Y Onishi

Summary

Affiliation: National Institute of Advanced Industrial Science and Technology
Country: Japan

Publications

  1. ncbi Rhythmic binding of Topoisomerase I impacts on the transcription of Bmal1 and circadian period
    Yoshiaki Onishi
    Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology, Higashi 1 1 1, Tsukuba 305 8566, Japan
    Nucleic Acids Res 40:9482-92. 2012
  2. ncbi Lycorine, a candidate for the control of period length in mammalian cells
    Yoshiaki Onishi
    Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology, Higashi, Tsukuba, Japan
    Cell Physiol Biochem 29:407-16. 2012
  3. ncbi The harmala alkaloid harmine is a modulator of circadian Bmal1 transcription
    Yoshiaki Onishi
    Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Higashi 1 1 1, Tsukuba 305 8566, Japan
    Biosci Rep 32:45-52. 2012
  4. ncbi HSG cells, a model in the submandibular clock
    Yoshiaki Onishi
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    Biosci Rep 31:57-62. 2011
  5. ncbi Rhythmic SAF-A binding underlies circadian transcription of the Bmal1 gene
    Yoshiaki Onishi
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology AIST, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Mol Cell Biol 28:3477-88. 2008
  6. ncbi Enhancer activity of HS2 of the human beta-LCR is modulated by distance from the key nucleosome
    Y Onishi
    Institute of Molecular and Cell Biology, AIST Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Nucleic Acids Res 29:3448-57. 2001
  7. ncbi Preparation and characterization of an anti-DNA monoclonal antibody showing size selectivity toward DNA fragments
    Yoshiaki Onishi
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Ibaraki, Japan
    Hybrid Hybridomics 23:311-7. 2004
  8. ncbi Interaction of NF-E2 in the human beta-globin locus control region before chromatin remodeling
    Yoshiaki Onishi
    Research Center for Glycoscience, National Institute of Advanced Industrial Science and Technology, AIST Tsukuba Central 6, 1 1 1 Higashi, Ibaraki 305 8566, Japan
    J Biol Chem 278:8163-71. 2003
  9. ncbi Biochemical screening of stable dinucleosomes using DNA fragments from a dinucleosome DNA library
    Megumi Kato
    Research Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan
    J Mol Biol 350:215-27. 2005
  10. ncbi Evolutionary conservation and functional synergism of curved DNA at the mouse epsilon- and other globin-gene promoters
    Chanane Wanapirak
    Research Center for Glycoscience, National Institute of Advanced Industrial Science and Technology, AIST Tsukuba Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan
    J Mol Evol 56:649-57. 2003

Collaborators

Detail Information

Publications18

  1. ncbi Rhythmic binding of Topoisomerase I impacts on the transcription of Bmal1 and circadian period
    Yoshiaki Onishi
    Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology, Higashi 1 1 1, Tsukuba 305 8566, Japan
    Nucleic Acids Res 40:9482-92. 2012
    ..These data indicate that Top1 modulates the chromatin structure of the Bmal1 promoter, regulates Bmal1 transcription and influences the circadian period...
  2. ncbi Lycorine, a candidate for the control of period length in mammalian cells
    Yoshiaki Onishi
    Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology, Higashi, Tsukuba, Japan
    Cell Physiol Biochem 29:407-16. 2012
    ..These data indicate that lycorine and lycoricidinol modulate Bmal1 transcription and the circadian period, and also suggest that Lycoris alkaloids are novel contributors to the control of period length in mammalian cells...
  3. ncbi The harmala alkaloid harmine is a modulator of circadian Bmal1 transcription
    Yoshiaki Onishi
    Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Higashi 1 1 1, Tsukuba 305 8566, Japan
    Biosci Rep 32:45-52. 2012
    ..These results suggest that harmine extends the circadian period by enhancing RORĪ± function and that harmine is a new candidate that contributes to the control of period length in mammalian cells...
  4. ncbi HSG cells, a model in the submandibular clock
    Yoshiaki Onishi
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    Biosci Rep 31:57-62. 2011
    ....
  5. ncbi Rhythmic SAF-A binding underlies circadian transcription of the Bmal1 gene
    Yoshiaki Onishi
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology AIST, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Mol Cell Biol 28:3477-88. 2008
    ..These results suggest that the unique chromatin structure containing SAF-A is required for the circadian transcriptional regulation of the Bmal1 gene in cells...
  6. ncbi Enhancer activity of HS2 of the human beta-LCR is modulated by distance from the key nucleosome
    Y Onishi
    Institute of Molecular and Cell Biology, AIST Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Nucleic Acids Res 29:3448-57. 2001
    ..At this state, enhancer activity was approximately 50% of that in the original construct, presumably due to reduced binding of transcription factors...
  7. ncbi Preparation and characterization of an anti-DNA monoclonal antibody showing size selectivity toward DNA fragments
    Yoshiaki Onishi
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Ibaraki, Japan
    Hybrid Hybridomics 23:311-7. 2004
    ..The antibody reacted only with DNA fragments longer than 0.8 kbp, and its apparent dissociation constant for a 1.0-kbp DNA fragment was 34 nM. This antibody will be a helpful tool for the detection of DNA structures...
  8. ncbi Interaction of NF-E2 in the human beta-globin locus control region before chromatin remodeling
    Yoshiaki Onishi
    Research Center for Glycoscience, National Institute of Advanced Industrial Science and Technology, AIST Tsukuba Central 6, 1 1 1 Higashi, Ibaraki 305 8566, Japan
    J Biol Chem 278:8163-71. 2003
    ..These lines of evidence indicate that NF-E2 interacts with the cognate motif on the nucleosome before chromatin is remodeled...
  9. ncbi Biochemical screening of stable dinucleosomes using DNA fragments from a dinucleosome DNA library
    Megumi Kato
    Research Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan
    J Mol Biol 350:215-27. 2005
    ..These results suggest that information for forming stable dinucleosome is embedded in the genomic DNA and that a further characterization of the key nucleosome is useful for understanding the building up of the chromatin structure...
  10. ncbi Evolutionary conservation and functional synergism of curved DNA at the mouse epsilon- and other globin-gene promoters
    Chanane Wanapirak
    Research Center for Glycoscience, National Institute of Advanced Industrial Science and Technology, AIST Tsukuba Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan
    J Mol Evol 56:649-57. 2003
    ..Based on these results, DNA curvature is one of the major features of these promoter regions which might influence transcription through nucleosome positioning...
  11. ncbi The negative transcription factor E4BP4 is associated with circadian clock protein PERIOD2
    Tomoya Ohno
    Clock Cell Biology, Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Central 6 5, 1 1 1 Higashi, Tsukuba, Japan
    Biochem Biophys Res Commun 354:1010-5. 2007
    ..We also found that E4BP4 interacts with CRYPTOCHROME2 (CRY2), a key negative regulator in the mammalian circadian clock. These results suggest that E4BP4 is a component of the negative regulator complex of mammalian circadian clocks...
  12. ncbi Conserved amino acid residues in C-terminus of PERIOD 2 are involved in interaction with CRYPTOCHROME 1
    Tatsunosuke Tomita
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Tsukuba Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Biochim Biophys Acta 1803:492-8. 2010
    ..Thus, the conserved amino acid residues of 1179-1198 in PER2 are apparently responsible for binding to CRY1...
  13. ncbi A novel E4BP4 element drives circadian expression of mPeriod2
    Tomoya Ohno
    Clock Cell Biology, Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba 305 8566, Japan
    Nucleic Acids Res 35:648-55. 2007
    ..These findings indicated that E4BP4 is required for the negative regulation of mammalian circadian clocks...
  14. ncbi Ligand-dependent transcriptional enhancement by DNA curvature between two half motifs of the estrogen response element in the human estrogen receptor alpha gene
    Xiao-man Li
    Research Center for Glycoscience, National Institute of Advanced Industrial Science and Technology, AIST Central 6, 1-1-1 Higashi, Tsukuba, 305-8566, Ibaraki, Japan
    Gene 294:279-90. 2002
    ..These findings suggest that some DNA curvature acts as a transcriptional modulator by modifying the state of ligand effects...
  15. ncbi Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter
    Yasuhiro Hara
    Clock Cell Biology, Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Japan
    Nucleic Acids Res 37:1115-26. 2009
    ..These findings suggest that Mybbp1a and mCRY1 can form complexes on the Per2 promoter that function as negative regulators of Per2 expression...
  16. ncbi Dinucleosome DNA of human K562 cells: experimental and computational characterizations
    Megumi Kato
    Research Institute of Glycoscience, National Institute of Advanced Industrial Science and Technology, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan
    J Mol Biol 332:111-25. 2003
    ..Also an important finding is that the distributions of AA/TT and other RR/YY dinucleotides, apparently, reflect both DNA curvature and DNA bendability, cooperatively contributing to the nucleosome formation...
  17. ncbi Identification of negative transcriptional factor E4BP4-binding site in the mouse circadian-regulated gene Mdr2
    Maki Kotaka
    Clock Cell Biology Research Group, Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba 305 8566, Japan
    Neurosci Res 60:307-13. 2008
    ..Chromatin immunoprecipitation and gel shift assays showed that E4BP4 binds to the D2 site, but not to the D1 site. These data suggested that E4BP4 is a negative transcription factor for circadian Mdr2 mRNA expression...
  18. ncbi Alternative splicing of the human Kank gene produces two types of Kank protein
    Yong Wang
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305 8566, Japan
    Biochem Biophys Res Commun 330:1247-53. 2005
    ..Promoter activity and the expression of the Kank variants in normal and cancer tissues were examined...