Toru Mori

Summary

Affiliation: National Institute of Infectious Diseases
Country: Japan

Publications

  1. ncbi request reprint Waning of the specific interferon-gamma response after years of tuberculosis infection
    T Mori
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Tokyo, Japan
    Int J Tuberc Lung Dis 11:1021-5. 2007
  2. ncbi request reprint [Some topics of TB research using epidemetric models]
    Toru Mori
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aoba cho, Higashi Murayama shi, Tokyo 189 0002 Japan
    Kekkaku 83:803-9. 2008
  3. ncbi request reprint [Recent problem of skin lesions induced by BCG vaccination]
    Toru Mori
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aobacho, Higashi Murayama shi, Tokyo 189 0002, Japan
    Kekkaku 84:109-15. 2009
  4. ncbi request reprint [Effects of prophylaxis on QuantiFERON TB-2G responses among children]
    Kazue Higuchi
    Immunology Division, Research Institute of Tuberculosis, Japan Anti Tuberculosis Association JATA Matsuyama, Tokyo, Japan
    Kekkaku 83:603-9. 2008
  5. ncbi request reprint Screening for tuberculosis infection using whole-blood interferon-gamma and Mantoux testing among Japanese healthcare workers
    Nobuyuki Harada
    Immunology Division, Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, 3 1 24 Matsuyama, Kiyose, Tokyo 204 8533, Japan
    Infect Control Hosp Epidemiol 27:442-8. 2006
  6. ncbi request reprint Computerized surveillance system of tuberculosis in Japan: its evolution, achievement and challenges
    Masako Ohmori
    The Research Institute of Tuberculosis, Japan Anti Tuberculosis Association JATA, Tokyo, Japan
    Kekkaku 87:15-23. 2012
  7. ncbi request reprint [Basic characteristics of a novel diagnostic method (QuantiFERON TB-2G) for latent tuberculosis infection with the use of Mycobacterium tuberculosis-specific antigens, ESAT-6 and CFP-10]
    Nobuyuki Harada
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association JATA, Tokyo, Japan
    Kekkaku 79:725-35. 2004
  8. doi request reprint Interferon-gamma responses after isoniazid chemotherapy for latent tuberculosis
    Kazue Higuchi
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Tokyo, Japan
    Respirology 13:468-72. 2008
  9. pmc Transmission of specific genotype streptomycin resistant strains of Mycobacterium tuberculosis in the Tokyo Metropolitan Area in Japan
    Akihiro Ohkado
    Department of Epidemiology and Clinical Research, Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Matsuyama 3 1 24, Kiyose, Tokyo, Japan
    BMC Infect Dis 9:138. 2009
  10. ncbi request reprint Use of QuantiFERON-TB Gold to investigate tuberculosis contacts in a high school
    Kazue Higuchi
    Research Institute of Tuberculosis, Tokyo, Japan
    Respirology 12:88-92. 2007

Detail Information

Publications52

  1. ncbi request reprint Waning of the specific interferon-gamma response after years of tuberculosis infection
    T Mori
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Tokyo, Japan
    Int J Tuberc Lung Dis 11:1021-5. 2007
    ..Memory T-cell responses to specific antigens wane over time in subjects with tuberculosis (TB) infection...
  2. ncbi request reprint [Some topics of TB research using epidemetric models]
    Toru Mori
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aoba cho, Higashi Murayama shi, Tokyo 189 0002 Japan
    Kekkaku 83:803-9. 2008
    ..Also, discussions were made on the relevant ways of organizing epidemiological studies in TB, now and in the near future...
  3. ncbi request reprint [Recent problem of skin lesions induced by BCG vaccination]
    Toru Mori
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aobacho, Higashi Murayama shi, Tokyo 189 0002, Japan
    Kekkaku 84:109-15. 2009
    ..To study the recent trends of occurrence of skin lesions as adverse reactions of vaccination with Bacillus Calmette-Guérin...
  4. ncbi request reprint [Effects of prophylaxis on QuantiFERON TB-2G responses among children]
    Kazue Higuchi
    Immunology Division, Research Institute of Tuberculosis, Japan Anti Tuberculosis Association JATA Matsuyama, Tokyo, Japan
    Kekkaku 83:603-9. 2008
    ..To study the effect of treatment of latent tuberculosis infection (LTBI) on QuantiFERON TB-2G (QFT-2G) test results...
  5. ncbi request reprint Screening for tuberculosis infection using whole-blood interferon-gamma and Mantoux testing among Japanese healthcare workers
    Nobuyuki Harada
    Immunology Division, Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, 3 1 24 Matsuyama, Kiyose, Tokyo 204 8533, Japan
    Infect Control Hosp Epidemiol 27:442-8. 2006
    ....
  6. ncbi request reprint Computerized surveillance system of tuberculosis in Japan: its evolution, achievement and challenges
    Masako Ohmori
    The Research Institute of Tuberculosis, Japan Anti Tuberculosis Association JATA, Tokyo, Japan
    Kekkaku 87:15-23. 2012
    ..An important role of the Research Institute of Tuberculosis is to support the planning and execution of TB control with provision of useful epidemiological information from the system...
  7. ncbi request reprint [Basic characteristics of a novel diagnostic method (QuantiFERON TB-2G) for latent tuberculosis infection with the use of Mycobacterium tuberculosis-specific antigens, ESAT-6 and CFP-10]
    Nobuyuki Harada
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association JATA, Tokyo, Japan
    Kekkaku 79:725-35. 2004
    ..To determine the optimum cut-off level of a newly developed method for diagnosing tuberculosis infection based on whole-blood interferon-gamma measurement, and to study the basic characteristics of the method...
  8. doi request reprint Interferon-gamma responses after isoniazid chemotherapy for latent tuberculosis
    Kazue Higuchi
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Tokyo, Japan
    Respirology 13:468-72. 2008
    ..We investigated IFN-gamma responses in subjects with latent TB infection before and after isoniazid (INH) chemotherapy...
  9. pmc Transmission of specific genotype streptomycin resistant strains of Mycobacterium tuberculosis in the Tokyo Metropolitan Area in Japan
    Akihiro Ohkado
    Department of Epidemiology and Clinical Research, Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Matsuyama 3 1 24, Kiyose, Tokyo, Japan
    BMC Infect Dis 9:138. 2009
    ..tuberculosis in the TMA as observed in the above incident, and to identify the possible transmission routes of the strains among people living in urban settings in Japan...
  10. ncbi request reprint Use of QuantiFERON-TB Gold to investigate tuberculosis contacts in a high school
    Kazue Higuchi
    Research Institute of Tuberculosis, Tokyo, Japan
    Respirology 12:88-92. 2007
    ..QuantiFERON-TB Gold (QFT-G) was employed in a contact investigation in a high school to evaluate its performance in adolescents...
  11. doi request reprint Comparison of performance in two diagnostic methods for tuberculosis infection
    Kazue Higuchi
    The Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Kiyose, Tokyo, Japan
    Med Microbiol Immunol 198:33-7. 2009
    ..The difference in the performance between T-SPOT and QFT-G and biological relevance of each system in diagnosing M. tuberculosis infection should be further explored...
  12. ncbi request reprint [Frequency of MDR-TB/XDR-TB strains isolated from chronic pulmonary tuberculosis patients in Japan]
    Yuko Kazumi
    Pathology Division, Mycobacterium Reference Center, Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Tokyo
    Kekkaku 82:891-6. 2007
    ..To observe the frequency of MDR-TB/XDR-TB strains isolated from chronic pulmonary tuberculosis patients in Japan...
  13. ncbi request reprint Analysis of an interferon-gamma release assay for monitoring the efficacy of anti-tuberculosis chemotherapy
    Kiyoko Takayanagi
    Department of Respiratory Medicine, Double Barred Cross Hospital, Japan Anti Tuberculosis Association, Tokyo 204 8533, Japan
    Jpn J Infect Dis 64:133-8. 2011
    ..Although it was shown that anti-tuberculosis treatment generally reduced the specific release of IFN-γ, the effect is so variable that it could be used as a monitor of progress of chemotherapy with great care and reservation...
  14. doi request reprint Relationship between whole-blood interferon-gamma responses and the risk of active tuberculosis
    Kazue Higuchi
    Immunology Division, Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, 3 1 24, Matsuyama, Kiyose, Tokyo 204 8533, Japan
    Tuberculosis (Edinb) 88:244-8. 2008
    ....
  15. ncbi request reprint Specific detection of tuberculosis infection: an interferon-gamma-based assay using new antigens
    Toru Mori
    Research Institute of Tuberculosis, 3 1 24 Matsuyama, Kiyose, Tokyo 204 8533, Japan
    Am J Respir Crit Care Med 170:59-64. 2004
    ..tuberculosis infection was 89.0%. The results demonstrate that the whole blood IFN-gamma assay using CFP-10 and ESAT-6 was highly specific and sensitive for M. tuberculosis infection and was unaffected by BCG vaccination status...
  16. pmc Identification of katG mutations associated with high-level isoniazid resistance in Mycobacterium tuberculosis
    Hiroki Ando
    Department of Infectious Diseases, Research Institute, International Medical Center of Japan, Tokyo, Japan
    Antimicrob Agents Chemother 54:1793-9. 2010
    ..On the basis of our results and known mutations associated with INH resistance, we developed a new hybridization-based line probe assay for rapid detection of INH-resistant M. tuberculosis isolates...
  17. ncbi request reprint [Usefulness of a novel diagnostic method of tuberculosis infection, QuantiFERON TB-2G, in an outbreak of tuberculosis]
    Nobuyuki Harada
    Immunology Division, Research Institute of Tuberculosis, JATA, Tokyo, Japan
    Kekkaku 79:637-43. 2004
    ..The purpose of this study was to evaluate QuantiFERON TB-2G (QFT), a novel method of detecting tuberculosis infection among contacts of a tuberculosis patient by determining the whole-blood interferongamma response to the specific antigens...
  18. ncbi request reprint Assessment of nosocomial transmission of tuberculosis in a psychiatric hospital using a whole blood interferon-gamma assay
    Nobuyuki Harada
    Mycobacterium Reference Center, The Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Tokyo 204 8533, Japan
    Jpn J Infect Dis 61:415-8. 2008
    ....
  19. ncbi request reprint [Analysis of tuberculosis infection among foreigners using QuantiFeron TB-2G test]
    Kazue Higuchi
    Immunology Division, Research Institute of Tuberculosis, JATA, 3 1 24, Matsuyama, Kiyose shi, Tokyo 204 8533, Japan
    Kekkaku 82:515-21. 2007
    ..The purpose of this study was to investigate contacts of a tuberculosis patient among foreigners using QuantiFERON TB-2G (QFT-2G) test...
  20. pmc Comprehensive multicenter evaluation of a new line probe assay kit for identification of Mycobacterium species and detection of drug-resistant Mycobacterium tuberculosis
    Satoshi Mitarai
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Tokyo, Japan
    J Clin Microbiol 50:884-90. 2012
    ..0% and 92.9%, respectively. The kit was able to identify mycobacterial bacilli at the species level, as well as drug-resistant phenotypes, with a high sensitivity and specificity...
  21. ncbi request reprint [Reform of Japan's NTP and its technical perspectives]
    Toru Mori
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association JATA, Tokyo
    Kekkaku 79:587-604. 2004
    ..It is for that reason that the Japanese Society of Tuberculosis should aggressively join the global movement to stop TB along with the general public of Japan...
  22. ncbi request reprint MDR-TB--its characteristics and control in Asia-Pacific rim symposium in USJCMSP 10th international conference on emerging infectious diseases in the Pacific rim
    Toru Mori
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aobacho, Higashimurayama shi, Tokyo 189 0002, Japan
    Tuberculosis (Edinb) 87:S5-9. 2007
    ..These efforts would be more effective if there were further technical innovation in diagnosis and treatment, supported by a strong political commitment...
  23. doi request reprint Usefulness of interferon-gamma release assays for diagnosing TB infection and problems with these assays
    Toru Mori
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, 3 1 24 Matsuyama, Kiyose, Tokyo, 204 8533, Japan
    J Infect Chemother 15:143-55. 2009
    ..However, there are discordant reports that warrant further study...
  24. ncbi request reprint [Trends of tuberculosis researches in Japan and the roles of Kekkaku]
    Toru Mori
    Leprosy Research Center, National Institute of Infectious Diseases
    Kekkaku 84:519-22. 2009
    ..Finally, the roles for Kekkaku as a journal in Japanese language to activate the researches in Japan were discussed and some proposals were made...
  25. ncbi request reprint [Gene-based testing of Mycobacterium tuberculosis]
    Toru Mori
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association
    Nihon Rinsho 63:353-7. 2005
  26. ncbi request reprint [A survey on the onset of tuberculosis in nursing homes]
    Shinji Shishido
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, 3 1 24, Matsuyama, Kiyose shi, Tokyo 204 8533, Japan
    Kekkaku 78:691-7. 2003
    ..To obtain the informations how to promote early detection and prevention of nosocomial infection of tuberculosis in nursing homes for the elderly...
  27. doi request reprint Tuberculosis in the global aging population
    Toru Mori
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Kiyose, Tokyo 204 8533, Japan
    Infect Dis Clin North Am 24:751-68. 2010
    ..This article examines the current and possible future status of TB in the elderly, focusing on epidemiology, risk factors, preventive treatment strategies, and clinical disease...
  28. ncbi request reprint [A new horizon of tuberculosis control and research]
    Toru Mori
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association
    Nihon Rinsho 61:153-9. 2003
    ..Japan's TB control programme is being revised drastically in order to meet the change in the TB epidemiology, aiming at realization of the DOTS concept adapted into the Japanese setting of patient care...
  29. ncbi request reprint [Current status of multidrug-resistant tuberculosis in Japan: a literature review and meta-analysis]
    Toru Mori
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association JATA, Tokyo 204 8533, Japan
    Kekkaku 87:565-75. 2012
    ..This will be a major challenge to the promotion of clinical studies and the control of MDR-TB in Japan...
  30. ncbi request reprint [Tuberculosis and society]
    Toru Mori
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, 3 1 24, Matsuyama, Kiyose shi, Tokyo 204 8533, Japan
    Kekkaku 78:95-100. 2003
    ..Studies in tuberculosis, both basic and epidemiological, as well as multidisciplinary, should be further encouraged from such a point of view, in order to lay such interconnections bare, on which the new control strategy should be based...
  31. ncbi request reprint [The new Tuberculosis Control Program of Japan]
    Toru Mori
    Leprosy Research Center, National Institute of Infectious Diseases
    Kansenshogaku Zasshi 80:345-52. 2006
    ..This reminds us of the United States' remarkable experience of the tuberculosis resurgence in the late 1980's and early 1990's, after 15 years of abandonment of the governmental efforts during 1970s...
  32. ncbi request reprint Evaluation of major membrane protein-II as a tool for serodiagnosis of leprosy
    Yumi Maeda
    Department of Microbiology, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    FEMS Microbiol Lett 272:202-5. 2007
    ..These percentage values were significantly higher than these values obtained for existing phenolic glycolipid-I based methods, suggesting that MMP-II antibody detection would facilitate the diagnosis of leprosy...
  33. ncbi request reprint [Impact of introducing rifampicin on the treatment of tuberculosis during the 1970's in Japan]
    Toru Mori
    Research Institute of Tuberculosis, JATA, 3 1 24, Matsuyama, Kiyose shi, Tokyo 204 8533, Japan
    Kekkaku 88:417-22. 2013
    ..The average duration of tuberculosis chemotherapy in Japan increased year by year throughout the 1960's and reached 49 months by 1973. It then began decreasing slowly in the 1970's and more rapidly after the 1980's...
  34. ncbi request reprint [Investigation on preventive measures of tuberculosis infection and onset of tuberculosis in nursing homes for the aged]
    Shinji Shishido
    Research Institute of Tuberculosis, JATA, 3 1 24, Matsuyama, Kiyose shi, Tokyo 204 8533, Japan
    Kekkaku 77:341-6. 2002
    ..We outlined the essential points for concrete measures to prevent tuberculosis infection in nursing homes for the aged...
  35. ncbi request reprint [Clinical guidelines for tuberculosis of Japan compared with those of other countries]
    Toru Mori
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association
    Nihon Rinsho 69:1400-7. 2011
    ..They also stress the importance of support of patients for treatment completion, but the ways to realize it are delicately different among them...
  36. ncbi request reprint 2. Current tuberculosis problem in Japan and its control
    Toru Mori
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Kiyose, Tokyo
    Intern Med 41:56-7. 2002
  37. ncbi request reprint [Tuberculosis]
    Toru Mori
    Leprosy Research Center, National Institute of Infectious Diseases
    Nihon Rinsho 65:443-8. 2007
  38. ncbi request reprint Correlation between suspended particles in the environmental air and causes of disease among inhabitants: cross-sectional studies using the vital statistics and air pollution data in Japan
    Kazuro Iwai
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, 3 1 24, Matsuyama, Kiyose shi, Tokyo 204 8533, Japan
    Environ Res 99:106-17. 2005
    ..Multivariate regression analysis of confounding factors, smoking rate, population density, and hormone-related factors revealed consistent significance of SPM/cPM(2.5) in these diseases...
  39. ncbi request reprint Development of acquired drug resistance in recurrent tuberculosis patients with various previous treatment outcomes
    T Yoshiyama
    Epidemiology Division, Research Institute of Tuberculosis, Kiyose, Tokyo, Japan
    Int J Tuberc Lung Dis 8:31-8. 2004
    ..Chiang Rai province, Northern Thailand...
  40. ncbi request reprint Tuberculosis drug resistance and treatment outcomes under DOTS settings in large cities in the Philippines
    A Ohkado
    The Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Tokyo, Japan
    Int J Tuberc Lung Dis 10:283-9. 2006
    ..Two large cities in the Philippines...
  41. ncbi request reprint Comparison of erythema and induration as results of tuberculin tests
    M Kimura
    Ministry of Health, Labor, and Welfare, Tokyo, Japan
    Int J Tuberc Lung Dis 9:853-7. 2005
    ..Schoolchildren, tuberculosis (TB) patients, and hospital employees in Tokyo, Japan...
  42. ncbi request reprint An adult patient with hypersensitivity to mosquito bites developing mantle cell lymphoma
    T Mori
    Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
    Int J Hematol 71:259-62. 2000
    ..These findings suggest that the Th1/Th2 imbalance could partly be involved in the pathogenesis of HMB...
  43. ncbi request reprint Prevalence of drug-resistant tuberculosis in an HIV endemic area in northern Thailand
    T Yoshiyama
    Research Institute of Tuberculosis, Kiyose Tokyo, Japan
    Int J Tuberc Lung Dis 5:32-9. 2001
    ..Chiang Rai Province in Northern Thailand, where human immunodeficiency virus (HIV) infection has been prevalent since the 1990s...
  44. ncbi request reprint The national tuberculosis drug resistance survey in Cambodia, 2000-2001
    N Yamada
    The Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Tokyo, Japan
    Int J Tuberc Lung Dis 11:1321-7. 2007
    ..Cambodia has a high incidence of tuberculosis (TB). Hospital-based DOTS was predominant throughout the country from 1994 to 2002...
  45. ncbi request reprint Molecular epidemiology of Mycobacterium tuberculosis in an urban area in Japan, 2002-2006
    A Ohkado
    Research Institute of Tuberculosis, Japan Anti Tuberculosis Association, Kiyose, Japan
    Int J Tuberc Lung Dis 12:548-54. 2008
    ..Shinjuku City, Tokyo, Japan...
  46. ncbi request reprint [Where do we stand with BCG vaccination programme in Japan?]
    T Mori
    Tuberculosis Research Institute, Japan Anti Tuberculosis Association, Tokyo, Japan
    Kekkaku 76:385-97. 2001
    ..This balance was compared with that of Sweden around 1975, when the program was discontinued. The comparison clearly showed that the cost-effectiveness of the program in Japan today in superior to that of Sweden in 1975...
  47. ncbi request reprint Current epidemiological trend of tuberculosis in Japan
    M Ohmori
    The Research Institute of Tuberculosis, Tokyo, Japan
    Int J Tuberc Lung Dis 6:415-23. 2002
    ..To observe the recent epidemiological trend of tuberculosis and to determine the factors related to the deteriorating trend in incidence and mortality rates in Japan...
  48. ncbi request reprint [Susceptibilities of bacteria isolated from patients with lower respiratory infectious diseases to antibiotics (1999)]
    K Shimada
    Tokyo Senbai Hospital
    Jpn J Antibiot 54:331-64. 2001
    ..However, that of H. influenzae was decreased to 7.1% after administration within 3 days, and many H. influenzae were isolated after completion of administration as 21.4%...
  49. ncbi request reprint Nationwide survey on the prevalence of anti-tuberculosis drug resistance in the Republic of Yemen, 2004
    A Al-Akhali
    National Tuberculosis Reference Laboratory, National Tuberculosis Institute, Ministry of Public Health and Population, Sana a, Yemen
    Int J Tuberc Lung Dis 11:1328-33. 2007
    ..To determine the prevalence of resistance to the four major anti-tuberculosis drugs, isoniazid, rifampicin, streptomycin and ethambutol, in Yemen...
  50. ncbi request reprint The nationwide tuberculosis drug resistance survey in Mongolia, 1999
    G Tsogt
    National Tuberculosis Centre, Ulaanbaatar, Mongolia
    Int J Tuberc Lung Dis 6:289-94. 2002
    ..Mongolia, a country in the Western Pacific Region burdened with many cases of tuberculosis, with rapid expansion of DOTS over the last several years...
  51. ncbi request reprint Identification of a novel gene, OASIS, which encodes for a putative CREB/ATF family transcription factor in the long-term cultured astrocytes and gliotic tissue
    Y Honma
    Department of Cell Science, Institute of Biomedical Sciences, 1 Hikarigaoka, Fukushima City, Fukushima 960 1295, Japan
    Brain Res Mol Brain Res 69:93-103. 1999
    ..The distribution pattern of the OASIS-positive cells in the injured cortex was very similar to that of the glial fibrillary acidic protein (GFAP)-positive cells. These results suggest that OASIS protein may play a role in gliotic events...
  52. pmc Independence of circadian timing from cell division in cyanobacteria
    T Mori
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235, USA
    J Bacteriol 183:2439-44. 2001
    ....