Research Topics
Genomes and GenesSpecies | Naruya SaitouSummaryAffiliation: National Institute of Genetics Country: Japan Publications
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Detail Information
Publications
The PNarec method for detection of ancient recombinations through phylogenetic network analysisNaruya Saitou
Division of Population Genetics, National Institute of Genetics, Mishima 411 8540, Japan
Mol Phylogenet Evol 66:507-14. 2013..2009. Mol. Phylogenet. Evol., 51, 465-471]. We present applications of this method, now named as "PNarec", to various virus sequences as well as HLA genes...
MISHIMA--a new method for high speed multiple alignment of nucleotide sequences of bacterial genome scale dataKirill Kryukov
Division of Population Genetics, National Institute of Genetics 1111 Yata, Mishima, 411 8540, Japan
BMC Bioinformatics 11:142. 2010..These approaches have performance problems when the number of sequences is large and when dealing with genome scale sequences...
Mosaic genealogy of the Mus musculus genome revealed by 21 nuclear genes from its three subspeciesYu Hua Liu
Division of Population Genetics, National Institute of Genetics, Mishima, Japan
Genes Genet Syst 83:77-88. 2008..Gene genealogies of Fut4 and Dfy loci also suggested existence of the gene flow between M. musculus and M. spicilegus or other distant species...
Relic of ancient recombinations in gibbon ABO blood group genes deciphered through phylogenetic network analysisTakashi Kitano
Division of Population Genetics, National Institute of Genetics, Yata, Mishima, Japan
Mol Phylogenet Evol 51:465-71. 2009..This establishes the coexistence of divergent allelic lineages of the ABO blood group gene for a long period in the ancestral gibbon species, and strengthens the non-neutral evolution for this gene...
Evolution of conserved non-coding sequences within the vertebrate Hox clusters through the two-round whole genome duplications revealed by phylogenetic footprinting analysisMasatoshi Matsunami
Department of Genetics, School of Life Science, The Graduate University for Advanced Studies Sokendai, Mishima, 411 8540, Japan
J Mol Evol 71:427-36. 2010..The authors also compared vertebrate CNSs with amphioxus CNSs within the Hox cluster, and found that two CNSs in the HoxA and HoxB clusters retain homology with amphioxus CNSs through the two-round whole genome duplications...
Evolutionary conservation of 5' upstream sequence of nine genes between human and great apesTakashi Kitano
Division of Population Genetics, National Institute of Genetics Mishima, Japan
Genes Genet Syst 80:225-32. 2005..17-1.76 x 10(-9)) of nucleotide substitutions for the corresponding 5' upstream regions in rodents (mouse/rat comparison). Thus the primate rate was lower than rodent rate also for the 5' upstream regions...
Evolutionary pattern of gene homogenization between primate-specific paralogs after human and macaque speciation using the 4-2-4 methodKiyoshi Ezawa
Division of Population Genetics, National Institute of Genetics, Mishima, Japan
Mol Biol Evol 27:2152-71. 2010..Patterns of the homogenization in the genomic alignments of human-macaque quartets indicate that gene conversion, rather than unequal crossing-over, is the major cause of the homogenization...
Evolutionary patterns of recently emerged animal duplogsKiyoshi Ezawa
Division of Population Genetics, National Institute of Genetics, Mishima, Japan
Genome Biol Evol 3:1119-35. 2011..The drift duplication has been producing duplicate copies at paces comparable with tandem duplications since the common ancestor of vertebrates, and it may have already operated in the common ancestor of bilateral animals...
Proceedings of the SMBE Tri-National Young Investigators' Workshop 2005. Genome-wide search of gene conversions in duplicated genes of mouse and ratKiyoshi Ezawa
Division of Population Genetics, National Institute of Genetics, Mishima, Japan
Mol Biol Evol 23:927-40. 2006..These findings will be useful to deepen the understanding of the roles of gene conversion...
Loss-of-function mutation in a repressor module of human-specifically activated enhancer HACNS1Kenta Sumiyama
Division of Population Genetics, National Institute of Genetics, Mishima, Japan
Mol Biol Evol 28:3005-7. 2011..This result infers that loss of function in the HACNS1 81-bp region, possibly via a BGC, played an important role in human-specific evolution...
Mitochondrial DNA genealogy of chimpanzees in the Nimba mountains and Bossou, West AfricaMakoto K Shimada
Division of Population Genetics, National Institute of Genetics, Mishima, Japan
Am J Primatol 64:261-75. 2004..This suggests that the Bossou-Nimba populations derived only recently from the common ancestral population of the West African chimpanzees, and did not pass through a bottleneck...
