Shoichiro Tsugane

Summary

Affiliation: National Cancer Center
Country: Japan

Publications

  1. pmc Green tea drinking and subsequent risk of breast cancer in a population-based cohort of Japanese women
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Breast Cancer Res 12:R88. 2010
  2. pmc Association of postmenopausal endogenous sex hormones with global methylation level of leukocyte DNA among Japanese women
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, Tsukiji, Chuo Ku, Tokyo, Japan
    BMC Cancer 12:323. 2012
  3. doi request reprint Alcohol, smoking, and obesity epidemiology in Japan
    Shoichiro Tsugane
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    J Gastroenterol Hepatol 27:121-6. 2012
  4. pmc Validity of a self-administered food frequency questionnaire (FFQ) and its generalizability to the estimation of dietary folate intake in Japan
    Junko Ishihara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo, 104 0051, Japan
    Nutr J 4:26. 2005
  5. pmc Education level and physical functional limitations among Japanese community residents-gender difference in prognosis from stroke
    Kaori Honjo
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    BMC Public Health 9:131. 2009
  6. pmc Public awareness of risk factors for cancer among the Japanese general population: a population-based survey
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    BMC Public Health 6:2. 2006
  7. pmc Comparison of postmenopausal endogenous sex hormones among Japanese, Japanese Brazilians, and non-Japanese Brazilians
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    BMC Med 9:16. 2011
  8. ncbi request reprint Cigarette smoking and risk of stroke and its subtypes among middle-aged Japanese men and women: the JPHC Study Cohort I
    Toshifumi Mannami
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Stroke 35:1248-53. 2004
  9. doi request reprint Insulin resistance and cancer: epidemiological evidence
    Shoichiro Tsugane
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Sci 101:1073-9. 2010
  10. ncbi request reprint Salt, salted food intake, and risk of gastric cancer: epidemiologic evidence
    Shoichiro Tsugane
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045
    Cancer Sci 96:1-6. 2005

Collaborators

Detail Information

Publications147 found, 100 shown here

  1. pmc Green tea drinking and subsequent risk of breast cancer in a population-based cohort of Japanese women
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Breast Cancer Res 12:R88. 2010
    ....
  2. pmc Association of postmenopausal endogenous sex hormones with global methylation level of leukocyte DNA among Japanese women
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, Tsukiji, Chuo Ku, Tokyo, Japan
    BMC Cancer 12:323. 2012
    ..Here, we examined whether postmenopausal endogenous sex hormones were associated with the global methylation level of leukocyte DNA...
  3. doi request reprint Alcohol, smoking, and obesity epidemiology in Japan
    Shoichiro Tsugane
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    J Gastroenterol Hepatol 27:121-6. 2012
    ..1% in women. Given that many previous studies in Japanese and Asian populations have associated a low body mass index with an increased risk of cancer, the impact of being underweight--not only obese--may warrant further investigation...
  4. pmc Validity of a self-administered food frequency questionnaire (FFQ) and its generalizability to the estimation of dietary folate intake in Japan
    Junko Ishihara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo, 104 0051, Japan
    Nutr J 4:26. 2005
    ..The objectives of our study were to 1) validate a FFQ for estimating folate intake, and to identify the foods that contribute to inter-individual variation of folate intake in the Japanese population...
  5. pmc Education level and physical functional limitations among Japanese community residents-gender difference in prognosis from stroke
    Kaori Honjo
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    BMC Public Health 9:131. 2009
    ..We sought to examine the association between education level and physical functional limitations among Japanese men and women, and whether that association was modified by gender and history of stroke...
  6. pmc Public awareness of risk factors for cancer among the Japanese general population: a population-based survey
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    BMC Public Health 6:2. 2006
    ..The present study aimed to provide information on awareness of the attributable fraction of cancer causes among the Japanese general population...
  7. pmc Comparison of postmenopausal endogenous sex hormones among Japanese, Japanese Brazilians, and non-Japanese Brazilians
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    BMC Med 9:16. 2011
    ....
  8. ncbi request reprint Cigarette smoking and risk of stroke and its subtypes among middle-aged Japanese men and women: the JPHC Study Cohort I
    Toshifumi Mannami
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Stroke 35:1248-53. 2004
    ..We examined sex-specific relationships of smoking with risk of total stroke and stroke subtypes in Asian populations because of the limited data available...
  9. doi request reprint Insulin resistance and cancer: epidemiological evidence
    Shoichiro Tsugane
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Sci 101:1073-9. 2010
    ....
  10. ncbi request reprint Salt, salted food intake, and risk of gastric cancer: epidemiologic evidence
    Shoichiro Tsugane
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045
    Cancer Sci 96:1-6. 2005
    ....
  11. doi request reprint Dietary intake of folate, vitamin B2, vitamin B6, vitamin B12, genetic polymorphism of related enzymes, and risk of breast cancer: a case-control study in Japan
    Enbo Ma
    National Cancer Center, Tokyo, Japan
    Nutr Cancer 61:447-56. 2009
    ..We conclude that dietary intake of folate and related B vitamins and genotypes of MTHFR or MTR have no overall association with breast cancer risk in Japanese women...
  12. doi request reprint Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of stomach cancer: a hospital-based case-control study in Japan
    Minatsu Kobayashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Gastric Cancer 12:198-205. 2009
    ..We conducted a case-control study to investigate the association between HCA intake and stomach cancer risk. We also investigated the possible effect of genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 on stomach cancer...
  13. doi request reprint Female reproductive factors and the risk of gastric cancer in a large-scale population-based cohort study in Japan (JPHC study)
    Christina Persson
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 17:345-53. 2008
    ..Although early estrogen exposure may have some protective effect, female reproductive factors may have no substantial influence on gastric cancer development...
  14. doi request reprint Daily total physical activity level and total cancer risk in men and women: results from a large-scale population-based cohort study in Japan
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Epidemiol 168:391-403. 2008
    ..By site, decreased risks were observed for cancers of the colon, liver, and pancreas in men and for cancer of the stomach in women. Increased daily physical activity may be beneficial in preventing cancer in a relatively lean population...
  15. doi request reprint Isoflavone, polymorphisms in estrogen receptor genes and breast cancer risk in case-control studies in Japanese, Japanese Brazilians and non-Japanese Brazilians
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Cancer Sci 100:927-33. 2009
    ..21, respectively). We found no remarkable difference for the other four polymorphisms. Our findings suggest that polymorphisms in the estrogen receptor beta gene may modify the association between isoflavone intake and breast cancer risk...
  16. doi request reprint Combined impact of five lifestyle factors and subsequent risk of cancer: the Japan Public Health Center Study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Prev Med 54:112-6. 2012
    ..To evaluate whether 5 combined healthy lifestyle factors (not smoking, moderate drinking, eating minimum salt-preserved foods, being physically active, and having appropriate body mass index) are associated with reduced risk of cancer...
  17. doi request reprint Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population
    Shinobu Ikeda
    Department of Molecular Epidemiology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan
    Am J Gastroenterol 103:1476-87. 2008
    ..To investigate the association between polymorphisms and gastrointestinal (gastric and colorectal) cancer, we performed a hospital-based case-control study in Japan...
  18. doi request reprint Alcohol and risk of lung cancer among Japanese men: data from a large-scale population-based cohort study, the JPHC study
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Causes Control 19:1095-102. 2008
    ..Here, we investigated the association between alcohol consumption and lung cancer incidence...
  19. doi request reprint Association of dietary and genetic factors related to one-carbon metabolism with global methylation level of leukocyte DNA
    Hiroe Ono
    Division of Genetics, National Cancer Center Research Institute, Tokyo, Japan
    Cancer Sci 103:2159-64. 2012
    ..We found that higher folate intake was significantly associated with a lower level of global methylation of leukocyte DNA in a group of healthy Japanese females...
  20. doi request reprint Plasma levels of carotenoids, retinol and tocopherol and the risk of gastric cancer in Japan: a nested case-control study
    Christina Persson
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo ku 104 0045, Tokyo, Japan
    Carcinogenesis 29:1042-8. 2008
    ..Our findings suggest that those who have very low plasma levels of alpha-carotene and beta-carotene are at a higher risk of gastric cancer...
  21. doi request reprint Body mass index and subsequent risk of kidney cancer: a prospective cohort study in Japan
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 20:466-72. 2010
    ..Herein, we investigate the association between body mass index (BMI) and kidney cancer risk in Japanese persons, a relatively lean population...
  22. doi request reprint Body weight at age 20 years, subsequent weight change and breast cancer risk defined by estrogen and progesterone receptor status--the Japan public health center-based prospective study
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 129:1214-24. 2011
    ..50-3.34)]. Low BMI at age 20 years was substantially associated with an increased risk of breast cancer. In contrast, high recent BMI and subsequent BMI gain from age 20 were associated with increased risk of postmenopausal ER+PR+ tumors...
  23. ncbi request reprint Association between lung cancer incidence and family history of lung cancer: data from a large-scale population-based cohort study, the JPHC study
    Jun ichi Nitadori
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045 Japan
    Chest 130:968-75. 2006
    ..To clarify the possibility of a hereditary predisposition to lung cancer, we investigated the association between a family history of lung cancer and subsequent risk of lung cancer in a large-scale, population-based cohort study...
  24. doi request reprint Dietary isoflavone intake, polymorphisms in the CYP17, CYP19, 17beta-HSD1, and SHBG genes, and risk of breast cancer in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Nutr Cancer 62:466-75. 2010
    ..06-0.77). We found no remarkable difference for the rs743572 and rs10046 polymorphisms. Our findings suggest that polymorphisms in the 17beta-HSD1 and SHBG genes may modify the association between isoflavone intake and breast cancer risk...
  25. ncbi request reprint Folate, vitamin B6, vitamin B12, and vitamin B2 intake, genetic polymorphisms of related enzymes, and risk of colorectal cancer in a hospital-based case-control study in Japan
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tsukjii, Tokyo
    Nutr Cancer 53:42-50. 2005
    ..02) with colorectal cancer, although the other polymorphisms did not interact with any nutrient intake. In conclusion, the study did not support the existing hypothesis of gene-nutrient interaction in colorectal carcinogenesis...
  26. ncbi request reprint Zinc and heme iron intakes and risk of colorectal cancer: a population-based prospective cohort study in Japan
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Clin Nutr 96:864-73. 2012
    ..However, all of the studies on the association between zinc and heme iron intakes and colorectal cancer have been conducted in Western populations...
  27. doi request reprint Consumption of n-3 fatty acids and fish reduces risk of hepatocellular carcinoma
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tsukiji, Chuo ku Tokyo, Japan
    Gastroenterology 142:1468-75. 2012
    ..Although consumption of fish and n-3 PUFA has been reported to protect against the development of some types of cancer, little is known about its association with hepatocellular carcinoma (HCC)...
  28. doi request reprint Long-term dietary cadmium intake and cancer incidence
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Epidemiology 23:368-76. 2012
    ..However, data from general populations are sparse. We prospectively examined the association between cadmium exposure and incidence of cancer in a Japanese population with a relatively high dietary intake of cadmium...
  29. pmc Dietary intake of folate, vitamin B6, and vitamin B12, genetic polymorphism of related enzymes, and risk of breast cancer: a case-control study in Brazilian women
    Enbo Ma
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    BMC Cancer 9:122. 2009
    ..However, the association between B vitamin intake and breast cancer risk in Brazilian women in particular has not yet been investigated...
  30. doi request reprint Isoflavone intake and risk of gastric cancer: a population-based prospective cohort study in Japan
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Clin Nutr 95:147-54. 2012
    ..The association with gastric cancer might differ between isoflavones and soy foods, and research on the effects of isoflavone intake alone on gastric cancer is needed...
  31. doi request reprint Daily total physical activity level and premature death in men and women: results from a large-scale population-based cohort study in Japan (JPHC study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 18:522-30. 2008
    ..We prospectively examined the association between daily total physical activity level (METs/day) and subsequent risk of all-cause mortality and mortalities from cancer, heart disease, and cerebrovascular disease...
  32. ncbi request reprint Association of habitual smoking and drinking with single nucleotide polymorphism (SNP) in 40 candidate genes: data from random population-based Japanese samples
    Ying Liu
    Epidemiology and Prevention Division, Research Center of Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    J Hum Genet 50:62-8. 2005
    ..The findings of the present study suggest that polymorphism in associated candidate genes plays a role in the habitual use of tobacco and alcohol among Japanese men...
  33. doi request reprint Isoflavone consumption and subsequent risk of hepatocellular carcinoma in a population-based prospective cohort of Japanese men and women
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 124:1644-9. 2009
    ..Women with hepatitis virus infection may be advised to abstain from isoflavone consumption. Further studies are warranted to confirm these findings...
  34. doi request reprint Plasma isoflavone concentrations are not associated with gastric cancer risk among Japanese men and women
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Nutr 143:1293-8. 2013
    ..We found no association of plasma isoflavone concentrations with gastric cancer risk. Our data support the previously observed null association between isoflavone intake and gastric cancer risk...
  35. doi request reprint Impact of alcohol intake on total mortality and mortality from major causes in Japan: a pooled analysis of six large-scale cohort studies
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Epidemiol Community Health 66:448-56. 2012
    ....
  36. pmc Use of vitamin supplements and risk of total cancer and cardiovascular disease among the Japanese general population: a population-based survey
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo 104 0045, Japan
    BMC Public Health 11:540. 2011
    ..We examined whether vitamin supplement use patterns affect cancer and CVD risk in a population-based cohort study in Japan...
  37. doi request reprint Coffee, green tea, and caffeine consumption and subsequent risk of bladder cancer in relation to smoking status: a prospective study in Japan
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer Sci 100:294-91. 2009
    ..15–3.66), respectively. In conclusion, cigarette smoking was confirmed as a risk factor for bladder cancer. Coffee and caffeine may be associated with an increased bladder cancer risk in never or former smokers among Japanese men...
  38. doi request reprint Plasma isoflavone level and subsequent risk of breast cancer among Japanese women: a nested case-control study from the Japan Public Health Center-based prospective study group
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    J Clin Oncol 26:1677-83. 2008
    ..Nevertheless, no prospective study from Asia has assessed blood or urine levels as biomarkers of isoflavone intake...
  39. doi request reprint Serum aminotransferase level and the risk of hepatocellular carcinoma: a population-based cohort study in Japan
    Seiji Ishiguro
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 18:26-32. 2009
    ..This finding indicates that ALT level is a good independent determinant of the need for intervention. Clinical application of these findings may help decrease HCC-associated mortality in hepatitis virus-endemic regions...
  40. doi request reprint Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of colorectal cancer: a hospital-based case-control study in Japan
    Minatsu Kobayashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Scand J Gastroenterol 44:952-9. 2009
    ..A further objective was to investigate the possible effect of genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 on colorectal cancer...
  41. doi request reprint Methionine synthase A2756G polymorphism interacts with alcohol and folate intake to influence the risk of colorectal adenoma
    Taiki Yamaji
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Epidemiol Biomarkers Prev 18:267-74. 2009
    ..Our findings add to increasing evidence that DNA methylation plays an important role even at an early stage of colorectal carcinogenesis...
  42. doi request reprint Plasma tea polyphenol levels and subsequent risk of breast cancer among Japanese women: a nested case-control study
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Breast Cancer Res Treat 124:827-34. 2010
    ..This nested case-control study found no overall association between plasma tea polyphenols and the risk of breast cancer in Japan...
  43. doi request reprint Fish intake and type 2 diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study
    Akiko Nanri
    Department of Epidemiology and Prevention, International Clinical Research Center, National Center for Global Health and Medicine, Tokyo, Japan
    Am J Clin Nutr 94:884-91. 2011
    ..However, data from populations with high fish consumption are scarce...
  44. doi request reprint Leisure-time physical activity and breast cancer risk defined by estrogen and progesterone receptor status--the Japan Public Health Center-based Prospective Study
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo, 104 0045, Japan
    Prev Med 52:227-33. 2011
    ..The study aims to investigate the association between leisure-time physical activity and breast cancer risk in consideration of tumor estrogen-receptor/progesterone-receptor status...
  45. doi request reprint Plasma levels of C-reactive protein and serum amyloid A and gastric cancer in a nested case-control study: Japan Public Health Center-based prospective study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Carcinogenesis 31:712-8. 2010
    ..005). In conclusion, our results suggest that those who react strongly to inflammation or who have a high host immune response, as reflected by extremely elevated plasma levels of CRP and SAA, are at a high risk to develop gastric cancer...
  46. ncbi request reprint Colorectal cancer screening using fecal occult blood test and subsequent risk of colorectal cancer: a prospective cohort study in Japan
    Kyung Jae Lee
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Detect Prev 31:3-11. 2007
    ..To investigate prospectively the association between colorectal cancer screening and subsequent risk of colorectal cancer death in a large-scale population-based cohort study (the JPHC study) with a 13-year follow-up period in Japan...
  47. doi request reprint Effect of alcohol consumption, cigarette smoking and flushing response on esophageal cancer risk: a population-based cohort study (JPHC study)
    Seiji Ishiguro
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Lett 275:240-6. 2009
    ..10-5.51). Strong effect modification was detected in heavy smokers. Our results suggest that heavy alcohol consumption together with heavy smoking may increase the risk of ESCC particularly in individuals with the flushing response...
  48. doi request reprint Alcohol drinking and primary liver cancer: a pooled analysis of four Japanese cohort studies
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 130:2645-53. 2012
    ..0 g alcohol/day) in men and (2) moderate drinking (≥23.0 g alcohol/day) in women may reduce the risk of primary liver cancer...
  49. doi request reprint Reproductive factors, exogenous female hormone use and colorectal cancer risk: the Japan Public Health Center-based Prospective Study
    Munira Akhter
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 17:515-24. 2008
    ..59). In contrast, no statistically significant association was found for rectal cancer. These findings suggest that late age at first birth is associated with a reduced risk of colon cancer in postmenopausal Japanese women...
  50. ncbi request reprint Population attributable fraction of mortality associated with tobacco smoking in Japan: a pooled analysis of three large-scale cohort studies
    Kota Katanoda
    Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
    J Epidemiol 18:251-64. 2008
    ..We estimated the population attributable fraction (PAF) of mortality associated with smoking in Japan, using pooled data from three large-scale cohort studies...
  51. doi request reprint Leisure-time physical activity and breast cancer risk by hormone receptor status: effective life periods and exercise intensity
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tsukiji 5 1 1, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Causes Control 21:1787-98. 2010
    ..We investigated associations between age- and intensity-specific leisure-time physical activity and ER/PR-defined breast cancer risk...
  52. doi request reprint Projected cancer mortality among Japanese males under different smoking prevalence scenarios: evidence for tobacco control goal setting
    Kota Katanoda
    Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, 5 1 1 Tsukiji Chuo ku, Tokyo 104 0045, Japan
    Jpn J Clin Oncol 41:483-9. 2011
    ..The aim of the present study was to project cancer mortality among Japanese males under different future scenarios of smoking prevalence...
  53. doi request reprint Dietary calcium, vitamin D, and the risk of colorectal cancer
    Junko Ishihara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Clin Nutr 88:1576-83. 2008
    ..Calcium and vitamin D have a potential protective effect against colorectal cancer...
  54. doi request reprint Metabolic factors and subsequent risk of hepatocellular carcinoma by hepatitis virus infection status: a large-scale population-based cohort study of Japanese men and women (JPHC Study Cohort II)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Causes Control 20:741-50. 2009
    ..We prospectively examined whether metabolic factors predicts the subsequent risk of HCC in the Japan Public Health Center-based Prospective Study Cohort II, in consideration of hepatitis virus infection status...
  55. doi request reprint Coffee consumption and risk of endometrial cancer: a prospective study in Japan
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 123:2406-10. 2008
    ..Coffee consumption may be associated with a decreased risk of endometrial cancer...
  56. doi request reprint Fruit and vegetable consumption and squamous cell carcinoma of the esophagus in Japan: the JPHC study
    Taiki Yamaji
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 123:1935-40. 2008
    ..Finally, cruciferous vegetables deserve further investigation as foods possibly effective in the prevention of esophageal SCC...
  57. doi request reprint Association between polymorphisms in glutathione S-transferase Mu3 and IgG titer levels in serum against Helicobacter pylori
    Masayuki Tatemichi
    Department of Hygiene and Preventive Medicine, School of Medicine, Showa University, Shinagawa ku, Tokyo, Japan
    J Hum Genet 54:557-63. 2009
    ..pylori. GST-M3 activity is possibly involved in protection against mucosal atrophy caused by H. pylori as the levels of IgG titer and PGI are linked to mucosal status...
  58. ncbi request reprint Effect of Helicobacter pylori infection combined with CagA and pepsinogen status on gastric cancer development among Japanese men and women: a nested case-control study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 15:1341-7. 2006
    ..Possible effect modification by CagA status, and serum pepsinogen status, as a marker of atrophic gastritis, was also considered to see its effect on developing gastric cancer. Subjects and..
  59. ncbi request reprint Atrophic gastritis, Helicobacter pylori, and colorectal cancer risk: a case-control study
    Ai Machida-Montani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Helicobacter 12:328-32. 2007
    ..However, the correlation between H. pylori and colorectal cancer (CRC) is controversial. The aim of this study was to examine the correlation between H. pylori, serum gastrin level, and atrophic gastritis with CRC...
  60. ncbi request reprint Effect of soy isoflavones on endometriosis: interaction with estrogen receptor 2 gene polymorphism
    Masaki Tsuchiya
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Epidemiology 18:402-8. 2007
    ..We examined associations among soy isoflavone intake, estrogen receptor 2 (ESR2) gene polymorphisms and risk of endometriosis...
  61. ncbi request reprint Comparisons between anthropometric indices for predicting the metabolic syndrome in Japanese
    Masayuki Kato
    Japan Foundation for the Promotion of International Medical Research Cooperation, Tokyo, Japan
    Asia Pac J Clin Nutr 17:223-8. 2008
    ....
  62. ncbi request reprint Coffee consumption and risk of colorectal cancer in a population-based prospective cohort of Japanese men and women
    Kyung Jae Lee
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 121:1312-8. 2007
    ..These findings suggest that coffee consumption may lower the risk of colon cancer among Japanese women...
  63. pmc Adult mortality attributable to preventable risk factors for non-communicable diseases and injuries in Japan: a comparative risk assessment
    Nayu Ikeda
    Department of Global Health Policy, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    PLoS Med 9:e1001160. 2012
    ..We estimated the effects of 16 risk factors on cause-specific deaths and life expectancy in Japan...
  64. doi request reprint Association of weight change in different periods of adulthood with risk of type 2 diabetes in Japanese men and women: the Japan Public Health Center-Based Prospective Study
    Akiko Nanri
    Department of Epidemiology and International Health, Research Institute, International Medical Center of Japan, Toyama 1 21 1, Shinjuku ku, Tokyo, Japan
    J Epidemiol Community Health 65:1104-10. 2011
    ..We prospectively investigated the association of weight change since age 20 y and that during middle-to-late adulthood with the incidence of type 2 diabetes...
  65. ncbi request reprint Body mass index and mortality from all causes and major causes in Japanese: results of a pooled analysis of 7 large-scale cohort studies
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Epidemiol 21:417-30. 2011
    ....
  66. doi request reprint Visceral fat volume and the prevalence of colorectal adenoma
    Taiki Yamaji
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Epidemiol 170:1502-11. 2009
    ..The mechanisms of this potential association between visceral adiposity and colorectal carcinogenesis warrant further investigation...
  67. doi request reprint Consumption of sodium and salted foods in relation to cancer and cardiovascular disease: the Japan Public Health Center-based Prospective Study
    Ribeka Takachi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Clin Nutr 91:456-64. 2010
    ....
  68. doi request reprint Clinical significance of IgG antibody titer against Helicobacter pylori
    Masayuki Tatemichi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Helicobacter 14:231-6. 2009
    ..We clarified the clinical significance of measurement of IgG antibody titers against Helicobacter pylori using data from a nested case-control study from a large-scale cohort study in Japan...
  69. doi request reprint Impact of viral load of hepatitis C on the incidence of hepatocellular carcinoma: A population-based cohort study (JPHC Study)
    Seiji Ishiguro
    National Cancer Center, Tokyo, Japan
    Cancer Lett 300:173-9. 2011
    ..The risk was 3.86-fold higher (CI; 1.73-8.62) for genotype 1 than genotype 2. Our findings suggest that HCV viremia strongly influences the occurrence of hepatocellular carcinoma without titer-dependence...
  70. doi request reprint Plasma isoflavones and the risk of lung cancer in women: a nested case-control study in Japan
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, 104 0045 Japan
    Cancer Epidemiol Biomarkers Prev 20:419-27. 2011
    ....
  71. doi request reprint Effect of coffee and green tea consumption on the risk of liver cancer: cohort analysis by hepatitis virus infection status
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 18:1746-53. 2009
    ..Our results suggest that coffee consumption may reduce the risk of liver cancer regardless of HCV and HBV infection status, whereas green tea may not reduce this risk..
  72. doi request reprint High dietary intake of magnesium may decrease risk of colorectal cancer in Japanese men
    Enbo Ma
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Nutr 140:779-85. 2010
    ..There were no significant associations between magnesium intake and cancer risk in women. Higher dietary intake of magnesium may decrease the risk of CRC in Japanese men...
  73. ncbi request reprint Fasting plasma glucose and 5-year incidence of diabetes in the JPHC diabetes study - suggestion for the threshold for impaired fasting glucose among Japanese
    Mitsuhiko Noda
    Department of Diabetes and Metabolic Medicine, National Center for Global Health and Medicine, Shinjuku ku, Tokyo, Japan
    Endocr J 57:629-37. 2010
    ..The results of this study suggested that the cut-off FPG value should be lowered in terms of prediction of type 2 diabetes among Japanese populations...
  74. doi request reprint Plasma testosterone and sex hormone-binding globulin concentrations and the risk of prostate cancer among Japanese men: a nested case-control study
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Sci 101:2652-7. 2010
    ..In conclusion, in this nested case-control study, concentrations of circulating total testosterone, free testosterone or SHBG were not strongly associated with a risk for total prostate cancer...
  75. doi request reprint Validity of self-reported cancer among a Japanese population: recent results from a population-based prospective study in Japan (JPHC Study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol 35:250-3. 2011
    ..Self-reported diagnoses of cancer do not provide sufficient accuracy for the detection and classification of incident cancers. Our findings may be extrapolated to other Japanese populations...
  76. doi request reprint Alcohol consumption-associated breast cancer incidence and potential effect modifiers: the Japan Public Health Center-based Prospective Study
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Int J Cancer 127:685-95. 2010
    ..15). Excessive alcohol intake was associated with an increase in the risk of breast cancer in this population. There was no statistical evidence for effect modification...
  77. ncbi request reprint Passive smoking and lung cancer in Japanese non-smoking women: a prospective study
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji Chuo ku, Tokyo, Japan
    Int J Cancer 122:653-7. 2008
    ..93, 95% CI 0.88-4.23). These findings confirm that passive smoking is a risk factor for lung cancer, especially for adenocarcinoma among Japanese women...
  78. ncbi request reprint Patterns of alcohol drinking and all-cause mortality: results from a large-scale population-based cohort study in Japan
    Tomomi Marugame
    Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
    Am J Epidemiol 165:1039-46. 2007
    ..These findings support the Japanese social belief that "liver holidays," abstaining from alcohol for more than 2 days per week, are important for heavy drinkers...
  79. doi request reprint Alcohol drinking and colorectal cancer in Japanese: a pooled analysis of results from five cohort studies
    Tetsuya Mizoue
    Department of Epidemiology and International Health, Research Institute, International Medical Center of Japan, Tokyo, Japan
    Am J Epidemiol 167:1397-406. 2008
    ..An alcohol-colorectal cancer association seems to be more apparent in Japanese than in Western populations. Whether this difference can be ascribed to genetic or environmental factors needs to be clarified...
  80. ncbi request reprint Physical activity and risk of colorectal cancer in Japanese men and women: the Japan Public Health Center-based prospective study
    Kyung Jae Lee
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo, Japan
    Cancer Causes Control 18:199-209. 2007
    ....
  81. ncbi request reprint Generalizability of relative risk estimates from a well-defined population to a general population
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Eur J Epidemiol 21:253-62. 2006
    ..06). Our results suggest that even for RRs, the extrapolation of estimates for a sample from a well-defined population to a general population may not be possible...
  82. doi request reprint Dietary soy and isoflavone intake and risk of colorectal cancer in the Japan public health center-based prospective study
    Munira Akhter
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Epidemiol Biomarkers Prev 17:2128-35. 2008
    ..These findings suggest that the intake of isoflavones, miso soup, and soy food has no substantial effect on the risk of colorectal cancer in Japanese men and women...
  83. doi request reprint Impact of metabolic factors on subsequent cancer risk: results from a large-scale population-based cohort study in Japan
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, International Medical Center of Japan, Tokyo, Japan
    Eur J Cancer Prev 18:240-7. 2009
    ..21-2.55). Metabolic factors in the aggregate may have little impact on total cancer risk in the Japanese population, although the association between specific components and specific cancers suggests an etiologic link between them...
  84. ncbi request reprint hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gastric cancer risk in Japanese populations
    Hiromasa Tsukino
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Cancer Sci 95:977-83. 2004
    ..The results of the present study suggest that patients with atrophic gastritis in conjunction with the hOGG1 Cys allele might have a higher susceptibility to gastric cancer...
  85. doi request reprint Different etiological role of Helicobacter pylori (Hp) infection in carcinogenesis between differentiated and undifferentiated gastric cancers: a nested case-control study using IgG titer against Hp surface antigen
    Masayuki Tatemichi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Acta Oncol 47:360-5. 2008
    ....
  86. ncbi request reprint Soy product and isoflavone consumption in relation to prostate cancer in Japanese men
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo 104 0045 Japan
    Cancer Epidemiol Biomarkers Prev 16:538-45. 2007
    ..52 [95% confidence interval (95% CI), 0.30-0.90], 0.50 (95% CI, 0.28-0.88), and 0.52 (95% CI, 0.29-0.90), respectively. In conclusion, we found that isoflavone intake was associated with a decreased risk of localized prostate cancer...
  87. ncbi request reprint Prospective study showing that dietary vitamin C reduced the risk of age-related cataracts in a middle-aged Japanese population
    Masao Yoshida
    Dept of Public Health, Kyorin University School of Medicine, Tokyo, Japan
    Eur J Nutr 46:118-24. 2007
    ....
  88. ncbi request reprint Serum triglycerides and colorectal adenoma in a case-control study among cancer screening examinees (Japan)
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Causes Control 17:1245-52. 2006
    ..However, whether the association can be modified by smoking is unknown. We cross-sectionally investigated the association of serum triglycerides with the risk of adenoma by smoking status...
  89. ncbi request reprint [Dietary factor and cancer risk--evidence from epidemiological studies]
    Shoichiro Tsugane
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuoku, Tokyo 104 0045, Japan
    Gan To Kagaku Ryoho 31:847-52. 2004
    ....
  90. ncbi request reprint Psychological factors, coffee and risk of diabetes mellitus among middle-aged Japanese: a population-based prospective study in the JPHC study cohort
    Masayuki Kato
    Japan Foundation for Promotion of International Medical Research Cooperation, Tokyo, Japan
    Endocr J 56:459-68. 2009
    ..In addition, inverse association between coffee consumption and the incidence of diabetes which was consistent with other studies was observed...
  91. ncbi request reprint Prospective study of three major dietary patterns and risk of gastric cancer in Japan
    Mi Kyung Kim
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 110:435-42. 2004
    ..These associations persisted in histologic subtypes. Our findings support the idea that the healthy pattern decreased the risk of gastric cancer among females, while the traditional pattern increased the risk in both genders...
  92. ncbi request reprint Impact of the revision of a nutrient database on the validity of a self-administered food frequency questionnaire (FFQ)
    Junko Ishihara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Epidemiol 16:107-16. 2006
    ..Here, we investigated the effect of this revision of the nutrient database on the validity of a food frequency questionnaire (FFQ) used to estimate nutrient intake in the Japan Public Health Center-based prospective Study (JPHC Study)...
  93. ncbi request reprint Vegetables, fruit consumption and risk of lung cancer among middle-aged Japanese men and women: JPHC study
    Ying Liu
    Statistics and Cancer Control Division, National Cancer Center, Tokyo, Japan
    Cancer Causes Control 15:349-57. 2004
    ..To investigate the association between vegetable and fruit consumption and incidence of lung cancer...
  94. ncbi request reprint Blood pressure change in a free-living population-based dietary modification study in Japan
    Yoshiko Takahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention, Tokyo, Japan
    J Hypertens 24:451-8. 2006
    ..To assess whether dietary intervention in free-living healthy subjects is effective in improving blood pressure levels...
  95. ncbi request reprint Body mass index, physical activity and the risk of pancreatic cancer in relation to smoking status and history of diabetes: a large-scale population-based cohort study in Japan--the JPHC study
    Juhua Luo
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Cancer Causes Control 18:603-12. 2007
    ..In particular, we explored how these effects were influenced by smoking status and a history of diabetes...
  96. ncbi request reprint Low intake of vitamin B-6 is associated with increased risk of colorectal cancer in Japanese men
    Junko Ishihara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    J Nutr 137:1808-14. 2007
    ..Our results support previous evidence that low vitamin B-6 intake is associated with an increased risk of colorectal cancer. In particular, a higher intake of vitamin B-6 appears beneficial in men with higher alcohol intake...
  97. ncbi request reprint Plasma folate and risk of colorectal cancer in a nested case-control study: the Japan Public Health Center-based prospective study
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer Causes Control 19:67-74. 2008
    ..We investigated the association between plasma folate and the risk of colorectal cancer in a nested case-control study...
  98. ncbi request reprint Fish, long-chain n-3 polyunsaturated fatty acids, and risk of colorectal cancer in middle-aged Japanese: the JPHC study
    Minatsu Kobayashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Nutr Cancer 49:32-40. 2004
    ..This study does not support the role of fish and Ln-3 PUFA in the etiology of colon and rectal cancer in this population whose fish consumption was high and the variation in Ln-3 PUFA consumption was large...
  99. pmc Plasma organochlorines and subsequent risk of prostate cancer in Japanese men: a nested case-control study
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Environ Health Perspect 118:659-65. 2010
    ..To our knowledge, this is the first prospective study to investigate the association between blood levels of organochlorines and prostate cancer risk...
  100. ncbi request reprint Reproductive factors, hormone use and the risk of lung cancer among middle-aged never-smoking Japanese women: a large-scale population-based cohort study
    Ying Liu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 117:662-6. 2005
    ..40 (95% CI 1.07-5.40). These findings suggest that both endogenous and extraneous estrogen may be involved in the etiology of lung cancer...
  101. doi request reprint Alcohol drinking and gastric cancer risk: an evaluation based on a systematic review of epidemiologic evidence among the Japanese population
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Jpn J Clin Oncol 38:8-25. 2008
    ..This report is one of a series of articles by our research group, which is evaluating the existing evidence concerning the association between health-related lifestyles and cancer...