Masato Naya

Summary

Affiliation: National Institute of Advanced Industrial Science and Technology
Country: Japan

Publications

  1. doi request reprint In vivo genotoxicity study of titanium dioxide nanoparticles using comet assay following intratracheal instillation in rats
    Masato Naya
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, 16 1 Onogawa, Tsukuba, Ibaraki 305 8569, Japan
    Regul Toxicol Pharmacol 62:1-6. 2012
  2. doi request reprint In vivo genotoxicity study of single-wall carbon nanotubes using comet assay following intratracheal instillation in rats
    Masato Naya
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, Ibaraki, Japan
    Regul Toxicol Pharmacol 64:124-9. 2012
  3. ncbi request reprint Risk assessment of formaldehyde for the general population in Japan
    Masato Naya
    Research Center for Chemical Risk Management, National Institute of Advanced Industrial Science and Technology, Onogawa 16 1, Tsukuba, Ibaraki 305 8569, Japan
    Regul Toxicol Pharmacol 43:232-48. 2005
  4. doi request reprint Evaluation of the genotoxic potential of single-wall carbon nanotubes by using a battery of in vitro and in vivo genotoxicity assays
    Masato Naya
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, Ibaraki, Japan
    Regul Toxicol Pharmacol 61:192-8. 2011
  5. ncbi request reprint Genotoxicity evaluation for single-walled carbon nanotubes in a battery of in vitro and in vivo assays
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, Ibaraki, 305 8569, Japan
    J Appl Toxicol 33:933-9. 2013
  6. doi request reprint Genotoxicity evaluation of fullerene C60 nanoparticles in a comet assay using lung cells of intratracheally instilled rats
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, 16 1 Onogawa, Tsukuba, Ibaraki 305 8569, Japan
    Regul Toxicol Pharmacol 62:419-24. 2012
  7. ncbi request reprint In vivo comet assay of multi-walled carbon nanotubes using lung cells of rats intratracheally instilled
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, 16 1 Onogawa, Tsukuba, Ibaraki, 305 8569, Japan
    J Appl Toxicol 33:1053-60. 2013
  8. doi request reprint Dermal and ocular irritation and skin sensitization studies of fullerene C60 nanoparticles
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology, Onogawa, Tsukuba, Ibaraki, Japan
    Cutan Ocul Toxicol 32:128-34. 2013
  9. doi request reprint Evaluation of genotoxicity of multi-walled carbon nanotubes in a battery of in vitro and in vivo assays
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, Ibaraki 305 8569, Japan
    Regul Toxicol Pharmacol 63:188-95. 2012
  10. pmc Pulmonary and systemic responses of highly pure and well-dispersed single-wall carbon nanotubes after intratracheal instillation in rats
    Norihiro Kobayashi
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    Inhal Toxicol 23:814-28. 2011

Detail Information

Publications18

  1. doi request reprint In vivo genotoxicity study of titanium dioxide nanoparticles using comet assay following intratracheal instillation in rats
    Masato Naya
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, 16 1 Onogawa, Tsukuba, Ibaraki 305 8569, Japan
    Regul Toxicol Pharmacol 62:1-6. 2012
    ..In the EMS group, there was a significant increase in % tail DNA compared with the negative control group. TiO₂ nanoparticles in the anatase crystal phase are not genotoxic following intratracheal instillation in rats...
  2. doi request reprint In vivo genotoxicity study of single-wall carbon nanotubes using comet assay following intratracheal instillation in rats
    Masato Naya
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, Ibaraki, Japan
    Regul Toxicol Pharmacol 64:124-9. 2012
    ..Under the conditions of the test, SWCNTs were not genotoxic in the comet assay following intratracheal instillation in rats...
  3. ncbi request reprint Risk assessment of formaldehyde for the general population in Japan
    Masato Naya
    Research Center for Chemical Risk Management, National Institute of Advanced Industrial Science and Technology, Onogawa 16 1, Tsukuba, Ibaraki 305 8569, Japan
    Regul Toxicol Pharmacol 43:232-48. 2005
    ..The reference concentration of formaldehyde in atmosphere for the Japanese general population is recommended to be 0.01 ppm...
  4. doi request reprint Evaluation of the genotoxic potential of single-wall carbon nanotubes by using a battery of in vitro and in vivo genotoxicity assays
    Masato Naya
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, Ibaraki, Japan
    Regul Toxicol Pharmacol 61:192-8. 2011
    ....
  5. ncbi request reprint Genotoxicity evaluation for single-walled carbon nanotubes in a battery of in vitro and in vivo assays
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, Ibaraki, 305 8569, Japan
    J Appl Toxicol 33:933-9. 2013
    ..SWCNTs appear not to pose a genotoxic risk...
  6. doi request reprint Genotoxicity evaluation of fullerene C60 nanoparticles in a comet assay using lung cells of intratracheally instilled rats
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, 16 1 Onogawa, Tsukuba, Ibaraki 305 8569, Japan
    Regul Toxicol Pharmacol 62:419-24. 2012
    ..These findings indicate that C(60) nanoparticles had no potential for DNA damage in comet assays using the lungs cells of rats given C(60) even at doses causing inflammation...
  7. ncbi request reprint In vivo comet assay of multi-walled carbon nanotubes using lung cells of rats intratracheally instilled
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, 16 1 Onogawa, Tsukuba, Ibaraki, 305 8569, Japan
    J Appl Toxicol 33:1053-60. 2013
    ..These findings indicate that MWCNTs do not have the potential to cause DNA damage in comet assays using the lung cells of rats given MWCNTs at doses causing inflammatory responses...
  8. doi request reprint Dermal and ocular irritation and skin sensitization studies of fullerene C60 nanoparticles
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology, Onogawa, Tsukuba, Ibaraki, Japan
    Cutan Ocul Toxicol 32:128-34. 2013
    ..However, information on the dermal and eye irritation and sensitization of fullerene C(60) nanoparticles is still lacking...
  9. doi request reprint Evaluation of genotoxicity of multi-walled carbon nanotubes in a battery of in vitro and in vivo assays
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, Ibaraki 305 8569, Japan
    Regul Toxicol Pharmacol 63:188-95. 2012
    ..In ICR mice, the two products did not affect the proportion of immature erythrocytes, the total proportion of erythrocytes, or the number of micronuclei in immature erythrocytes...
  10. pmc Pulmonary and systemic responses of highly pure and well-dispersed single-wall carbon nanotubes after intratracheal instillation in rats
    Norihiro Kobayashi
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan
    Inhal Toxicol 23:814-28. 2011
    ..For all groups, histopathological changes due to the instillation exposure of SWCNTs were observed only in the lungs and lung-associated lymph nodes and not in the other tissues examined (i.e. the liver, kidney, spleen, and cerebrum)...
  11. doi request reprint Biological response and morphological assessment of individually dispersed multi-wall carbon nanotubes in the lung after intratracheal instillation in rats
    Norihiro Kobayashi
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology, 16 1 Onagawa, Tsukuba, Ibaraki 305 8569, Japan
    Toxicology 276:143-53. 2010
    ..There was no evidence of chronic inflammation, such as angiogenesis or fibrosis, induced by MWCNT instillation. These results suggest that MWCNTs were being processed and cleared by alveolar macrophages...
  12. doi request reprint Comparative pulmonary toxicity study of nano-TiO(2) particles of different sizes and agglomerations in rats: different short- and long-term post-instillation results
    Norihiro Kobayashi
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305 8569, Japan
    Toxicology 264:110-8. 2009
    ..Consequently, our findings indicate that both short- and long-term effects should be evaluated when assessing the toxicity of nanoparticles based on the results of intratracheal instillation studies...
  13. doi request reprint Reproductive and developmental toxicity studies of manufactured nanomaterials
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Science and Technology AIST, 16 1 Onogawa, Tsukuba, Ibaraki 305 8569, Japan
    Reprod Toxicol 30:343-52. 2010
    ....
  14. doi request reprint Reproductive and developmental toxicity of hydrofluorocarbons used as refrigerants
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Science and Technology AIST, Tsukuba, Ibaraki 305 8569, Japan
    Reprod Toxicol 29:125-31. 2010
    ..It is required to reduce emissions of organic vapors containing HFCs to reduce the risk of exposure...
  15. doi request reprint Evaluation of dermal and eye irritation and skin sensitization due to carbon nanotubes
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Science and Technology AIST, 16 1 Onogawa, Tsukuba, Ibaraki 305 8569, Japan
    Regul Toxicol Pharmacol 61:276-81. 2011
    ..Our knowledge of the toxicological effects of CNTs is still limited. Further information is needed to clarify the potential for irritation and sensitization given the complex nature of CNTs...
  16. ncbi request reprint Developmental toxicity of diesel exhaust: a review of studies in experimental animals
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology AIST, 16 1 Onogawa, Tsukuba, Ibaraki 305 8569, Japan Electronic address
    Reprod Toxicol 42:1-17. 2013
    ....
  17. doi request reprint Historical control data on prenatal developmental toxicity studies in rabbits
    Makoto Ema
    Study Group for Historical Control Data on Prenatal Developmental Toxicity Studies in Rabbits, Research Institute of Sciencefor Safety and Sustainability, National Institute of Advanced IndustrialScience and Technology AIST, 16 1 Onogawa, Tsukuba, Ibaraki, Japan
    Congenit Anom (Kyoto) 52:155-61. 2012
    ....
  18. doi request reprint Reproductive and developmental toxicity of degradation products of refrigerants in experimental animals
    Makoto Ema
    Research Institute of Science for Safety and Sustainability, National Institute of Advanced Science and Technology AIST, 16 1 Onogawa, Tsukuba, Ibaraki 305 8569, Japan
    Reprod Toxicol 29:1-9. 2010
    ..Rat multiple-generation studies revealed that NaF caused retarded ossification and degenerative changes in the lung and kidney in offspring. There is a lack of information about the toxicity of TFA and FA...