Research Topics
| Atsushi NambuSummaryAffiliation: National Institute for Physiological Sciences Country: Japan Publications
| Collaborators
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Detail Information
Publications
A new dynamic model of the cortico-basal ganglia loopAtsushi Nambu
Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Tokyo 183 8526, Japan
Prog Brain Res 143:461-6. 2004..This sequential information processing ensures that only the selected motor program is initiated, executed and terminated at the appropriate times, whereas other competing programs are canceled...
Seven problems on the basal gangliaAtsushi Nambu
Division of System Neurophysiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, Japan
Curr Opin Neurobiol 18:595-604. 2008....- [Functions of direct, indirect and hyperdirect pathways]Atsushi Nambu
Division of System Neurophysiology, National Institute for Physiological Sciences, 38 Nishigo naka, Myodaiji, Okazaki 444 8585, Japan
Brain Nerve 61:360-72. 2009.... - A new approach to understand the pathophysiology of Parkinson's diseaseAtsushi Nambu
Division of System Neurophysiology, National Institute for Physiological Sciences, 38 Nishigonaka, Myodaiji, Okazaki 444 8585, Japan
J Neurol 252:IV1-IV4. 2005.... - Globus pallidus internal segmentAtsushi Nambu
Division of System Neurophysiology, National Institute for Physiological Sciences, 38 Nishigo naka, Myodaiji, Okazaki 444 8585, Japan
Prog Brain Res 160:135-50. 2007..The GP(i) finally conveys processed information outside the basal ganglia. Changes in GABAergic neurotransmission have been reported in movement disorders and suggested to play an important role in the pathophysiology of the symptoms... - [Physiology for the stereotactic neurosurgery: a guide to stereotactic brain operations]Atsushi Nambu
Division of System Neurophysiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444-8585, Japan
No Shinkei Geka 32:179-91. 2004 - Somatotopically arranged inputs from putamen and subthalamic nucleus to primary motor cortexShigehiro Miyachi
Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Tokyo 183 8526, Japan
Neurosci Res 56:300-8. 2006.... - Topographic distribution of output neurons in cerebellar nuclei and cortex to somatotopic map of primary motor cortexXiaofeng Lu
Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Tokyo, Japan
Eur J Neurosci 25:2374-82. 2007..These results indicate that the hindlimb, proximal forelimb and distal forelimb are arranged rostrocaudally in the DN and AIN, whereas there is dual somatotopy along the rostrocaudal and lateromedial axes in the cerebellar cortex... - Input-output organization of the rostral part of the dorsal premotor cortex, with special reference to its corticostriatal projectionYoshihisa Tachibana
Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Tokyo 183-8526, Japan
Neurosci Res 48:45-57. 2004..These data indicate that the input-output pattern of the PMdr resembles those of the presupplementary motor area and the rostral cingulate motor area, and that the PMdr may play critical roles in higher-order motor functions... - Motor cortical control of internal pallidal activity through glutamatergic and GABAergic inputs in awake monkeysYoshihisa Tachibana
Division of System Neurophysiology, National Institute for Physiological Sciences, The Graduate University for Advanced Studies, Myodaiji, Okazaki 444 8585, Japan
Eur J Neurosci 27:238-53. 2008..The inhibition is GABAergic and induced by the cortico-striato-GPi pathway. In addition, these inputs are the main factors governing the spontaneous activity of GPi neurons... - Subthalamo-pallidal interactions underlying parkinsonian neuronal oscillations in the primate basal gangliaYoshihisa Tachibana
Division of System Neurophysiology, National Institute for Physiological Sciences, Okazaki, Aichi, Japan
Eur J Neurosci 34:1470-84. 2011.... - Thalamocortical and intracortical connections of monkey cingulate motor areasNobuhiko Hatanaka
Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Japan
J Comp Neurol 462:121-38. 2003.... - Organization of corticostriatal motor inputs in monkey putamenAtsushi Nambu
Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Tokyo 183 8526, Japan
J Neurophysiol 88:1830-42. 2002..In addition, the corticostriatal inputs from the forelimb region of the MI exhibited a distal to proximal somatotopic organization along the ventrodorsal axis of the Put... - Differential activity patterns of putaminal neurons with inputs from the primary motor cortex and supplementary motor area in behaving monkeysSayuki Takara
Division of System Neurophysiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, Aichi 444 8585, Japan
J Neurophysiol 106:1203-17. 2011.... 
Cortically evoked long-lasting inhibition of pallidal neurons in a transgenic mouse model of dystoniaSatomi Chiken
Division of System Neurophysiology, National Institute for Physiological Sciences and Department of Physiological Sciences, Graduate University for Advanced Studies, Myodaiji, Okazaki 444 8585, Japan
J Neurosci 28:13967-77. 2008..Long-lasting inhibition induced by cortical inputs in the internal pallidal segment may disinhibit thalamic and cortical activity, resulting in the motor hyperactivity observed in the transgenic mice...- Organization of multisynaptic inputs from prefrontal cortex to primary motor cortex as revealed by retrograde transneuronal transport of rabies virusShigehiro Miyachi
Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Tokyo 183 8526, Japan
J Neurosci 25:2547-56. 2005..The present results suggest the importance of ventral area 46 in the cognitive control of forelimb movements... - Neural coding of "attention for action" and "response selection" in primate anterior cingulate cortexYoshikazu Isomura
Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Fuchu, Tokyo 183 8526, Japan
J Neurosci 23:8002-12. 2003.... - Input-output organization of jaw movement-related areas in monkey frontal cortexNobuhiko Hatanaka
Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Japan
J Comp Neurol 492:401-25. 2005..Our results suggest that the four jaw movement-related cortical areas may play important roles in the formation of distinctive masticatory patterns... - A neural correlate of the processing of multi-second time intervals in primate prefrontal cortexNaosugi Yumoto
Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Tokyo, Japan
PLoS ONE 6:e19168. 2011..These results suggest that area 9 may process multi-second intervals not only in perceptual recognition, but also in internal generation of time intervals... - Differential expression patterns of mGluR1 alpha in monkey nigral dopamine neuronsKatsuyuki Kaneda
Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Tokyo 183 8526, Japan
Neuroreport 14:947-50. 2003..These results suggest that mGluR1alpha expression may be involved at least partly in the vulnerability of dopaminergic neurons to parkinsonian insults... - Differential processing patterns of motor information via striatopallidal and striatonigral projectionsKatsuyuki Kaneda
Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Tokyo 183-8526, Japan
J Neurophysiol 88:1420-32. 2002.... - Transdural doppler ultrasonography monitors cerebral blood flow changes in relation to motor tasksNobuhiko Hatanaka
Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Japan
Cereb Cortex 19:820-31. 2009..Moreover, BFV changes in the SMA depended on task difficulty. The present results indicate that TDD is useful for evaluating regional brain functions... - Activity and distribution patterns of monkey pallidal neurons in response to peripheral nerve stimulationToshikazu Akazawa
Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Tokyo 183-8526, Japan
Neurosci Lett 339:161-5. 2003..The present results indicate that the somatotopical arrangement in the globus pallidus can be outlined based on the neuronal responses to peripheral nerve stimulation... - Reconstruction of movement-related intracortical activity from micro-electrocorticogram array signals in monkey primary motor cortexHidenori Watanabe
Division of Behavioral Development, Department of Developmental Physiology, National Institute for Physiological Sciences, Aichi, Japan
J Neural Eng 9:036006. 2012..55 ± 0.04. A time-frequency analysis of the reconstructed LFP showed clear transition between resting and movements by the monkey. These methods would be a powerful tool with wide-ranging applicability in neuroscience studies... - Reduced pallidal output causes dystoniaAtsushi Nambu
Division of System Neurophysiology, National Institute for Physiological Sciences and Department of Physiological Sciences, Graduate University for Advanced Studies Okazaki, Japan
Front Syst Neurosci 5:89. 2011..Thus, reduced GPi output may cause increased thalamic and cortical activity, resulting in the involuntary movements observed in dystonia... - Functional significance of the cortico-subthalamo-pallidal 'hyperdirect' pathwayAtsushi Nambu
Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, 2 6 Musashidai, Fuchu, Tokyo, Japan
Neurosci Res 43:111-7. 2002..Through this sequential information processing, only the selected motor program is initiated, executed and terminated at the selected timing, whereas other competing programs are canceled... - Origins of GABA(A) and GABA(B) receptor-mediated responses of globus pallidus induced after stimulation of the putamen in the monkeyHitoshi Kita
Department of Anatomy and Neurobiology, College of Medicine, University of Tennessee, Memphis, Tennessee 38163, USA
J Neurosci 26:6554-62. 2006.... - Balance of monosynaptic excitatory and disynaptic inhibitory responses of the globus pallidus induced after stimulation of the subthalamic nucleus in the monkeyHitoshi Kita
Department of Anatomy and Neurobiology, College of Medicine, University of Tennessee, Memphis, Tennessee 38163, USA
J Neurosci 25:8611-9. 2005.... - Serotonin modulates pallidal neuronal activity in the awake monkeyHitoshi Kita
Department of Anatomy and Neurobiology, College of Medicine, University of Tennessee Memphis, Memphis, Tennessee 38163, USA
J Neurosci 27:75-83. 2007..Thus, present results imply that 5-HT modulates synaptic inputs of both pallidal segments and exerts a significant role in movement control... - Two-state membrane potential transitions of striatal spiny neurons as evidenced by numerical simulations and electrophysiological recordings in awake monkeysKatsunori Kitano
Department of Information-Communication Engineering, Tamagawa University, Machida, Tokyo 194-8610, Japan
J Neurosci 22:RC230. 2002..Thus, the membrane potential shifts between the up and down states appear to occur in striatal spiny neurons of the behaving animal...