M Matsuoka

Summary

Affiliation: National Institute of Infectious Diseases
Country: Japan

Publications

  1. ncbi request reprint Recent advances in the molecular epidemiology of leprosy
    Masanori Matsuoka
    Department of Bioregulation, Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aobacho, Higashimurayama shi, Tokyo 189 0002, Japan
    Nihon Hansenbyo Gakkai Zasshi 78:67-73. 2009
  2. ncbi request reprint [Collaboration between Korea and Japan for basic research on leprosy]
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    Nihon Hansenbyo Gakkai Zasshi 81:205-7. 2012
  3. ncbi request reprint A second case of multidrug-resistant Mycobacterium leprae isolated from a Japanese patient with relapsed lepromatous leprosy
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aobacho, Higashimurayama, Tokyo, 189 0002, Japan
    Int J Lepr Other Mycobact Dis 71:240-3. 2003
  4. pmc Genotyping of Mycobacterium leprae on the basis of the polymorphism of TTC repeats for analysis of leprosy transmission
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo
    J Clin Microbiol 42:741-5. 2004
  5. ncbi request reprint [Molecular epidemiology of the leprosy]
    Masanori Matsuoka
    National Institute of Infectious Diseases, Leprosy Research Center, 4 2 1, Aobacho, Higashimurayama, Tokyo, 189 0002, Japan
    Nihon Hansenbyo Gakkai Zasshi 73:7-14. 2004
  6. doi request reprint A novel method for simple detection of mutations conferring drug resistance in Mycobacterium leprae, based on a DNA microarray, and its applicability in developing countries
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    J Med Microbiol 57:1213-9. 2008
  7. ncbi request reprint The frequency of drug resistance mutations in Mycobacterium leprae isolates in untreated and relapsed leprosy patients from Myanmar, Indonesia and the Philippines
    Masanori Matsuoka
    Leprosy Research Centre, National Institute of Infectious Diseases, Tokyo, Japan
    Lepr Rev 78:343-52. 2007
  8. ncbi request reprint Polymorphism in the rpoT gene in Mycobacterium leprae isolates obtained from Latin American countries and its possible correlation with the spread of leprosy
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aobacho, Higashimurayama shi, 189 0002 Tokyo, Japan
    FEMS Microbiol Lett 243:311-5. 2005
  9. ncbi request reprint Genotypic analysis of Mycobacterium leprae isolates from Japan and other Asian countries reveals a global transmission pattern of leprosy
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    FEMS Microbiol Lett 261:150-4. 2006
  10. ncbi request reprint Various genotypes of Mycobacterium leprae from Mexico reveal distinct geographic distribution
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aobacho, Higashimurayama shi, Tokyo, 189 0002, Japan
    Lepr Rev 80:322-6. 2009

Detail Information

Publications39

  1. ncbi request reprint Recent advances in the molecular epidemiology of leprosy
    Masanori Matsuoka
    Department of Bioregulation, Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aobacho, Higashimurayama shi, Tokyo 189 0002, Japan
    Nihon Hansenbyo Gakkai Zasshi 78:67-73. 2009
    ..We expect that the transmission of leprosy can be fully analyzed by the application of these new methodologies...
  2. ncbi request reprint [Collaboration between Korea and Japan for basic research on leprosy]
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    Nihon Hansenbyo Gakkai Zasshi 81:205-7. 2012
    ..The possibility of future collaboration between Korea and Japan to solve remaining problems in the clinical field was discussed and a course of action for collaboration was deliberated...
  3. ncbi request reprint A second case of multidrug-resistant Mycobacterium leprae isolated from a Japanese patient with relapsed lepromatous leprosy
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aobacho, Higashimurayama, Tokyo, 189 0002, Japan
    Int J Lepr Other Mycobact Dis 71:240-3. 2003
    ..The drug resistant profile of the isolated strain was confirmed by the mouse footpad method and the identification of mutations in genes previously shown to be associated with resistance to each drug was made...
  4. pmc Genotyping of Mycobacterium leprae on the basis of the polymorphism of TTC repeats for analysis of leprosy transmission
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo
    J Clin Microbiol 42:741-5. 2004
    ..A limited discriminative capacity of the TTC polymorphism in the epidemiological analysis implies the need of searching other useful polymorphic loci for detailed subdivision of clinical isolates...
  5. ncbi request reprint [Molecular epidemiology of the leprosy]
    Masanori Matsuoka
    National Institute of Infectious Diseases, Leprosy Research Center, 4 2 1, Aobacho, Higashimurayama, Tokyo, 189 0002, Japan
    Nihon Hansenbyo Gakkai Zasshi 73:7-14. 2004
    ..leprae rpoT genotypes and prehistoric spread of the leprosy by genotyping based on the genomic polymorphism are introduced...
  6. doi request reprint A novel method for simple detection of mutations conferring drug resistance in Mycobacterium leprae, based on a DNA microarray, and its applicability in developing countries
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    J Med Microbiol 57:1213-9. 2008
    ..This is a rapid and simple method for the simultaneous susceptibility testing of three front-line drugs for leprosy, and solves the problems of previously reported methods...
  7. ncbi request reprint The frequency of drug resistance mutations in Mycobacterium leprae isolates in untreated and relapsed leprosy patients from Myanmar, Indonesia and the Philippines
    Masanori Matsuoka
    Leprosy Research Centre, National Institute of Infectious Diseases, Tokyo, Japan
    Lepr Rev 78:343-52. 2007
    ..The magnitude of drug resistance in Mycobacterium leprae to dapsone, rifampicin, and ofloxacin was studied in three Southeast Asian countries with a high prevalence of leprosy...
  8. ncbi request reprint Polymorphism in the rpoT gene in Mycobacterium leprae isolates obtained from Latin American countries and its possible correlation with the spread of leprosy
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aobacho, Higashimurayama shi, 189 0002 Tokyo, Japan
    FEMS Microbiol Lett 243:311-5. 2005
    ..leprae harboured by the various human races that moved to the American continent, as has been demonstrated in other infectious diseases...
  9. ncbi request reprint Genotypic analysis of Mycobacterium leprae isolates from Japan and other Asian countries reveals a global transmission pattern of leprosy
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    FEMS Microbiol Lett 261:150-4. 2006
    ..Type 4, TTC, with three copies of 6 bp, was detected only from Japanese Brazilians. The results indicate that infection occurred in Brazil and the disease developed later in Japan...
  10. ncbi request reprint Various genotypes of Mycobacterium leprae from Mexico reveal distinct geographic distribution
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aobacho, Higashimurayama shi, Tokyo, 189 0002, Japan
    Lepr Rev 80:322-6. 2009
    ....
  11. ncbi request reprint Drug resistance in leprosy
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, Higashimurayama, Tokyo, Japan
    Jpn J Infect Dis 63:1-7. 2010
    ..New methodologies to test susceptibility to anti-leprosy drugs instead of the traditional mouse footpad method are introduced. Awareness of the need to monitor drug resistance to prevent the spread of resistant cases is emphasized...
  12. ncbi request reprint A Mycobacterium leprae isolate resistant to dapsone, rifampin, ofloxacin and sparfloxacin
    M Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1 Aobacho, Higashimurayama shi, 189 0002 Tokyo, Japan
    Int J Lepr Other Mycobact Dis 68:452-5. 2000
    ..Mutations were identified in the genes associated with resistance to these drugs. The risk of the emergence of leprosy with multidrug resistance is emphasized...
  13. ncbi request reprint [Our role in sentinel surveillance for drug resistance in leprosy by global leprosy programme]
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    Nihon Hansenbyo Gakkai Zasshi 80:287-91. 2011
    ..Possible contribution of Japanese researchers to global leprosy control in the future were discussed on the base of circumstances of the project and our assignment in the sueveillance...
  14. ncbi request reprint [How to concern to international cooperation for the basic researcher]
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aoba cho, Higashimurayama, Tokyo, 189 0002, Japan
    Nihon Hansenbyo Gakkai Zasshi 71:197-200. 2002
    ..Prevention of further reduction of research activity was stressed...
  15. ncbi request reprint [Novel method for simple detection of mutations conferring drug resistance in Mycobacterium leprae, based on a DNA microarray, and its applicability in developing countries]
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, Higashimurayama, Tokyo, Japan
    Nihon Hansenbyo Gakkai Zasshi 79:257-61. 2010
    ..The results obtained with the kit at those laboratories were highly concordant with results of sequencing. The method is feasible for the testing by local person in areas with high prevalence of leprosy...
  16. ncbi request reprint History and characteristics of isolates maintained at the leprosy research center
    Masanori Matsuoka
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    Nihon Hansenbyo Gakkai Zasshi 79:247-56. 2010
    ..The Leprosy Research Center provides bacillary materials as experimental resources at researchers' request...
  17. pmc Multidrug resistant Mycobacterium leprae from patients with leprosy
    S Maeda
    Leprosy Research Center, National Institute of Infectious Diseases, Higashimurayama-shi, Tokyo 189-0002, Japan
    Antimicrob Agents Chemother 45:3635-9. 2001
    ..Thirteen isolates (14.8%) showed representative mutations in more than two genes, suggesting the emergence of multidrug-resistant M. leprae...
  18. pmc Diversity of potential short tandem repeats in Mycobacterium leprae and application for molecular typing
    Liangfen Zhang
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aobacho, Higashimurayama shi, Tokyo 189 0002, Japan
    J Clin Microbiol 43:5221-9. 2005
    ....
  19. ncbi request reprint Diaminodiphenylsulfone resistance of Mycobacterium leprae due to mutations in the dihydropteroate synthase gene
    M Kai
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    FEMS Microbiol Lett 177:231-5. 1999
    ..This is the first paper which links the mutations in DHPS and sulfonamide resistance in M. leprae. This finding is medically and socially relevant, since leprosy is still a big problem in certain regions...
  20. doi request reprint Enhanced activation of T lymphocytes by urease-deficient recombinant bacillus Calmette-Guérin producing heat shock protein 70-major membrane protein-II fusion protein
    Tetsu Mukai
    Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    J Immunol 185:6234-43. 2010
    ..leprae than vector control BCG. These results indicate that the triple combination of HSP70, MMP-II, and urease depletion may provide a useful tool for inducing better activation of naive T cells...
  21. ncbi request reprint A mutation at codon 516 in the rpoB gene of Mycobacterium leprae confers resistance to rifampin
    Liangfen Zhang
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    Int J Lepr Other Mycobact Dis 72:468-72. 2004
    ....
  22. pmc Inhibition of the multiplication of Mycobacterium leprae by vaccination with a recombinant M. bovis BCG strain that secretes major membrane protein II in mice
    Y Maeda
    Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Higashimurayama, Tokyo 189 0002, Japan
    Clin Vaccine Immunol 16:1399-404. 2009
    ..BCG-SM inhibited the multiplication of M. leprae in the footpads of C57BL/6J mice more efficiently than BCG-pMV. These results indicate that a BCG strain that secretes MMP-II could be a better vaccine candidate for leprosy...
  23. pmc Mycobacterium leprae infection in monocyte-derived dendritic cells and its influence on antigen-presenting function
    Ken Hashimoto
    Department of Microbiology, Leprosy Research Center, National Institute of Infectious Diseases, Higashimurayama, Tokyo, Japan
    Infect Immun 70:5167-76. 2002
    ..M. leprae is a unique pathogen which remains resistant to DC-mediated T-cell immunity, at least in the early stages of infection...
  24. ncbi request reprint Effect of hsp65 DNA vaccination carrying immunostimulatory DNA sequences (CpG motifs) against Mycobacterium leprae multiplication in mice
    Hiroko Nomaguchi
    Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1 Aobacho, Higashimurayama, Tokyo, Japan
    Int J Lepr Other Mycobact Dis 70:182-90. 2002
    ..leprae. These results suggest that a DNA containing M. leprae-derived hsp65 and immunostimulatory sequences might be a potent vaccine candidate against M. leprae infection...
  25. ncbi request reprint IL-10 treatment of macrophages bolsters intracellular survival of Mycobacterium leprae
    Yasuo Fukutomi
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    Int J Lepr Other Mycobact Dis 72:16-26. 2004
    ..Acid fast staining and transmission electron microscopy (TEM) of intracellular M. leprae revealed visible elongation of bacilli cultured under the above ideal conditions...
  26. ncbi request reprint Temperature dependency for survival of Mycobacterium leprae in macrophages
    Yasuo Fukutomi
    Department of Microbiology, Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1, Aoba cho, Higashimurayama shi, Tokyo 189 0002, Japan
    Nihon Hansenbyo Gakkai Zasshi 78:7-16. 2009
    ..However, the viability of M. leprae was almost lost within 2 weeks if cultured at 37 degrees C. These data suggest that temperature is a crucial factor for the survival of M. leprae in host cells...
  27. ncbi request reprint [Current advances in leprosy research activities]
    Masahiko Makino
    Department of Microbiology, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo 189 0002, Japan
    Nihon Hansenbyo Gakkai Zasshi 74:3-22. 2005
    ..Leprosy caused by M. leprae is still unclear on various aspects including transmission, immunology, nerve damage etc. Here we introduce the recent advances in the field of basic leprosy research...
  28. ncbi request reprint [Basic evaluation for new antimicrobial susceptibility testing of Mycobacterium leprae by bioluminescence assay (ATP method)]
    Toshio Yamazaki
    Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    Nihon Hansenbyo Gakkai Zasshi 75:227-37. 2006
    ..ATP method may be useful for the determination of drug susceptibility ofM. leprae...
  29. ncbi request reprint [Current practice of genetic diagnosis for Mycobacterium leprae]
    Norihisa Ishii
    Department of Bioregulation, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    Nihon Hansenbyo Gakkai Zasshi 75:261-4. 2006
    ..These examinations include histopathology, serum antibody titers (anti-PGL-I antibody), PCR test and bioactivity of anti-bacterial agents...
  30. ncbi request reprint Upregulation of T-cell-stimulating activity of mycobacteria-infected macrophages
    H Kimura
    Department of Microbiology, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    Scand J Immunol 60:278-86. 2004
    ..These results suggest that the induction of phenotypic changes in macrophages can lead to the upregulation of host defence activity against M. leprae...
  31. doi request reprint Induction of cross-priming of naive CD8+ T lymphocytes by recombinant bacillus Calmette-Guerin that secretes heat shock protein 70-major membrane protein-II fusion protein
    Tetsu Mukai
    Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    J Immunol 183:6561-8. 2009
    ..These results indicate that BCG-70M activated DC, CD4(+) T cells, and CD8(+) T cells, and the combination of HSP70 and MMP-II may be useful for inducing better T cell activation...
  32. ncbi request reprint Association of interleukin-18 gene single-nucleotide polymorphisms with susceptibility to inflammatory bowel disease
    Y Aizawa
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan
    Tissue Antigens 65:88-92. 2005
    ..The haplotype estimation, according to the E-M algorithm, suggested that TACGT is closely associated with IBD, especially with CD. It was concluded that SNPs at the 5'-end of IL-18 gene might be closely related to the etiology of IBD...
  33. ncbi request reprint Human proliferative sparganosis. A new Japanese case
    T Nakamura
    Department of Pathology, Toranomon Hospital, Tokyo, Japan
    Am J Clin Pathol 94:224-8. 1990
    ..These morphologic findings confirmed the nature of maldifferentiated plerocercoid. The serologic data suggested a close relation between Sparganum proliferum and Spirometra erinacei...
  34. ncbi request reprint Profiles of the mRNA expression by macrophages infected with Mycobacterium leprae and Mycobacterium avium complex
    Toshiaki Shimizu
    Department of Microbiology and Immunology, Shimane Medical University, Izumo, Shimane 693 8501, Japan
    Int J Lepr Other Mycobact Dis 70:250-9. 2002
    ..leprae and MAC organisms with murine peritoneal M phi s in terms of the activation of signal transduction pathways for expression of some kinds of immunoregulatory cytokines and immunoprotective enzymes...
  35. ncbi request reprint [DNA microarray based rapid drug susceptibility test for Mycobacterium leprae]
    Yasuhiko Suzuki
    Department of Global Epidemiology, Hokkaido University Research Center for Zoonosis Control, Hokkaido, Japan
    Nihon Hansenbyo Gakkai Zasshi 75:271-7. 2006
    ..The low density oligonucleotide array described in this paper will open the new perspectives in terms of patient management for leprosy with low cost requirement...
  36. ncbi request reprint Recombinant Mycobacterium leprae protein associated with entry into mammalian cells of respiratory and skin components
    Naoya Sato
    Department of Dermatology, Graduate School of Medical Science, Kitasato University, 1 15 1 Kitasato, Sagamihara, Kanagawa 228 8555, Japan
    J Dermatol Sci 46:101-10. 2007
    ..The M. leprae genome contains mce1A gene, which encodes a putative mammalian cell entry protein. However, to date, there have been no functional analyses of the M. leprae mce1A gene product...
  37. ncbi request reprint Degradation process of Mycobacterium leprae cells in infected tissue examined by the freeze-substitution method in electron microscopy
    Kazunobu Amako
    Department of Bacteriology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Fukuoka 812 8582, Japan
    Microbiol Immunol 47:387-94. 2003
    ..The peptidoglycan layer was found to remain intact in these cell groups...
  38. ncbi request reprint Comparative studies of the cell structures of Mycobacterium leprae and M. tuberculosis using the electron microscopy freeze-substitution technique
    Akemi Takade
    Department of Bacteriology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Fukuoka 812 8582, Japan
    Microbiol Immunol 47:265-70. 2003
    ..The cell widths measured on electron micrographs were 0.44 microm for M. tuberculosis and 0.38 microm for M. leprae. The peptidoglycan layer of M. leprae was 4-5 nm, while the corresponding layer of M. tuberculosis was 10-15 nm...
  39. ncbi request reprint [Today and tomorrow of International Medical Cooperation for Hansen's disease]
    Masanao Makino
    Nihon Hansenbyo Gakkai Zasshi 71:137-41. 2002