Kazuki Nakashima

Summary

Affiliation: National Institute of Agrobiological Sciences
Country: Japan

Publications

  1. request reprint
    Nakashima K, Yakabe Y. AMPK activation stimulates myofibrillar protein degradation and expression of atrophy-related ubiquitin ligases by increasing FOXO transcription factors in C2C12 myotubes. Biosci Biotechnol Biochem. 2007;71:1650-6 pubmed
    ..These results indicate that activation of AMPK stimulates myofibrillar protein degradation through the expression of atrogin-1/MAFbx and MuRF1 by increasing FOXO transcription factors in skeletal muscles. ..
  2. request reprint
    Nakashima K, Ishida A, Katsumata M. Atrogin-1/MAFbx, a muscle-specific ubiquitin ligase, is highly expressed in the smooth muscle of the chicken gizzard. Biosci Biotechnol Biochem. 2013;77:1092-5 pubmed
    ..These results indicate that atrogin-1/MAFbx mRNA is highly expressed in the smooth muscle of the chicken gizzard, and that the expression of it is regulated by nutritional conditions. ..
  3. request reprint
    Nakashima K, Yakabe Y, Yamazaki M, Abe H. Effects of fasting and refeeding on expression of atrogin-1 and Akt/FOXO signaling pathway in skeletal muscle of chicks. Biosci Biotechnol Biochem. 2006;70:2775-8 pubmed
    ..These results indicate that refeeding stimulates phosphorylation of Akt/FOXO, resulting in a decrease in atrogin-1 expression in skeletal muscle of chicks. ..