Sachiko Koike

Summary

Affiliation: National Institute of Radiological Sciences
Country: Japan

Publications

  1. ncbi Relative biological effectiveness of 290 MeV/u carbon ions for the growth delay of a radioresistant murine fibrosarcoma
    Sachiko Koike
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba 263 5555, Japan
    J Radiat Res 43:247-55. 2002
  2. ncbi Repair of skin damage during fractionated irradiation with gamma rays and low-LET carbon ions
    Koichi Ando
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 47:167-74. 2006
  3. ncbi [11C]Gefitinib ([11c]Iressa): radiosynthesis, in vitro uptake, and in vivo imaging of intact murine fibrosarcoma
    Ming Rong Zhang
    Department of Molecular Probes, Molecular Imaging Center, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba, Japan
    Mol Imaging Biol 12:181-91. 2010
  4. ncbi Comparison of biological effectiveness of carbon-ion beams in Japan and Germany
    Akiko Uzawa
    Heavy Ion Radiobiology Research Group, Research Center of Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan
    Int J Radiat Oncol Biol Phys 73:1545-51. 2009
  5. ncbi Imaging of peripheral-type benzodiazepine receptor in tumor: carbon ion irradiation reduced the uptake of a positron emission tomography ligand [11C]DAC in tumor
    Tomoteru Yamasaki
    Department of Molecular Probes, Molecular Imaging Centre, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 51:57-65. 2010
  6. ncbi Biological gain of carbon-ion radiotherapy for the early response of tumor growth delay and against early response of skin reaction in mice
    Koichi Ando
    Heavy Ion Radiology Research Group, National Institute of Radiological Sciences, Chiba shi, Chiba, Japan
    J Radiat Res 46:51-7. 2005
  7. ncbi Tumor induction in mice locally irradiated with carbon ions: a retrospective analysis
    Koichi Ando
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 46:185-90. 2005
  8. ncbi Early growth of experimental lung metastasis in mouse
    Koichi Ando
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 46:289-92. 2005
  9. ncbi Changes in the pharmacokinetics of Gd-DTPA in experimental tumors after charged particle radiation: comparison with gamma-ray radiation
    Takayuki Obata
    Department of Medical Imaging, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 45:261-7. 2004
  10. ncbi Differences in pO2 peaks of a murine fibrosarcoma between carbon-ion and X-ray irradiation
    Takeshi Fukawa
    Institute of Biomedical Engineering, Keio University, Yokohama, Japan
    J Radiat Res 45:303-8. 2004

Collaborators

Detail Information

Publications17

  1. ncbi Relative biological effectiveness of 290 MeV/u carbon ions for the growth delay of a radioresistant murine fibrosarcoma
    Sachiko Koike
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba 263 5555, Japan
    J Radiat Res 43:247-55. 2002
    ..These results together with our earlier study on the skin reaction support the use of an RBE of 3.0 in clinical trials of 80 keV/microm carbon beams. The RBE values for low doses of carbon beams were also considered...
  2. ncbi Repair of skin damage during fractionated irradiation with gamma rays and low-LET carbon ions
    Koichi Ando
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 47:167-74. 2006
    ....
  3. ncbi [11C]Gefitinib ([11c]Iressa): radiosynthesis, in vitro uptake, and in vivo imaging of intact murine fibrosarcoma
    Ming Rong Zhang
    Department of Molecular Probes, Molecular Imaging Center, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba, Japan
    Mol Imaging Biol 12:181-91. 2010
    ..In this study, we labeled gefitinib with carbon-11 and evaluated [(11)C]gefitinib to explore its specific binding in intact fibrosarcoma (NFSa)-bearing mice...
  4. ncbi Comparison of biological effectiveness of carbon-ion beams in Japan and Germany
    Akiko Uzawa
    Heavy Ion Radiobiology Research Group, Research Center of Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan
    Int J Radiat Oncol Biol Phys 73:1545-51. 2009
    ..To compare the biological effectiveness of 290 MeV/amu carbon-ion beams in Chiba, Japan and in Darmstadt, Germany, given that different methods for beam delivery are used for each...
  5. ncbi Imaging of peripheral-type benzodiazepine receptor in tumor: carbon ion irradiation reduced the uptake of a positron emission tomography ligand [11C]DAC in tumor
    Tomoteru Yamasaki
    Department of Molecular Probes, Molecular Imaging Centre, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 51:57-65. 2010
    ..In conclusion, [(11)C]DAC PET responded to the change in PBR expression in tumors caused by carbon ion irradiation in this study. Thus, [(11)C]DAC is a promising predictor for evaluating the effect of carbon ion radiotherapy...
  6. ncbi Biological gain of carbon-ion radiotherapy for the early response of tumor growth delay and against early response of skin reaction in mice
    Koichi Ando
    Heavy Ion Radiology Research Group, National Institute of Radiological Sciences, Chiba shi, Chiba, Japan
    J Radiat Res 46:51-7. 2005
    ..These data provide evidence that high-LET radiotherapy could achieve therapeutic gain by minimizing the difference in response to fractionated irradiation between the tumor and normal tissue...
  7. ncbi Tumor induction in mice locally irradiated with carbon ions: a retrospective analysis
    Koichi Ando
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 46:185-90. 2005
    ..2 for tumor induction and 1.9 for early skin reaction. We conclude that risk of secondary tumor induction by carbon-ion radiotherapy would not be seriously higher than anticipated...
  8. ncbi Early growth of experimental lung metastasis in mouse
    Koichi Ando
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 46:289-92. 2005
    ..3 and 13.1 hr were obtained by use of the survival ratio and of the extrapolation number, respectively. This method is useful to measure the growth dynamics of clonogenic tumor cells at the site of a metastasized organ...
  9. ncbi Changes in the pharmacokinetics of Gd-DTPA in experimental tumors after charged particle radiation: comparison with gamma-ray radiation
    Takayuki Obata
    Department of Medical Imaging, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 45:261-7. 2004
    ..Tmax and Td in the carbon-ion irradiated tumors were different from those in the gamma-ray-irradiated tumors. These treatment-specific kinetics may be useful in predicting the therapeutic efficacy of carbon-ion treatment...
  10. ncbi Differences in pO2 peaks of a murine fibrosarcoma between carbon-ion and X-ray irradiation
    Takeshi Fukawa
    Institute of Biomedical Engineering, Keio University, Yokohama, Japan
    J Radiat Res 45:303-8. 2004
    ..It is concluded that carbon-ion irradiation reoxygenated the NFSa fibrosarcomas earlier in time and deeper in space than the X-ray irradiation did...
  11. ncbi Effects of beer administration in mice on acute toxicities induced by X rays and carbon ions
    Manami Monobe
    Graduate School of Science and Technology, Chiba University, 1 33, Yayoi cho, Inage Ku, Chiba 263 8522, Japan
    J Radiat Res 44:75-80. 2003
    ..Radioprotection by beer administration is not solely due to OH radical-scavenging action by the ethanol contained in beer...
  12. ncbi Imaging of peripheral-type benzodiazepine receptor in tumor: in vitro binding and in vivo biodistribution of N-benzyl-N-[(11)C]methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide
    Tomoteru Yamasaki
    Department of Molecular Probes, Molecular Imaging Center, National Institute of Radiological Sciences, Chiba 263 8555, Japan
    Nucl Med Biol 36:801-9. 2009
    ..The aim of this study was to evaluate N-benzyl-N-[(11)C]methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([(11)C]DAC) as a novel peripheral-type benzodiazepine receptor (PBR) ligand for tumor imaging...
  13. ncbi Radioprotective activities of beer administration for radiation-induced acute toxicity in mice
    Manami Monobe
    Graduate School of Science Technology, Chiba University, Japan
    Radiother Oncol 73:S127-9. 2004
    ..The DRF (D10) of beer- and ethanol-administered mice for carbon ions was 1.08 and 1.07, respectively. CONCLUSIONS: The radioprotection by beer-administration is due to not only OH radical-scavenge action by the ethanol contained in beer...
  14. ncbi Radiobiologic significance of response of intratumor quiescent cells in vivo to accelerated carbon ion beams compared with gamma-rays and reactor neutron beams
    Shin Ichiro Masunaga
    Particle Radiation Oncology Research Center, Research Reactor Institute, Kyoto University, Kumatori, Osaka, Japan
    Int J Radiat Oncol Biol Phys 70:221-8. 2008
    ..To clarify the radiosensitivity of intratumor quiescent cells in vivo to accelerated carbon ion beams and reactor neutron beams...
  15. ncbi The radiosensitivity of total and quiescent cell populations in solid tumors to 290 MeV/u carbon ion beam irradiation in vivo
    Shin Ichiro Masunaga
    Particle Radiation Oncology Research Center, Research Reactor Institute, Kyoto University, Kumatori cho, Osaka, Sennan gun, Japan
    Acta Oncol 47:1087-93. 2008
    ..To clarify the radiosensitivity of intratumor total and quiescent (Q) cells in vivo to accelerated carbon ion beams compared with gamma-ray irradiation...
  16. ncbi Responses of total and quiescent cell populations in solid tumors to carbon ion beam irradiation (290 MeV/u) in vivo
    Shin Ichiro Masunaga
    Particle Radiation Oncology Research Center, Research Reactor Institute, Kyoto University, Sennan, Osaka, Japan
    Radiat Med 26:270-7. 2008
    ..The aim of this study was to clarify the radiosensitivity of intratumor total cells and quiescent (Q) cells in vivo to accelerated carbon ion beams compared with gamma-ray irradiation...
  17. ncbi Enhancement of the relative uptake of 18F-FDG in mouse fibrosarcoma by rolipram
    Kaoru Kobayashi
    Department of Medical Physics, School of Allied Health Science Faculty of Medicine, Osaka University, Suita Shi, Japan
    Ann Nucl Med 16:507-10. 2002
    ..9 to 6.5 by rolipram. This indicates the possible use of rolipram to enhance the sensitivity of tumor detection, as well as characterization of tumors in 18F-FDG PET...