Sachiko Koike

Summary

Affiliation: National Institute of Radiological Sciences
Country: Japan

Publications

  1. ncbi request reprint Relative biological effectiveness of 290 MeV/u carbon ions for the growth delay of a radioresistant murine fibrosarcoma
    Sachiko Koike
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba 263 5555, Japan
    J Radiat Res 43:247-55. 2002
  2. ncbi request reprint Repair of skin damage during fractionated irradiation with gamma rays and low-LET carbon ions
    Koichi Ando
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 47:167-74. 2006
  3. doi request reprint Comparison of biological effectiveness of carbon-ion beams in Japan and Germany
    Akiko Uzawa
    Heavy Ion Radiobiology Research Group, Research Center of Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan
    Int J Radiat Oncol Biol Phys 73:1545-51. 2009
  4. doi request reprint [11C]Gefitinib ([11c]Iressa): radiosynthesis, in vitro uptake, and in vivo imaging of intact murine fibrosarcoma
    Ming Rong Zhang
    Department of Molecular Probes, Molecular Imaging Center, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba, Japan
    Mol Imaging Biol 12:181-91. 2010
  5. ncbi request reprint Imaging of peripheral-type benzodiazepine receptor in tumor: carbon ion irradiation reduced the uptake of a positron emission tomography ligand [11C]DAC in tumor
    Tomoteru Yamasaki
    Department of Molecular Probes, Molecular Imaging Centre, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 51:57-65. 2010
  6. ncbi request reprint Biological gain of carbon-ion radiotherapy for the early response of tumor growth delay and against early response of skin reaction in mice
    Koichi Ando
    Heavy Ion Radiology Research Group, National Institute of Radiological Sciences, Chiba shi, Chiba, Japan
    J Radiat Res 46:51-7. 2005
  7. ncbi request reprint Tumor induction in mice locally irradiated with carbon ions: a retrospective analysis
    Koichi Ando
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 46:185-90. 2005
  8. doi request reprint Evaluation of SCCVII tumor cell survival in clamped and non-clamped solid tumors exposed to carbon-ion beams in comparison to X-rays
    Ryoichi Hirayama
    Next Generation Medical Physics Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Japan Heavy Ion Radiobiology Research Group, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Japan Electronic address
    Mutat Res 756:146-51. 2013
  9. doi request reprint Fractionated irradiation of carbon beam and the isoeffect dose on acute reaction of skin
    Akiko Uzawa
    National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba shi, Chiba 263 8555, Japan
    J Radiat Res 55:i135-i136. 2014
  10. ncbi request reprint Early growth of experimental lung metastasis in mouse
    Koichi Ando
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 46:289-92. 2005

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Relative biological effectiveness of 290 MeV/u carbon ions for the growth delay of a radioresistant murine fibrosarcoma
    Sachiko Koike
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba 263 5555, Japan
    J Radiat Res 43:247-55. 2002
    ..These results together with our earlier study on the skin reaction support the use of an RBE of 3.0 in clinical trials of 80 keV/microm carbon beams. The RBE values for low doses of carbon beams were also considered...
  2. ncbi request reprint Repair of skin damage during fractionated irradiation with gamma rays and low-LET carbon ions
    Koichi Ando
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 47:167-74. 2006
    ....
  3. doi request reprint Comparison of biological effectiveness of carbon-ion beams in Japan and Germany
    Akiko Uzawa
    Heavy Ion Radiobiology Research Group, Research Center of Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan
    Int J Radiat Oncol Biol Phys 73:1545-51. 2009
    ..To compare the biological effectiveness of 290 MeV/amu carbon-ion beams in Chiba, Japan and in Darmstadt, Germany, given that different methods for beam delivery are used for each...
  4. doi request reprint [11C]Gefitinib ([11c]Iressa): radiosynthesis, in vitro uptake, and in vivo imaging of intact murine fibrosarcoma
    Ming Rong Zhang
    Department of Molecular Probes, Molecular Imaging Center, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba, Japan
    Mol Imaging Biol 12:181-91. 2010
    ..In this study, we labeled gefitinib with carbon-11 and evaluated [(11)C]gefitinib to explore its specific binding in intact fibrosarcoma (NFSa)-bearing mice...
  5. ncbi request reprint Imaging of peripheral-type benzodiazepine receptor in tumor: carbon ion irradiation reduced the uptake of a positron emission tomography ligand [11C]DAC in tumor
    Tomoteru Yamasaki
    Department of Molecular Probes, Molecular Imaging Centre, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 51:57-65. 2010
    ..In conclusion, [(11)C]DAC PET responded to the change in PBR expression in tumors caused by carbon ion irradiation in this study. Thus, [(11)C]DAC is a promising predictor for evaluating the effect of carbon ion radiotherapy...
  6. ncbi request reprint Biological gain of carbon-ion radiotherapy for the early response of tumor growth delay and against early response of skin reaction in mice
    Koichi Ando
    Heavy Ion Radiology Research Group, National Institute of Radiological Sciences, Chiba shi, Chiba, Japan
    J Radiat Res 46:51-7. 2005
    ..These data provide evidence that high-LET radiotherapy could achieve therapeutic gain by minimizing the difference in response to fractionated irradiation between the tumor and normal tissue...
  7. ncbi request reprint Tumor induction in mice locally irradiated with carbon ions: a retrospective analysis
    Koichi Ando
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 46:185-90. 2005
    ..2 for tumor induction and 1.9 for early skin reaction. We conclude that risk of secondary tumor induction by carbon-ion radiotherapy would not be seriously higher than anticipated...
  8. doi request reprint Evaluation of SCCVII tumor cell survival in clamped and non-clamped solid tumors exposed to carbon-ion beams in comparison to X-rays
    Ryoichi Hirayama
    Next Generation Medical Physics Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Japan Heavy Ion Radiobiology Research Group, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Japan Electronic address
    Mutat Res 756:146-51. 2013
    ..To conclude, we found that the RBE values for cell survival increased with increasing LET and that the OER values changed little with increasing LET within the SOBP carbon-ion beams. ..
  9. doi request reprint Fractionated irradiation of carbon beam and the isoeffect dose on acute reaction of skin
    Akiko Uzawa
    National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba shi, Chiba 263 8555, Japan
    J Radiat Res 55:i135-i136. 2014
    ..Clinical Trial Registration number if required: No. Fig. 1.The reciprocal of the isoeffect dose is plotted against the dose per fraction. (i) Gamma ray: Fe-plot was linear. (ii) C-ions: Fe-plot bent at low fractions. ..
  10. ncbi request reprint Early growth of experimental lung metastasis in mouse
    Koichi Ando
    Heavy Ion Radiobiology Research Group, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 46:289-92. 2005
    ..3 and 13.1 hr were obtained by use of the survival ratio and of the extrapolation number, respectively. This method is useful to measure the growth dynamics of clonogenic tumor cells at the site of a metastasized organ...
  11. ncbi request reprint Changes in the pharmacokinetics of Gd-DTPA in experimental tumors after charged particle radiation: comparison with gamma-ray radiation
    Takayuki Obata
    Department of Medical Imaging, National Institute of Radiological Sciences, Chiba, Japan
    J Radiat Res 45:261-7. 2004
    ..Tmax and Td in the carbon-ion irradiated tumors were different from those in the gamma-ray-irradiated tumors. These treatment-specific kinetics may be useful in predicting the therapeutic efficacy of carbon-ion treatment...
  12. doi request reprint Quantitative 17O imaging towards oxygen consumption study in tumor bearing mice at 7 T
    Michiko Narazaki
    Molecular Imaging Research Center, National Institute of Radiological Sciences, Chiba, Japan
    Magn Reson Imaging 31:643-50. 2013
    ..Experiments using various model compounds of R-OH type clarified that the signal contribution of body constituents other than water in the present in vivo(17)O FISP image was negligible...
  13. ncbi request reprint Differences in pO2 peaks of a murine fibrosarcoma between carbon-ion and X-ray irradiation
    Takeshi Fukawa
    Institute of Biomedical Engineering, Keio University, Yokohama, Japan
    J Radiat Res 45:303-8. 2004
    ..It is concluded that carbon-ion irradiation reoxygenated the NFSa fibrosarcomas earlier in time and deeper in space than the X-ray irradiation did...
  14. ncbi request reprint Effects of beer administration in mice on acute toxicities induced by X rays and carbon ions
    Manami Monobe
    Graduate School of Science and Technology, Chiba University, 1 33, Yayoi cho, Inage Ku, Chiba 263 8522, Japan
    J Radiat Res 44:75-80. 2003
    ..Radioprotection by beer administration is not solely due to OH radical-scavenging action by the ethanol contained in beer...
  15. doi request reprint Imaging of peripheral-type benzodiazepine receptor in tumor: in vitro binding and in vivo biodistribution of N-benzyl-N-[(11)C]methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide
    Tomoteru Yamasaki
    Department of Molecular Probes, Molecular Imaging Center, National Institute of Radiological Sciences, Chiba 263 8555, Japan
    Nucl Med Biol 36:801-9. 2009
    ..The aim of this study was to evaluate N-benzyl-N-[(11)C]methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([(11)C]DAC) as a novel peripheral-type benzodiazepine receptor (PBR) ligand for tumor imaging...
  16. doi request reprint Responses of total and quiescent cell populations in solid tumors to carbon ion beam irradiation (290 MeV/u) in vivo
    Shin Ichiro Masunaga
    Particle Radiation Oncology Research Center, Research Reactor Institute, Kyoto University, Sennan, Osaka, Japan
    Radiat Med 26:270-7. 2008
    ..The aim of this study was to clarify the radiosensitivity of intratumor total cells and quiescent (Q) cells in vivo to accelerated carbon ion beams compared with gamma-ray irradiation...
  17. doi request reprint The radiosensitivity of total and quiescent cell populations in solid tumors to 290 MeV/u carbon ion beam irradiation in vivo
    Shin Ichiro Masunaga
    Particle Radiation Oncology Research Center, Research Reactor Institute, Kyoto University, Kumatori cho, Osaka, Sennan gun, Japan
    Acta Oncol 47:1087-93. 2008
    ..To clarify the radiosensitivity of intratumor total and quiescent (Q) cells in vivo to accelerated carbon ion beams compared with gamma-ray irradiation...
  18. ncbi request reprint Radiobiologic significance of response of intratumor quiescent cells in vivo to accelerated carbon ion beams compared with gamma-rays and reactor neutron beams
    Shin Ichiro Masunaga
    Particle Radiation Oncology Research Center, Research Reactor Institute, Kyoto University, Kumatori, Osaka, Japan
    Int J Radiat Oncol Biol Phys 70:221-8. 2008
    ..To clarify the radiosensitivity of intratumor quiescent cells in vivo to accelerated carbon ion beams and reactor neutron beams...
  19. ncbi request reprint Radioprotective activities of beer administration for radiation-induced acute toxicity in mice
    Manami Monobe
    Graduate School of Science Technology, Chiba University, Japan
    Radiother Oncol 73:S127-9. 2004
    ..In this study, we investigated the radioprotective activities of beer-administration for bone marrow and intestine in mice...
  20. ncbi request reprint Enhancement of the relative uptake of 18F-FDG in mouse fibrosarcoma by rolipram
    Kaoru Kobayashi
    Department of Medical Physics, School of Allied Health Science Faculty of Medicine, Osaka University, Suita Shi, Japan
    Ann Nucl Med 16:507-10. 2002
    ..9 to 6.5 by rolipram. This indicates the possible use of rolipram to enhance the sensitivity of tumor detection, as well as characterization of tumors in 18F-FDG PET...