Kazuaki Shimada

Summary

Affiliation: National Cancer Center
Country: Japan

Publications

  1. ncbi request reprint Complete drainage of pancreatic juice from the cut edge of the pancreas after subtotal left-side pancreatectomy
    K Shimada
    Department of Surgery, National Cancer Center Hospital, Tokyo, Japan
    Hepatogastroenterology 47:1156-8. 2000
  2. ncbi request reprint Surgical outcomes of the mass-forming plus periductal infiltrating types of intrahepatic cholangiocarcinoma: a comparative study with the typical mass-forming type of intrahepatic cholangiocarcinoma
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    World J Surg 31:2016-22. 2007
  3. ncbi request reprint Safety and effectiveness of left hepatic trisegmentectomy for hilar cholangiocarcinoma
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, 5 1 1, Tsukiji, 104 0045, Chuo Ku, Tokyo, Japan
    World J Surg 29:723-7. 2005
  4. ncbi request reprint Analysis of prognostic factors affecting survival after initial recurrence and treatment efficacy for recurrence in patients undergoing potentially curative hepatectomy for hepatocellular carcinoma
    Kazuaki Shimada
    Division of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, Tokyo, Japan
    Ann Surg Oncol 14:2337-47. 2007
  5. ncbi request reprint Clinical impact of the surgical margin status in hepatectomy for solitary mass-forming type intrahepatic cholangiocarcinoma without lymph node metastases
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Japan
    J Surg Oncol 96:160-5. 2007
  6. ncbi request reprint Clinical implications of combined portal vein resection as a palliative procedure in patients undergoing pancreaticoduodenectomy for pancreatic head carcinoma
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, 5 1 1, Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Ann Surg Oncol 13:1569-78. 2006
  7. ncbi request reprint A long-term follow-up and management study of hepatocellular carcinoma patients surviving for 10 years or longer after curative hepatectomy
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer 104:1939-47. 2005
  8. ncbi request reprint Safe management of the pancreatic remnant with prolamine duct occlusion after extended pancreaticoduodenectomy
    Kazuaki Shimada
    Department of Hepatobiliary Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Hepatogastroenterology 52:1874-7. 2005
  9. ncbi request reprint Reappraisal of the clinical significance of tumor size in patients with pancreatic ductal carcinoma
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, Tokyo 104 0045, Japan
    Pancreas 33:233-9. 2006
  10. ncbi request reprint Invasive carcinoma originating in an intraductal papillary mucinous neoplasm of the pancreas: a clinicopathologic comparison with a common type of invasive ductal carcinoma
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, Tokyo, Japan
    Pancreas 32:281-7. 2006

Detail Information

Publications92

  1. ncbi request reprint Complete drainage of pancreatic juice from the cut edge of the pancreas after subtotal left-side pancreatectomy
    K Shimada
    Department of Surgery, National Cancer Center Hospital, Tokyo, Japan
    Hepatogastroenterology 47:1156-8. 2000
    ..Since July 20, 1994, we have applied this method to 12 patients with carcinoma of the body and tail of the pancreas other than the present case and as yet have never experienced serious postoperative complications...
  2. ncbi request reprint Surgical outcomes of the mass-forming plus periductal infiltrating types of intrahepatic cholangiocarcinoma: a comparative study with the typical mass-forming type of intrahepatic cholangiocarcinoma
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    World J Surg 31:2016-22. 2007
    ..The purpose of this study was to clarify the clinicopathologic characteristics and surgical outcomes of patients with the mass-forming (MF) plus periductal infiltrating (PI) type of intrahepatic cholangiocellular carcinoma (ICC)...
  3. ncbi request reprint Safety and effectiveness of left hepatic trisegmentectomy for hilar cholangiocarcinoma
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, 5 1 1, Tsukiji, 104 0045, Chuo Ku, Tokyo, Japan
    World J Surg 29:723-7. 2005
    ..The incidence of positive resectional margin was 25%. With biliary decompression and preoperative portal embolization techniques, left hepatic trisegmentectomy was a safe and curative resectional option for hilar cholangiocarcinoma...
  4. ncbi request reprint Analysis of prognostic factors affecting survival after initial recurrence and treatment efficacy for recurrence in patients undergoing potentially curative hepatectomy for hepatocellular carcinoma
    Kazuaki Shimada
    Division of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, Tokyo, Japan
    Ann Surg Oncol 14:2337-47. 2007
    ..In addition, selections of the most effective treatments for patients with recurrent HCC still remain controversial...
  5. ncbi request reprint Clinical impact of the surgical margin status in hepatectomy for solitary mass-forming type intrahepatic cholangiocarcinoma without lymph node metastases
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Japan
    J Surg Oncol 96:160-5. 2007
    ..The clinical impact of the surgical margin status in macroscopic curative hepatectomy for intrahepatic cholangiocarcinoma (ICC) has not yet been fully investigated...
  6. ncbi request reprint Clinical implications of combined portal vein resection as a palliative procedure in patients undergoing pancreaticoduodenectomy for pancreatic head carcinoma
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, 5 1 1, Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Ann Surg Oncol 13:1569-78. 2006
    ..The clinical implications of combined portal vein resections are controversial...
  7. ncbi request reprint A long-term follow-up and management study of hepatocellular carcinoma patients surviving for 10 years or longer after curative hepatectomy
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer 104:1939-47. 2005
    ....
  8. ncbi request reprint Safe management of the pancreatic remnant with prolamine duct occlusion after extended pancreaticoduodenectomy
    Kazuaki Shimada
    Department of Hepatobiliary Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Hepatogastroenterology 52:1874-7. 2005
    ..However, ductal occlusion has not proved satisfactory for preventing pancreatic fistulas in pancreaticoduodenectomy (PD)...
  9. ncbi request reprint Reappraisal of the clinical significance of tumor size in patients with pancreatic ductal carcinoma
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, Tokyo 104 0045, Japan
    Pancreas 33:233-9. 2006
    ..Recent advances in diagnostic modalities have made it possible to detect small pancreatic ductal carcinoma and to increase the number of resected cases. However, the postoperative prognosis remains dismal...
  10. ncbi request reprint Invasive carcinoma originating in an intraductal papillary mucinous neoplasm of the pancreas: a clinicopathologic comparison with a common type of invasive ductal carcinoma
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, Tokyo, Japan
    Pancreas 32:281-7. 2006
    ..The aim of the present study was to investigate the clinicopathologic difference between invasive IPMN and a common type of invasive ductal carcinoma of the pancreas...
  11. ncbi request reprint Successful outcome after resection of pancreatic cancer with a solitary hepatic metastasis
    Kazuaki Shimada
    Department of Surgery, National Cancer Center Hospital, Tokyo, Japan
    Hepatogastroenterology 51:603-5. 2004
    ..Surgical resection may be an option for highly selected patients with pancreatic cancer complicated with hepatic metastasis...
  12. ncbi request reprint Prognostic factors after distal pancreatectomy with extended lymphadenectomy for invasive pancreatic adenocarcinoma of the body and tail
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Surgery 139:288-95. 2006
    ..Factors predicting survival were not evaluated fully in patients with invasive pancreatic carcinoma of the body and tail who had undergone distal pancreatectomy with extended lymphadenectomy...
  13. ncbi request reprint Role of a hepatectomy for the treatment of large hepatocellular carcinomas measuring 10 cm or larger in diameter
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Central Hospital, Tokyo, Japan
    Langenbecks Arch Surg 393:521-6. 2008
    ..A curative hepatectomy is the mainstay of effective treatment for small hepatocellular carcinoma (HCC), but the treatment of large HCC remains challenging...
  14. doi request reprint Pseudoaneurysm of the cystic artery associated with xanthogranulomatous cholecystitis
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, Tokyo, Japan
    Dig Surg 25:8-9. 2008
  15. doi request reprint Role of medial pancreatectomy in the management of intraductal papillary mucinous neoplasms and islet cell tumors of the pancreatic neck and body
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Central Hospital, Tokyo, Japan
    Dig Surg 25:46-51. 2008
    ..However, the role of this procedure remains controversial. We investigate outcomes using this method in 14 patients...
  16. ncbi request reprint Role of the width of the surgical margin in a hepatectomy for small hepatocellular carcinomas eligible for percutaneous local ablative therapy
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Central Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Am J Surg 195:775-81. 2008
    ..There is intense clinical interest to determine whether a wide surgical margin is required to improve postoperative recurrence after locoregional therapy for small hepatocellular carcinomas (HCCs)...
  17. doi request reprint Therapeutic value of lymph node dissection during hepatectomy in patients with intrahepatic cholangiocellular carcinoma with negative lymph node involvement
    Kazuaki Shimada
    National Cancer Center Hospital, Tokyo, Japan
    Surgery 145:411-6. 2009
    ..The therapeutic value of the procedure during hepatectomy has, however, not been evaluated...
  18. doi request reprint Intrapancreatic nerve invasion as a predictor for recurrence after pancreaticoduodenectomy in patients with invasive ductal carcinoma of the pancreas
    Kazuaki Shimada
    National Cancer Center Hospital, Tokyo, Japan
    Pancreas 40:464-8. 2011
    ..Neural invasion is a distinct route for the spread of pancreatic carcinoma. However, the clinicopathologic significance of neural invasion, with particular reference to intrapancreatic nerve invasion, remains to be elucidated...
  19. doi request reprint Analysis of 5-year survivors after a macroscopic curative pancreatectomy for invasive ductal adenocarcinoma
    Kazuaki Shimada
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    World J Surg 34:1908-15. 2010
    ..Surgical resections for invasive ductal adenocarcinoma of the pancreas can provide the only chance of cure, although the 5-year survivors are not always equated with cure...
  20. doi request reprint Extended right hemihepatectomy for gallbladder carcinoma involving the hepatic hilum
    K Shimada
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Centre Hospital, Tokyo, Japan
    Br J Surg 98:117-23. 2011
    ..Major hemihepatectomy for advanced gallbladder carcinoma remains controversial as it is associated with serious postoperative complications and poor prognosis...
  21. ncbi request reprint Clinical significance of extrahepatic bile duct resection for advanced gallbladder cancer
    Yoshihiro Sakamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    J Surg Oncol 94:298-306. 2006
    ..The aim of this study was to determine the clinical significance of extrahepatic bile duct (EHBD) resection during surgery for advanced gallbladder cancer...
  22. ncbi request reprint Surgical management of infrahilar/suprapancreatic cholangiocarcinoma: an analysis of the surgical procedures, surgical margins, and survivals of 77 patients
    Yoshihiro Sakamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    J Gastrointest Surg 14:335-43. 2010
    ..Optical surgical management of infrahilar/suprapancreatic cholangiocarcinoma remains controversial...
  23. doi request reprint Preoperative evaluation of invasive and noninvasive intraductal papillary-mucinous neoplasms of the pancreas: clinical, radiological, and pathological analysis of 123 cases
    Satoshi Nara
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital Tokyo, Japan
    Pancreas 38:8-16. 2009
    ..We aimed to investigate preoperative findings that are useful to distinguish intraductal papillary-mucinous neoplasm (IPMN) subtypes...
  24. ncbi request reprint Combined hepatocellular and cholangiocarcinoma: a clinicopathologic study of 26 resected cases
    Yoshiko Yano
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Jpn J Clin Oncol 33:283-7. 2003
    ..The aim of this study was to clarify the characteristics of cHCC-CC in comparison with hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC)...
  25. doi request reprint Is surgical resection justified for stage IV colorectal cancer patients having bilobar hepatic metastases?--an analysis of survival of 77 patients undergoing hepatectomy
    Yoshihiro Sakamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    J Surg Oncol 102:784-8. 2010
    ..Surgical indication for stage IV colorectal cancer patients with bilobar hepatic metastases may be controversial...
  26. pmc One hundred two consecutive hepatobiliary resections for perihilar cholangiocarcinoma with zero mortality
    Tsuyoshi Sano
    Hepato Biliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tsukiji, Tokyo, Japan
    Ann Surg 244:240-7. 2006
    ..To analyze the short-term surgical outcome of hepatobiliary resections for perihilar cholangiocarcinoma in the last 5 years...
  27. ncbi request reprint Risk factors for early bilirubinemia after major hepatectomy for perihilar cholangiocarcinoma with portal vein embolization
    Yoshihiro Sakamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Hepatogastroenterology 57:22-8. 2010
    ..Major hepatectomy for perihilar cholangiocarcinoma has considerable risk of hepatic insufficiency even with preoperative portal vein embolization (PVE). Postoperative bilirubinemia is a great concern for hepatic surgeons...
  28. ncbi request reprint Liver cryptococcosis manifesting as obstructive jaundice in a young immunocompetent man: report of a case
    Satoshi Nara
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Surg Today 38:271-4. 2008
    ..Unnecessary surgical intervention was avoided by an early and accurate diagnosis and effective antifungal therapy. The bile culture was the key to the definitive diagnosis in this case...
  29. doi request reprint Is extended hemihepatectomy plus pancreaticoduodenectomy justified for advanced bile duct cancer and gallbladder cancer?
    Yoshihiro Sakamoto
    Hepato Biliary Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Surgery 153:794-800. 2013
    ..However, surgical morbidity associated with major HPD is high, and optimal indications for this procedure remain unclear...
  30. doi request reprint Pancreatic intraglandular metastasis predicts poorer outcome in postoperative patients with pancreatic ductal carcinoma
    Seiji Oguro
    Division of Molecular Pathology, National Cancer Center Research Institute, Tokyo, Japan
    Am J Surg Pathol 37:1030-8. 2013
    ..002; hazard ratio=2.239; 95% confidence interval: 1.328-3.773). Our findings suggest that the presence of P-IM in patients with PDC is an independent prognosticator and may represent aggressive tumor behavior...
  31. doi request reprint Pancreaticojejunostomy with invagination of the punched pancreatic remnant after medial pancreatectomy and enucleation for multiple metastases of renal cell carcinoma: report of a case
    Yasunori Deguchi
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Surg Today 39:1086-90. 2009
    ....
  32. doi request reprint Definition of T3/4 and regional lymph nodes in gallbladder cancer: which is more valid, the UICC or the Japanese staging system?
    Yoji Kishi
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Ann Surg Oncol 19:3567-73. 2012
    ....
  33. ncbi request reprint Hepatobiliary resection with inferior vena cava resection and reconstruction using an autologous patch graft for intrahepatic cholangiocarcinoma
    Tsuyoshi Sano
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Langenbecks Arch Surg 393:599-603. 2008
    ..In patients with advanced cholangiocarcinoma involving the inferior vena cava (IVC), an extended hepatobiliary resection with combined resection and reconstruction of the IVC is often prerequisite to obtain a clear resection margin...
  34. ncbi request reprint Prognosis of perihilar cholangiocarcinoma: hilar bile duct cancer versus intrahepatic cholangiocarcinoma involving the hepatic hilus
    Tsuyoshi Sano
    Hepato Biliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Ann Surg Oncol 15:590-9. 2008
    ..Clinically hepatobiliary resection is indicated for both hilar bile duct cancer (BDC) and intrahepatic cholangiocarcinoma involving the hepatic hilus (CCC). The aim of this study was to compare the long-term outcome of BDC and CCC...
  35. ncbi request reprint Wrapping the stump of the gastroduodenal artery using the falciform ligament during pancreaticoduodenectomy
    Yoshihiro Sakamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    J Am Coll Surg 204:334-6. 2007
  36. doi request reprint Clinicopathological characteristics of intrahepatic cholangiocellular carcinoma presenting intrahepatic bile duct growth
    Yusuke Yamamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Central Hospital, Tokyo, Japan
    J Surg Oncol 99:161-5. 2009
    ..Intrahepatic cholangiocellular carcinoma (ICC) presenting intraductal growth (IG) has distinct clinicopathological features with a favorable prognosis. The mass-forming (MF) plus IG type of ICC has not been previously investigated...
  37. ncbi request reprint Clinical significance of reconstruction of the right hepatic artery for biliary malignancy
    Yoshihiro Sakamoto
    Hepatobiliary and Pancreatic Surgery Division, Department of Surgery, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Langenbecks Arch Surg 391:203-8. 2006
    ..The clinical significance of resectional surgery with reconstruction of the right hepatic artery for biliary malignancy remains unclear...
  38. doi request reprint Perioperative and long-term outcomes after pancreaticoduodenectomy in elderly patients 80 years of age and older
    Seiji Oguro
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Langenbecks Arch Surg 398:531-8. 2013
    ..The aim of this study was to evaluate the perioperative and long-term outcomes following PD in patients 80 years of age and older...
  39. doi request reprint Periductal infiltrating type of intrahepatic cholangiocarcinoma: a rare macroscopic type without any apparent mass
    Masanori Uno
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Surg Today 42:1189-94. 2012
    ....
  40. doi request reprint Assessment of the interface between retroperitoneal fat infiltration of pancreatic ductal carcinoma and the major artery by multidetector-row computed tomography: surgical outcomes and correlation with histopathological extension
    Yusuke Yamamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Central Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    World J Surg 36:2192-201. 2012
    ..Precise assessment of retroperitoneal invasion is clinically important to allow the achievement of negative margin resections...
  41. ncbi request reprint Macrophage-capping protein as a tissue biomarker for prediction of response to gemcitabine treatment and prognosis in cholangiocarcinoma
    Noriaki Morofuji
    Division of Pharmacoproteomics, National Cancer Center Research Institute, Tokyo, Japan
    J Proteomics 75:1577-89. 2012
    ..In conclusion, CapG was identified as a novel candidate biomarker to predict response to gemcitabine treatment and survival in cholangiocarcinoma...
  42. ncbi request reprint Prognostic impact of postoperative serum CA 19-9 levels in patients with resectable pancreatic cancer
    Shojiro Hata
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Ann Surg Oncol 19:636-41. 2012
    ..The object of this study was to investigate the predictive factors for survival, including preoperative and postoperative serum CA 19-9 levels in patients with pancreatic cancer...
  43. ncbi request reprint Minimally invasive intraductal papillary-mucinous carcinoma of the pancreas: clinicopathologic study of 104 intraductal papillary-mucinous neoplasms
    Satoshi Nara
    Pathology Division, National Cancer Center Research Institute, Chuo Ku, Tokyo, Japan
    Am J Surg Pathol 32:243-55. 2008
    ..These findings suggest that a category of MI-IPMC provides more accurate and useful information of the stage and the aggressiveness of I-IPMC...
  44. doi request reprint Efficacy of a hepatectomy and a tumor thrombectomy for hepatocellular carcinoma with tumor thrombus extending to the main portal vein
    Daisuke Ban
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Central Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    J Gastrointest Surg 13:1921-8. 2009
    ..A thrombectomy remains the only therapeutic option that offer a chance of complete tumor removal avoiding acute portal vein obstruction. However, the efficacy of tumor thrombectomy in addition to hepatectomy has not been well evaluated...
  45. ncbi request reprint Changing trends in surgical outcomes after major hepatobiliary resection for hilar cholangiocarcinoma: a single-center experience over 25 years
    Tsuyoshi Sano
    Hepato Biliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Tokyo, 104 0045, Japan
    J Hepatobiliary Pancreat Surg 14:455-62. 2007
    ..The aim of this study was to characterize changes in surgical outcomes following major HBR for HCCa at a single center over a 25-year period...
  46. ncbi request reprint Prognostic factors of surgical resection in middle and distal bile duct cancer: an analysis of 55 patients concerning the significance of ductal and radial margins
    Yoshihiro Sakamoto
    Hepato Biliary and Pancreatic Surgery Division, Department of Surgery, National Cancer Center Hospital, 50101 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Surgery 137:396-402. 2005
    ..Although the resectional margin is known to be a predictive factor, the prognostic significance of a positive ductal margin and other radial margin has never been evaluated independently...
  47. ncbi request reprint Clinical significance of frozen section analysis during resection of intraductal papillary mucinous neoplasm: should a positive pancreatic margin for adenoma or borderline lesion be resected additionally?
    Satoshi Nara
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    J Am Coll Surg 209:614-21. 2009
    ....
  48. ncbi request reprint An analysis of risk factors for pancreatic fistula after pancreaticoduodenectomy: clinical impact of bile juice infection on day 1
    Takahiro Kajiwara
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Langenbecks Arch Surg 395:707-12. 2010
    ..The objective of this study is to reveal the risk factors for POPF defined by the international study group after pancreaticoduodenectomy in a Japanese high-volume center...
  49. ncbi request reprint Reconstruction of the portal and hepatic veins using venous grafts customized from the bilateral gonadal veins
    Yusuke Yamamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Langenbecks Arch Surg 394:1115-21. 2009
    ..Autologous venous grafts made from the bilateral gonadal veins (BGVs) have never been utilized or discussed...
  50. ncbi request reprint Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma
    Yasuhito Arai
    Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan
    Hepatology 59:1427-34. 2014
    ..This transforming ability was attributable to its kinase activity. Treatment with the fibroblast growth factor receptor (FGFR) kinase inhibitors BGJ398 and PD173074 effectively suppressed transformation...
  51. doi request reprint Is preservation of the remnant stomach safe during distal pancreatectomy in patients who have undergone distal gastrectomy?
    Hidenori Takahashi
    Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, 1 3 3 Nakamichi, Higashinari ku, Osaka 537 8511, Japan
    World J Surg 37:430-6. 2013
    ....
  52. ncbi request reprint Satellite lesions in patients with small hepatocellular carcinoma with reference to clinicopathologic features
    Takuji Okusaka
    Division of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, Japan
    Cancer 95:1931-7. 2002
    ..It is not rare to find satellite lesions in patients with small hepatocellular carcinoma (HCC). The purpose of this study was to elucidate the factors associated with satellite lesions in these patients...
  53. ncbi request reprint Favorable indications for hepatectomy in patients with liver metastasis from gastric cancer
    Yoshihiro Sakamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    J Surg Oncol 95:534-9. 2007
    ..The prognosis of patients with liver metastasis from gastric cancer (LMGC) is dismal. The purpose of this study was to review our recent outcomes of hepatectomy for LMGC and to determine the suitable candidates for surgery...
  54. doi request reprint Pancreatic ducts as an important route of tumor extension for acinar cell carcinoma of the pancreas
    Daisuke Ban
    Pathology Division, National Cancer Center Research Institute, Tokyo, Japan
    Am J Surg Pathol 34:1025-36. 2010
    ..These findings suggest that a significant proportion of ACC shows IPG, which is potentially linked to less aggressive clinicopathologic characteristics...
  55. ncbi request reprint The role of paraaortic lymph node involvement on early recurrence and survival after macroscopic curative resection with extended lymphadenectomy for pancreatic carcinoma
    Kazuaki Shimada
    Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, Tokyo, Japan
    J Am Coll Surg 203:345-52. 2006
    ..Early recurrence of invasive pancreatic cancer is common even after curative resection. To establish appropriate selection criteria for radical surgery, it is essential to identify the patient population at risk for early recurrence...
  56. ncbi request reprint Second hepatectomy for recurrent colorectal liver metastasis: analysis of preoperative prognostic factors
    Seiji Ishiguro
    Colorectal Surgery Division, National Cancer Center Hospital, 5 1 1, Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Ann Surg Oncol 13:1579-87. 2006
    ..However, there is still no consensus about the patient selection criteria for second hepatectomy under these circumstances, and the factors affecting prognosis after second hepatectomy remain uncertain...
  57. ncbi request reprint Effectiveness of hepatic resection for early-stage hepatocellular carcinoma in cirrhotic patients: subgroup analysis according to Milan criteria
    Junji Yamamoto
    Hepatobiliary and Pancreatic Section, Gastroenterological Division, Cancer Institute Hospital, Tokyo, Japan
    Jpn J Clin Oncol 37:287-95. 2007
    ..The aim of this study was to determine the long-term post-resection outcomes for cirrhotic patients with early-stage hepatocellular carcinoma (HCC)...
  58. ncbi request reprint Successful resection of hepatocellular carcinoma with bronchobiliary fistula caused by repeated transcatheter arterial embolizations: Report of a case
    Taizo Hibi
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Surg Today 37:154-8. 2007
    ..This is the first successfully resected case of HCC associated with BBF...
  59. ncbi request reprint Surgical results for hepatocellular carcinoma with bile duct invasion: a clinicopathologic comparison between macroscopic and microscopic tumor thrombus
    Minoru Esaki
    Department of Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    J Surg Oncol 90:226-32. 2005
    ..The aim of this study was to evaluate the prognostic factors and long-term results after surgery in patients with hepatocellular carcinoma (HCC) with bile duct invasion...
  60. doi request reprint Gemcitabine in patients with intraductal papillary mucinous neoplasm with an associated invasive carcinoma of the pancreas
    Taiga Otsuka
    Hepatobiliary and Pancreatic Oncology Division, National Cancer Center Hospital, Chuo Ku, Tokyo, Japan
    Pancreas 42:889-92. 2013
    ....
  61. ncbi request reprint Total pancreatectomy with en bloc celiac axis resection for a pancreatic adenocarcinoma involving both the gastroduodenal artery and the celiac artery
    Satoshi Nara
    National Cancer Center Hospital, Tokyo, Japan
    Hepatogastroenterology 59:1635-7. 2012
    ..2% but the precise evaluation of arterial anatomy is important to offer a chance of curative resection for patients with usually unresectable locally advanced pancreatic cancer...
  62. doi request reprint Is celiac axis resection justified for T4 pancreatic body cancer?
    Yusuke Yamamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Central Hospital, Tokyo, Japan
    Surgery 151:61-9. 2012
    ..The clinical impact of the distal pancreatectomy with en-bloc celiac axis resection for locally advanced pancreatic body cancer remains unclear...
  63. ncbi request reprint A solid pseudopapillary tumor arising from the greater omentum followed by multiple metastases with increasing malignant potential
    Taizo Hibi
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Tokyo, 104 0045, Japan
    J Gastroenterol 41:276-81. 2006
    ..This is the first detailed report of solid pseudopapillary tumor arising outside the pancreas complicated by repetitive liver metastases and peritoneal carcinomatosis, suggesting the existence of a more lethal subgroup of tumors...
  64. ncbi request reprint CT Evaluation of the progression of hypoattenuating nodular lesions in virus-related chronic liver disease
    Kenichi Takayasu
    Department of Diagnostic Radiology, National Cancer Center Hospital, 5 1 1, Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    AJR Am J Roentgenol 187:454-63. 2006
    ..The purpose of this study was to clarify the natural outcomes of hypoattenuating nodular lesions in patients with virus-related chronic liver disease depicted on dynamic CT...
  65. doi request reprint Prognosis of patients undergoing hepatectomy for solitary hepatocellular carcinoma originating in the caudate lobe
    Yoshihiro Sakamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Surgery 150:959-67. 2011
    ..The objective of this study is to investigate the clinicopathologic factors and survival of patients who underwent hepatectomy for solitary HCC originating in the caudate lobe...
  66. ncbi request reprint Surgery for hepatic neuroendocrine tumors: a single institutional experience in Japan
    Taizo Hibi
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Jpn J Clin Oncol 37:102-7. 2007
    ..We evaluated the results of Japanese patients to determine the prognostic factors and the feasibility of our aggressive surgical approach...
  67. doi request reprint A preoperative predictive scoring system for postoperative pancreatic fistula after pancreaticoduodenectomy
    Yusuke Yamamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    World J Surg 35:2747-55. 2011
    ..Postoperative pancreatic fistula (POPF) remains a leading cause of morbidity after pancreaticoduodenectomy (PD). In the present study we sought to establish a preoperative scoring system with which to predict this complication...
  68. doi request reprint Roux-en-Y reconstruction using staplers during pancreaticoduodenectomy: results of a prospective preliminary study
    Yoshihiro Sakamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Surg Today 39:32-7. 2009
    ..The aim of this study was to reveal the utility of alimentary reconstruction using staplers during pancreaticoduodenectomy (PD), focusing on the occurrence of delayed gastric emptying...
  69. ncbi request reprint Arterial reconstruction during pancreatoduodenectomy in patients with celiac axis stenosis--utility of Doppler ultrasonography
    Satoshi Nara
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Chuo Ku, Tokyo, Japan
    World J Surg 29:885-9. 2005
    ....
  70. ncbi request reprint Simple segmental resection of the second portion of the duodenum for the treatment of gastrointestinal stromal tumors
    Masami Asakawa
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Langenbecks Arch Surg 393:605-9. 2008
    ..Adequate surgical procedure for gastrointestinal stromal tumors (GISTs) arising in the second portion of the duodenum remains controversial...
  71. ncbi request reprint Reconstruction of hepatic venous tributaries using a Y-shaped left portal vein graft harvested from a resected left liver
    Tsuyoshi Sano
    Division of Hepatobiliary and Pancreatic Surgery, National Cancer Center Central Hospital, Chuou ku, Tokyo 104 0045, Japan
    Hepatogastroenterology 55:228-30. 2008
    ..In conclusion, this is the first report on the reconstruction of MHV tributaries using a single autologous Y-shaped portal vein graft during a hepatectomy. This method produces no complications related to the harvesting of the graft...
  72. ncbi request reprint Intraductal tubular carcinoma in an adenoma of the main pancreatic duct of the pancreas head
    Keita Itatsu
    Hepato Biliary and Pancreatic Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    J Gastroenterol 41:702-5. 2006
    ..MPD dilatation is a crucial sign and clue enabling the early detection of tiny pancreatic tumors...
  73. doi request reprint Long-term recurrence-free survival in a patient with primary hepatic carcinosarcoma: case report with a literature review
    Yusuke Yamamoto
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Central Hospital, Tokyo, Japan
    Jpn J Clin Oncol 40:166-73. 2010
    ..Since relatively early-stage hepatic carcinosarcoma rarely seems to present as a small tumor showing a concentric growth pattern, we report this case with a review of the literature...
  74. ncbi request reprint Extended right hemihepatectomy as a salvage operation for recurrent bile duct cancer 3 years after pancreatoduodenectomy
    Taizo Hibi
    Hepatobiliary and Pancreatic Surgery Division, National Cancer Center Hospital, Chuo Ku, Tokyo 104 0045, Japan
    Jpn J Clin Oncol 36:176-9. 2006
    ..An aggressive surgical approach will be a rational treatment of choice for recurrent disease when metachronous multicentric tumor development in the bile duct is suspected and curative resection can be safely performed...
  75. doi request reprint Intraductal carcinoma component as a favorable prognostic factor in biliary tract carcinoma
    Hidenori Ojima
    Pathology Division, National Cancer Center Research Institute, Tokyo, Japan
    Cancer Sci 100:62-70. 2009
    ..Surgeons should not be persistent in trying to achieve a negative surgical margin when the intraoperative frozen section diagnosis is R1 (is), and can choose a safe surgical procedure to avoid postoperative complications...
  76. ncbi request reprint Preoperative portal embolization in patients with hepatocellular carcinoma
    Yasuhiko Sugawara
    Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    World J Surg 26:105-10. 2002
    ..The atrophy effects were significant, especially when arterial embolization had been performed before portal vein embolization...
  77. ncbi request reprint Pancreatic metastasis from renal cell carcinoma extending into the main pancreatic duct: a case report
    Shinichi Yachida
    Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan
    Jpn J Clin Oncol 32:315-7. 2002
    ..This condition is similar to RCC extension into the renal vein and the inferior vena cava. In conclusion, although extension into the MPD may be rare, such a growth pattern may be characteristic of metastases from RCCs...
  78. ncbi request reprint Neovasculature of benign thrombus of the inferior vena cava demonstrated by computed tomography during hepatic arteriography, mimicking a small hepatocellular carcinoma
    Kenichi Takayasu
    Department of Diagnostic Radiology, National Cancer Center Hospital, Tokyo, Japan
    Jpn J Clin Oncol 33:44-6. 2003
    ..One should note that the stain shown on angiography does not always suggest that the lesion is localized in the liver and is malignant...
  79. ncbi request reprint Surgical treatment of pulmonary metastasis from hepatocellular carcinoma
    Norimasa Koide
    Division of Thoracic Surgery, National Cancer Center Hospital, Japan
    Hepatogastroenterology 54:152-6. 2007
    ..The lung is one of the most common sites of extrahepatic spread from hepatocellular carcinoma (HCC). The aim of this study was to evaluate the efficacy of surgical management in patients with pulmonary metastasis from HCC...
  80. doi request reprint A new histological classification for intra-operative histological examination of the ductal resection margin in cholangiocarcinoma
    Masaru Konishi
    Upper Gastric Surgery Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba, Japan
    Cancer Sci 100:255-60. 2009
    ....
  81. ncbi request reprint Surgery including liver resection for metastatic gastrointestinal stromal tumors or gastrointestinal leiomyosarcomas
    Souya Nunobe
    Department of Surgery, National Cancer Center, Tokyo, Japan
    Jpn J Clin Oncol 35:338-41. 2005
    ..The value of surgical resection, including hepatectomy, for metastatic GIST remains unknown. Our aim was to evaluate the outcome of surgical resection, including hepatectomy, for metastatic GIST at a single institute...
  82. ncbi request reprint His595Tyr polymorphism in the methionine synthase reductase (MTRR) gene is associated with pancreatic cancer risk
    Shumpei Ohnami
    Genetics Division, National Cancer Center Research Institute, Tokyo, Japan
    Gastroenterology 135:477-88. 2008
    ..This study attempts to elucidate a part of the genetic predisposition to the sporadic invasive ductal adenocarcinoma of the pancreas focusing on the genes implicated in the gene-environment interactions in carcinogenesis...
  83. ncbi request reprint Minute pancreatic adenocarcinoma presenting with stenosis of the main pancreatic duct
    Shinichi Yachida
    Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan
    Pathol Int 52:607-11. 2002
    ..Such changes in the MPD may therefore be of clinical importance in the detection of early stage cancers...
  84. doi request reprint Intraductal carcinosarcoma with a heterologous mesenchymal component originating in intraductal papillary-mucinous carcinoma (IPMC) of the pancreas with both carcinoma and osteosarcoma cells arising from IPMC cells
    Jun Okamura
    Pathology Division, National Cancer Center Research Institute, Tokyo 104 0045, Japan
    J Clin Pathol 63:266-9. 2010
    ..This is the first report of a carcinosarcoma originating in IPMC. These findings imply that carcinosarcoma with a heterologous mesenchymal component is of ductal origin...
  85. ncbi request reprint Imaging features of large intraductal papillary mucinous carcinoma of the pancreatic tail
    Yu Takahashi
    Pancreas 32:334-5. 2006
  86. ncbi request reprint [Surgical treatment of pancreatic cancer]
    Tomoo Kosuge
    HBP Surgery Division, National Cancer Center Hospital
    Nihon Rinsho 64:186-9. 2006
  87. ncbi request reprint Primary hepatocellular carcinoma detected long after tumor markers and lymph node metastases--beyond our vision?
    Jee Fu Huang
    Department of Internal Medicine, Fooyin University Hospital, Pingtung, Taiwan
    Dig Dis Sci 51:610-5. 2006
  88. ncbi request reprint Clear cell endocrine tumor of the pancreas which is not associated with von Hippel-Lindau disease: report of a case
    Souya Nunobe
    Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan
    Surg Today 33:470-4. 2003
    ..We conclusively diagnosed it to be a pancreatic clear cell endocrine tumor. Such tumors not associated with von Hippel-Lindau disease are extremely rare...
  89. ncbi request reprint Clinicopathological significance of galectin-3 expression in ductal adenocarcinoma of the pancreas
    Takeshi Shimamura
    Pathology Division, National Cancer Center Research Institute, Tokyo 104 0045, Japan
    Clin Cancer Res 8:2570-5. 2002
    ..The aim of this study was to determine the relationship of galectin-3 expression to clinicopathological findings and patient prognosis in ductal adenocarcinoma of the pancreas...
  90. ncbi request reprint Carcinoid tumor arising in a duplication cyst of the duodenum
    Hiroaki Hata
    Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan
    Pathol Int 56:272-8. 2006
    ....
  91. ncbi request reprint Dysadherin overexpression in pancreatic ductal adenocarcinoma reflects tumor aggressiveness: relationship to e-cadherin expression
    Takeshi Shimamura
    Pathology Division, National Cancer Center Research Institute, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    J Clin Oncol 21:659-67. 2003
    ..The aim of this study was to investigate the clinical significance of dysadherin expression and the relationship between dysadherin expression and E-cadherin expression in pancreatic ductal adenocarcinoma...
  92. ncbi request reprint Phosphoglyceride crystal deposition disease presenting as multiple paragastric masses
    Shinichi Yachida
    Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan
    Dig Dis Sci 47:1413-8. 2002