Shizuka Sasazuki

Summary

Affiliation: National Cancer Center
Country: Japan

Publications

  1. pmc Plasma vitamin D and risk of colorectal cancer: the Japan Public Health Center-Based Prospective Study
    T Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Br J Cancer 97:446-51. 2007
  2. pmc Public awareness of risk factors for cancer among the Japanese general population: a population-based survey
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    BMC Public Health 6:2. 2006
  3. doi request reprint Plasma tea polyphenols and gastric cancer risk: a case-control study nested in a large population-based prospective study in Japan
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Epidemiol Biomarkers Prev 17:343-51. 2008
  4. doi request reprint Protective effect of vitamin C on oxidative stress: a randomized controlled trial
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Int J Vitam Nutr Res 78:121-8. 2008
  5. ncbi request reprint Effect of vitamin C on common cold: randomized controlled trial
    S Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Eur J Clin Nutr 60:9-17. 2006
  6. ncbi request reprint Green tea consumption and subsequent risk of gastric cancer by subsite: the JPHC Study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1, Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Causes Control 15:483-91. 2004
  7. ncbi request reprint Effect of Helicobacter pylori infection combined with CagA and pepsinogen status on gastric cancer development among Japanese men and women: a nested case-control study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 15:1341-7. 2006
  8. ncbi request reprint Plasma levels of C-reactive protein and serum amyloid A and gastric cancer in a nested case-control study: Japan Public Health Center-based prospective study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Carcinogenesis 31:712-8. 2010
  9. ncbi request reprint Female reproductive factors and the risk of gastric cancer in a large-scale population-based cohort study in Japan (JPHC study)
    Christina Persson
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 17:345-53. 2008
  10. doi request reprint Alcohol and risk of lung cancer among Japanese men: data from a large-scale population-based cohort study, the JPHC study
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Causes Control 19:1095-102. 2008

Collaborators

Detail Information

Publications107 found, 100 shown here

  1. pmc Plasma vitamin D and risk of colorectal cancer: the Japan Public Health Center-Based Prospective Study
    T Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Br J Cancer 97:446-51. 2007
    ..6; 95% confidence interval (CI), 1.0-20) and women (OR, 2.7, 95% CI, 0.94-7.6), compared with the combined category of the other quartiles. Our results suggest that a low level of plasma 25(OH)D may increase the risk of rectal cancer...
  2. pmc Public awareness of risk factors for cancer among the Japanese general population: a population-based survey
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    BMC Public Health 6:2. 2006
    ..The present study aimed to provide information on awareness of the attributable fraction of cancer causes among the Japanese general population...
  3. doi request reprint Plasma tea polyphenols and gastric cancer risk: a case-control study nested in a large population-based prospective study in Japan
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Epidemiol Biomarkers Prev 17:343-51. 2008
    ..02). Cigarette smoking was suggested to play a role as an effect modifier, which explains in part the different patterns observed by gender...
  4. doi request reprint Protective effect of vitamin C on oxidative stress: a randomized controlled trial
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Int J Vitam Nutr Res 78:121-8. 2008
    ..Although a number of reports regarding the role of reactive oxygen species (ROS) as the first step in cancer induction exist, few studies have investigated how vitamin C influences ROS in human plasma...
  5. ncbi request reprint Effect of vitamin C on common cold: randomized controlled trial
    S Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Eur J Clin Nutr 60:9-17. 2006
    ..To investigate the relationship between the common cold and vitamin C supplementation...
  6. ncbi request reprint Green tea consumption and subsequent risk of gastric cancer by subsite: the JPHC Study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1, Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Causes Control 15:483-91. 2004
    ..To investigate the relationship between green tea consumption and subsequent risk of gastric cancer at different anatomical subsites in a population-based prospective study...
  7. ncbi request reprint Effect of Helicobacter pylori infection combined with CagA and pepsinogen status on gastric cancer development among Japanese men and women: a nested case-control study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 15:1341-7. 2006
    ..Although accumulating evidence suggests that Helicobacter pylori plays a role in gastric carcinogenesis, the magnitude of the risk remains uncertain...
  8. ncbi request reprint Plasma levels of C-reactive protein and serum amyloid A and gastric cancer in a nested case-control study: Japan Public Health Center-based prospective study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Carcinogenesis 31:712-8. 2010
    ..005). In conclusion, our results suggest that those who react strongly to inflammation or who have a high host immune response, as reflected by extremely elevated plasma levels of CRP and SAA, are at a high risk to develop gastric cancer...
  9. ncbi request reprint Female reproductive factors and the risk of gastric cancer in a large-scale population-based cohort study in Japan (JPHC study)
    Christina Persson
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 17:345-53. 2008
    ..Although early estrogen exposure may have some protective effect, female reproductive factors may have no substantial influence on gastric cancer development...
  10. doi request reprint Alcohol and risk of lung cancer among Japanese men: data from a large-scale population-based cohort study, the JPHC study
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Causes Control 19:1095-102. 2008
    ..Here, we investigated the association between alcohol consumption and lung cancer incidence...
  11. ncbi request reprint Daily total physical activity level and total cancer risk in men and women: results from a large-scale population-based cohort study in Japan
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Epidemiol 168:391-403. 2008
    ..By site, decreased risks were observed for cancers of the colon, liver, and pancreas in men and for cancer of the stomach in women. Increased daily physical activity may be beneficial in preventing cancer in a relatively lean population...
  12. doi request reprint Combined impact of five lifestyle factors and subsequent risk of cancer: the Japan Public Health Center Study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Prev Med 54:112-6. 2012
    ..To evaluate whether 5 combined healthy lifestyle factors (not smoking, moderate drinking, eating minimum salt-preserved foods, being physically active, and having appropriate body mass index) are associated with reduced risk of cancer...
  13. doi request reprint 10-Year risk of colorectal cancer: development and validation of a prediction model in middle-aged Japanese men
    Enbo Ma
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Epidemiol 34:534-41. 2010
    ..As fewer studies on cancer risk prediction were seen so far, we initially developed an assessment tool with synthesizing key information from a variety of CRC risk factors through a large population-based cohort study...
  14. ncbi request reprint Body mass index and subsequent risk of kidney cancer: a prospective cohort study in Japan
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 20:466-72. 2010
    ..Herein, we investigate the association between body mass index (BMI) and kidney cancer risk in Japanese persons, a relatively lean population...
  15. ncbi request reprint Dietary calcium, vitamin D, and the risk of colorectal cancer
    Junko Ishihara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Clin Nutr 88:1576-83. 2008
    ..Calcium and vitamin D have a potential protective effect against colorectal cancer...
  16. doi request reprint Plasma isoflavone concentrations are not associated with gastric cancer risk among Japanese men and women
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Nutr 143:1293-8. 2013
    ..We found no association of plasma isoflavone concentrations with gastric cancer risk. Our data support the previously observed null association between isoflavone intake and gastric cancer risk...
  17. ncbi request reprint Zinc and heme iron intakes and risk of colorectal cancer: a population-based prospective cohort study in Japan
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Clin Nutr 96:864-73. 2012
    ..However, all of the studies on the association between zinc and heme iron intakes and colorectal cancer have been conducted in Western populations...
  18. doi request reprint Impact of alcohol intake on total mortality and mortality from major causes in Japan: a pooled analysis of six large-scale cohort studies
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Epidemiol Community Health 66:448-56. 2012
    ....
  19. doi request reprint Dairy product, saturated fatty acid, and calcium intake and prostate cancer in a prospective cohort of Japanese men
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 17:930-7. 2008
    ..62 (1.15-2.29) and 1.53 (1.07-2.20), respectively. In conclusion, our results suggest that the intake of dairy products may be associated with an increased risk of prostate cancer...
  20. ncbi request reprint Fruit and vegetable consumption and squamous cell carcinoma of the esophagus in Japan: the JPHC study
    Taiki Yamaji
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 123:1935-40. 2008
    ..Finally, cruciferous vegetables deserve further investigation as foods possibly effective in the prevention of esophageal SCC...
  21. doi request reprint Plasma tea polyphenol levels and subsequent risk of breast cancer among Japanese women: a nested case-control study
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Breast Cancer Res Treat 124:827-34. 2010
    ..This nested case-control study found no overall association between plasma tea polyphenols and the risk of breast cancer in Japan...
  22. pmc Use of vitamin supplements and risk of total cancer and cardiovascular disease among the Japanese general population: a population-based survey
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo 104 0045, Japan
    BMC Public Health 11:540. 2011
    ..We examined whether vitamin supplement use patterns affect cancer and CVD risk in a population-based cohort study in Japan...
  23. doi request reprint Coffee, green tea, and caffeine consumption and subsequent risk of bladder cancer in relation to smoking status: a prospective study in Japan
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer Sci 100:294-91. 2009
    ..15–3.66), respectively. In conclusion, cigarette smoking was confirmed as a risk factor for bladder cancer. Coffee and caffeine may be associated with an increased bladder cancer risk in never or former smokers among Japanese men...
  24. ncbi request reprint Association between lung cancer incidence and family history of lung cancer: data from a large-scale population-based cohort study, the JPHC study
    Jun ichi Nitadori
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045 Japan
    Chest 130:968-75. 2006
    ..To clarify the possibility of a hereditary predisposition to lung cancer, we investigated the association between a family history of lung cancer and subsequent risk of lung cancer in a large-scale, population-based cohort study...
  25. doi request reprint Body weight at age 20 years, subsequent weight change and breast cancer risk defined by estrogen and progesterone receptor status--the Japan public health center-based prospective study
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 129:1214-24. 2011
    ..50-3.34)]. Low BMI at age 20 years was substantially associated with an increased risk of breast cancer. In contrast, high recent BMI and subsequent BMI gain from age 20 were associated with increased risk of postmenopausal ER+PR+ tumors...
  26. doi request reprint Leisure-time physical activity and breast cancer risk defined by estrogen and progesterone receptor status--the Japan Public Health Center-based Prospective Study
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo, 104 0045, Japan
    Prev Med 52:227-33. 2011
    ..The study aims to investigate the association between leisure-time physical activity and breast cancer risk in consideration of tumor estrogen-receptor/progesterone-receptor status...
  27. doi request reprint Plasma isoflavone level and subsequent risk of breast cancer among Japanese women: a nested case-control study from the Japan Public Health Center-based prospective study group
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    J Clin Oncol 26:1677-83. 2008
    ..Nevertheless, no prospective study from Asia has assessed blood or urine levels as biomarkers of isoflavone intake...
  28. ncbi request reprint Coping behaviors and suicide in the middle-aged and older Japanese general population: the Japan Public Health Center-based Prospective Study
    Thomas Svensson
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan Department of Neuropsychiatry, Keio University School of Medicine, Shinjuku ku, Tokyo, Japan
    Ann Epidemiol 24:199-205. 2014
    ..Cross-sectional studies have shown an association between different coping styles and suicidal behavior. It is unknown whether there is any prospective association between coping behaviors and suicide in the general population...
  29. ncbi request reprint Diabetes mellitus and cancer risk: pooled analysis of eight cohort studies in Japan
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Sci 104:1499-507. 2013
    ..Studies continuously investigating the risk factors for diabetes are also important...
  30. doi request reprint Effect of alcohol consumption, cigarette smoking and flushing response on esophageal cancer risk: a population-based cohort study (JPHC study)
    Seiji Ishiguro
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Lett 275:240-6. 2009
    ..10-5.51). Strong effect modification was detected in heavy smokers. Our results suggest that heavy alcohol consumption together with heavy smoking may increase the risk of ESCC particularly in individuals with the flushing response...
  31. doi request reprint Long-term dietary cadmium intake and cancer incidence
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Epidemiology 23:368-76. 2012
    ..However, data from general populations are sparse. We prospectively examined the association between cadmium exposure and incidence of cancer in a Japanese population with a relatively high dietary intake of cadmium...
  32. doi request reprint Isoflavone intake and risk of gastric cancer: a population-based prospective cohort study in Japan
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Clin Nutr 95:147-54. 2012
    ..The association with gastric cancer might differ between isoflavones and soy foods, and research on the effects of isoflavone intake alone on gastric cancer is needed...
  33. doi request reprint Coffee consumption and risk of endometrial cancer: a prospective study in Japan
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 123:2406-10. 2008
    ..Coffee consumption may be associated with a decreased risk of endometrial cancer...
  34. doi request reprint Plasma levels of carotenoids, retinol and tocopherol and the risk of gastric cancer in Japan: a nested case-control study
    Christina Persson
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo ku 104 0045, Tokyo, Japan
    Carcinogenesis 29:1042-8. 2008
    ..Our findings suggest that those who have very low plasma levels of alpha-carotene and beta-carotene are at a higher risk of gastric cancer...
  35. ncbi request reprint Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population
    Shinobu Ikeda
    Department of Molecular Epidemiology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan
    Am J Gastroenterol 103:1476-87. 2008
    ..To investigate the association between polymorphisms and gastrointestinal (gastric and colorectal) cancer, we performed a hospital-based case-control study in Japan...
  36. ncbi request reprint Impact of five modifiable lifestyle habits on the probability of cancer occurrence in a Japanese population-based cohort: results from the JPHC study
    Hadrien Charvat
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Prev Med 57:685-9. 2013
    ..The present work aims to provide 10-year estimates of the probability of cancer occurrence in the Japanese population based on age, sex, and the pattern of adherence to five healthy lifestyle habits...
  37. ncbi request reprint Colorectal cancer screening using fecal occult blood test and subsequent risk of colorectal cancer: a prospective cohort study in Japan
    Kyung Jae Lee
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Detect Prev 31:3-11. 2007
    ..To investigate prospectively the association between colorectal cancer screening and subsequent risk of colorectal cancer death in a large-scale population-based cohort study (the JPHC study) with a 13-year follow-up period in Japan...
  38. ncbi request reprint Clinical significance of IgG antibody titer against Helicobacter pylori
    Masayuki Tatemichi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Helicobacter 14:231-6. 2009
    ..We clarified the clinical significance of measurement of IgG antibody titers against Helicobacter pylori using data from a nested case-control study from a large-scale cohort study in Japan...
  39. doi request reprint Validity of self-reported cancer among a Japanese population: recent results from a population-based prospective study in Japan (JPHC Study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol 35:250-3. 2011
    ..Self-reported diagnoses of cancer do not provide sufficient accuracy for the detection and classification of incident cancers. Our findings may be extrapolated to other Japanese populations...
  40. ncbi request reprint Plasma folate and risk of colorectal cancer in a nested case-control study: the Japan Public Health Center-based prospective study
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer Causes Control 19:67-74. 2008
    ..We investigated the association between plasma folate and the risk of colorectal cancer in a nested case-control study...
  41. ncbi request reprint Reproductive factors, exogenous female hormone use and colorectal cancer risk: the Japan Public Health Center-based Prospective Study
    Munira Akhter
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 17:515-24. 2008
    ..59). In contrast, no statistically significant association was found for rectal cancer. These findings suggest that late age at first birth is associated with a reduced risk of colon cancer in postmenopausal Japanese women...
  42. ncbi request reprint Daily total physical activity level and premature death in men and women: results from a large-scale population-based cohort study in Japan (JPHC study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 18:522-30. 2008
    ..We prospectively examined the association between daily total physical activity level (METs/day) and subsequent risk of all-cause mortality and mortalities from cancer, heart disease, and cerebrovascular disease...
  43. pmc Body mass index and mortality from all causes and major causes in Japanese: results of a pooled analysis of 7 large-scale cohort studies
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Epidemiol 21:417-30. 2011
    ....
  44. doi request reprint Plasma isoflavones and the risk of lung cancer in women: a nested case-control study in Japan
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, 104 0045 Japan
    Cancer Epidemiol Biomarkers Prev 20:419-27. 2011
    ....
  45. ncbi request reprint Fruit and vegetable intake and breast cancer risk defined by estrogen and progesterone receptor status: the Japan Public Health Center-based Prospective Study
    Reiko Suzuki
    Division of Medical Nutrition, Department of Medical Healthcare, Tokyo Healthcare University, 3 11 3 Setagaya, Setagaya Ku, Tokyo, Japan
    Cancer Causes Control 24:2117-28. 2013
    ..Epidemiological evidence for the impact of fruit and vegetable intake on breast cancer risk among the Japanese populations is scarce...
  46. pmc Green tea drinking and subsequent risk of breast cancer in a population-based cohort of Japanese women
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Breast Cancer Res 12:R88. 2010
    ....
  47. doi request reprint Green tea consumption and gastric cancer risk: an evaluation based on a systematic review of epidemiologic evidence among the Japanese population
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji Chuo ku, Tokyo 104 0045 Japan
    Jpn J Clin Oncol 42:335-46. 2012
    ..We evaluated the association between green tea consumption and risk for gastric cancer risk among the Japanese population based on a systematic review of epidemiologic evidence...
  48. doi request reprint Alcohol drinking and primary liver cancer: a pooled analysis of four Japanese cohort studies
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 130:2645-53. 2012
    ..0 g alcohol/day) in men and (2) moderate drinking (≥23.0 g alcohol/day) in women may reduce the risk of primary liver cancer...
  49. ncbi request reprint Alcohol consumption-associated breast cancer incidence and potential effect modifiers: the Japan Public Health Center-based Prospective Study
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Int J Cancer 127:685-95. 2010
    ..15). Excessive alcohol intake was associated with an increase in the risk of breast cancer in this population. There was no statistical evidence for effect modification...
  50. ncbi request reprint Consumption of sodium and salted foods in relation to cancer and cardiovascular disease: the Japan Public Health Center-based Prospective Study
    Ribeka Takachi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Clin Nutr 91:456-64. 2010
    ....
  51. doi request reprint High dietary intake of magnesium may decrease risk of colorectal cancer in Japanese men
    Enbo Ma
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Nutr 140:779-85. 2010
    ..There were no significant associations between magnesium intake and cancer risk in women. Higher dietary intake of magnesium may decrease the risk of CRC in Japanese men...
  52. ncbi request reprint Plasma testosterone and sex hormone-binding globulin concentrations and the risk of prostate cancer among Japanese men: a nested case-control study
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Sci 101:2652-7. 2010
    ..In conclusion, in this nested case-control study, concentrations of circulating total testosterone, free testosterone or SHBG were not strongly associated with a risk for total prostate cancer...
  53. ncbi request reprint Dietary soy and isoflavone intake and risk of colorectal cancer in the Japan public health center-based prospective study
    Munira Akhter
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Epidemiol Biomarkers Prev 17:2128-35. 2008
    ..These findings suggest that the intake of isoflavones, miso soup, and soy food has no substantial effect on the risk of colorectal cancer in Japanese men and women...
  54. ncbi request reprint Association between polymorphisms in glutathione S-transferase Mu3 and IgG titer levels in serum against Helicobacter pylori
    Masayuki Tatemichi
    Department of Hygiene and Preventive Medicine, School of Medicine, Showa University, Shinagawa ku, Tokyo, Japan
    J Hum Genet 54:557-63. 2009
    ..pylori. GST-M3 activity is possibly involved in protection against mucosal atrophy caused by H. pylori as the levels of IgG titer and PGI are linked to mucosal status...
  55. doi request reprint Different etiological role of Helicobacter pylori (Hp) infection in carcinogenesis between differentiated and undifferentiated gastric cancers: a nested case-control study using IgG titer against Hp surface antigen
    Masayuki Tatemichi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Acta Oncol 47:360-5. 2008
    ....
  56. doi request reprint Alcohol and smoking and subsequent risk of prostate cancer in Japanese men: the Japan Public Health Center-based prospective study
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 134:971-8. 2014
    ..In conclusion, abstinence from alcohol and prohibition of smoking might be important factors in the prevention of advanced prostate cancer...
  57. ncbi request reprint Plasma C-reactive protein and risk of colorectal cancer in a nested case-control study: Japan Public Health Center-based prospective study
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 15:690-5. 2006
    ..In conclusion, plasma levels of C-reactive protein were associated with a subsequent risk of colon cancer. Inflammation may be involved at the early stage of colon tumor growth...
  58. pmc Dietary arsenic intake and subsequent risk of cancer: the Japan Public Health Center-based (JPHC) Prospective Study
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Causes Control 24:1403-15. 2013
    ..However, the effects of arsenic exposure from food on health are still unknown. We researched to examine the association between arsenic exposure from food and incidence of cancer in a Japanese population...
  59. ncbi request reprint Physical activity and risk of colorectal cancer in Japanese men and women: the Japan Public Health Center-based prospective study
    Kyung Jae Lee
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo, Japan
    Cancer Causes Control 18:199-209. 2007
    ....
  60. ncbi request reprint Consumption of n-3 fatty acids and fish reduces risk of hepatocellular carcinoma
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tsukiji, Chuo ku Tokyo, Japan
    Gastroenterology 142:1468-75. 2012
    ..Although consumption of fish and n-3 PUFA has been reported to protect against the development of some types of cancer, little is known about its association with hepatocellular carcinoma (HCC)...
  61. doi request reprint Seaweed consumption and the risk of thyroid cancer in women: the Japan Public Health Center-based Prospective Study
    Takehiro Michikawa
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji Chuo ku, Tokyo, Japan
    Eur J Cancer Prev 21:254-60. 2012
    ..91, 95% CI: 0.44-1.91; trend P=0.76). This study identified a positive association between seaweed consumption and the risk of thyroid cancer (especially for papillary carcinoma) in postmenopausal women...
  62. ncbi request reprint Red meat intake may increase the risk of colon cancer in Japanese, a population with relatively low red meat consumption
    Ribeka Takachi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Asia Pac J Clin Nutr 20:603-12. 2011
    ..In conclusion, red meat intake may modestly increase the risk of colon cancer in middle-aged Japanese, although the highest quintile of red meat consumption could be considered moderate by Western standards...
  63. ncbi request reprint Body mass index, physical activity and the risk of pancreatic cancer in relation to smoking status and history of diabetes: a large-scale population-based cohort study in Japan--the JPHC study
    Juhua Luo
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Cancer Causes Control 18:603-12. 2007
    ..In particular, we explored how these effects were influenced by smoking status and a history of diabetes...
  64. pmc Plasma organochlorines and subsequent risk of prostate cancer in Japanese men: a nested case-control study
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Environ Health Perspect 118:659-65. 2010
    ..To our knowledge, this is the first prospective study to investigate the association between blood levels of organochlorines and prostate cancer risk...
  65. pmc Validity of a self-administered food frequency questionnaire for middle-aged urban cancer screenees: comparison with 4-day weighed dietary records
    Ribeka Takachi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Epidemiol 21:447-58. 2011
    ..We examined the validity of ranking individuals according to level of dietary consumption, as estimated by this FFQ, among an urban population in Japan...
  66. ncbi request reprint Passive smoking and lung cancer in Japanese non-smoking women: a prospective study
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji Chuo ku, Tokyo, Japan
    Int J Cancer 122:653-7. 2008
    ..93, 95% CI 0.88-4.23). These findings confirm that passive smoking is a risk factor for lung cancer, especially for adenocarcinoma among Japanese women...
  67. ncbi request reprint Coffee consumption and risk of colorectal cancer in a population-based prospective cohort of Japanese men and women
    Kyung Jae Lee
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 121:1312-8. 2007
    ..These findings suggest that coffee consumption may lower the risk of colon cancer among Japanese women...
  68. doi request reprint Intake of n-3 and n-6 polyunsaturated fatty acids and development of colorectal cancer by subsite: Japan Public Health Center-based prospective study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 129:1718-29. 2011
    ..Our results suggest that intake of marine n-3 polyunsaturated fatty acids may be inversely related to the risk of cancer in the proximal site of the large bowel...
  69. doi request reprint Green tea and coffee consumption and its association with thyroid cancer risk: a population-based cohort study in Japan
    Takehiro Michikawa
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Cancer Causes Control 22:985-93. 2011
    ..We examined green tea and coffee consumption in association with thyroid cancer risk in a general Japanese population...
  70. ncbi request reprint Plasma organochlorine levels and subsequent risk of breast cancer among Japanese women: a nested case-control study
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Sci Total Environ 402:176-83. 2008
    ..Our data do not support the hypothesis that plasma levels of p,p'-DDT, p,p'-DDE, HCB, and beta-HCH are associated with an overall increased risk of breast cancer among Japanese women...
  71. ncbi request reprint Green tea and coffee intake and risk of pancreatic cancer in a large-scale, population-based cohort study in Japan (JPHC study)
    Juhua Luo
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 16:542-8. 2007
    ..In conclusion, our findings support the idea that green tea or coffee consumption does not have a substantial impact on pancreatic cancer risk in general...
  72. ncbi request reprint Atrophic gastritis, Helicobacter pylori, and colorectal cancer risk: a case-control study
    Ai Machida-Montani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Helicobacter 12:328-32. 2007
    ..However, the correlation between H. pylori and colorectal cancer (CRC) is controversial. The aim of this study was to examine the correlation between H. pylori, serum gastrin level, and atrophic gastritis with CRC...
  73. doi request reprint Methionine synthase A2756G polymorphism interacts with alcohol and folate intake to influence the risk of colorectal adenoma
    Taiki Yamaji
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Epidemiol Biomarkers Prev 18:267-74. 2009
    ..Our findings add to increasing evidence that DNA methylation plays an important role even at an early stage of colorectal carcinogenesis...
  74. doi request reprint Impact of metabolic factors on subsequent cancer risk: results from a large-scale population-based cohort study in Japan
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, International Medical Center of Japan, Tokyo, Japan
    Eur J Cancer Prev 18:240-7. 2009
    ..21-2.55). Metabolic factors in the aggregate may have little impact on total cancer risk in the Japanese population, although the association between specific components and specific cancers suggests an etiologic link between them...
  75. ncbi request reprint Visceral fat volume and the prevalence of colorectal adenoma
    Taiki Yamaji
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Epidemiol 170:1502-11. 2009
    ..The mechanisms of this potential association between visceral adiposity and colorectal carcinogenesis warrant further investigation...
  76. ncbi request reprint Bowel movement, state of stool, and subsequent risk for colorectal cancer: the Japan public health center-based prospective study
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 16:888-94. 2006
    ..Evidence about whether irregular bowel movements or unusual stool conditions are associated with colorectal cancer is still inconsistent...
  77. ncbi request reprint Soy product and isoflavone consumption in relation to prostate cancer in Japanese men
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo 104 0045 Japan
    Cancer Epidemiol Biomarkers Prev 16:538-45. 2007
    ..52 [95% confidence interval (95% CI), 0.30-0.90], 0.50 (95% CI, 0.28-0.88), and 0.52 (95% CI, 0.29-0.90), respectively. In conclusion, we found that isoflavone intake was associated with a decreased risk of localized prostate cancer...
  78. ncbi request reprint Green tea consumption and prostate cancer risk in Japanese men: a prospective study
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Epidemiol 167:71-7. 2008
    ..52 (95% confidence interval: 0.28, 0.96) for men drinking 5 or more cups/day compared with less than 1 cup/day (p(trend) = 0.01). Green tea may be associated with a decreased risk of advanced prostate cancer...
  79. doi request reprint Plasma isoflavones and subsequent risk of prostate cancer in a nested case-control study: the Japan Public Health Center
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji Chuo ku Tokyo 104 0045 Japan
    J Clin Oncol 26:5923-9. 2008
    ..Given the preventive effects of isoflavones on carcinogenesis in the prostate in many nonhuman studies and the high consumption of isoflavones in Japanese, this low incidence may be partly due to the effects of soy...
  80. ncbi request reprint Low intake of vitamin B-6 is associated with increased risk of colorectal cancer in Japanese men
    Junko Ishihara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    J Nutr 137:1808-14. 2007
    ..Our results support previous evidence that low vitamin B-6 intake is associated with an increased risk of colorectal cancer. In particular, a higher intake of vitamin B-6 appears beneficial in men with higher alcohol intake...
  81. ncbi request reprint Prospective study of three major dietary patterns and risk of gastric cancer in Japan
    Mi Kyung Kim
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 110:435-42. 2004
    ..These associations persisted in histologic subtypes. Our findings support the idea that the healthy pattern decreased the risk of gastric cancer among females, while the traditional pattern increased the risk in both genders...
  82. ncbi request reprint Diabetes mellitus and the risk of cancer: results from a large-scale population-based cohort study in Japan
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Arch Intern Med 166:1871-7. 2006
    ..An association between diabetes mellitus (DM) and cancer has long been speculated, but no conclusive evidence has been obtained...
  83. ncbi request reprint Body size and risk for breast cancer in relation to estrogen and progesterone receptor status in Japan
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 17:304-12. 2007
    ..The aim of this study is to examine the association of height, weight, and body mass index (BMI) with breast cancer and its hormone receptor-defined subtype in a low-risk population...
  84. doi request reprint Interaction between adiponectin and leptin influences the risk of colorectal adenoma
    Taiki Yamaji
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Res 70:5430-7. 2010
    ..Our findings provide the first epidemiologic evidence for interactive effects of adiponectin and leptin in the early stage of colorectal tumorigenesis, distinct from their involvement in insulin resistance...
  85. ncbi request reprint Dietary fiber intake and subsequent risk of colorectal cancer: the Japan Public Health Center-based prospective study
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 119:1475-80. 2006
    ..Q5), 2.3; 95% confidence interval, 1.0-5.2). In conclusion, although a minor effect cannot be ruled out, the results did not support a hypothesis of a dose-dependent protective effect of dietary fiber intake against colorectal cancer...
  86. ncbi request reprint Cigarette smoking and subsequent risk of lung cancer by histologic type in middle-aged Japanese men and women: the JPHC study
    Tomotaka Sobue
    Cancer Information and Epidemiology Division, National Cancer Center Research Institute, Tokyo, Japan
    Int J Cancer 99:245-51. 2002
    ....
  87. ncbi request reprint Effect of five-year supplementation of vitamin C on serum vitamin C concentration and consumption of vegetables and fruits in middle-aged Japanese: a randomized controlled trial
    Mi Kyung Kim
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Chiba, Japan
    J Am Coll Nutr 22:208-16. 2003
    ..This study was aimed at evaluating the effect of long-term vitamin C supplementation on serum and dietary vitamin C and identifying the factors associated with change in serum concentration...
  88. doi request reprint Isoflavone intake and risk of lung cancer: a prospective cohort study in Japan
    Taichi Shimazu
    Research Center for Cancer Prevention and Screening, National Cancer Center Tokyo Japan
    Am J Clin Nutr 91:722-8. 2010
    ..Moreover, no prospective study has addressed this association in men...
  89. doi request reprint Alcohol drinking and colorectal cancer in Japanese: a pooled analysis of results from five cohort studies
    Tetsuya Mizoue
    Department of Epidemiology and International Health, Research Institute, International Medical Center of Japan, Tokyo, Japan
    Am J Epidemiol 167:1397-406. 2008
    ..An alcohol-colorectal cancer association seems to be more apparent in Japanese than in Western populations. Whether this difference can be ascribed to genetic or environmental factors needs to be clarified...
  90. ncbi request reprint Plasma C-peptide, insulin-like growth factor-I, insulin-like growth factor binding proteins and risk of colorectal cancer in a nested case-control study: the Japan public health center-based prospective study
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 120:2007-12. 2007
    ..The results did not change when repeatedly analyzed by tumor invasion levels, tumor sites or follow-up periods. In conclusion, a higher plasma C-peptide may indicate a subsequent risk of colorectal cancer in Japanese men...
  91. ncbi request reprint Risk factors of biliary tract cancer in a large-scale population-based cohort study in Japan (JPHC study); with special focus on cholelithiasis, body mass index, and their effect modification
    Seiji Ishiguro
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer Causes Control 19:33-41. 2008
    ..Particular focus was placed on a history of cholelithiasis, body mass index (BMI), and their effect modification, and whether risk differs by cancer subsite, namely by gallbladder cancer and extrahepatic bile duct cancer...
  92. ncbi request reprint The effect of 5-year vitamin C supplementation on serum pepsinogen level and Helicobacter pylori infection
    Shizuka Sasazuki
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa 277 8577, Japan
    Cancer Sci 94:378-82. 2003
    ..25 for the low-dose group and - 0.13 for the high-dose group (P = 0.046). To conclude, vitamin C supplementation may protect against progression of gastric mucosal atrophy...
  93. ncbi request reprint Cigarette smoking, alcohol consumption and subsequent gastric cancer risk by subsite and histologic type
    Shizuka Sasazuki
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa City, Japan
    Int J Cancer 101:560-6. 2002
    ..Further studies with more cases are needed to detect a positive association between cigarette smoking or alcohol consumption and cardia cancer...
  94. ncbi request reprint Vegetables, fruit and risk of gastric cancer in Japan: a 10-year follow-up of the JPHC Study Cohort I
    Minatsu Kobayashi
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Japan
    Int J Cancer 102:39-44. 2002
    ..Although no striking differences in the association were seen between cardia and noncardia cancer, an inverse association was higher in differentiated rather than in undifferentiated types of gastric cancer...
  95. ncbi request reprint Risk factors for stomach cancer in Brazil (I): a case-control study among non-Japanese Brazilians in São Paulo
    Ines Nobuko Nishimoto
    Research Center, Hospital do Cancer A C Camargo, Sao Paulo, Brazil
    Jpn J Clin Oncol 32:277-83. 2002
    ..Nevertheless, there are no reports of analytical epidemiological study on stomach cancer in Brazil...
  96. ncbi request reprint Fruit and vegetable intake and risk of total cancer and cardiovascular disease: Japan Public Health Center-Based Prospective Study
    Ribeka Takachi
    Department of Clinical Epidemiology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Am J Epidemiol 167:59-70. 2008
    ..16) for vegetables. This prospective cohort study demonstrated that, in the Japanese population, consumption of fruit is associated with lower risk of CVD, whereas fruit or vegetables may not be associated with lower risk of total cancer...
  97. ncbi request reprint Risk factors for stomach cancer in Brazil (II): a case-control study among Japanese Brazilians in São Paulo
    Gerson Shigueaki Hamada
    Nikkei Disease Prevention Center, Santa Cruz Hospital, Sao Paulo, Brazil
    Jpn J Clin Oncol 32:284-90. 2002
    ..Although stomach cancer is the most frequent cancer among Japanese Brazilians, the risk factor of this cancer has not been investigated among them...
  98. ncbi request reprint Lack of long-term effect of vitamin C supplementation on blood pressure
    Mi Kyung Kim
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Japan
    Hypertension 40:797-803. 2002
    ..In conclusion, we observed no reduction in blood pressure with long-term moderate doses (500 mg/day) of vitamin C supplementation in a high-risk population for stomach cancer and stroke...
  99. ncbi request reprint Food/nutrient intake and risk of atrophic gastritis among the Helicobacter pylori-infected population of northeastern Japan
    Ai Montani
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, Kashiwa, Chiba 277 8577, Japan
    Cancer Sci 94:372-7. 2003
    ..From these results, it is suggested that the dietary habits of consumers of traditional Japanese foods may play a role in the development of atrophic gastritis after H. pylori infection...
  100. ncbi request reprint Association of Helicobacter pylori infection and environmental factors in non-cardia gastric cancer in Japan
    Ai Machida-Montani
    Epidemiology and Biostatistics Division, National Cancer Center Research Institute East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    Gastric Cancer 7:46-53. 2004
    ..pylori infection, and to investigate the effects of the interaction between environmental factors and H. pylori infection...
  101. ncbi request reprint Long-term vitamin C supplementation has no markedly favourable effect on serum lipids in middle-aged Japanese subjects
    Mi Kyung Kim
    Department of Preventive Medicine, The Catholic University of Korea, Seoul, Korea
    Br J Nutr 91:81-90. 2004
    ..However, our present results do not preclude the possibility that vitamin C supplementation may decrease triacylglycerol concentrations among women with hypertriacylglycerolaemia...