Hiroshi Nawashiro

Summary

Affiliation: National Defense Medical College
Country: Japan

Publications

  1. doi request reprint Focal increase in cerebral blood flow after treatment with near-infrared light to the forehead in a patient in a persistent vegetative state
    Hiroshi Nawashiro
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    Photomed Laser Surg 30:231-3. 2012
  2. ncbi request reprint L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors
    Hiroshi Nawashiro
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    Int J Cancer 119:484-92. 2006
  3. ncbi request reprint High expression of L-type amino acid transporter 1 in infiltrating glioma cells
    Hiroshi Nawashiro
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    Brain Tumor Pathol 22:89-91. 2005
  4. pmc Improved brain MRI indices in the acute brain stem infarct sites treated with hydroxyl radical scavengers, Edaravone and hydrogen, as compared to Edaravone alone. A non-controlled study
    Hirohisa Ono
    Department of Neurosurgery, Nishijima Hospital, Oooka, Numazu City, Sizuoka, 410 0022, Japan
    Med Gas Res 1:12. 2011
  5. doi request reprint Prognostic factors in patients with primary brainstem hemorrhage
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Clin Neurol Neurosurg 115:732-5. 2013
  6. doi request reprint Ventriculomegaly after decompressive craniectomy with hematoma evacuation for large hemispheric hypertensive intracerebral hemorrhage
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Clin Neurol Neurosurg 115:317-22. 2013
  7. doi request reprint The effect of hydrogen gas on a mouse bilateral common carotid artery occlusion
    Kimihiro Nagatani
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Acta Neurochir Suppl 118:61-3. 2013
  8. ncbi request reprint Role of the activated extracellular signal-regulated kinase pathway on histological and behavioral outcome after traumatic brain injury in rats
    Naoki Otani
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    J Clin Neurosci 14:42-8. 2007
  9. ncbi request reprint Nuclear accumulation of basic fibroblast growth factor in human astrocytic tumors
    Shinji Fukui
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
    Cancer 97:3061-7. 2003
  10. doi request reprint Adiponectin and traumatic brain injury
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Acta Neurochir Suppl 118:111-4. 2013

Collaborators

Detail Information

Publications78

  1. doi request reprint Focal increase in cerebral blood flow after treatment with near-infrared light to the forehead in a patient in a persistent vegetative state
    Hiroshi Nawashiro
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    Photomed Laser Surg 30:231-3. 2012
    ..This study aimed to quantify the cerebral blood flow (CBF) after bilateral, transcranial near-infrared light-emitting diode (LED) irradiation to the forehead in a patient in a persistent vegetative state following severe head injury...
  2. ncbi request reprint L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors
    Hiroshi Nawashiro
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    Int J Cancer 119:484-92. 2006
    ..Kaplan-Meier survival data of rats treated with BCH were significant. These findings suggest that LAT1 could be one of the molecular targets in glioma therapy...
  3. ncbi request reprint High expression of L-type amino acid transporter 1 in infiltrating glioma cells
    Hiroshi Nawashiro
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    Brain Tumor Pathol 22:89-91. 2005
    ..The expression of LAT1 was always higher in infiltrating glioma cells than in cells located in the center of the tumor. These findings suggest that LAT1 is one of the molecular targets for glioma therapy...
  4. pmc Improved brain MRI indices in the acute brain stem infarct sites treated with hydroxyl radical scavengers, Edaravone and hydrogen, as compared to Edaravone alone. A non-controlled study
    Hirohisa Ono
    Department of Neurosurgery, Nishijima Hospital, Oooka, Numazu City, Sizuoka, 410 0022, Japan
    Med Gas Res 1:12. 2011
    ..abstract:..
  5. doi request reprint Prognostic factors in patients with primary brainstem hemorrhage
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Clin Neurol Neurosurg 115:732-5. 2013
    ..The aim of this study was to analyze the impact of clinical or radiologic parameters on the outcome of patients with PBH...
  6. doi request reprint Ventriculomegaly after decompressive craniectomy with hematoma evacuation for large hemispheric hypertensive intracerebral hemorrhage
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Clin Neurol Neurosurg 115:317-22. 2013
    ....
  7. doi request reprint The effect of hydrogen gas on a mouse bilateral common carotid artery occlusion
    Kimihiro Nagatani
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Acta Neurochir Suppl 118:61-3. 2013
    ..In conclusion, hydrogen gas might be effective in a mouse BCCAO model...
  8. ncbi request reprint Role of the activated extracellular signal-regulated kinase pathway on histological and behavioral outcome after traumatic brain injury in rats
    Naoki Otani
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    J Clin Neurosci 14:42-8. 2007
    ..In addition, administration of U0126 ameliorated motor function recovery on days 3, 4 and 5 after injury. Therefore, inhibition of ERK phosphorylation could be a potentially effective therapeutic target after TBI...
  9. ncbi request reprint Nuclear accumulation of basic fibroblast growth factor in human astrocytic tumors
    Shinji Fukui
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
    Cancer 97:3061-7. 2003
    ..The current study sought to determine whether nuclear bFGF accumulation was a predictor of survival in patients with astrocytic tumors...
  10. doi request reprint Adiponectin and traumatic brain injury
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Acta Neurochir Suppl 118:111-4. 2013
    ..Our findings suggest that adiponectin might participate in the pathophysiological process occurring after traumatic brain injury...
  11. doi request reprint L-Leucine induces growth arrest and persistent ERK activation in glioma cells
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    Amino Acids 43:717-24. 2012
    ..These data suggest that high concentration L-leucine combined with inhibition of MEK is a potential strategy for glioma cell growth arrest...
  12. ncbi request reprint Subcellular localization of basic fibroblast growth factor and fibroblast growth factor receptor 1 in pituitary adenomas
    Shinji Fukui
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    Brain Tumor Pathol 19:23-9. 2002
    ..These findings suggest that the nuclear accumulation of bFGF plays an important role in the progression of pituitary adenomas without its receptors...
  13. ncbi request reprint Revascularization for anterior cerebral artery dissecting aneurysms--three case reports
    Yoichi Uozumi
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    Neurol Med Chir (Tokyo) 50:49-53. 2010
    ..We recommend early treatment with revascularization for patients with ACA dissection that has hemorrhaged and for patients presenting with signs of clinical deterioration with ischemic event...
  14. doi request reprint Evaluation of the stage of hemorrhage using optical diffuse reflectance spectroscopy: an in vivo study
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Acta Neurochir Suppl 118:45-8. 2013
    ..In conclusion, the results of the present study suggest that ODRS allows clinicians to more easily evaluate the stage of hemorrhage at the patient's bedside...
  15. doi request reprint Is decompressive craniectomy a risk factor for ventriculomegaly?
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
    Acta Neurochir Suppl 118:281-3. 2013
    ..Nevertheless, ventriculomegaly can occur after TBI even without DC. The aim of the present study was to investigate the influence of DC on ventriculomegaly...
  16. doi request reprint Hydrocephalus following decompressive craniectomy for ischemic stroke
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Acta Neurochir Suppl 118:289-91. 2013
    ..We consider that the explanation for the discrepancies between our study and the previous studies might lie in the definition of hydrocephalus and the indications for shunting...
  17. ncbi request reprint Cerebral infarction along the distribution of perforating arteries during aneurysm surgery in a patient with pheochromocytoma--case report
    Nobusuke Tsuzuki
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    Neurol Med Chir (Tokyo) 51:72-5. 2011
    ..Hypervolemic fluid infusion and maintenance of normotensive blood pressure during surgery may avoid such ischemic events...
  18. doi request reprint Light scattering change precedes loss of cerebral adenosine triphosphate in a rat global ischemic brain model
    Satoko Kawauchi
    Department of Medical Engineering, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    Neurosci Lett 459:152-6. 2009
    ..DC potential measurement showed that the triphasic scattering change was associated with anoxic depolarization. These findings suggest that light scattering signal can be used as an indicator of loss of tissue viability in brains...
  19. ncbi request reprint Up-regulation of L type amino acid transporter 1 after spinal cord injury in rats
    Terushige Toyooka
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    Acta Neurochir Suppl 102:385-8. 2008
    ..L-type amino acid transporter 1 (LAT1) is proposed to be a major nutrient transporter at the blood brain barrier. LAT1 requires the heavy chain of 4F2 cell surface antigen (4F2hc) for functional expression...
  20. doi request reprint A better mild traumatic brain injury model in the rat
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Acta Neurochir Suppl 118:99-101. 2013
    ..The present study shows that this model is capable of reproducing the histological changes associated with mild TBI...
  21. doi request reprint Increased xCT expression correlates with tumor invasion and outcome in patients with glioblastomas
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    Neurosurgery 72:33-41; discussion 41. 2013
    ..Furthermore, increased glutathione synthesis by system xc may protect tumor cells against oxidative stress induced by radiotherapy and chemotherapy...
  22. doi request reprint Hydrocephalus after decompressive craniectomy for hemispheric cerebral infarction
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    J Clin Neurosci 20:377-82. 2013
    ..031, p=0.049, respectively). DC with a superior limit <25 mm from the midline should be avoided to prevent the development of hydrocephalus...
  23. doi request reprint Decompressive craniectomy with hematoma evacuation for large hemispheric hypertensive intracerebral hemorrhage
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    Acta Neurochir Suppl 118:277-9. 2013
    ..029). Our results suggest that DC with hematoma evacuation might be a useful surgical procedure for selected patients with large hemispheric hypertensive ICH...
  24. doi request reprint Traumatic basal ganglia hematomas: an analysis of 20 cases
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    Acta Neurochir Suppl 118:139-42. 2013
    ....
  25. doi request reprint Traumatic peritentorial subdural hematomas: a study of 32 cases
    Satoru Takeuchi
    National Defense Medical College, Department of Neurosurgery, Saitama, Japan
    Turk Neurosurg 22:305-8. 2012
    ..This study aimed to investigate the clinicoradiological features in patients with traumatic peritentorial subdural hematomas (SDHs)...
  26. ncbi request reprint Enhanced hippocampal neurodegeneration after traumatic or kainate excitotoxicity in GFAP-null mice
    Naoki Otani
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    J Clin Neurosci 13:934-8. 2006
    ..These results indicate that GFAP plays a crucial role in pyramidal neuronal survival after injury or KA-induced neurotoxicity...
  27. ncbi request reprint Gender disparities in serum electrolytes levels after subarachnoid hemorrhage
    Shinji Fukui
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    J Clin Neurosci 11:606-9. 2004
    ..Serum potassium levels were inversely related to serum levels of catecholamines, especially adrenaline, during the acute and subacute phases, particularly on the first day...
  28. ncbi request reprint Normal pressure hydrocephalus manifesting as transient prosopagnosia, topographical disorientation, and visual objective agnosia
    Naoki Otani
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    J Clin Neurosci 11:313-7. 2004
    ..ECD-SPECT showed a reduction of the cerebral blood flow (CBF) in the periventricular deep white matter. Three months after CSF shunting, the radiological findings normalized with dramatic improvement of the extremely rare symptoms...
  29. doi request reprint Traumatic hematoma of the posterior fossa
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Acta Neurochir Suppl 118:135-8. 2013
    ..The present study suggests that repeat CT imaging and careful management are necessary until the lesion is stabilized, and patients showing lesions with mass effects should therefore be immediately treated with surgery...
  30. doi request reprint Surgical results after primary decompressive craniectomy in poor-grade aneurysmal subarachnoid hemorrhage
    Naoki Otani
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Acta Neurochir Suppl 118:269-72. 2013
    ..We suggest that the DC provided the efficacy in reducing mortality in poor-grade SAH patients...
  31. doi request reprint Vestibular schwannoma with repeated intratumoral hemorrhage
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    J Clin Neurosci 19:1305-7. 2012
    ..A histopathological examination of the resected specimen showed typical features of schwannoma. We review the pertinent literature and discuss the features of repeated hemorrhage from a vestibular schwannoma...
  32. ncbi request reprint Focal brain edema and natriuretic peptides in patients with subarachnoid hemorrhage
    Shinji Fukui
    Department of Neurosurgery, National Defense Medical College, Namiki, Tokorozawa, Saitama, Japan
    J Clin Neurosci 11:507-11. 2004
    ..These findings suggest that focal brain aedema may have some role in the pathogenesis of an excessive secretion of ANP and BNP during the subacute phase of SAH...
  33. ncbi request reprint The association of the expression of vascular endothelial growth factor with the cystic component and haemorrhage in pituitary adenoma
    Shinji Fukui
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Saitama 359 8513, Tokorozawa, Japan
    J Clin Neurosci 10:320-4. 2003
    ..These findings suggest that VEGF plays any potential role in the pathogenesis of cystic formation in pituitary adenomas...
  34. ncbi request reprint Nuclear accumulation of basic fibroblast growth factor as a predictor for the recurrence of pituitary adenomas
    Shinji Fukui
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    J Neurooncol 57:221-9. 2002
    ..High bFGF NI (>30%) had a relative risk of 8.9, with a 95% confidence interval of 1.0-74.9 (p < 0.05). We suggest that the bFGF NI may be a potentially useful predictor for the recurrence of pituitary adenomas...
  35. ncbi request reprint The role of CD98 in astrocytic neoplasms
    Hiroshi Nawashiro
    Department of Neurosurgery, National Defense Medical College, Tokorazawa, Saitama, Japan
    Hum Cell 15:25-31. 2002
    ..Several studies implicated the important role of LAT1 and 4F2hc in malignant transformation and carcinogenesis. The LAT1-CD98 pathway may represent a unique therapeutic target for cancer intervention...
  36. doi request reprint Targeted increase in cerebral blood flow by transcranial near-infrared laser irradiation
    Yoichi Uozumi
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    Lasers Surg Med 42:566-76. 2010
    ..The precise mechanisms by which blood flow is controlled by NIR laser irradiation on the central nervous system (CNS) have not been elucidated. In this study, we examined the effect of 808 nm laser diode irradiation on CBF in mice...
  37. pmc Multivariate analysis of risk factors for QT prolongation following subarachnoid hemorrhage
    Shinji Fukui
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
    Crit Care 7:R7-R12. 2003
    ..The aim of the present study was to examine independent risk factors for QTc prolongation in patients with SAH by means of multivariate analysis...
  38. doi request reprint Cerebrospinal fluid congestion in the perioptic space
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Acta Neurochir Suppl 118:215-8. 2013
    ..Therefore, we suggest that, in patients with an expanded ON-SAS associated with mass lesions, the state of the ON-SAS should be evaluated by pre- and postoperative MRI, in addition to the degree of tumor resection...
  39. doi request reprint A suitable formula for estimating the volume gained by decompressive craniectomy in malignant hemispheric infarction
    Kimihiro Nagatani
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Acta Neurochir Suppl 118:285-8. 2013
    ..8095 (p < 0.05), 1/3ABC = 0.8095 (p < 0.05), π/6ABC = 0.7381 (p < 0.05), and 2/3Sh = 0.4524 (p > 0.05). In conclusion, the 1/2ABC formula is the most useful and the closest estimation of DV in patients with MHI after DC...
  40. doi request reprint Effect of hydrogen gas on the survival rate of mice following global cerebral ischemia
    Kimihiro Nagatani
    Department of Neurosurgery, Research Institute, National Defense Medical College, Saitama, Japan
    Shock 37:645-52. 2012
    ..Thus, we believe that H2 may be an effective treatment for global cerebral I/R...
  41. doi request reprint Down-regulation of glial fibrillary acidic protein and vimentin by RNA interference improves acute urinary dysfunction associated with spinal cord injury in rats
    Terushige Toyooka
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
    J Neurotrauma 28:607-18. 2011
    ..In conclusion, the down-regulation of IF proteins by RNAi suppresses the overproliferation of reactive astrocytes and thereby might be an effective treatment for spinal cord injury...
  42. ncbi request reprint The fate of Nissl-stained dark neurons following traumatic brain injury in rats: difference between neocortex and hippocampus regarding survival rate
    Hidetoshi Ooigawa
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    Acta Neuropathol 112:471-81. 2006
    ..These data suggest that not all N-DNs inevitably die especially in the neocortex after TBI. The fate of N-DNs is thus considered to differ depending on brain subfields...
  43. doi request reprint Temporal and spatial profile of phosphorylated connexin43 after traumatic brain injury in rats
    Atsushi Ohsumi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    J Neurotrauma 27:1255-63. 2010
    ..These findings suggest that astrocytic gap junctions participate in pathophysiological processes in the hippocampus after TBI...
  44. ncbi request reprint Non-bifurcating cervical carotid artery
    Hidetoshi Ooigawa
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    J Clin Neurosci 13:944-7. 2006
    ..The non-bifurcating carotid artery continued into the cranium as a normal internal carotid artery. This anomaly can be attributed to a maldevelopment of the vascular network during embryogenesis...
  45. doi request reprint Decompressive craniectomy after intravenous tissue plasminogen activator administration for stroke
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Clin Neurol Neurosurg 114:1312-5. 2012
    ..However, the effects of decompressive craniectomy (DC) after IV tPA administration for ischemic stroke are still largely unknown. The aim of this study was to investigate the safety and outcomes of DC after IV tPA administration...
  46. ncbi request reprint Temporal and spatial profile of phosphorylated mitogen-activated protein kinase pathways after lateral fluid percussion injury in the cortex of the rat brain
    Naoki Otani
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
    J Neurotrauma 19:1587-96. 2002
    ..The current results suggest that the ERK and JNK pathways, but not the p38 MAPK pathways are involved in signal transduction in the cortex following TBI...
  47. ncbi request reprint [Postoperative subdural empyema due to Propionibacterium acnes]
    Youichi Uozumi
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa City, Saitama 359 8513, Japan
    No Shinkei Geka 30:731-3. 2002
    ..However, high dose penicillin in combination with surgical drainage and removal of foreign bodies is recommended as the treatment of choice...
  48. ncbi request reprint Neuroendoscopic identification of a basilar artery tip aneurysm in the third ventricle. Case illustration
    Shoichiro Ishihara
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    J Neurosurg 96:1138. 2002
  49. doi request reprint Effect of decompressive craniectomy on aquaporin-4 expression after lateral fluid percussion injury in rats
    Satoshi Tomura
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    J Neurotrauma 28:237-43. 2011
    ..05). The present results suggest that decompressive craniectomy may affect AQP4 expression and reduce brain edema formation after TBI...
  50. doi request reprint Decrease in plasma adiponectin level and increase in adiponectin immunoreactivity in cortex and hippocampus after traumatic brain injury in rats
    Satoru Takeuchi
    National Defense Medical College, Department of Neurosurgery, Saitama, Japan
    Turk Neurosurg 23:349-54. 2013
    ..The aim of the present study was to examine the changes in the plasma adiponectin levels and the immunoreactivity of adiponectin in the brain after TBI. MATERIAL and..
  51. doi request reprint Postoperative computed tomography after surgery for head trauma
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    J Trauma Acute Care Surg 73:1254-60. 2012
    ..However, little is known about the factors associated with such new postoperative lesions. Here, we investigated the predictive factors of new findings (NFs) on computed tomography early after surgery...
  52. ncbi request reprint Usefulness of thallium-201 chloride single photon emission computed tomography for the preoperative diagnosis of fourth ventricle meningioma--case report
    Hidetoshi Ooigawa
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    Neurol Med Chir (Tokyo) 44:660-4. 2004
    ..Total removal of the tumor was successfully performed. 201TlCl SPECT is useful for the preoperative diagnosis of fourth ventricle meningioma combined with CT, MR imaging, and angiography...
  53. ncbi request reprint Central neurogenic hyperventilation in a conscious man with CSF dissemination from a pineal glioblastoma
    Terushige Toyooka
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
    J Clin Neurosci 12:834-7. 2005
    ..The authors suggest that multiple lesions from an infiltrative tumor in the brainstem may give rise to CNH and further our understanding of the pathogenesis of CNH...
  54. ncbi request reprint Hydrogen may inhibit collagen-induced platelet aggregation: an ex vivo and in vivo study
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Japan
    Intern Med 51:1309-13. 2012
    ..Furthermore, there is increasing evidence that antioxidants can modulate platelet activation. The aim of the present study was to investigate the relationship between hydrogen and collagen-induced platelet aggregation...
  55. ncbi request reprint Effectiveness of narrow-band ultraviolet-B phototherapy for prevention of intimal hyperplasia in a rat carotid balloon injury model
    Shinya Kohyama
    Department of Radiology, National Defense Medical College, Saitama, Japan 359 8513
    Lasers Surg Med 39:659-66. 2007
    ..We assessed the effects of NBUVB irradiation for prevention of intimal hyperplasia...
  56. pmc A ruptured internal carotid artery aneurysm located at the origin of the duplicated middle cerebral artery associated with accessory middle cerebral artery and middle cerebral artery aplasia
    Naoki Otani
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Surg Neurol Int 1:51. 2010
    ..Intracranial vascular anomalies involving the middle cerebral artery (MCA) are relatively rare, as such knowledge will be helpful for planning the optimal surgical procedures...
  57. doi request reprint An analysis of T2 mapping on brain tumors
    Kanji Nakai
    Department of Neurosurgery, Fukuoka University Chikushi Hospital, Fukuoka, Japan
    Acta Neurochir Suppl 118:195-9. 2013
    ..In this study, we assessed the diagnostic utility of T2 mapping techniques in distinguishing GBM from METS...
  58. doi request reprint Anterior cerebral artery dissecting aneurysm associated with untreated craniopharyngioma
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Br J Neurosurg 27:102-4. 2013
    ..We present an extremely rare case of anterior cerebral artery dissecting aneurysm associated with untreated craniopharyngioma, and discuss the relationship between these two lesions...
  59. doi request reprint Diffuse light reflectance signals as potential indicators of loss of viability in brain tissue due to hypoxia: charge-coupled-device-based imaging and fiber-based measurement
    Satoko Kawauchi
    National Defense Medical College Research Institute, Division of Biomedical Information Sciences, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    J Biomed Opt 18:15003. 2013
    ..We found that TRC measured by the fibers preceded the reflectance-signal change captured by the imaging. This time difference is attributable to the different observation depths in the brain with these two methods...
  60. pmc Effects of a head-down tilt on cerebral blood flow in mice during bilateral common carotid artery occlusion
    Kimihiro Nagatani
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Asian J Neurosurg 7:171-3. 2012
    ..Data on the optimal head position for patients with acute ischemic stroke are unavailable. We evaluated the effects of mild head-down tilt (HDT) on cerebral blood flow (CBF) in mice during bilateral common carotid artery occlusion (BCCAO)...
  61. ncbi request reprint Differential activation of mitogen-activated protein kinase pathways after traumatic brain injury in the rat hippocampus
    Naoki Otani
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
    J Cereb Blood Flow Metab 22:327-34. 2002
    ..These findings suggest that ERK and JNK but not p38 cascades may be closely involved in signal transduction in the rat hippocampus after traumatic brain injury...
  62. doi request reprint Usefulness of an ultrasonic scalpel to harvest and skeletonize the superficial temporal artery for extracranial-intracranial bypass surgery
    Kojiro Wada
    Department of Neurosurgery, Japan Defense Forces Central Hospital, Tokyo, Japan
    Neurosurgery 65:141-7; discussion 147-8. 2009
    ..The technique is simple and safe, and reduces bleeding. We also investigated histopathological changes in donor vessels and whether it is possible to shorten the time needed for STA harvesting using the ultrasonic scalpel...
  63. pmc Anaplastic hemangiopericytoma manifesting as a rapidly enlarging extracranial mass lesion
    Naoki Otani
    Department of Neurosurgery, National Defense Medical College, Saitama, Japan
    Asian J Neurosurg 7:29-31. 2012
    ....
  64. ncbi request reprint [Chronic subdural hematoma--recurrence and prevention]
    Fumihiro Sakakibara
    Department Neurosurgery, National Defense Medical College, Saitama, Japan
    Brain Nerve 63:69-74. 2011
    ..We reviewed the risk factors for recurrence, surgical procedures used, perioperative management, timing of operation, and medical treatment...
  65. doi request reprint Light-scattering signal may indicate critical time zone to rescue brain tissue after hypoxia
    Satoko Kawauchi
    National Defense Medical College, Department of Medical Engineering, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    J Biomed Opt 16:027002. 2011
    ..The results demonstrate that light scattering signal can be an indicator of brain tissue reversibility...
  66. doi request reprint Traumatic posterior fossa subdural hematomas
    Satoru Takeuchi
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama, Japan
    J Trauma Acute Care Surg 72:480-6. 2012
    ..The aim of this study was to investigate the features of traumatic posterior fossa SDHs...
  67. doi request reprint Pilomyxoid astrocytoma of the fourth ventricle in an adult
    Tomoko Omura
    Department of Neurosurgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama, 359 8513, Japan
    Acta Neurochir (Wien) 150:1203-6; discussion 1206. 2008
    ..Pilomyxoid astrocytomas are not limited to the hypothalamic/chiasmatic region in children. Additional knowledge and recognition of this entity is necessary to improve treatment of pilomyxoid astrocytoma...
  68. ncbi request reprint Histopathologic findings in human cerebral aneurysms embolized with platinum coils: report of two cases and review of the literature
    Shoichiro Ishihara
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    AJNR Am J Neuroradiol 23:970-4. 2002
    ..We confirm that endothelial growth can be induced as early as 2 weeks after embolization of small human aneurysms with platinum coils, similar to previous observations in animal models and human cases...
  69. ncbi request reprint [Diagnostic efficacy and pitfalls of a 64-raw multislice computed tomography scan for mild head injuries in children]
    Yoshihisa Matsumoto
    Department of Neurosurgery, National Defense Medical College, Tokorozawa City, Saitama, Japan
    No Shinkei Geka 38:35-40. 2010
    ..By the 3D-reconstructive CT scan, it is easier to detect not only the intracranial lesions but also the cranial fracture. But, the diploic vein is apt to be misdiagnosed as the fracture line, especially in patients under the age of 6...
  70. ncbi request reprint Subcutaneous seeding of pancreatic carcinoma along a VP shunt catheter
    Hiroshi Nawashiro
    Department of Neurosurgery National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    Lancet Oncol 3:683. 2002
  71. ncbi request reprint High affinity D- and L-serine transporter Asc-1: cloning and dendritic localization in the rat cerebral and cerebellar cortices
    Hirotaka Matsuo
    First Department of Physiology, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    Neurosci Lett 358:123-6. 2004
    ....
  72. ncbi request reprint Simultaneous measurement of changes in light absorption due to the reduction of cytochrome c oxidase and light scattering in rat brains during loss of tissue viability
    Satoko Kawauchi
    Department of Medical Engineering, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    Appl Opt 47:4164-76. 2008
    ..These findings suggest that the simultaneous measurement of absorption signals related to the redox changes in the CcO and the scattering signal is useful for monitoring tissue viability in the brain...
  73. ncbi request reprint Combined 201Tl and 67Ga brain SPECT in patients with suspected central nervous system lymphoma or germinoma: clinical and economic value
    Shigeru Kosuda
    Department of Radiology, National Defense Medical College, Namiki Tokorozawa, Japan
    Ann Nucl Med 17:359-67. 2003
    ..Surgical resection is costly and an unfavorable prognostic factor for primary central nervous system (CNS) lymphoma and germinoma patients...
  74. ncbi request reprint [Bilateral ptosis and upper gaze palsy with pupil sparing caused by midbrain hemorrhage]
    Satoru Takeuchi
    Department of Neurosurgery, Hakodate Red Cross Hospital, 6 21 Horikawa cho, Hakodate shi, Hokkaido 040 8631, Japan
    No To Shinkei 57:899-901. 2005
    ..Furthermore, crossed innervation of the superior rectus muscle can explain that lesions located in the dorsal midbrain tegmentum cause more often impaired supraduction...
  75. ncbi request reprint [The characteristics of blast traumatic brain injury]
    Yoshihisa Matsumoto
    Department of Neurosurgery, Japan Self Defense Force Central Hospital, Japan
    No Shinkei Geka 38:695-702. 2010
    ..Treatment of bTBI patients may require clinical knowledge and skills related to intensive care, neurology, and neurosurgery. Moreover, further research is required in this field...
  76. doi request reprint Novel therapeutic use of polysaccharide nanosheets for arachnoid plasty and enhancement of venous tensile strength in rat microneurosurgery
    Naoki Otani
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan
    J Clin Neurosci 20:301-5. 2013
    ..We report that polysaccharide nanosheets can be used for arachnoid plasty without chemical bonding agents and for reinforcement of venous tensile strength in rat vessels. Nanosheets may be an effective neurosurgical tool...
  77. ncbi request reprint Infantile ependymoma with cerebrospinal dissemination at diagnosis
    Hiroshi Nawashiro
    Department of Neurosurgery and Pediatrics, National Defense Medical College, Tokorozawa, Saitama, Japan
    J Pediatr 140:276. 2002
  78. ncbi request reprint Post-ischemic transcriptional and translational responses of EC-SOD in mouse brain and serum
    Shinji Fukui
    Department of Neurosurgery, National Defense Medical College, Tokorozawa, Japan
    Free Radic Biol Med 32:289-98. 2002
    ..These findings suggest that EC-SOD accumulates on endothelial cells in response to this injury by an unknown mechanism, while cortical neurons produce EC-SOD themselves after cerebral ischemia with reperfusion...