J Sugawara

Summary

Affiliation: National Institute of Advanced Industrial Science and Technology
Country: Japan

Publications

  1. doi request reprint Effect of systemic α1-adrenergic receptor blockade on central blood pressure response during exercise
    Jun Sugawara
    Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, 1 1 1 Higashi, Tsukuba, 305 8566, Japan
    J Physiol Sci 63:389-93. 2013
  2. doi request reprint Impact of chronic exercise training on the blood pressure response to orthostatic stimulation
    Jun Sugawara
    Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    J Appl Physiol 112:1891-6. 2012
  3. doi request reprint Effect of endurance exercise training and curcumin intake on central arterial hemodynamics in postmenopausal women: pilot study
    Jun Sugawara
    Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Japan
    Am J Hypertens 25:651-6. 2012
  4. ncbi request reprint Brachial-ankle pulse wave velocity: an index of central arterial stiffness?
    J Sugawara
    Institute for Human Science and Bioengineering, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    J Hum Hypertens 19:401-6. 2005
  5. ncbi request reprint Relationship between augmentation index obtained from carotid and radial artery pressure waveforms
    Jun Sugawara
    Institute for Human Science and Bioengineering, National Institute of Advanced Industrial Science and Technology, Ibaraki, Japan
    J Hypertens 25:375-81. 2007
  6. ncbi request reprint Age-related effects of regular physical activity on hemostatic factors in men
    Jun Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba Central 6, Tsukuba, Ibaraki 305 8566, Japan
    J Thromb Thrombolysis 26:203-10. 2008
  7. ncbi request reprint Physical activity duration, intensity, and arterial stiffening in postmenopausal women
    Jun Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Japan
    Am J Hypertens 19:1032-6. 2006
  8. ncbi request reprint Effect of arterial lumen enlargement on carotid arterial compliance in normotensive postmenopausal women
    Jun Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    Hypertens Res 28:323-9. 2005
  9. ncbi request reprint Effect of low-intensity aerobic exercise training on arterial compliance in postmenopausal women
    Jun Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Higashi, Tsukuba, Japan
    Hypertens Res 27:897-901. 2004
  10. pmc Distal shift of arterial pressure wave reflection sites with aging
    Jun Sugawara
    Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Hypertension 56:920-5. 2010

Detail Information

Publications42

  1. doi request reprint Effect of systemic α1-adrenergic receptor blockade on central blood pressure response during exercise
    Jun Sugawara
    Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, 1 1 1 Higashi, Tsukuba, 305 8566, Japan
    J Physiol Sci 63:389-93. 2013
    ....
  2. doi request reprint Impact of chronic exercise training on the blood pressure response to orthostatic stimulation
    Jun Sugawara
    Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    J Appl Physiol 112:1891-6. 2012
    ....
  3. doi request reprint Effect of endurance exercise training and curcumin intake on central arterial hemodynamics in postmenopausal women: pilot study
    Jun Sugawara
    Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Japan
    Am J Hypertens 25:651-6. 2012
    ....
  4. ncbi request reprint Brachial-ankle pulse wave velocity: an index of central arterial stiffness?
    J Sugawara
    Institute for Human Science and Bioengineering, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    J Hum Hypertens 19:401-6. 2005
    ..These results suggest that baPWV may provide qualitatively similar information to those derived from central arterial stiffness although some portions of baPWV may be determined by peripheral arterial stiffness...
  5. ncbi request reprint Relationship between augmentation index obtained from carotid and radial artery pressure waveforms
    Jun Sugawara
    Institute for Human Science and Bioengineering, National Institute of Advanced Industrial Science and Technology, Ibaraki, Japan
    J Hypertens 25:375-81. 2007
    ..The aim of this study was to examine whether AI obtained directly from radial artery pressure waveforms (radial AI) can provide information comparable with carotid arterial AI measurements...
  6. ncbi request reprint Age-related effects of regular physical activity on hemostatic factors in men
    Jun Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba Central 6, Tsukuba, Ibaraki 305 8566, Japan
    J Thromb Thrombolysis 26:203-10. 2008
    ..The purpose of this study was to assess the effects of age, regular aerobic exercise and detraining on blood coagulation and fibrinolytic factors in men...
  7. ncbi request reprint Physical activity duration, intensity, and arterial stiffening in postmenopausal women
    Jun Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Japan
    Am J Hypertens 19:1032-6. 2006
    ..Using a cross-sectional and interventional approach, we tested the hypothesis that both moderate and vigorous physical activity reduce central arterial stiffness in postmenopausal women...
  8. ncbi request reprint Effect of arterial lumen enlargement on carotid arterial compliance in normotensive postmenopausal women
    Jun Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    Hypertens Res 28:323-9. 2005
    ....
  9. ncbi request reprint Effect of low-intensity aerobic exercise training on arterial compliance in postmenopausal women
    Jun Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Higashi, Tsukuba, Japan
    Hypertens Res 27:897-901. 2004
    ..Accordingly, even low-intensity exercise training may have the effect of improving central arterial compliance...
  10. pmc Distal shift of arterial pressure wave reflection sites with aging
    Jun Sugawara
    Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Hypertension 56:920-5. 2010
    ..35). These results suggest that the major reflection site shifts distally with aging partly because of the closer matching of impedance provided by central and peripheral arterial stiffness...
  11. ncbi request reprint Reductions in basal limb blood flow and lumen diameter after short-term leg casting
    Jun Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Med Sci Sports Exerc 36:1689-94. 2004
    ..We tested the hypotheses that short-term casting immobilization of a leg would reduce basal blood flow and vascular conductance and induces structural alterations in femoral artery...
  12. doi request reprint Effect of mirthful laughter on vascular function
    Jun Sugawara
    National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Am J Cardiol 106:856-9. 2010
    ..63). These results suggest that mirthful laughter elicited by comic movies induces beneficial impact on vascular function...
  13. pmc Involvement of endothelin-1 in habitual exercise-induced increase in arterial compliance
    S Maeda
    Center for Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba, Ibaraki, Japan
    Acta Physiol (Oxf) 196:223-9. 2009
    ..The aim of the present study was to examine whether ET-1 is involved in the mechanisms underlying the increase in central arterial compliance with aerobic exercise training...
  14. ncbi request reprint Effects of exercise training of 8 weeks and detraining on plasma levels of endothelium-derived factors, endothelin-1 and nitric oxide, in healthy young humans
    S Maeda
    Institute of Health and Sport Sciences, University of Tsukuba, Ibaraki, Japan
    Life Sci 69:1005-16. 2001
    ..e., vasodilative and antiatherosclerotic) on the cardiovascular system...
  15. pmc Effects of leg resistance training on arterial function in older men
    S Maeda
    Center for Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba, Ibaraki 305 8577, Japan
    Br J Sports Med 40:867-9. 2006
    ..Little information is available on the effect of strength training on vascular function, particularly in older people...
  16. ncbi request reprint Fluctuations in carotid arterial distensibility during the menstrual cycle do not influence cardiovagal baroreflex sensitivity
    K Hayashi
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Acta Physiol (Oxf) 186:103-10. 2006
    ..This study was designed to test the hypothesis that fluctuations in cardiovagal baroreflex sensitivity (BRS) throughout the menstrual cycles of young women are due to fluctuations in carotid arterial distensibility...
  17. ncbi request reprint Age-related reduction of systemic arterial compliance induces excessive myocardial oxygen consumption during sub-maximal exercise
    Takeshi Otsuki
    Center for Tsukuba Advanced Research Alliance TARA, University of Tsukuba, Tsukuba, Japan
    Hypertens Res 29:65-73. 2006
    ....
  18. doi request reprint Arterial stiffness, physical activity, and atrial natriuretic Peptide gene polymorphism in older subjects
    Motoyuki Iemitsu
    Center for Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba, Japan
    Hypertens Res 31:767-74. 2008
    ..Our results suggest that ANP polymorphism in older Japanese subjects may affect the cardiovascular response to regular exercise...
  19. ncbi request reprint Diurnal variations of post-exercise parasympathetic nervous reactivation in different chronotypes
    J Sugawara
    Doctoral Program in Health and Sports Sciences, University of Tsukuba, Ibaraki, Japan
    Jpn Heart J 42:163-71. 2001
    ..These results suggest that diurnal variation in post-exercise vagal reactivation is different between morning-type and evening-type, and post-exercise vagal reactivation in evening-type individuals is sluggish in the morning...
  20. ncbi request reprint Polymorphism in endothelin-related genes limits exercise-induced decreases in arterial stiffness in older subjects
    Motoyuki Iemitsu
    Center for Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba, Ibaraki 305 8577, Japan
    Hypertension 47:928-36. 2006
    ..The present results suggest that differences in ET-A and ET-B polymorphisms may influence the response of the vascular wall to exercise whereas ECE-1 polymorphisms may affect basal blood pressure...
  21. ncbi request reprint Effect of systemic nitric oxide synthase inhibition on arterial stiffness in humans
    Jun Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    Hypertens Res 30:411-5. 2007
    ..8+/-1.2 vs. 9.1+/-1.1 U) but increased (p<0.05) after NO synthase inhibition (12.6+/-2.0 U). These results suggest that NO appears to modulate central arterial stiffness in humans...
  22. ncbi request reprint Systemic alpha-adrenergic and nitric oxide inhibition on basal limb blood flow: effects of endurance training in middle-aged and older adults
    Jun Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Ibaraki, Japan
    Am J Physiol Heart Circ Physiol 293:H1466-72. 2007
    ....
  23. ncbi request reprint Non-invasive assessment of cardiac output during exercise in healthy young humans: comparison between Modelflow method and Doppler echocardiography method
    J Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology AIST, Namiki, Tsukuba, Ibaraki, Japan
    Acta Physiol Scand 179:361-6. 2003
    ..We tested the reliability of a non-invasive cardiac output estimation during submaximal exercise using the Modelflow method from finger arterial pressure waveforms collected by Portapres in healthy young humans...
  24. doi request reprint Regular endurance exercise in young men increases arterial baroreflex sensitivity through neural alteration of baroreflex arc
    Hidehiko Komine
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology AIST Higashi 1 1 1, Tsukuba, Ibaraki 305 8566, Japan
    J Appl Physiol 106:1499-505. 2009
    ....
  25. pmc Reduction in alpha-adrenergic receptor-mediated vascular tone contributes to improved arterial compliance with endurance training
    Jun Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Ibaraki, Japan
    Int J Cardiol 135:346-52. 2009
    ..However, the underlying mechanisms are unknown. We tested the hypothesis that the improved central arterial compliance with endurance training is mediated by decreased alpha-adrenergic tone and/or increased endothelial function...
  26. ncbi request reprint Resistance exercise training reduces plasma endothelin-1 concentration in healthy young humans
    Seiji Maeda
    Center for Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba, Ibaraki, Japan
    J Cardiovasc Pharmacol 44:S443-6. 2004
    ....
  27. ncbi request reprint Effects of nitric oxide synthase inhibitor on decrease in peripheral arterial stiffness with acute low-intensity aerobic exercise
    Jun Sugawara
    Center for Tsukuba Advanced Research Alliance, Univ of Tsukuba, 1 1 1 Tennodai, Tsukuba, Ibaraki 305 8574, Japan
    Am J Physiol Heart Circ Physiol 287:H2666-9. 2004
    ..706). These results suggest that increased production of NO is not a major factor in the decrease of regional arterial stiffness with low-intensity, short-duration aerobic exercise...
  28. ncbi request reprint Variations in carotid arterial compliance during the menstrual cycle in young women
    Koichiro Hayashi
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, 1 1 1 Higashi, Tsukuba, Ibaraki, 305 8566, Japan
    Exp Physiol 91:465-72. 2006
    ..These data provide evidence that the elastic properties of central, but not peripheral, arteries fluctuate significantly with the phases of the menstrual cycle...
  29. ncbi request reprint Effects of aerobic exercise training on the stiffness of central and peripheral arteries in middle-aged sedentary men
    Koichiro Hayashi
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Jpn J Physiol 55:235-9. 2005
    ..These results suggest that in contrast with central arterial stiffness, peripheral arterial stiffness is difficult to change with aerobic exercise training...
  30. ncbi request reprint Postexercise heart rate recovery accelerates in strength-trained athletes
    Takeshi Otsuki
    Center for Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba, Ibaraki, Japan
    Med Sci Sports Exerc 39:365-70. 2007
    ..In addition, the acceleration of vagally mediated heart rate (HR) recovery after exercise is one of the functional adaptations of the heart in endurance-trained humans. However, the effect of strength training on HR recovery is unclear...
  31. ncbi request reprint The effects of low-intensity single-leg exercise on regional arterial stiffness
    Jun Sugawara
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Tsukuba, 305 8564 Japan
    Jpn J Physiol 53:239-41. 2003
    ..After the exercise, the velocity significantly decreased in the exercised leg, but not in the counterpart, suggesting that the decrease in arterial stiffness in the exercised leg was induced mainly by exercise-related regional factors...
  32. doi request reprint Acute exercise increases systemic arterial compliance after 6-month exercise training in older women
    Seiji Maeda
    Institute of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan
    Hypertens Res 31:377-81. 2008
    ....
  33. ncbi request reprint Aerobic exercise training reduces plasma endothelin-1 concentration in older women
    Seiji Maeda
    Centre for Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba, Ibaraki 305 0006, Japan
    J Appl Physiol 95:336-41. 2003
    ..e., prevention of progression of hypertension and/or atherosclerosis by endogenous ET-1)...
  34. doi request reprint Combination of polymorphisms in the beta2-adrenergic receptor and nitric oxide synthase 3 genes increases the risk for hypertension
    Maiko Misono
    Division of Sports Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan
    J Hypertens 27:1377-83. 2009
    ..We hypothesized that a combination of these two polymorphisms increases the risk for hypertension. Hence, we examined the effect of this combination of single-nucleotide polymorphisms on the risk for hypertension...
  35. ncbi request reprint Age-related reductions in appendicular skeletal muscle mass: association with habitual aerobic exercise status
    Jun Sugawara
    Department of Kinesiology and Applied Physiology, University of Colorado, Boulder, CO, USA
    Clin Physiol Funct Imaging 22:169-72. 2002
    ..This may contribute, at least in part, to the lower incidence of functional disability observed in middle-aged and older men who exercise regularly...
  36. ncbi request reprint Unfavorable effects of resistance training on central arterial compliance: a randomized intervention study
    Motohiko Miyachi
    Division of Health Promotion and Exercise, National Institute of Health and Nutrition, Shinjuku, Tokyo 162 8636, Japan
    Circulation 110:2858-63. 2004
    ..Endurance training is efficacious in increasing arterial compliance in healthy adults. We determined the effects of resistance training on carotid arterial compliance using the intervention study design...
  37. ncbi request reprint Effects of short-term endurance training on aortic distensibility in young males
    Tetsuji Kakiyama
    Faculty of Wellness Studies, Kwassui Women s College, 1 50, Higashiyamate machi, Nagasaki 850 8515, Japan
    Med Sci Sports Exerc 37:267-71. 2005
    ..Short-term endurance exercise training can increase aortic distensibility. The effect of exercise on arterial distensibility, however, may not last long term...
  38. ncbi request reprint Age-related reduction of systemic arterial compliance relates to decreased aerobic capacity during sub-maximal exercise
    Takeshi Otsuki
    Center for Tsukuba Advanced Research Alliance, University of Tsukuba, Japan
    Hypertens Res 29:759-65. 2006
    ..These results suggest that the participation of SAC in aerobic capacity is significant even during sub-maximal exercise in individuals who show a pronounced age-related reduction of SAC...
  39. doi request reprint Estrogen receptor-alpha genotype affects exercise-related reduction of arterial stiffness
    Koichiro Hayashi
    Department of Music, Sapporo Otani University, Sapporo, Hokkaido, Japan
    Med Sci Sports Exerc 40:252-7. 2008
    ....
  40. ncbi request reprint Sex differences in the relationship between estrogen receptor alpha gene polymorphisms and arterial stiffness in older humans
    Koichiro Hayashi
    Department of Music, Sapporo Otani College, Sapporo, Hokkaido, Japan
    Am J Hypertens 20:650-6. 2007
    ..We hypothesized that the relationship between arterial stiffness and gene polymorphisms in ER-alpha has a sex-specific component in older humans...
  41. pmc Interrelationships among noninvasive measures of postischemic macro- and microvascular reactivity
    Mandeep Dhindsa
    Department of Kinesiology and Health Education, University of Texas at Austin, Austin, TX 78712, USA
    J Appl Physiol 105:427-32. 2008
    ..These results suggest that different physiological mechanisms may be involved in changing different measures of vascular reactivity...
  42. ncbi request reprint Moderate regular exercise increases basal production of nitric oxide in elderly women
    Seiji Maeda
    Center for Tsukuba Advanced Research Alliance TARA, Institute of Health and Sport Sciences, University of Tsukuba, Japan
    Hypertens Res 27:947-53. 2004
    ..e., antihypertensive and antiatherosclerotic effects by endogenous NO) on the cardiovascular system...