Hideo Kurebayashi

Summary

Affiliation: National Institute of Health Sciences
Country: Japan

Publications

  1. ncbi request reprint Disposition of a low dose of bisphenol a in male and female cynomolgus monkeys
    Hideo Kurebayashi
    Division of Pharmacology, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya, Tokyo 158 8501, Japan
    Toxicol Sci 68:32-42. 2002
  2. ncbi request reprint Metabolism and excretion of 2-nitro-p-cresol in rats
    Hideo Kurebayashi
    National Institute of Health Sciences, 1 18 1, Kamiyoga, Setagaya, Tokyo 158 8501, Japan
    Arch Toxicol 76:676-81. 2002
  3. ncbi request reprint Disposition of a low dose of 14C-bisphenol A in male rats and its main biliary excretion as BPA glucuronide
    Hideo Kurebayashi
    Division of Pharmacology, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya, Tokyo 158 8501, Japan
    Toxicol Sci 73:17-25. 2003
  4. ncbi request reprint Disposition of low doses of 14C-bisphenol A in male, female, pregnant, fetal, and neonatal rats
    Hideo Kurebayashi
    Division of Pharmacology, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya, 158 8501 Tokyo, Japan
    Arch Toxicol 79:243-52. 2005
  5. ncbi request reprint Metabolism of acrylamide to glycidamide and their cytotoxicity in isolated rat hepatocytes: protective effects of GSH precursors
    Hideo Kurebayashi
    Division of Pharmacology, Biological Safety Research Center, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya, Tokyo 158 8501, Japan
    Arch Toxicol 80:820-8. 2006
  6. doi request reprint Species difference of metabolic clearance of bisphenol A using cryopreserved hepatocytes from rats, monkeys and humans
    Hideo Kurebayashi
    Division of Pharmacology, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya Ku, Tokyo 158 8501, Japan
    Toxicol Lett 198:210-5. 2010

Detail Information

Publications6

  1. ncbi request reprint Disposition of a low dose of bisphenol a in male and female cynomolgus monkeys
    Hideo Kurebayashi
    Division of Pharmacology, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya, Tokyo 158 8501, Japan
    Toxicol Sci 68:32-42. 2002
    ..5%) after oral dose. These results indicate that the intestinal absorption and metabolism of BPA was rapid and extensive, and the major metabolites, glucuronide conjugates of 14C-BPA, were rapidly excreted into urine in monkeys...
  2. ncbi request reprint Metabolism and excretion of 2-nitro-p-cresol in rats
    Hideo Kurebayashi
    National Institute of Health Sciences, 1 18 1, Kamiyoga, Setagaya, Tokyo 158 8501, Japan
    Arch Toxicol 76:676-81. 2002
    ..NPC was rapidly absorbed and excreted mainly into urine as the conjugate metabolites. A part of NPC was reduced to 2-amino- p-cresol, followed by acetylation to give AAPC...
  3. ncbi request reprint Disposition of a low dose of 14C-bisphenol A in male rats and its main biliary excretion as BPA glucuronide
    Hideo Kurebayashi
    Division of Pharmacology, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya, Tokyo 158 8501, Japan
    Toxicol Sci 73:17-25. 2003
    ..These results suggest that BPA is mainly metabolized to BPA-gluc and excreted into feces through the bile and subject to enterohepatic circulation in rats irrespective of dose and administration route...
  4. ncbi request reprint Disposition of low doses of 14C-bisphenol A in male, female, pregnant, fetal, and neonatal rats
    Hideo Kurebayashi
    Division of Pharmacology, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya, 158 8501 Tokyo, Japan
    Arch Toxicol 79:243-52. 2005
    ..Part of radioactivity was transferred to neonatal rats from the milk of the treated lactating dam and remained in the intestine of the neonates after 24-h nursing by an untreated dam...
  5. ncbi request reprint Metabolism of acrylamide to glycidamide and their cytotoxicity in isolated rat hepatocytes: protective effects of GSH precursors
    Hideo Kurebayashi
    Division of Pharmacology, Biological Safety Research Center, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya, Tokyo 158 8501, Japan
    Arch Toxicol 80:820-8. 2006
    ..GSH precursors such as N-acetylcysteine and methionine provided significant anti-cytotoxic effects on the decrease of GSH content and cell viability of hepatocytes induced by GA and AA...
  6. doi request reprint Species difference of metabolic clearance of bisphenol A using cryopreserved hepatocytes from rats, monkeys and humans
    Hideo Kurebayashi
    Division of Pharmacology, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya Ku, Tokyo 158 8501, Japan
    Toxicol Lett 198:210-5. 2010
    ..27), correlating well with in vivo studies of BPA subcutaneously injected rats and monkeys. This study showed that the cryopreserved hepatocytes could be a useful tool for assessing BPA metabolism and predicting systemic exposure of BPA...