S Tsugane

Summary

Affiliation: National Cancer Center
Country: Japan

Publications

  1. ncbi request reprint Under- and overweight impact on mortality among middle-aged Japanese men and women: a 10-y follow-up of JPHC study cohort I
    S Tsugane
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Japan
    Int J Obes Relat Metab Disord 26:529-37. 2002
  2. ncbi request reprint Smoking and risk of premature death among middle-aged Japanese: ten-year follow-up of the Japan Public Health Center-based prospective study on cancer and cardiovascular diseases (JPHC Study) cohort I
    Megumi Hara
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba 277 8577, Japan
    Jpn J Cancer Res 93:6-14. 2002
  3. ncbi request reprint Four food-frequency categories of fruit intake as a predictor of plasma ascorbic acid level in middle-aged Japanese men
    S Tsugane
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba, Japan
    Ann Epidemiol 8:378-83. 1998
  4. pmc Salt and salted food intake and subsequent risk of gastric cancer among middle-aged Japanese men and women
    S Tsugane
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, 6 5 1 Kashiwanoha, Kashiwa, 277 8577, Japan
    Br J Cancer 90:128-34. 2004
  5. ncbi request reprint Effect of five-year supplementation of vitamin C on serum vitamin C concentration and consumption of vegetables and fruits in middle-aged Japanese: a randomized controlled trial
    Mi Kyung Kim
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Chiba, Japan
    J Am Coll Nutr 22:208-16. 2003
  6. ncbi request reprint Serological Immunoglobulin G antibody titers to Helicobacter pylori in Japanese Brazilian and Non-Japanese Brazilian gastric cancer patients and controls in São Paulo
    N Fujioka
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba 277 8577, Japan
    Jpn J Cancer Res 92:829-35. 2001
  7. ncbi request reprint Nutrient consumption and gastric cancer mortality in five regions of Japan
    Y Tsubono
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Japan
    Nutr Cancer 27:310-5. 1997
  8. ncbi request reprint Effects of three-month oral supplementation of beta-carotene and vitamin C on serum concentrations of carotenoids and vitamins in middle-aged subjects: a pilot study for a randomized controlled trial to prevent gastric cancer in high-risk Japanese populat
    S Sasaki
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, 6 5 1 Kashiwanoha, Kashiwa 277 8577, Japan
    Jpn J Cancer Res 91:464-70. 2000
  9. ncbi request reprint Dietary habits among the JPHC study participants at baseline survey. Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases
    S Tsugane
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba, Japan
    J Epidemiol 11:S30-43. 2001
  10. ncbi request reprint Single measurement of serum phospholipid fatty acid as a biomarker of specific fatty acid intake in middle-aged Japanese men
    M Kobayashi
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba, Japan
    Eur J Clin Nutr 55:643-50. 2001

Collaborators

Detail Information

Publications107 found, 100 shown here

  1. ncbi request reprint Under- and overweight impact on mortality among middle-aged Japanese men and women: a 10-y follow-up of JPHC study cohort I
    S Tsugane
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Japan
    Int J Obes Relat Metab Disord 26:529-37. 2002
    ..This paper examines the association between body mass index (BMI; kg/m2) and mortality in Japan, where the mortality profile and BMI distribution differ substantially from Western countries...
  2. ncbi request reprint Smoking and risk of premature death among middle-aged Japanese: ten-year follow-up of the Japan Public Health Center-based prospective study on cancer and cardiovascular diseases (JPHC Study) cohort I
    Megumi Hara
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba 277 8577, Japan
    Jpn J Cancer Res 93:6-14. 2002
    ..These findings provided information as to the quantitative risk for premature death due to smoking among middle-aged Japanese men and women, and showed that the elevated risk was not explained by the unhealthy lifestyle of smokers...
  3. ncbi request reprint Four food-frequency categories of fruit intake as a predictor of plasma ascorbic acid level in middle-aged Japanese men
    S Tsugane
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba, Japan
    Ann Epidemiol 8:378-83. 1998
    ..To assess the predictability of plasma ascorbic acid level in Japanese men, we examined its association with dietary sources of vitamin C and other lifestyle factors...
  4. pmc Salt and salted food intake and subsequent risk of gastric cancer among middle-aged Japanese men and women
    S Tsugane
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, 6 5 1 Kashiwanoha, Kashiwa, 277 8577, Japan
    Br J Cancer 90:128-34. 2004
    ..Restriction of salt and salted food intake is a practical strategy to prevent gastric cancer in areas with high risk...
  5. ncbi request reprint Effect of five-year supplementation of vitamin C on serum vitamin C concentration and consumption of vegetables and fruits in middle-aged Japanese: a randomized controlled trial
    Mi Kyung Kim
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Chiba, Japan
    J Am Coll Nutr 22:208-16. 2003
    ..This study was aimed at evaluating the effect of long-term vitamin C supplementation on serum and dietary vitamin C and identifying the factors associated with change in serum concentration...
  6. ncbi request reprint Serological Immunoglobulin G antibody titers to Helicobacter pylori in Japanese Brazilian and Non-Japanese Brazilian gastric cancer patients and controls in São Paulo
    N Fujioka
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba 277 8577, Japan
    Jpn J Cancer Res 92:829-35. 2001
    ..pylori from the stomach...
  7. ncbi request reprint Nutrient consumption and gastric cancer mortality in five regions of Japan
    Y Tsubono
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Japan
    Nutr Cancer 27:310-5. 1997
    ..The results suggest that variation in gastric cancer mortality in Japan may be partly accounted for by the regional differences in consumption of sodium, carotene, and possibly ascorbic acid...
  8. ncbi request reprint Effects of three-month oral supplementation of beta-carotene and vitamin C on serum concentrations of carotenoids and vitamins in middle-aged subjects: a pilot study for a randomized controlled trial to prevent gastric cancer in high-risk Japanese populat
    S Sasaki
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, 6 5 1 Kashiwanoha, Kashiwa 277 8577, Japan
    Jpn J Cancer Res 91:464-70. 2000
    ..No unfavorable change in carotenoids and alpha-tocopherol was observed in any group...
  9. ncbi request reprint Dietary habits among the JPHC study participants at baseline survey. Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases
    S Tsugane
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba, Japan
    J Epidemiol 11:S30-43. 2001
    ..Cooking methods for meats, seafoods and vegetables were also unique in Okinawa. No distinct geographical difference was shown in food preference and modification of dietary habit by dietary advice...
  10. ncbi request reprint Single measurement of serum phospholipid fatty acid as a biomarker of specific fatty acid intake in middle-aged Japanese men
    M Kobayashi
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba, Japan
    Eur J Clin Nutr 55:643-50. 2001
    ..CONCLUSIONS: These data suggest that in populations with a high and stable over time intake of n-3 PUFA of marine origin, a single measurement of serum phospholipids reflects the ranking of habitual intake of marine origin n-3 PUFA...
  11. ncbi request reprint Within- and between-person variations in portion sizes of foods consumed by the Japanese population
    Y Tsubono
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Japan
    Nutr Cancer 29:140-5. 1997
    ....
  12. ncbi request reprint Effect of smoking on the association between alcohol consumption and cancer mortality among middle-aged Japanese men: JPHC Study Cohort I
    M Hara
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Chiba, Japan
    IARC Sci Publ 156:165-8. 2002
  13. ncbi request reprint Plasma antioxidant vitamins and carotenoids in five Japanese populations with varied mortality from gastric cancer
    Y Tsubono
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Japan
    Nutr Cancer 34:56-61. 1999
    ..The results suggest that plasma levels of beta-carotene and alpha-tocopherol, and possibly alpha-carotene, lycopene, and ascorbic acid, may partly account for the regional difference in gastric cancer mortality in Japan...
  14. ncbi request reprint Food composition and empirical weight methods in predicting nutrient intakes from food frequency questionnaire
    Y Tsubono
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Japan
    Ann Epidemiol 11:213-8. 2001
    ..62) for women in the former method, and 0.26 (-0.04-0.58) for men and 0.38 (0.18-0.67) for women in the latter method. CONCLUSIONS: We did not find the improved validity of FFQ by empirical weight method in predicting nutrient intakes...
  15. ncbi request reprint Residuals of beta-hexachlorocyclohexane, dichlorodiphenyltrichloroethane, and hexachlorobenzene in serum, and relations with consumption of dietary components in rural residents in Japan
    T Hanaoka
    Epidemioloy and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa shi, Chiba, Japan
    Sci Total Environ 286:119-27. 2002
    ..The present study suggests that organochlorine compounds are transported into the human body via foods in the Japanese population. Their effects on health should thus be investigated and monitored...
  16. pmc Daily omega-3 fatty acid intake and depression in Japanese patients with newly diagnosed lung cancer
    S Suzuki
    Psycho Oncology Division, National Cancer Center Research Institute East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    Br J Cancer 90:787-93. 2004
    ....
  17. ncbi request reprint Development of substituted fatty acid food composition table for the use in nutritional epidemiologic studies for Japanese populations: its methodological backgrounds and the evaluation
    S Sasaki
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute, Chiba, Japan
    J Epidemiol 9:190-207. 1999
    ..01 in men and from 1.13 to 0.96 in women. The use of the developed fatty acid food composition table may increase the reliability on nutrition-disease association in future nutritional epidemiologic studies for Japanese populations...
  18. ncbi request reprint Baseline survey of JPHC study--design and participation rate. Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases
    S Tsugane
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba, Japan
    J Epidemiol 11:S24-9. 2001
    ..These data and blood samples serve as basis for the Japan Public Health Center-based prospective Study on cancer and cardiovascular diseases (JPHC Study)...
  19. ncbi request reprint hOGG1 exon7 polymorphism and gastric cancer in case-control studies of Japanese Brazilians and non-Japanese Brazilians
    T Hanaoka
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, 6 5 1 Kashinoha, Kashiwa shi, 277 8577, Chiba, Japan
    Cancer Lett 170:53-61. 2001
    ..The ethnic difference in hOGG1 Ser326Cys polymorphism was much greater than the case-control difference, and this polymorphism is unlikely to be associated with gastric cancer...
  20. ncbi request reprint Sensitivity of self-reports of cancer in a population-based prospective study: JPHC Study Cohort I
    A Yoshinaga
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, 6-5-1 Kashiwanoha, Kashiwa 277-8577, Japan
    J Clin Epidemiol 54:741-6. 2001
    ..In conclusion, the sensitivity of self-reports of cancer was much lower in this cohort than in the US results except for breast cancer...
  21. doi request reprint Plasma testosterone and sex hormone-binding globulin concentrations and the risk of prostate cancer among Japanese men: a nested case-control study
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Sci 101:2652-7. 2010
    ..In conclusion, in this nested case-control study, concentrations of circulating total testosterone, free testosterone or SHBG were not strongly associated with a risk for total prostate cancer...
  22. doi request reprint Daily total physical activity level and total cancer risk in men and women: results from a large-scale population-based cohort study in Japan
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Epidemiol 168:391-403. 2008
    ..By site, decreased risks were observed for cancers of the colon, liver, and pancreas in men and for cancer of the stomach in women. Increased daily physical activity may be beneficial in preventing cancer in a relatively lean population...
  23. doi request reprint Plasma organochlorine levels and subsequent risk of breast cancer among Japanese women: a nested case-control study
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Sci Total Environ 402:176-83. 2008
    ..Our data do not support the hypothesis that plasma levels of p,p'-DDT, p,p'-DDE, HCB, and beta-HCH are associated with an overall increased risk of breast cancer among Japanese women...
  24. doi request reprint Daily total physical activity level and premature death in men and women: results from a large-scale population-based cohort study in Japan (JPHC study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 18:522-30. 2008
    ..We prospectively examined the association between daily total physical activity level (METs/day) and subsequent risk of all-cause mortality and mortalities from cancer, heart disease, and cerebrovascular disease...
  25. doi request reprint Alcohol and risk of lung cancer among Japanese men: data from a large-scale population-based cohort study, the JPHC study
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Causes Control 19:1095-102. 2008
    ..Here, we investigated the association between alcohol consumption and lung cancer incidence...
  26. ncbi request reprint Impact of lifestyle on overall cancer risk among Japanese: the Japan Public Health Center-based Prospective Study (JPHC Study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Epidemiol 20:90-6. 2010
    ..Although people with a history of diabetes may be at increased risk of cancer, extreme body mass index and metabolic factors in the aggregate had little impact on overall cancer risk in the Japanese population...
  27. pmc Use of vitamin supplements and risk of total cancer and cardiovascular disease among the Japanese general population: a population-based survey
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo 104 0045, Japan
    BMC Public Health 11:540. 2011
    ..We examined whether vitamin supplement use patterns affect cancer and CVD risk in a population-based cohort study in Japan...
  28. ncbi request reprint Effect of vitamin C on common cold: randomized controlled trial
    S Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Eur J Clin Nutr 60:9-17. 2006
    ..To investigate the relationship between the common cold and vitamin C supplementation...
  29. doi request reprint Plasma isoflavones and the risk of lung cancer in women: a nested case-control study in Japan
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, 104 0045 Japan
    Cancer Epidemiol Biomarkers Prev 20:419-27. 2011
    ....
  30. pmc Epidemiology of gastric cancer in Japan
    M Inoue
    Epidemiology and Prevention Division, Research Centre for Cancer Prevention and Screening, National Cancer Centre, 5 1 1 Tsukiji, Tokyo 104 0045, Japan
    Postgrad Med J 81:419-24. 2005
    ....
  31. doi request reprint Fruit and vegetable consumption and squamous cell carcinoma of the esophagus in Japan: the JPHC study
    Taiki Yamaji
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 123:1935-40. 2008
    ..Finally, cruciferous vegetables deserve further investigation as foods possibly effective in the prevention of esophageal SCC...
  32. doi request reprint Coffee, green tea, and caffeine consumption and subsequent risk of bladder cancer in relation to smoking status: a prospective study in Japan
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer Sci 100:294-91. 2009
    ..15–3.66), respectively. In conclusion, cigarette smoking was confirmed as a risk factor for bladder cancer. Coffee and caffeine may be associated with an increased bladder cancer risk in never or former smokers among Japanese men...
  33. doi request reprint Intake of n-3 and n-6 polyunsaturated fatty acids and development of colorectal cancer by subsite: Japan Public Health Center-based prospective study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 129:1718-29. 2011
    ..Our results suggest that intake of marine n-3 polyunsaturated fatty acids may be inversely related to the risk of cancer in the proximal site of the large bowel...
  34. doi request reprint Body mass index and subsequent risk of kidney cancer: a prospective cohort study in Japan
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 20:466-72. 2010
    ..Herein, we investigate the association between body mass index (BMI) and kidney cancer risk in Japanese persons, a relatively lean population...
  35. doi request reprint Validity of self-reported cancer among a Japanese population: recent results from a population-based prospective study in Japan (JPHC Study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol 35:250-3. 2011
    ..Self-reported diagnoses of cancer do not provide sufficient accuracy for the detection and classification of incident cancers. Our findings may be extrapolated to other Japanese populations...
  36. doi request reprint Plasma levels of C-reactive protein and serum amyloid A and gastric cancer in a nested case-control study: Japan Public Health Center-based prospective study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Carcinogenesis 31:712-8. 2010
    ..005). In conclusion, our results suggest that those who react strongly to inflammation or who have a high host immune response, as reflected by extremely elevated plasma levels of CRP and SAA, are at a high risk to develop gastric cancer...
  37. doi request reprint Isoflavone intake and risk of lung cancer: a prospective cohort study in Japan
    Taichi Shimazu
    Research Center for Cancer Prevention and Screening, National Cancer Center Tokyo Japan
    Am J Clin Nutr 91:722-8. 2010
    ..Moreover, no prospective study has addressed this association in men...
  38. doi request reprint Effect of coffee and green tea consumption on the risk of liver cancer: cohort analysis by hepatitis virus infection status
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 18:1746-53. 2009
    ..Our results suggest that coffee consumption may reduce the risk of liver cancer regardless of HCV and HBV infection status, whereas green tea may not reduce this risk..
  39. doi request reprint Green tea consumption and gastric cancer in Japanese: a pooled analysis of six cohort studies
    M Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045 Japan
    Gut 58:1323-32. 2009
    ..Previous experimental studies have suggested many possible anti-cancer mechanisms for green tea, but epidemiological evidence for the effect of green tea consumption on gastric cancer risk is conflicting...
  40. pmc Vegetable, fruit and antioxidant nutrient consumption and subsequent risk of hepatocellular carcinoma: a prospective cohort study in Japan
    N Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center 5 1 1, Tsukiji Chuo ku, Tokyo 104 0045, Japan
    Br J Cancer 100:181-4. 2009
    ..61 (95% confidence interval (CI)=0.36-1.03, P(trend)=0.07), 0.65 (95% CI=0.39-1.08, P(trend)=0.06) and 0.59 (95% CI=0.35-1.01, P(trend)=0.04), respectively...
  41. doi request reprint Metabolic factors and subsequent risk of hepatocellular carcinoma by hepatitis virus infection status: a large-scale population-based cohort study of Japanese men and women (JPHC Study Cohort II)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Causes Control 20:741-50. 2009
    ..We prospectively examined whether metabolic factors predicts the subsequent risk of HCC in the Japan Public Health Center-based Prospective Study Cohort II, in consideration of hepatitis virus infection status...
  42. doi request reprint Isoflavone consumption and subsequent risk of hepatocellular carcinoma in a population-based prospective cohort of Japanese men and women
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 124:1644-9. 2009
    ..Women with hepatitis virus infection may be advised to abstain from isoflavone consumption. Further studies are warranted to confirm these findings...
  43. doi request reprint Dairy product, saturated fatty acid, and calcium intake and prostate cancer in a prospective cohort of Japanese men
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 17:930-7. 2008
    ..62 (1.15-2.29) and 1.53 (1.07-2.20), respectively. In conclusion, our results suggest that the intake of dairy products may be associated with an increased risk of prostate cancer...
  44. ncbi request reprint Association between smoking and tumor progression in Japanese women with adenocarcinoma of the lung
    I Sekine
    Division of Internal Medicine and Thoracic Oncology, National Cancer Center Hospital, Tokyo
    Jpn J Cancer Res 90:129-35. 1999
    ..This association was not observed in women with non-adenocarcinoma and was weaker in men, suggesting various effects of smoking on lung cancer development depending on gender and the histological type of the tumor...
  45. ncbi request reprint Validity and reproducibility of a self-administered food-frequency questionnaire to assess isoflavone intake in a japanese population in comparison with dietary records and blood and urine isoflavones
    S Yamamoto
    National Cancer Center Research Institute, Tokyo and Kashiwa, Japan Tokyo University of Agriculture, Tokyo, Japan
    J Nutr 131:2741-7. 2001
    ..The original FFQ and the shorter versions have sufficient validity and reproducibility to be used in epidemiologic studies...
  46. ncbi request reprint Study design and organization of the JPHC study. Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases
    S Watanabe
    National Cancer Center Research Institute East, Kashiwa, Chiba, Japan
    J Epidemiol 11:S3-7. 2001
    ..The JPHC study is expected to provide evidence for the prevention and control of cancer and cardiovascular diseases in the 21st century...
  47. ncbi request reprint Development and validation of specific carotene food composition tables for use in nutritional epidemiologic studies for Japanese populations
    Y Takahashi
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa-city, Chiba, Japan
    J Epidemiol 11:266-75. 2001
    ..The similar correlations with the serum concentrations may indicate an comparable value for ranking individuals between the two tables. However, the results were inconclusive for the estimation of absolute intakes...
  48. pmc Urinary bisphenol A and plasma hormone concentrations in male workers exposed to bisphenol A diglycidyl ether and mixed organic solvents
    T Hanaoka
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, 6 5 1 Kashiwanoha, Chiba 277 8577, Japan
    Occup Environ Med 59:625-8. 2002
    ..To evaluate effects of exposure to bisphenol A diglycidyl ether (BADGE) on urinary excretion of bisphenol A, and plasma gonadotrophic hormones and testosterone in male epoxy resin sprayers...
  49. ncbi request reprint Chip ligating human genomic DNA serves as storage material and template for polymerase chain reaction
    T Hanaoka
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Chiba, Japan
    Biotechnol Lett 25:509-12. 2003
    ..Moreover, a chip fixing two restriction sites (e.g. EcoRI and HindIII) showed the amplification by PCR for any location of genomic DNA. Repetitive PCRs have confirmed that a DNA chip can be stored by at -4 degrees C for 2 years...
  50. ncbi request reprint Intake of folate, vitamin B6 and vitamin B12 and the risk of CHD: the Japan Public Health Center-Based Prospective Study Cohort I
    Junko Ishihara
    Department of Public Health Medicine, University of Tsukuba, Ibaraki, Japan
    J Am Coll Nutr 27:127-36. 2008
    ..To investigate the association of dietary folate, vitamin B(6) (VB(6)) and vitamin B(12) (VB(12)) with the risk of coronary heart disease among middle-aged persons...
  51. ncbi request reprint Reduced life expectancy due to smoking in large-scale cohort studies in Japan
    Kotaro Ozasa
    Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kamigyo ku, Kyoto 602 8566, Japan
    J Epidemiol 18:111-8. 2008
    ..To show the reduction in life expectancy due to smoking and the recovery of normal life expectancy by smoking cessation is useful for tobacco control health policy...
  52. ncbi request reprint Background characteristics of basic health examination participants: the JPHC Study Baseline Survey
    Motoki Iwasaki
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    J Epidemiol 13:216-25. 2003
    ..The aim of this study is to clarify the background characteristics of participants and to discuss their impact on epidemiologic studies...
  53. doi request reprint Plasma levels of carotenoids, retinol and tocopherol and the risk of gastric cancer in Japan: a nested case-control study
    Christina Persson
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo ku 104 0045, Tokyo, Japan
    Carcinogenesis 29:1042-8. 2008
    ..Our findings suggest that those who have very low plasma levels of alpha-carotene and beta-carotene are at a higher risk of gastric cancer...
  54. ncbi request reprint A population-based dietary intervention trial in a high-risk area for stomach cancer and stroke: changes in intakes and related biomarkers
    Yoshiko Takashashi
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Japan
    Prev Med 37:432-41. 2003
    ..The Hiraka Dietary Intervention Study is a community-based randomized cross-over trial designed to develop an effective dietary modification tool and system in an area with high mortality of stomach cancer and stroke...
  55. doi request reprint Different etiological role of Helicobacter pylori (Hp) infection in carcinogenesis between differentiated and undifferentiated gastric cancers: a nested case-control study using IgG titer against Hp surface antigen
    Masayuki Tatemichi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Acta Oncol 47:360-5. 2008
    ....
  56. ncbi request reprint Cruciferous vegetables, mushrooms, and gastrointestinal cancer risks in a multicenter, hospital-based case-control study in Japan
    Megumi Hara
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Chiba, Japan
    Nutr Cancer 46:138-47. 2003
    ..These findings suggest that cruciferous vegetables decrease the risk of both stomach and colorectal cancer, and that mushrooms are associated with a decreased risk of stomach cancer...
  57. ncbi request reprint Association of dietary intake of soy, beans, and isoflavones with risk of cerebral and myocardial infarctions in Japanese populations: the Japan Public Health Center-based (JPHC) study cohort I
    Yoshihiro Kokubo
    Department of Preventive Cardiology, National Cardiovascular Center, 5 7 1, Fujishiro dai, Suita, Osaka, 565 8565 Japan
    Circulation 116:2553-62. 2007
    ..We investigated the association of soy and isoflavone intake with risk of cerebral and myocardial infarctions (CI and MI)...
  58. ncbi request reprint Plasma folate and risk of colorectal cancer in a nested case-control study: the Japan Public Health Center-based prospective study
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer Causes Control 19:67-74. 2008
    ..We investigated the association between plasma folate and the risk of colorectal cancer in a nested case-control study...
  59. ncbi request reprint Fruit and vegetable intake and risk of total cancer and cardiovascular disease: Japan Public Health Center-Based Prospective Study
    Ribeka Takachi
    Department of Clinical Epidemiology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Am J Epidemiol 167:59-70. 2008
    ..16) for vegetables. This prospective cohort study demonstrated that, in the Japanese population, consumption of fruit is associated with lower risk of CVD, whereas fruit or vegetables may not be associated with lower risk of total cancer...
  60. ncbi request reprint Association between CDH1 haplotypes and gastric cancer risk in a Japanese population
    Hidetaka Yamada
    First Department of Pathology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
    Scand J Gastroenterol 42:1479-85. 2007
    ....
  61. doi request reprint Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population
    Shinobu Ikeda
    Department of Molecular Epidemiology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan
    Am J Gastroenterol 103:1476-87. 2008
    ..To investigate the association between polymorphisms and gastrointestinal (gastric and colorectal) cancer, we performed a hospital-based case-control study in Japan...
  62. ncbi request reprint The effect of 5-year vitamin C supplementation on serum pepsinogen level and Helicobacter pylori infection
    Shizuka Sasazuki
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa 277 8577, Japan
    Cancer Sci 94:378-82. 2003
    ..25 for the low-dose group and - 0.13 for the high-dose group (P = 0.046). To conclude, vitamin C supplementation may protect against progression of gastric mucosal atrophy...
  63. doi request reprint Female reproductive factors and the risk of gastric cancer in a large-scale population-based cohort study in Japan (JPHC study)
    Christina Persson
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 17:345-53. 2008
    ..Although early estrogen exposure may have some protective effect, female reproductive factors may have no substantial influence on gastric cancer development...
  64. ncbi request reprint [Peptic ulcer and environmental factor: with special focus on Helicobacter pylori infection]
    Masayuki Tatemichi
    Department of Environmental and Occupational Health, Toho University School of Medicine
    Nihon Rinsho 60:179-83. 2002
  65. ncbi request reprint Urinary level of 1,N(6) -ethenodeoxyadenosine, a marker of oxidative stress, is associated with salt excretion and omega 6-polyunsaturated fatty acid intake in postmenopausal Japanese women
    Tomoyuki Hanaoka
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Chiba, Japan
    Int J Cancer 100:71-5. 2002
    ..08). Results from this pilot study suggest urinary epsilon dA as a potential biomarker of DNA damage possibly derived from salt-induced inflammation and LPO; further exploration of epsilon dA in human biomonitoring studies is warranted...
  66. ncbi request reprint Cigarette smoking, alcohol consumption and subsequent gastric cancer risk by subsite and histologic type
    Shizuka Sasazuki
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa City, Japan
    Int J Cancer 101:560-6. 2002
    ..Further studies with more cases are needed to detect a positive association between cigarette smoking or alcohol consumption and cardia cancer...
  67. ncbi request reprint Vegetables, fruit and risk of gastric cancer in Japan: a 10-year follow-up of the JPHC Study Cohort I
    Minatsu Kobayashi
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Japan
    Int J Cancer 102:39-44. 2002
    ..Although no striking differences in the association were seen between cardia and noncardia cancer, an inverse association was higher in differentiated rather than in undifferentiated types of gastric cancer...
  68. ncbi request reprint Risk factors for stomach cancer in Brazil (I): a case-control study among non-Japanese Brazilians in São Paulo
    Ines Nobuko Nishimoto
    Research Center, Hospital do Cancer A C Camargo, Sao Paulo, Brazil
    Jpn J Clin Oncol 32:277-83. 2002
    ..Nevertheless, there are no reports of analytical epidemiological study on stomach cancer in Brazil...
  69. ncbi request reprint Risk factors for stomach cancer in Brazil (II): a case-control study among Japanese Brazilians in São Paulo
    Gerson Shigueaki Hamada
    Nikkei Disease Prevention Center, Santa Cruz Hospital, Sao Paulo, Brazil
    Jpn J Clin Oncol 32:284-90. 2002
    ..Although stomach cancer is the most frequent cancer among Japanese Brazilians, the risk factor of this cancer has not been investigated among them...
  70. ncbi request reprint Lack of long-term effect of vitamin C supplementation on blood pressure
    Mi Kyung Kim
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Japan
    Hypertension 40:797-803. 2002
    ..In conclusion, we observed no reduction in blood pressure with long-term moderate doses (500 mg/day) of vitamin C supplementation in a high-risk population for stomach cancer and stroke...
  71. ncbi request reprint Validity of the self-administered food frequency questionnaire used in the 5-year follow-up survey for the JPHC Study to assess folate, vitamin B6 and B12 intake: comparison with dietary records and blood level
    Hiroyasu Iso
    Department of Public Health Medicine, Institute of Community Medicine, University of Tsukuba
    J Epidemiol 13:S98-101. 2003
    ....
  72. ncbi request reprint Ethnic difference in serology of Helicobacter pylori CagA between Japanese and non-Japanese Brazilians for non-cardia gastric cancer
    Masayuki Tatemichi
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577
    Cancer Sci 94:64-9. 2003
    ....
  73. ncbi request reprint Seasonal misclassification error and magnitude of true between-person variation in dietary nutrient intake: a random coefficients analysis and implications for the Japan Public Health Center (JPHC) Cohort Study
    Michael T Fahey
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, 6 5 1 Kashiwanoha, Kashiwa shi, Chiba ken, 277 8577 Japan
    Public Health Nutr 6:385-91. 2003
    ..These effects could lead, respectively, to bias in estimates of relative risk for associations between usual nutrient exposure and disease, and to an increase in required sample size...
  74. ncbi request reprint Food/nutrient intake and risk of atrophic gastritis among the Helicobacter pylori-infected population of northeastern Japan
    Ai Montani
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba 277 8577, Japan
    Cancer Sci 94:372-7. 2003
    ..From these results, it is suggested that the dietary habits of consumers of traditional Japanese foods may play a role in the development of atrophic gastritis after H. pylori infection...
  75. ncbi request reprint Negative psychological aspects and survival in lung cancer patients
    Naoki Nakaya
    Psycho Oncology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Japan
    Psychooncology 17:466-73. 2008
    ....
  76. ncbi request reprint Atrophic gastritis, Helicobacter pylori, and colorectal cancer risk: a case-control study
    Ai Machida-Montani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Helicobacter 12:328-32. 2007
    ..However, the correlation between H. pylori and colorectal cancer (CRC) is controversial. The aim of this study was to examine the correlation between H. pylori, serum gastrin level, and atrophic gastritis with CRC...
  77. ncbi request reprint Maintenance of a low-sodium, high-carotene and -vitamin C diet after a 1-year dietary intervention: the Hiraka dietary intervention follow-up study
    Yoshiko Takahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Prev Med 43:14-9. 2006
    ..The difficulty of implementing and sustaining long-term changes is also well documented. Nevertheless, a few studies have attempted to achieve significant dietary change for extended periods...
  78. ncbi request reprint Blood pressure change in a free-living population-based dietary modification study in Japan
    Yoshiko Takahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention, Tokyo, Japan
    J Hypertens 24:451-8. 2006
    ..To assess whether dietary intervention in free-living healthy subjects is effective in improving blood pressure levels...
  79. ncbi request reprint Tobacco smoking and colorectal cancer risk: an evaluation based on a systematic review of epidemiologic evidence among the Japanese population
    Tetsuya Mizoue
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashiku, Fukuoka 812 8582, Japan
    Jpn J Clin Oncol 36:25-39. 2006
    ..It is unclear whether tobacco smoking is related to colorectal cancer risk in Japan. We evaluated the association among the Japanese population based on a systematic review of epidemiologic evidence...
  80. ncbi request reprint Folate, vitamin B6, vitamin B12, and vitamin B2 intake, genetic polymorphisms of related enzymes, and risk of colorectal cancer in a hospital-based case-control study in Japan
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tsukjii, Tokyo
    Nutr Cancer 53:42-50. 2005
    ..02) with colorectal cancer, although the other polymorphisms did not interact with any nutrient intake. In conclusion, the study did not support the existing hypothesis of gene-nutrient interaction in colorectal carcinogenesis...
  81. ncbi request reprint Alcohol consumption, smoking, and subsequent risk of colorectal cancer in middle-aged and elderly Japanese men and women: Japan Public Health Center-based prospective study
    Tetsuya Otani
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Chiba, Japan
    Cancer Epidemiol Biomarkers Prev 12:1492-500. 2003
    ..In conclusion, approximately half of the colorectal cancer cases may be preventable by tobacco and alcohol controls in middle-aged and elderly Japanese men...
  82. ncbi request reprint Long-term vitamin C supplementation has no markedly favourable effect on serum lipids in middle-aged Japanese subjects
    Mi Kyung Kim
    Department of Preventive Medicine, The Catholic University of Korea, Seoul, Korea
    Br J Nutr 91:81-90. 2004
    ..However, our present results do not preclude the possibility that vitamin C supplementation may decrease triacylglycerol concentrations among women with hypertriacylglycerolaemia...
  83. ncbi request reprint Association of habitual smoking and drinking with single nucleotide polymorphism (SNP) in 40 candidate genes: data from random population-based Japanese samples
    Ying Liu
    Epidemiology and Prevention Division, Research Center of Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    J Hum Genet 50:62-8. 2005
    ..The findings of the present study suggest that polymorphism in associated candidate genes plays a role in the habitual use of tobacco and alcohol among Japanese men...
  84. ncbi request reprint Salt, salted food intake, and risk of gastric cancer: epidemiologic evidence
    Shoichiro Tsugane
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045
    Cancer Sci 96:1-6. 2005
    ....
  85. ncbi request reprint hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gastric cancer risk in Japanese populations
    Hiromasa Tsukino
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Cancer Sci 95:977-83. 2004
    ..The results of the present study suggest that patients with atrophic gastritis in conjunction with the hOGG1 Cys allele might have a higher susceptibility to gastric cancer...
  86. ncbi request reprint Active and passive smoking and breast cancer risk in middle-aged Japanese women
    Tomoyuki Hanaoka
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Int J Cancer 114:317-22. 2005
    ..6; 95% CI = 1.3-5.2) but not in postmenopausal women (RR = 0.7; 95% CI = 0.4-1.0). We conclude that tobacco smoking increases the risk of female breast cancer in premenopausal women...
  87. ncbi request reprint Fish, long-chain n-3 polyunsaturated fatty acids, and risk of colorectal cancer in middle-aged Japanese: the JPHC study
    Minatsu Kobayashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Nutr Cancer 49:32-40. 2004
    ..This study does not support the role of fish and Ln-3 PUFA in the etiology of colon and rectal cancer in this population whose fish consumption was high and the variation in Ln-3 PUFA consumption was large...
  88. ncbi request reprint [Dietary factor and cancer risk--evidence from epidemiological studies]
    Shoichiro Tsugane
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuoku, Tokyo 104 0045, Japan
    Gan To Kagaku Ryoho 31:847-52. 2004
    ....
  89. ncbi request reprint Vegetables, fruit consumption and risk of lung cancer among middle-aged Japanese men and women: JPHC study
    Ying Liu
    Statistics and Cancer Control Division, National Cancer Center, Tokyo, Japan
    Cancer Causes Control 15:349-57. 2004
    ..To investigate the association between vegetable and fruit consumption and incidence of lung cancer...
  90. ncbi request reprint Prospective study of three major dietary patterns and risk of gastric cancer in Japan
    Mi Kyung Kim
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 110:435-42. 2004
    ..These associations persisted in histologic subtypes. Our findings support the idea that the healthy pattern decreased the risk of gastric cancer among females, while the traditional pattern increased the risk in both genders...
  91. ncbi request reprint Tobacco smoking and lung cancer risk: an evaluation based on a systematic review of epidemiological evidence among the Japanese population
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Jpn J Clin Oncol 36:309-24. 2006
    ..It would be of value, therefore, to quantify that association in Japan based on a systematic review of epidemiological evidence for the primary prevention of lung cancer...
  92. ncbi request reprint Tobacco smoking and breast cancer risk: an evaluation based on a systematic review of epidemiological evidence among the Japanese population
    Chisato Nagata
    Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, Gifu, Japan
    Jpn J Clin Oncol 36:387-94. 2006
    ..As tobacco smoking may be one of the few modifiable risk factors for breast cancer, we focused on the association between tobacco smoking and the risk of breast cancer in this review...
  93. ncbi request reprint Low intake of vitamin B-6 is associated with increased risk of colorectal cancer in Japanese men
    Junko Ishihara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    J Nutr 137:1808-14. 2007
    ..Our results support previous evidence that low vitamin B-6 intake is associated with an increased risk of colorectal cancer. In particular, a higher intake of vitamin B-6 appears beneficial in men with higher alcohol intake...
  94. ncbi request reprint Susceptibility to lung cancer and genetic polymorphisms in the alcohol metabolite-related enzymes alcohol dehydrogenase 3, aldehyde dehydrogenase 2, and cytochrome P450 2E1 in the Japanese population
    Yuji Minegishi
    Division of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan
    Cancer 110:353-62. 2007
    ....
  95. ncbi request reprint Effect of soy isoflavones on endometriosis: interaction with estrogen receptor 2 gene polymorphism
    Masaki Tsuchiya
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Epidemiology 18:402-8. 2007
    ..We examined associations among soy isoflavone intake, estrogen receptor 2 (ESR2) gene polymorphisms and risk of endometriosis...
  96. ncbi request reprint Coffee consumption and risk of colorectal cancer in a population-based prospective cohort of Japanese men and women
    Kyung Jae Lee
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 121:1312-8. 2007
    ..These findings suggest that coffee consumption may lower the risk of colon cancer among Japanese women...
  97. ncbi request reprint Body mass index, physical activity and the risk of pancreatic cancer in relation to smoking status and history of diabetes: a large-scale population-based cohort study in Japan--the JPHC study
    Juhua Luo
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Cancer Causes Control 18:603-12. 2007
    ..In particular, we explored how these effects were influenced by smoking status and a history of diabetes...
  98. ncbi request reprint Soy product and isoflavone consumption in relation to prostate cancer in Japanese men
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo 104 0045 Japan
    Cancer Epidemiol Biomarkers Prev 16:538-45. 2007
    ..52 [95% confidence interval (95% CI), 0.30-0.90], 0.50 (95% CI, 0.28-0.88), and 0.52 (95% CI, 0.29-0.90), respectively. In conclusion, we found that isoflavone intake was associated with a decreased risk of localized prostate cancer...
  99. ncbi request reprint Colorectal cancer screening using fecal occult blood test and subsequent risk of colorectal cancer: a prospective cohort study in Japan
    Kyung Jae Lee
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Detect Prev 31:3-11. 2007
    ..To investigate prospectively the association between colorectal cancer screening and subsequent risk of colorectal cancer death in a large-scale population-based cohort study (the JPHC study) with a 13-year follow-up period in Japan...
  100. ncbi request reprint Prospective study showing that dietary vitamin C reduced the risk of age-related cataracts in a middle-aged Japanese population
    Masao Yoshida
    Dept of Public Health, Kyorin University School of Medicine, Tokyo, Japan
    Eur J Nutr 46:118-24. 2007
    ....
  101. ncbi request reprint Physical activity and risk of colorectal cancer in Japanese men and women: the Japan Public Health Center-based prospective study
    Kyung Jae Lee
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo, Japan
    Cancer Causes Control 18:199-209. 2007
    ....