Y Masuo

Summary

Affiliation: National Institute of Advanced Industrial Science and Technology
Country: Japan

Publications

  1. ncbi request reprint Behavioural characteristics and gene expression in the hyperactive wiggling (Wig) rat
    Yoshinori Masuo
    Human Stress Signal Research Center, National Institute of Advanced Industrial Science and Technology, Tsukuba West, 16 1 Onogawa, Tsukuba 305 8569, Japan
    Eur J Neurosci 25:3659-66. 2007
  2. ncbi request reprint Motor activity and gene expression in rats with neonatal 6-hydroxydopamine lesions
    Yoshinori Masuo
    Human Stress Signal Research Center, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Japan
    J Neurochem 91:9-19. 2004
  3. pmc Effects of neonatal treatment with 6-hydroxydopamine and endocrine disruptors on motor activity and gene expression in rats
    Yoshinori Masuo
    National Institute of Advanced Industrial Science and Technology, Tsukuba Central 6, 1 1 1 Higashi, Tsukuba 305 8566, Japan
    Neural Plast 11:59-76. 2004
  4. pmc Ultra low-dose radiation: stress responses and impacts using rice as a grass model
    Randeep Rakwal
    Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Int J Mol Sci 10:1215-25. 2009
  5. ncbi request reprint Motor hyperactivity caused by a deficit in dopaminergic neurons and the effects of endocrine disruptors: a study inspired by the physiological roles of PACAP in the brain
    Yoshinori Masuo
    Human Stress Signal Research Center, National Institute of Advanced Industrial Science and Technology, Tsukuba Central 6, 1 1 1 Higashi, Tsukuba 305 8566, Japan
    Regul Pept 123:225-34. 2004
  6. ncbi request reprint Vasoactive intestinal contractor/endothelin-2 gene expression in the murine central nervous system
    Yoshinori Masuo
    International Patent Organism Depositary, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Biochem Biophys Res Commun 300:661-8. 2003
  7. ncbi request reprint Effects of neonatal 6-hydroxydopamine lesion on the gene expression profile in young adult rats
    Yoshinori Masuo
    International Patent Organism Depositary, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Neurosci Lett 335:124-8. 2002
  8. ncbi request reprint Hippocalcin protects hippocampal neurons against excitotoxin damage by enhancing calcium extrusion
    Y Masuo
    Department of Physiology, Toho University School of Medicine, 5 21 16 Ohmori nishi, Ohta ku, Tokyo 143 8540, Japan
    Neuroscience 145:495-504. 2007
  9. ncbi request reprint Dicyclohexylphthalate causes hyperactivity in the rat concomitantly with impairment of tyrosine hydroxylase immunoreactivity
    Masami Ishido
    National Institute for Environmental Studies, Tsukuba, Japan
    J Neurochem 91:69-76. 2004
  10. doi request reprint Proteomic characterization of the striatum and midbrain treated with 6-hydroxydopamine: alteration of 58-kDa glucose-regulated protein and C/EBP homologous protein
    Yoko Ogawa Akazawa
    Health Technology Research Center, National Institute of Advanced Industrial Science and Technology AIST, Kansai Center, Ikeda, Osaka, Japan
    Free Radic Res 44:410-21. 2010

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Behavioural characteristics and gene expression in the hyperactive wiggling (Wig) rat
    Yoshinori Masuo
    Human Stress Signal Research Center, National Institute of Advanced Industrial Science and Technology, Tsukuba West, 16 1 Onogawa, Tsukuba 305 8569, Japan
    Eur J Neurosci 25:3659-66. 2007
    ..Wig rats may provide a model of attention-deficit hyperactivity disorder in which treatment with psychostimulants accelerate the hyperactivity...
  2. ncbi request reprint Motor activity and gene expression in rats with neonatal 6-hydroxydopamine lesions
    Yoshinori Masuo
    Human Stress Signal Research Center, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Japan
    J Neurochem 91:9-19. 2004
    ..Several classes of neurotransmitters, including dopamine and peptides, may be involved in compensatory mechanisms during early adulthood. These data may prompt further neurochemical investigations in hyperkinetic disorders...
  3. pmc Effects of neonatal treatment with 6-hydroxydopamine and endocrine disruptors on motor activity and gene expression in rats
    Yoshinori Masuo
    National Institute of Advanced Industrial Science and Technology, Tsukuba Central 6, 1 1 1 Higashi, Tsukuba 305 8566, Japan
    Neural Plast 11:59-76. 2004
    ..The results suggest that neonatal treatment with environmental chemicals can generate an animal model of attention-deficit hyperactivity disorder, in which clinical symptoms are pervasive...
  4. pmc Ultra low-dose radiation: stress responses and impacts using rice as a grass model
    Randeep Rakwal
    Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Int J Mol Sci 10:1215-25. 2009
    ..Results suggest the usefulness of the rice model in studying ultra low-dose radiation response/s...
  5. ncbi request reprint Motor hyperactivity caused by a deficit in dopaminergic neurons and the effects of endocrine disruptors: a study inspired by the physiological roles of PACAP in the brain
    Yoshinori Masuo
    Human Stress Signal Research Center, National Institute of Advanced Industrial Science and Technology, Tsukuba Central 6, 1 1 1 Higashi, Tsukuba 305 8566, Japan
    Regul Pept 123:225-34. 2004
    ..These results suggest that the mechanisms underlying the induction of motor hyperactivity and/or compensatory changes in young adult rats might differ between 6-OHDA and endocrine disruptors...
  6. ncbi request reprint Vasoactive intestinal contractor/endothelin-2 gene expression in the murine central nervous system
    Yoshinori Masuo
    International Patent Organism Depositary, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Biochem Biophys Res Commun 300:661-8. 2003
    ..These results suggest that VIC/ET-2 may have certain physiological roles that differ from those of ET-1 in the brain and pituitary gland...
  7. ncbi request reprint Effects of neonatal 6-hydroxydopamine lesion on the gene expression profile in young adult rats
    Yoshinori Masuo
    International Patent Organism Depositary, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Neurosci Lett 335:124-8. 2002
    ..These results suggest that 6-hydroxydopamine-treated rats may partly mimic human hyperkinesia not only in behavior but also in gene expression...
  8. ncbi request reprint Hippocalcin protects hippocampal neurons against excitotoxin damage by enhancing calcium extrusion
    Y Masuo
    Department of Physiology, Toho University School of Medicine, 5 21 16 Ohmori nishi, Ohta ku, Tokyo 143 8540, Japan
    Neuroscience 145:495-504. 2007
    ..These results suggest that hippocalcin plays an important role in calcium extrusion from neurons and, in turn, helps to protect them against calcium-dependent excitotoxin damage in the hippocampus...
  9. ncbi request reprint Dicyclohexylphthalate causes hyperactivity in the rat concomitantly with impairment of tyrosine hydroxylase immunoreactivity
    Masami Ishido
    National Institute for Environmental Studies, Tsukuba, Japan
    J Neurochem 91:69-76. 2004
    ..We conclude that DCHP affected the developing rat brain, resulting in hyperactivity, probably as a result of degeneration of mesencephalic tyrosine hydroxylase rather than alteration of the level of gene expression...
  10. doi request reprint Proteomic characterization of the striatum and midbrain treated with 6-hydroxydopamine: alteration of 58-kDa glucose-regulated protein and C/EBP homologous protein
    Yoko Ogawa Akazawa
    Health Technology Research Center, National Institute of Advanced Industrial Science and Technology AIST, Kansai Center, Ikeda, Osaka, Japan
    Free Radic Res 44:410-21. 2010
    ..Collectively, these findings suggest that ER stress involving the alteration of Grp58 and CHOP play a significant role in the induction of insults by 6-OHDA in vivo...
  11. ncbi request reprint Hippocalcin-deficient mice display a defect in cAMP response element-binding protein activation associated with impaired spatial and associative memory
    M Kobayashi
    Department of Physiology, Toho University School of Medicine, 5 21 16 Ohmori nishi, Ohta ku, Tokyo 143 8540, Japan
    Neuroscience 133:471-84. 2005
    ..These results suggest that hippocalcin plays a crucial role in the Ca(2+)-signaling pathway that underlies long-lasting neural plasticity and that leads to spatial and associative memory...
  12. ncbi request reprint Transcriptome of pituitary adenylate cyclase-activating polypeptide-differentiated PC12 cells
    Masami Ishido
    Endocrine Disruptors and Dioxin Research Projects, National Institute for Environmental Studies, 16 2 Onogawa, Tsukuba, Ibaraki 305 8506, Japan
    Regul Pept 123:15-21. 2004
    ..Thus, in this study the transcriptome of PACAP-differentiated PC12 was established, leading to the elucidation of the molecular mechanism of neuritogenesis by the neuropeptide...
  13. doi request reprint Proteomics- and transcriptomics-based screening of differentially expressed proteins and genes in brain of Wig rat: a model for attention deficit hyperactivity disorder (ADHD) research
    Misato Hirano
    Human Stress Signal Research Center HSS, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba West, 16 1 Onogawa, Tsukuba 305 8569, Japan
    J Proteome Res 7:2471-89. 2008
    ....
  14. ncbi request reprint Differential circadian expression of endothelin-1 mRNA in the rat suprachiasmatic nucleus and peripheral tissues
    Shuji Hanai
    Clock Cell Biology Research Group, Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology AIST, Central 6, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Neurosci Lett 377:65-8. 2005
    ..The results are the first description of the circadian expression of ET-1 mRNA. The diversity of rhythmic expressions among the SCN, whole brain, lungs and heart suggests that ET-1 has different functions in these tissues...
  15. doi request reprint Transcriptomic analysis of rat brain tissue following gamma knife surgery: early and distinct bilateral effects in the un-irradiated striatum
    Misato Hirano
    Health Technology Research Center, National Institute of Advanced Industrial Science and Technology AIST West, 16 1 Onogawa, Tsukuba, 305 8569, Ibaraki, Japan
    Mol Cells 27:263-8. 2009
    ..Results of semiquantitative, confirmatory RT-PCR and western blot analyses suggested that gamma-irradiation caused cellular damage, including oxidative stress, in the striata of both hemispheres of the brains of treated animals...
  16. ncbi request reprint Bisphenol A causes hyperactivity in the rat concomitantly with impairment of tyrosine hydroxylase immunoreactivity
    Masami Ishido
    Endocrine Disruptors and Dioxin Research Projects, National Institute for Environmental Studies, Tsukuba, Japan
    J Neurosci Res 76:423-33. 2004
    ..We conclude that bisphenol A affected central dopaminergic system activity, resulting in hyperactivity due most likely to a large reduction of tyrosine hydroxylase activity in the midbrain...
  17. ncbi request reprint Molecular mechanisms of 6-hydroxydopamine-induced cytotoxicity in PC12 cells: involvement of hydrogen peroxide-dependent and -independent action
    Yoshiro Saito
    Human Stress Signal Research Center, National Institute of Advanced Industrial Science and Technology, Kansai Center, 1 8 31 Midorigaoka, Ikeda, Osaka 563 8577, Japan
    Free Radic Biol Med 42:675-85. 2007
    ..These findings may contribute to explain the importance of generated H2O2 and secondary products as a second messenger of 6-OHDA-induced cell death signal linked to Parkinson's disease...
  18. ncbi request reprint Rapid detection of mycoplasma contamination in cell cultures using SYBR Green-based real-time polymerase chain reaction
    Yoko Ishikawa
    International Patent Organism Depositary, AIST, Tsukuba, Ibaraki, Japan
    In Vitro Cell Dev Biol Anim 42:63-9. 2006
    ..Thus, this technique, which is simple, rapid, and sensitive enough for practical application, is suitable for handling many samples and for routine screening for mycoplasma contamination of cell cultures...
  19. doi request reprint Omic analyses unravels global molecular changes in the brain and liver of a rat model for chronic Sake (Japanese alcoholic beverage) intake
    Yoshinori Masuo
    Health Technology Research Center HTRC, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Japan
    Electrophoresis 30:1259-75. 2009
    ..Our results provide a detailed inventory of molecular components of both brain and liver after Sake intake, and may help to better understand effects of chronic Sake drinking...
  20. ncbi request reprint Effect of aging on gene expression rates of endothelin-1 and endothelin-2/vasoactive intestinal contractor in ethanol-induced gastric mucosal injury of the mouse
    Takaharu Kozakai
    Institute of Molecular and Cell Biology, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305 8566, Japan
    Clin Sci (Lond) 103:455S-458S. 2002
    ..We therefore suggest that regulation of gene expression of these two genes differs during the course of aging...
  21. ncbi request reprint Increased gene expression of endothelin-1 and vasoactive intestinal contractor/endothelin-2 in the mammary gland of lactating mice
    Takaharu Kozakai
    Laboratory of Gene Function Analysis, Institute of Molecular and Cell Biology, National Institute of Advanced Industrial Science and Technology AIST, Central 6, 1 1 1 Higashi, Tsukuba, 305 8566, Ibaraki, Japan
    Biochem Biophys Res Commun 297:1339-43. 2002
    ..The observed increase in ET-1 expression in differentiated epithelial cells suggests physiological roles for ET-1, including milk production and secretion in the mammary gland of lactating mice...
  22. doi request reprint Elevation of oxidized DJ-1 in the brain and erythrocytes of Parkinson disease model animals
    Yoko Ogawa Akazawa
    Health Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Ikeda, Osaka, Japan
    Neurosci Lett 483:201-5. 2010
    ..These results suggest that the oxidative modification of DJ-1 in the brain and erythrocytes is involved in the pathogenesis of PD in animal models...
  23. doi request reprint Integrated transcriptomics, proteomics, and metabolomics analyses to survey ozone responses in the leaves of rice seedling
    Kyoungwon Cho
    Environmental Biology Division, National Institute for Environmental Studies, Tsukuba, Ibaraki 305 8506, Japan
    J Proteome Res 7:2980-98. 2008
    ..This systematic survey showed that O(3) triggers a chain reaction of altered gene, protein and metabolite expressions involved in multiple cellular processes in rice...
  24. ncbi request reprint Gel-based proteomics of unilateral irradiated striatum after gamma knife surgery
    Misato Hirano
    Human Stress Signal Research Center HSS, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba West, 16 1 Onogawa, Tsukuba 305 8569, Japan
    J Proteome Res 6:2656-68. 2007
    ..Taken together, these results indicate that unilateral irradiation during GKS triggers molecular changes in the bilateral striata...
  25. ncbi request reprint gamma-Tocopherol attenuates MPTP-induced dopamine loss more efficiently than alpha-tocopherol in mouse brain
    Nanako Itoh
    Human Stress Signal Research Center, National Institute of Advanced Industrial Science and Technology, AIST, 1 8 31 Midorigaoka Ikeda, Osaka 563 8577, Japan
    Neurosci Lett 403:136-40. 2006
    ..Collectively, this is the first report showing that the protective effect of gammaT is stronger than that of alphaT against the MPTP-induced damage of dopaminergic neurons in the mouse...
  26. ncbi request reprint A prolactin-releasing peptide in the brain
    S Hinuma
    Discovery Research Laboratories I, Pharmaceutical Discovery Research Division, Takeda Chemical Industries Ltd, Tsukuba, Ibaraki, Japan
    Nature 393:272-6. 1998
    ..We show that this ligand is a potent prolactin-releasing factor for rat anterior pituitary cells; we have therefore named this peptide prolactin-releasing peptide...
  27. ncbi request reprint New protein extraction/solubilization protocol for gel-based proteomics of rat (female) whole brain and brain regions
    Misato Hirano
    Human Stress Signal Research Center, National Institute of Advanced Industrial Science and Technology WEST, Ibaraki 305 8569, Japan
    Mol Cells 22:119-25. 2006
    ..Shortcomings apart (failure to separate membrane proteins), gel-based proteomics remains a viable option, and 2-DGE is the method of choice for generating high-resolution proteome maps of rat brain and brain regions...
  28. ncbi request reprint Effects of coffee bean aroma on the rat brain stressed by sleep deprivation: a selected transcript- and 2D gel-based proteome analysis
    Han Seok Seo
    Department of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul 151 742, South Korea
    J Agric Food Chem 56:4665-73. 2008
    ..In conclusion, the roasted coffee bean aroma changes the mRNA and protein expression levels of the rat brain, providing for the first time clues to the potential antioxidant or stress relaxation activities of the coffee bean aroma...
  29. ncbi request reprint Alteration of gene expression of G protein-coupled receptors in endocrine disruptors-caused hyperactive rats
    Masami Ishido
    Endocrine Disruptors and Dioxin Research Projects, National Institute for Environmental Studies, Tsukuba 305 8506, Japan
    Regul Pept 126:145-53. 2005
    ..Thus, endocrine disruptors caused hyperactivity in the rat, probably regulating the levels not only of gene expression but also of proteins of both G-protein-coupled receptors systems and dopaminergic neurotransduction system...
  30. ncbi request reprint p-Nitrotoluene causes hyperactivity in the rat
    Masami Ishido
    Endocrine Disruptors and Dioxin Research Projects, National Institute for Environmental Studies, 16 2 Onogawa, Tsukuba 305 8506, Japan
    Neurosci Lett 366:1-5. 2004
    ..Thus, it was demonstrated for the first time that p-nitrotoluene definitely affected the developing brain, resulting in hyperactivity in the rat...
  31. ncbi request reprint Expression of endothelin-1 and vasoactive intestinal contractor genes in mouse organs during the perinatal period
    Tsuyoshi Uchide
    Department of Toxicology, School of Veterinary Medicine and Animal Sciences, Kitasato University, 35 1, Higashi 23 bancho, Towada, Aomori 034 8628, Japan
    Clin Sci (Lond) 103:167S-170S. 2002
    ....
  32. ncbi request reprint Gel-based proteomics reveals potential novel protein markers of ozone stress in leaves of cultivated bean and maize species of Panama
    Nilka Lineth Torres
    University Regional Center of Azuero, Chitre, Herrera, Republic of Panama
    Electrophoresis 28:4369-81. 2007
    ..Out of these, ten and nine nonredundant proteins in bean and maize, respectively, were identified by MS. A novel pathogenesis-related protein 2 may serve as a potential marker for O(3) stress in bean...