an aging study
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, 35 Gengo, Morioka, Obu City, Aichi Prefecture 474 8511, Japan
    BMC Med Genet 12:35. 2011
    ..The aim of this study is to investigate the effects of the methionine synthase (MTR) A2756G and methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphisms on the risk of hearing impairment in middle-aged and elderly Japanese...
  5. doi request reprint Association of the C677T polymorphism in the methylenetetrahydrofolate reductase gene with sudden sensorineural hearing loss
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Obu, Japan
    Laryngoscope 120:791-5. 2010
    ..To investigate the recently reported association of the C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene with sudden sensorineural hearing loss (SSNHL), we analyzed data from a community-based Japanese population...
  6. doi request reprint The Ala54Thr polymorphism in the fatty acid-binding protein 2 (FABP2) gene is associated with hearing impairment: a preliminary report
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, 36 3 Gengo, Morioka, Obu City, Aichi Prefecture 474 8511, Japan
    Auris Nasus Larynx 37:496-9. 2010
    ..The FABP2 gene has been proposed as a candidate gene for diabetes and obesity. This study evaluates the hearing impairment risk in the Ala54Thr polymorphism of FABP2 in middle-aged and elderly Japanese...
  7. doi request reprint Endothelin-1 gene polymorphism and hearing impairment in elderly Japanese
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Obu, Japan
    Laryngoscope 119:938-43. 2009
    ..To investigate the association between the Lys198Asn (G/T) polymorphism (rs5370) in the endothelin-1 gene (EDN1) and hearing impairment in middle-aged and elderly Japanese...
  8. ncbi request reprint The effects of aging on distortion-product otoacoustic emissions in adults with normal hearing
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Morioka, Aichi, Japan
    Ear Hear 29:176-84. 2008
    ..Therefore, in selecting subjects, we applied the stringent criterion in pure-tone thresholds (PTT) to limit dispersion among normal-hearing thresholds...
  9. ncbi request reprint Distortion product otoacoustic emissions and tympanometric measurements in an adult population-based study
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, 36 3 Gengo, Morioka, Obu, Aichi, Japan
    Auris Nasus Larynx 33:397-401. 2006
    ....
  10. doi request reprint Polymorphisms in genes encoding aquaporins 4 and 5 and estrogen receptor α in patients with Ménière's disease and sudden sensorineural hearing loss
    Naoki Nishio
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Life Sci 92:541-6. 2013
    ....
  11. doi request reprint Association between polymorphisms in genes encoding methylenetetrahydrofolate reductase and the risk of Ménière's disease
    Yang Huang
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    J Neurogenet 27:5-10. 2013
    ..503 (95% CI, 1.064-2.123) in model 1 and 1.505 (95% CI, 1.045-2.167) in model 2. Our results imply that the MTHFR C677T and A1298C polymorphisms are associated with the risk of MD...
  12. ncbi request reprint Prevalence of self-perceived auditory problems and their relation to audiometric thresholds in a middle-aged to elderly population
    Yasue Uchida
    Department of Otorhinolaryngology, Chubu National Hospital, Obu, Aichi, Japan
    Acta Otolaryngol 123:618-26. 2003
    ....
  13. doi request reprint Endothelin-1 gene polymorphism in sudden sensorineural hearing loss
    Yasue Uchida
    Department of Otorhinolaryngology, Aichi Medical University, Nagakute, Aichi, Japan Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Aichi, Japan
    Laryngoscope 123:E59-65. 2013
    ..This study aimed to investigate the association between the Lys198Asn (G/T) polymorphism (rs5370) of the endothelin-1 gene and sudden sensorineural hearing loss (SSNHL)...
  14. pmc Polymorphisms in genes involved in oxidative stress response in patients with sudden sensorineural hearing loss and Ménière's disease in a Japanese population
    Masaaki Teranishi
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    DNA Cell Biol 31:1555-62. 2012
    ..In conclusion, no significant associations between the polymorphisms of GPX1, PON1, PON2, and SOD2 and risk of SSNHL and Ménière's disease were observed in this Japanese case-control study...
  15. doi request reprint Polymorphisms in genes involved in inflammatory pathways in patients with sudden sensorineural hearing loss
    Mariko Hiramatsu
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    J Neurogenet 26:387-96. 2012
    ..In conclusion, the IL-6 C - 572G polymorphism is associated with a risk of SSNHL. Because permeability of blood vessels in the inner ear is frequently increased in patients with SSNHL, inflammation of the inner ear might be involved...
  16. doi request reprint Polymorphisms in genes involved in the free-radical process in patients with sudden sensorineural hearing loss and Ménière's disease
    M Teranishi
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Free Radic Res 47:498-506. 2013
    ..849 (CI, 1.033-3.310) with adjustment for age and sex. In conclusion, the NOS3 and Cav1 polymorphisms were significantly associated with the risk of SSNHL and Ménière's disease, respectively...
  17. ncbi request reprint [Analyses of factors contributing to hearing aids use and both subjective and objective estimates of hearing]
    Yasue Uchida
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Obu
    Nihon Jibiinkoka Gakkai Kaiho 111:405-11. 2008
    ..These facts implied that early-stage candidates for hearing aids may not require threshold reduction, although aided thresholds were commonly used indicators in fitting...
  18. ncbi request reprint Is there a relevant effect of noise and smoking on hearing? A population-based aging study
    Yasue Uchida
    Department of Otorhinolaryngology, Chubu National Hospital, National Institute for Longevity Sciences, Aichi, Japan
    Int J Audiol 44:86-91. 2005
    ..Smoking and noise exposure were associated with hearing loss respectively.. This result is noteworthy for the preservation of good hearing especially at the beginning of aging...
  19. doi request reprint The association between gene polymorphisms in uncoupling proteins and hearing impairment in Japanese elderly
    Saiko Sugiura
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Obu, Aichi
    Acta Otolaryngol 130:487-92. 2010
    ..This study illustrates that UCP2 Ala55Val polymorphisms exhibit a significant association with age-related hearing loss in the Japanese population...
  20. doi request reprint Tinnitus and brain MRI findings in Japanese elderly
    Saiko Sugiura
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan
    Acta Otolaryngol 128:525-9. 2008
    ..There is evidence of an inverse association between cerebral infarction and tinnitus in this study. The effects of cerebral infarction on tinnitus could be explained by a neurophysiological model of tinnitus...
  21. ncbi request reprint [Estimates of the size of the hearing-impaired elderly population in Japan and 10-year incidence of hearing loss by age, based on data from the National Institute for Longevity Sciences-Longitudinal Study of Aging (NILS-LSA)]
    Yasue Uchida
    Department of Otorhinolaryngology, Aichi Medical University, Japan
    Nihon Ronen Igakkai Zasshi 49:222-7. 2012
    ..In the present study, we analyzed the data from the National Institute for Longevity Sciences-Longitudinal Study of Aging (NILS-LSA) to ascertain the prevalence and 10-year incidence of hearing loss in Japanese elderly people...
  22. doi request reprint Contribution of complement factor H Y402H polymorphism to sudden sensorineural hearing loss risk and possible interaction with diabetes
    Naoki Nishio
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Gene 499:226-30. 2012
    ..214 (CI: 0.581-2.538) in nondiabetic subjects. We conclude that CFH Y402H polymorphism and SSNHL risk are significantly related, and that diabetic CFH Y402H minor allele carriers may be susceptible to SSNHL...
  23. ncbi request reprint [Association between cerumen impaction, cognitive function and hearing in Japanese elderly]
    Saiko Sugiura
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology
    Nihon Ronen Igakkai Zasshi 49:325-9. 2012
    ..In this study we aimed to evaluate the frequency of cerumen impaction in Japanese elderly and clarify the associations between cerumen, cognitive function, and hearing impairment...
  24. doi request reprint Contributing factors to hearing of diabetic patients in an in-hospital education program
    Satofumi Sugimoto
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Acta Otolaryngol 133:1165-72. 2013
    ..In patients with poorly controlled diabetes mellitus (DM), hearing disturbance was associated with renal dysfunction and diabetic neuropathy, represented by decreases in median nerve compound action potential amplitude...
  25. ncbi request reprint Thirty-year trends in sudden deafness from four nationwide epidemiological surveys in Japan
    Masaaki Teranishi
    Department of Otorhinolaryngology, Nagoya University, Graduate School of Medicine, Nagoya, Japan
    Acta Otolaryngol 127:1259-65. 2007
    ..Hypertension and diabetes mellitus could contribute to the etiology of this disorder...
  26. ncbi request reprint Tympanometric findings in patients with enlarged vestibular aqueducts
    Eisuke Sato
    Department of Otorhinolaryngology, Nagoya University School of Medicine, Japan
    Laryngoscope 112:1642-6. 2002
    ....
  27. doi request reprint Factors affecting fenestration of the footplate in stapes surgery: effectiveness of Fisch's reversal steps stapedotomy
    Hiromi Ueda
    Department of Otorhinolaryngology, Aichi Medical University School of Medicine, Aichi and Department of Otorhinolaryngology, Nagoya University School of Medicine, Nagoya, Japan
    Otol Neurotol 34:1576-80. 2013
    ..To analyze the factors affecting the fenestration of the footplate in stapes surgery and to evaluate the effectiveness of Fisch's reversal steps stapedotomy...
  28. ncbi request reprint [Clinical features of elderly outpatients]
    Saiko Sugiura
    Department of Otorhinolaryngology, National Center for Geriatrics and Gerontology, Obu
    Nihon Jibiinkoka Gakkai Kaiho 112:534-9. 2009
    ..It is therefore imperative to understand the clinical background of elderly patients and to concentrate on learning about and treating vertigo and hearing problems...
  29. ncbi request reprint Bezold's abscess arising with recurrent cholesteatoma 20 years after the first surgery: with a review of the 18 cases published in Japan since 1960
    Yasue Uchida
    Department of Otorhinolaryngology, National Institute for Longevity Sciences, Chubu National Hospital, 36 3 Gengo Morioka, Obu, Aichi 474 8511, Japan
    Auris Nasus Larynx 29:375-8. 2002
    ..This recent clinical presentation of Bezold's abscess is described and the Japanese literature reviewed to renew familiarity with this rare complication...