Research Topics
Species | Akiko Miyagi MaeshimaSummaryAffiliation: National Cancer Center Country: Japan Publications
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Detail Information
Publications
Prognostic Impact of Pleural Invasion in 1488 Patients with Surgically Resected Non-small Cell Lung CarcinomaMayumi Oyama
Department of Pathology and Clinical Laboratory, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
Jpn J Clin Oncol 43:540-6. 2013..This study aimed to verify the prognostic impact of pleural invasion according to the revised TNM classification, seventh edition...- Follow-up data of 10 patients with B-cell non-Hodgkin lymphoma with a CD20-negative phenotypic change after rituximab-containing therapyAkiko M Maeshima
Department of Pathology and Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan
Am J Surg Pathol 37:563-70. 2013..As the changes in morphology and CD20 expression after rituximab therapy vary widely, careful follow-up and rebiopsy are recommended... - Bcl-2, Bcl-6, and the International Prognostic Index are prognostic indicators in patients with diffuse large B-cell lymphoma treated with rituximab-containing chemotherapyAkiko Miyagi Maeshima
Department of Pathology and Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan
Cancer Sci 103:1898-904. 2012..In conclusion, Bcl-2 positivity, Bcl-6 negativity, and higher IPI were indicators of shorter PFS and OS plus primary refractory disease in patients with DLBCL in the rituximab era... - Prognostic implication of metastasis limited to segmental (level 13) and/or subsegmental (level 14) lymph nodes in patients with surgically resected nonsmall cell lung carcinoma and pathologic N1 lymph node statusAkiko Miyagi Maeshima
Department of Pathology and Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan
Cancer 118:4512-8. 2012.... - Clinicopathologic analysis of multiple (five or more) atypical adenomatous hyperplasias (AAHs) of the lung: evidence for the AAH-adenocarcinoma sequenceAkiko Miyagi Maeshima
Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan
J Thorac Oncol 5:466-71. 2010..Clarification of the clinicopathologic characteristics of patients with multiple atypical adenomatous hyperplasias (AAHs)... - Histological scoring for small lung adenocarcinomas 2 cm or less in diameter: a reliable prognostic indicatorAkiko Miyagi Maeshima
Clinical Laboratory Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuoku, 104 0045 Tokyo, Japan
J Thorac Oncol 5:333-9. 2010..Lung adenocarcinomas 2 cm or less in diameter were studied to develop histologic criteria predicting the outcome... - Histological and immunophenotypic changes in 59 cases of B-cell non-Hodgkin's lymphoma after rituximab therapyAkiko Miyagi Maeshima
Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan
Cancer Sci 100:54-61. 2009..In conclusion, B-NHL showed various histological and immunophenotypic changes after rituximab therapy, including not only CD20 loss but also proliferation of plasmacytoid cells or transformation to special subtypes of lymphoma... - Histological evaluation of the effect of smoking on peripheral small adenocarcinomas of the lungAkiko Miyagi Maeshima
Clinical Laboratory and double daggerThoracic Surgery Divisions, National Cancer Center Hospital, Tokyo, Japan
J Thorac Oncol 3:698-703. 2008..As there is little information on the histologic characteristics of adenocarcinoma in smokers, we histologically examined the effect of smoking on the carcinogenesis and progression of peripheral small lung adenocarcinomas... - Diffuse large B-cell lymphoma after transformation from low-grade follicular lymphoma: morphological, immunohistochemical, and FISH analysesAkiko Miyagi Maeshima
Clinical Laboratory, National Cancer Center Hospital, Tsukiji 5 1 1, Chuo Ku, Tokyo 104 0045, Japan
Cancer Sci 99:1760-8. 2008..BCL6 translocation was detected in 1/6 (17%) DLBCLs without IGH/BCL2 fusion. Thus, although the morphological features and FISH results for DLBCL were consistent with transformed FL, the immunophenotype showed wide heterogeneity... - Follicular lymphoma of the duodenum: a clinicopathologic analysis of 26 casesKazuhiro Sentani
Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan
Jpn J Clin Oncol 38:547-52. 2008..Follicular lymphomas (FLs) occur commonly in the lymph nodes, and duodenal FL (DFL) is reported to be rare... - Secondary CD5+ diffuse large B-cell lymphoma not associated with transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma (Richter syndrome)Akiko Miyagi Maeshima
Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan
Am J Clin Pathol 131:339-46. 2009..Groups 1 and 2 showed the gain of CD5 during the clinical course or transformation of the tumors, suggesting that CD5 expression is closely associated with the progression of B-cell lymphoma... 
Epidermal growth factor receptor mutation status and clinicopathological features of combined small cell carcinoma with adenocarcinoma of the lungTomoya Fukui
Clinical Laboratory Division, National Cancer Center Hospital, 5 1 1 Tsukuji, Chuo Ku, Tokyo, Japan
Cancer Sci 98:1714-9. 2007..In addition to the clinicopathological characteristics of this rare histological type of lung cancer, these findings provide useful information for better understanding the biology, natural history and clinical management of SCLC...- Comparison of different clones (WT49 versus 6F-H2) of WT-1 antibodies for immunohistochemical diagnosis of malignant pleural mesotheliomaKoji Tsuta
Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan
Appl Immunohistochem Mol Morphol 17:126-30. 2009..Furthermore, the positive reaction of clone WT49 was restricted to nucleus without cytoplasmic staining, which is seen in conventionally used WT-1 antibodies... - Malignant pulmonary epithelioid hemangioendothelioma with hilar lymph node metastasisNaobumi Tochigi
Pathology Division, National Cancer Center Research Institute, Tokyo 104 0045, Japan
Ann Diagn Pathol 15:207-12. 2011.... - Modified cyclophosphamide, vincristine, doxorubicin, and methotrexate (CODOX-M)/ifosfamide, etoposide, and cytarabine (IVAC) therapy with or without rituximab in Japanese adult patients with Burkitt lymphoma (BL) and B cell lymphoma, unclassifiable, with Dai Maruyama
Hematology Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
Int J Hematol 92:732-43. 2010..In conclusion, our modified CODOX-M/IVAC regimen is well tolerated and highly effective in Japanese adult patients with BL and intermediate DLBCL/BL, warranting a larger study for confirmation... - Carcinoma of donor origin after allogeneic peripheral blood stem cell transplantationWataru Munakata
Departments of Hematology and Hematopoietic Stem Cell Transplantation, Division of Thoracic Surgery, National Cancer Center Hospital, Chuo Ku, Tokyo, Japan
Am J Surg Pathol 36:1376-84. 2012..Our observations suggest that transfused peripheral blood cells may be involved in the development of cancers after allogeneic peripheral blood stem cell transplantation... - Primary ocular adnexal MALT lymphoma: a long-term follow-up study of 114 patientsKazuki Tanimoto
Hematology and Stem Cell Transplantation Division, National Cancer Center Hospital and Research Institute, Tokyo, Japan
Jpn J Clin Oncol 37:337-44. 2007.... 
Fluorescence in situ hybridization (FISH) analysis of primary ocular adnexal MALT lymphomaKazuki Tanimoto
Hematology and Stem Cell Transplantation Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
BMC Cancer 6:249. 2006....- Follicular lymphoma with marked monocytoid or plasmacytoid differentiation and tiny or indistinct follicles: a case study of four patientsKenji Yamada
Pathology Division, National Cancer Center Hospital, Tokyo, Japan
Leuk Lymphoma 52:804-13. 2011..Identifying tiny CD10+/BCL-2+ neoplastic follicles, detecting IGH/BCL2 fusion by FISH, and considering a history of FL are crucial for diagnosing such exceptional cases of FL... - Analysis of expression patterns of breast cancer-specific markers (mammaglobin and gross cystic disease fluid protein 15) in lung and pleural tumorsYuji Takeda
Clinical Laboratory Department, National Cancer Center Hospital, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo 104 0045, Japan
Arch Pathol Lab Med 132:239-43. 2008..Although it is often difficult to make a clear-cut differential diagnosis between the two, distinguishing primary lung carcinoma from breast carcinoma metastatic to the lung is important because the treatment modalities are different... - Cytological features of signet-ring cell carcinoma of the lung: comparison with the goblet-cell-type adenocarcinoma of the lungKoji Tsuta
Division of Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan
Diagn Cytopathol 37:159-63. 2009..The cytological features of SRCC were the presence of single tumor cells and nuclear pleomorphism, whereas that of GCA were the presence of abundant mucin and significant inflammation in the background, and a honeycomb-like cluster... - Diffuse large B-cell lymphoma with extra Bcl-2 gene signals detected by FISH analysis is associated with a "non-germinal center phenotype"Shigeru Kusumoto
Hematology Division, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan
Am J Surg Pathol 29:1067-73. 2005..The DLBCLs with Bcl-2 protein overexpression were classified into at least two heterogeneous molecular groups, based on the results of the FISH analysis... - Immunohistochemical detection of GLUT-1 can discriminate between reactive mesothelium and malignant mesotheliomaYasufumi Kato
Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan
Mod Pathol 20:215-20. 2007..On the other hand, no RM cases were positive for GLUT-1. GLUT-1 is a sensitive and specific immunohistochemical marker enabling differential diagnosis of RM from MPM, whereas it cannot discriminate MPM from lung carcinoma... - Deletion of the TNFAIP3/A20 gene detected by FICTION analysis in classical Hodgkin lymphomaJunko Nomoto
Hematology Division, National Cancer Center Hospital, Tokyo, Japan
BMC Cancer 12:457. 2012..However, the detection of this in primary Hodgkin lymphoma (HL) specimens is hampered by the scarcity of Hodgkin Reed-Sternberg (HR-S) cells even after enrichment by micro-dissection... - Histologic prognostic factors for small-sized squamous cell carcinomas of the peripheral lungAkiko Miyagi Maeshima
Pathology Division, National Cancer Center Research Institute, Tokyo, Japan
Lung Cancer 52:53-8. 2006..Tumors with a single cell invasive component appear to be highly malignant, and should be distinguished from invasive cancers with a low malignant potential (tumors with large or small tumor nest components)... - Clinicopathological analysis of primary lung carcinoma with heterotopic ossificationHidehiko Kuribayashi
Clinical Laboratory Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
Lung Cancer 64:160-5. 2009..The present study suggested that IHO associated with adenocarcinomas and BMP-2 production in the tumor cells, whereas EHO was not associated with the biology of the carcinoma... - Detection of EGFR mutations in archived cytologic specimens of non-small cell lung cancer using high-resolution melting analysisKiyoaki Nomoto
Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan
Am J Clin Pathol 126:608-15. 2006..The sensitivity of this analysis was 90% (19/21) and specificity, 100% (15/15). These results suggest that HRMA of archived cytologic specimens of advanced NSCLC is useful for detecting EGFR mutations in clinical practice... - Two entities of precursor T-cell lymphoblastic leukemia/lymphoma based on radiologic and immunophenotypic findingsYasushi Onishi
Hematology Division, National Cancer Center Hospital, Tsukiji, Chou-ku, Tokyo, Japan
Int J Hematol 80:43-51. 2004..This study was performed in a single institution, was retrospective, and had a limited number of patients; multicenter confirmatory studies are warranted... - Comparison of outcomes after allogeneic hematopoietic stem cell transplantation in patients with follicular lymphoma, diffuse large B-cell lymphoma associated with follicular lymphoma, or de novo diffuse large B-cell lymphomaKohei Tada
Department of Hematology and Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan
Am J Hematol 87:770-5. 2012..These results suggest that allo-HCT may be a promising option for patients with not only advanced FL but also DLBCL associated with FL...