Research Topics
| Tadahiko ShienSummaryAffiliation: National Cancer Center Country: Japan Publications
| Collaborators
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Detail Information
Publications
Usefulness of preoperative multidetector-row computed tomography in evaluating the extent of invasive lobular carcinoma in patients with or without neoadjuvant chemotherapyTadahiko Shien
Division of Breast Surgery, National Cancer Center Hospital, 1 1 5 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
Breast Cancer 16:30-6. 2009..The present study was conducted to assess the clinical usefulness of multidetector-row CT (MDCT) in determining the extent of invasive lobular carcinoma (ILC) and especially the extent of residual tumor after neoadjuvant chemotherapy (NAC)...
Comparison among different classification systems regarding the pathological response of preoperative chemotherapy in relation to the long-term outcomeTadahiko Shien
Department of Breast Surgery, National Cancer Center Hospital, Tokyo, Japan
Breast Cancer Res Treat 113:307-13. 2009..All three classifications analyzed were considered inadequate as the prognostic marker of the long-term outcome after NAC and further studies are warranted to optimize the prediction...
21-Gene expression profile assay on core needle biopsies predicts responses to neoadjuvant endocrine therapy in breast cancer patientsSadako Akashi-Tanaka
Division of Breast Surgery, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo 104 0045, Japan
Breast 18:171-4. 2009..84% and 73%, respectively). These results suggest that RS predicts responses to NAET with tamoxifen or anastrozole. Because this pilot study examined a small sample size, these results should be validated in larger studies...
Clinicopathological features of tumors as predictors of the efficacy of primary neoadjuvant chemotherapy for operable breast cancerTadahiko Shien
Department of Surgery, National Cancer Center Hospital, Tokyo, Japan
World J Surg 33:44-51. 2009..Clinicopathological markers that predict patient response to NC are needed to individualize treatment...
Evaluation of axillary status in patients with breast cancer using thin-section CTTadahiko Shien
Division of Surgical Oncology, National Cancer Center Hospital, Tokyo, Japan
Int J Clin Oncol 13:314-9. 2008..We evaluated on the efficacy of preoperative axillary staging using contrast-enhanced computed tomography (CE-CT)...
Primary tumor resection improves the survival of younger patients with metastatic breast cancerTadahiko Shien
Department of Breast Surgery, National Cancer Center Hospital, Okayama, Japan
Oncol Rep 21:827-32. 2009..Prospective studies are required to validate these findings and evaluate the impact of surgical intervention...
Clinical efficacy of S-1 in pretreated metastatic breast cancer patientsTadahiko Shien
Division of Surgical Oncology, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
Jpn J Clin Oncol 38:172-5. 2008..S-1, an oral fluoropyrimidine carbamate, is an active and well-tolerated agent against solid cancer. However, the clinical efficacy of S-1 in patients with metastatic breast cancer has not been determined...
Whole-breast volume perfusion images using 256-row multislice computed tomography: visualization of lesions with ductal spreadSadako Akashi-Tanaka
Department of Breast Surgery, National Cancer Center Hospital, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo, 104 0045, Japan
Breast Cancer 16:62-7. 2009....
Primary small cell carcinoma of the breastTakashi Hojo
Breast Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
Breast Cancer 16:68-71. 2009..Therefore, the best therapy for primary small cell carcinoma of the breast may be surgery followed by adjuvant therapy similar to that recommended for small cell lung carcinoma...
Brain metastases after achieving local pathological complete responses with neoadjuvant chemotherapyShunsuke Tsukamoto
Breast Surgery Division, National Cancer Center Hospital, Tokyo, Japan
Breast Cancer 14:420-4. 2007..When primary breast tumors are locally advanced, it may be worthwhile to rule out brain metastases even if pCR is obtained after NAC...
Favorable outcome in patients with breast cancer in the presence of pathological response after neoadjuvant endocrine therapySadako Akashi-Tanaka
Division of Breast Surgery, National Cancer Center Hospital, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo 104 0045, Japan
Breast 16:482-8. 2007..Multivariate analysis of relapse-free survival indicated that pathological response was independent. Therefore, pathological response may be a favorable prognostic factor after NAET...
Diagnosis of complete response to neoadjuvant chemotherapy using diagnostic imaging in primary breast cancer patientsTakashi Kanazawa
Division of Surgical Oncology, National Cancer Center Hospital, Tokyo, Japan
Breast J 11:311-6. 2005..The evaluation of CR by CT was significantly indicative of pCR. The positive predictive value, however, was not large enough to avoid surgical treatment. Further studies will be needed to establish a diagnosis of pCR...
Clinical and pathological features of intracystic papillary carcinoma of the breastTomonori Akagi
Division of Breast Surgery, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
Surg Today 39:5-8. 2009..To evaluate the clinicopathological features of intracystic papillary carcinoma (ICPC), which have not been established given its rarity and lack of standard diagnostic criteria...
