Research Topics
| S KitamuraSummaryAffiliation: National Cardiovascular Center Country: Japan Publications
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Publications
Heart transplantation in Japan: a critical appraisal for the results and future prospectsSoichiro Kitamura
Cardiovascular and Transplant Surgery, National Cerebral and Cardiovascular Center, 5 7 1 Fujishirodai, Suita, Osaka, 565 8565, Japan
Gen Thorac Cardiovasc Surg 60:639-44. 2012....
Modification of bicaval anastomosis technique for orthotopic heart transplantationS Kitamura
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Ann Thorac Surg 72:1405-6. 2001....
The role of coronary bypass operation on children with Kawasaki diseaseSoichiro Kitamura
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Coron Artery Dis 13:437-47. 2002..Development of surgical treatment for the disease was essential in preventing premature death and improving the quality of life of children...
Hemodynamic and echocardiographic evaluation of orthotopic heart transplantation with the modified bicaval anastomosis techniqueSoichiro Kitamura
Department of Organ Transplantation, Cardiovascular Surgery, National Cardiovascular Center, Suita, Japan
Circ J 73:1235-9. 2009..The purpose of this study was to evaluate the hemodynamic and echocardiographic function of hearts transplanted with the modified bicaval anastomosis technique (mBCAT)...
Twenty-five-year outcome of pediatric coronary artery bypass surgery for Kawasaki diseaseSoichiro Kitamura
Department of Cardiovascular Surgery, National Cardiovascular Center, 5 7 1 Fujishirodai, Suita, Osaka 565 8565, Japan
Circulation 120:60-8. 2009..The long-term outcome of pediatric coronary artery bypass for patients with severe inflammatory coronary sequelae secondary to Kawasaki disease is unknown...
Physiological and metabolic effects of grafts in coronary artery bypass surgerySoichiro Kitamura
National Cerebral and Cardiovascular Center, 5 7 1 Fujishirodai, Suita, Osaka 565 8565, Japan
Circ J 75:766-72. 2011..The production of nitric oxide and prostanoids by the ITA endothelium and their beneficial effects on the downstream coronary artery should therefore be taken into consideration when debating the merits of CABG vs. PCI...
Is distal anastomosis only to the true channel in chronic type B aortic dissection justified?Y Okita
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Ann Thorac Surg 68:1586-91. 1999..We investigated long-term outcomes of the distal false lumen of the aorta and aortic branches after distal anastomosis of the graft only to the true lumen in chronic type B aortic dissection...
Ten-year experience of chordal replacement with expanded polytetrafluoroethylene in mitral valve repairJ Kobayashi
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Circulation 102:III30-4. 2000....
Early and long-term results of surgery for aneurysms of the thoracic aorta in septuagenarians and octogenariansY Okita
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Eur J Cardiothorac Surg 16:317-23. 1999....
Eight-year experience of combined valve repair for mitral regurgitation and maze procedureJunjiro Kobayashi
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
J Heart Valve Dis 11:165-71; discussion 171-2. 2002..Postoperative sinus rhythm conversion by the maze procedure may reduce left ventricular size, and the incidence of thromboembolic episodes in mitral valve repair...
Limitations of EuroSCORE for measurement of risk-stratified mortality in aortic arch surgery using selective cerebral perfusion: is advanced age no longer a risk?Kaoru Matsuura
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Ann Thorac Surg 81:2084-7. 2006..The aim of this study was to examine the usefulness of the EuroSCORE, and our modification of it regarding age, in predicting mortality after aortic arch repair performed with selective cerebral perfusion...
Induction of heparin binding epidermal growth factor-like growth factor and amphiregulin mRNAs by gastrin in the rat stomachS Tsutsui
Second Department of Internal Medicine, Osaka University Medical School, Suita, Japan
Biochem Biophys Res Commun 235:520-3. 1997..These findings indicate that heparin-binding epidermal growth factor-like growth factor and amphiregulin genes are induced by gastrin and that they play a role in the trophic action of gastrin on oxyntic mucosa...
Evolving selective cerebral perfusion for aortic arch replacement: high flow rate with moderate hypothermic circulatory arrestKenji Minatoya
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Ann Thorac Surg 86:1827-31. 2008..We have since 2002 gradually elevated the temperature of HCA from 20 degrees C to 28 degrees C for aortic arch surgery. This study explored the impact of different temperatures during HCA with SCP on neurologic complications...
Total arch replacement using antegrade selective cerebral perfusion with right axillary artery perfusionSatoshi Numata
Department of Cardiovascular Surgery, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan
Eur J Cardiothorac Surg 23:771-5; discussion 775. 2003....
Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarctionYoshinori Miyahara
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center Research Institute, Suita, Osaka, Japan
Nat Med 12:459-65. 2006..Thus, transplantation of monolayered mesenchymal stem cells may be a new therapeutic strategy for cardiac tissue regeneration...
A morphologic study of Carpentier-Edwards pericardial xenografts in the mitral position exhibiting primary tissue failure in adults in comparison with Ionescu-Shiley pericardial xenograftsH Machida
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
J Thorac Cardiovasc Surg 122:649-55. 2001..We sought to investigate the durability and mechanism of the Carpentier-Edwards pericardial xenograft in the mitral position in comparison with that of the Ionescu-Shiley pericardial xenograft...
Total cavopulmonary connection in children with body weight less than 10 kgH Uemura
Department of Cardiovascular Surgery, National Cardiovascular Center, 5 7 1 Fujishirodai, Suita, Osaka, Japan
Eur J Cardiothorac Surg 17:543-9. 2000..To evaluate the results after total cavopulmonary connection (TCPC) in small children, our clinical experience was retrospectively reviewed...
Maze procedure for atrial fibrillation associated with atrial septal defectJ Kobayashi
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Circulation 98:II399-402. 1998..However, use of the simultaneous maze procedure for AF associated with ASD remains controversial. We examined the efficacy and risk of the use of the maze procedure in these patients...
Hemolytic anemia after operation for aortic dissection using teflon felt stripsYuki Nakamura
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Ann Thorac Surg 85:1784-7. 2008..As a precaution, it is necessary to be meticulous when stitching the internal felt strip...
Bone marrow mononuclear cell transplantation had beneficial effects on doxorubicin-induced cardiomyopathyMichiko Ishida
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center, Osaka, Japan
J Heart Lung Transplant 23:436-45. 2004..In addition, electron microscopy showed that myocardium in the TX group was most maintained. CONCLUSION: Bone marrow mononuclear cell transplantation had beneficial effects in doxorubicin-induced cardiomyopathy...
Spinal cord malperfusion caused by using the segmental clamp technique during descending aortic repair for chronic type B aortic dissectionMasashi Kawamura
Department of Cardiovascular Surgery, National Cardiovascular Center, 5 7 1 Fujishirodai, Suita, Osaka, 565 8565, Japan
Interact Cardiovasc Thorac Surg 7:146-8. 2008....
Surgical outcome of aortic arch repair for patients with Takayasu arteritisKaoru Matsuura
National Cardiovascular Center, Suita City, Osaka, Japan
Ann Thorac Surg 81:178-82. 2006..CONCLUSIONS: Surgical and late outcomes of aortic arch repair under circulatory arrest appear favorable, though late dilatation of the residual aorta is a matter of concern...
Redo off-pump coronary bypass grafting with arterial grafts for Kawasaki diseaseKaoru Matsuura
Department of Cardiovascular Surgery, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan
Heart Vessels 21:361-4. 2006..Off-pump total arterial revascularization is a safe and less invasive procedure at the time of redo operation, even for patients with Kawasaki disease...
Reconstruction of a friable posterior mitral annulus after removing a calcified artificial ring using flipover technique of the anterior mitral leafletShunsuke Saito
Department of Cardiovascular Surgery, National Cardiovascular Center, 5 7 1 Fujishirodai, Suita, Osaka, Japan
Gen Thorac Cardiovasc Surg 55:69-72. 2007..Postoperative ultrasonic cardiography revealed preservation of left ventricular function with no perivalvular leakage...
The impact of diabetic retinopathy on long-term outcome following coronary artery bypass graft surgeryTakayuki Ono
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
J Am Coll Cardiol 40:428-36. 2002..We sought to assess the impact of diabetic retinopathy on long-term outcome among patients with diabetes and multivessel coronary artery disease (MVD) following coronary artery bypass graft surgery (CABG)...
Prospective comparative study of brain protection in total aortic arch replacement: deep hypothermic circulatory arrest with retrograde cerebral perfusion or selective antegrade cerebral perfusionY Okita
Department of Cardiovascular Surgery and Neurology, National Cardiovascular Center, Osaka, Japan
Ann Thorac Surg 72:72-9. 2001..The purpose of this study was to compare the results of total aortic arch replacement using two different methods of brain protection, particularly with respect to neurologic outcome...
Continuous systemic perfusion improves outcome in one stage repair of obstructed aortic arch and associated cardiac malformationH Uemura
Department of Cardiovascular Surgery, National Cardiovascular Center, 5 7 1 Fujishirodai, Suita, 565 8565, Osaka, Japan
Eur J Cardiothorac Surg 20:603-7; discussion 607-8. 2001..To determine whether continuous systemic perfusion is of effective use when establishing primary repair of the aortic obstruction and associated cardiac malformations...
Transplantation of mesenchymal stem cells improves atrioventricular conduction in a rat model of complete atrioventricular blockMilki Yokokawa
Department of Internal Medicine, National Cardiovascular Center, Osaka, Japan
Cell Transplant 17:1145-55. 2008..In addition, local injection of MSC conditioned medium recovered AV conduction in 2 of 15 rats (13%). MSC transplantation improved AV conduction in a rat model of complete AVB, at least in part through antifibrotic paracrine effects...
Patency rate of the internal thoracic artery to the left anterior descending artery bypass is reduced by competitive flow from the concomitant saphenous vein graft in the left coronary arteryMasashi Kawamura
Department of Cardiovascular Surgery, National Cardiovascular Center, 5 7 1 Fujishirodai, Suita, Osaka 565 8565, Japan
Eur J Cardiothorac Surg 34:833-8. 2008..In the present study, we examined the impact of the patent SV graft to the left coronary artery on the long-term patency of the ITA to left anterior descending (LAD) artery bypass...
Prediction and incidence of atrial fibrillation after aortic arch repairKaoru Matsuura
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Ann Thorac Surg 81:514-8. 2006..CONCLUSIONS: Atrial fibrillation was not uncommon after aortic arch repair. Advanced age was the only preoperative risk factor for postoperative atrial fibrillation...
Durability and outcome of aortic valve replacement with mitral valve repair versus double valve replacementMasaki Hamamoto
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Ann Thorac Surg 75:28-33; discussion 33-4. 2003..MVP should not be performed in patients with rheumatic disease because of higher incidence of late failure...
Multivariate analysis of predictors of late stroke after total aortic arch repairKaoru Matsuura
Department of Cardiovascular Surgery, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan
Eur J Cardiothorac Surg 28:473-7. 2005..37, 95% CI: 2.30-12.52) as predictors of late stroke. CONCLUSIONS: Postoperative atrial fibrillation and preoperative prevalence of craniocervical lesions were found to be risk factors for late stroke after total aortic arch repair...
The effect of cryo-maze procedure on early and intermediate term outcome in mitral valve disease: case matched studyHiroyuki Nakajima
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Circulation 106:I46-I50. 2002..CM is a reliable and less invasive surgical option for the AF associated with mitral valve disease...
Is emergency total arch replacement with a modified elephant trunk technique justified for acute type A aortic dissection?Hirotaka Watanuki
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Ann Thorac Surg 84:1585-91. 2007..We assess the outcome of emergency total arch replacement with a modified elephant trunk technique for acute type A aortic dissection to clarify whether our aggressive approach is justified in certain patients...
Multiple and repetitive anastomotic pseudoaneurysms with polyarteritis nodosaYuki Nakamura
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Ann Thorac Surg 85:317-9. 2008..Infectious and congenital etiologies, as well as nonbacterial inflammatory diseases, were ruled out. Idiopathic aortitis or aortitis due to polyarteritis nodosa might fit the case...
Calphostin C induces expression of amphiregulin mRNA via reactive oxygen species in IEC-6 cellsY Miyazaki
Second Department of Internal Medicine, Osaka University Medical School, Suita, Japan
Life Sci 63:PL361-5. 1998..These results suggest that calphostin C can upregulate expression of AR mRNA via reactive oxygen species...
Transmural necrosis of the esophagus secondary to acute aortic dissectionK Minatoya
Department of Cardiovascular Surgery and Pathology, National Cardiovascular Center, Osaka, Japan
Ann Thorac Surg 69:1584-6. 2000..She died of multiple organ failure on postoperative day 74. Autopsy demonstrated transmural necrosis of the esophagus secondary to ischemia. Ischemia of the esophagus secondary to aortic dissection is extremely rare...
Predictive factors for mortality and cerebral complications in arteriosclerotic aneurysm of the aortic archY Okita
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Ann Thorac Surg 67:72-8. 1999..The incidence of cerebral complications is high in patients with aortic arch aneurysm...
[Aortoesophageal fistula due to ruptured thoracic aortic aneurysm: case report of successful primary reconstruction of esophagus]T Uchida
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Kyobu Geka 54:366-9. 2001..The patient recovered well postoperatively without infection...
[Posttransplant complications in cardiac transplant recipients at National Cardiovascular Center]Tomoko Kato
Department of Cardiovascular Medicine and Organ Transplantation, National Cardiovascular Center, Suita, Japan
Kyobu Geka 60:963-8. 2007..We have performed 21 cases of heart transplantation at our institution. We retrospectively reviewed the complications and its incidence in those post transplant course...
[Tricuspid valve replacement using right heart bypass in patient with liver cirrhosis]T Uchida
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Kyobu Geka 54:132-5. 2001..Although the mortality of the TVR in the patient with cirrhosis remains still high, this new technique seems to provide better outcome in this kind of patients...
[Aortic dissection in pregnant woman with the Marfan syndrome]T Uchida
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Japan
Kyobu Geka 55:693-6. 2002..To prevent hemorrhagic complications under systemic heparinization, simultaneous hysterectomy should be considered as one option...
Long-term pathological changes of expanded polytetrafluoroethylene (ePTFE) suture in the human heartK Minatoya
Department of Cardiovascular Surgery and Pathology, National Cardiovascular Center, Suita, Osaka, Japan
J Heart Valve Dis 10:139-42. 2001..The suture was totally encapsulated with host tissues composed of dense fibrous tissue covered with endothelial cells...
Is prompt surgical treatment of an abdominal aortic aneurysm justified for someone in their eighties?Masato Tochii
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Ann Thorac Cardiovasc Surg 15:23-30. 2009..The aim of this study is to review the early and long-term results and quality of life after abdominal aortic aneurysm (AAA) surgery in octogenarians to justify our prompt surgical intervention...
Observation of cavitation in a mechanical heart valve in a total artificial heartHwansung Lee
Department of Artificial Organs, Research Institute, National Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565, Japan
ASAIO J 50:205-10. 2004..The mechanism leading to the development of cavitation bubbles depended on the valve closing velocity and the valve stop geometry. Most of the cavitation bubbles were observed around the valve stop and were generated by the squeeze flow...
Long-term outcome of right ventricular outflow tract reconstruction using a handmade tri-leaflet conduitMasahiro Koh
Department of Cardiovascular Surgery, National Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565, Japan
Eur J Cardiothorac Surg 27:807-14. 2005..Longer follow-up is needed to determine how well ePTFE leaflets will fare...
Biventricular repair for right atrial isomerismMasahiro Koh
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Ann Thorac Surg 81:1808-16; discussion 1816. 2006..CONCLUSIONS: Biventricular repair provided good long-term outcomes in patients with right atrial isomerism. In selected circumstances, biventricular repair is an acceptable alternative to the Fontan procedure...
The impact of mitral valve surgery combined with maze procedureAkinobu Itoh
Department of Cardiovascular Surgery, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan
Eur J Cardiothorac Surg 29:1030-5. 2006....
Impact of age at Fontan completion on postoperative hemodynamics and long-term aerobic exercise capacity in patients with dominant left ventricleShuichi Shiraishi
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Ann Thorac Surg 87:555-60; discussion 560-1. 2009..We investigated whether age at Fontan completion affects subsequent hemodynamics and exercise capacity in patients with a dominant left ventricle followed up for more than 5 years...
Effect of maze procedure in patients with atrial fibrillation undergoing valve replacementKo Bando
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
J Heart Valve Dis 11:719-24; discussion 725. 2002..03). CONCLUSION: The combined maze procedure and valve replacement is safe and effective in selected patients. Restoration of regular rhythm significantly reduced the incidence of late stroke...
Perioperative advantages of off-pump coronary artery bypass graftingMichiko Ishida
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Japan
Circ J 66:795-9. 2002..There was no significant difference in graft patency between the groups (95.6% vs 94.9%). OPCAB reduced the mortality and morbidity of coronary revascularization, with a shorter operating time and more rapid recovery from surgery...
Allogeneic injection of fetal membrane-derived mesenchymal stem cells induces therapeutic angiogenesis in a rat model of hind limb ischemiaShin Ishikane
Department of Perinatology, National Cardiovascular Center Research Institute, Suita, Osaka, Japan
Stem Cells 26:2625-33. 2008..Thus, allogeneic injection of FM-MSC may be a new therapeutic strategy for the treatment of severe peripheral vascular disease. Disclosure of potential conflicts of interest is found at the end of this article...
Activation of cardiac progenitor cells through paracrine effects of mesenchymal stem cellsChiaki Nakanishi
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center Research Institute, 5 7 1 Fujishirodai, Suita, Osaka 565 8565, Japan
Biochem Biophys Res Commun 374:11-6. 2008..In conclusion, MSC-derived conditioned medium had protective effects on CPC and enhanced their migration and differentiation...
Implantation of collar-reinforced sumit valve for patient with large calcified mass obstructing the mitral valve orificeHiroaki Sakamoto
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Jpn J Thorac Cardiovasc Surg 51:672-4. 2003..The SuMit valve is designed to be placed in a supraannular position, and is useful to prevent valves from getting stuck...
Congenital diverticulum of the left ventricleT Uchida
Department of Cardiovascular Surgery, National Cardiovascular Center, Fujishirodai, Suita, Osaka 565-8565, Japan
Jpn J Thorac Cardiovasc Surg 49:244-6. 2001..Considering the potential risks such as rupture, systemic thromboembolism, and arrhythmia, an early surgical intervention should be employed for this rare abnormality even in a child without clinical symptoms...
Redo operation for thoracoaortic aneurysm after entire aortic replacementA Ingu
Department of Cardiovascular Surgery and Radiology, National Cardiovascular Center, Suita, Osaka, Japan
Ann Thorac Surg 72:1766-7. 2001..The intercostal arteries were reconstructed end-to-end using small-caliber interposition grafts to the aortic prosthesis. Preoperative magnetic resonance angiography identified the artery of Adamkiewicz and facilitated its preservation...
Which factors predict the recovery of natural heart function after insertion of a left ventricular assist system?A Mano
Department of Organ Transplantation, National Cardiovascular Center, Osaka, Japan
J Heart Lung Transplant 27:869-74. 2008..In this study we investigated reliable predictors of LVAS weaning...
Ventricular outflow tracts after Kawashima intraventricular rerouting for double outlet right ventricle with subpulmonary ventricular septal defectY Kawahira
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Eur J Cardiothorac Surg 16:26-31. 1999....
Renewal of the Fontan circulation with concomitant surgical intervention for atrial arrhythmiaY Kawahira
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Ann Thorac Surg 71:919-21. 2001..Atrial arrhythmia remains one of the major complications in the longer term after the Fontan procedure...
Partial anomalous pulmonary venous connection to the superior vena cavaAtsushi Nakahira
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Ann Thorac Surg 82:978-82. 2006..Patients with particularly high insertion of anomalous pulmonary veins should be treated and followed with specific caution for preserving an unobstructed caval pathway...
Rationale for off-pump coronary revascularization to small branches--angiographic study of 1,283 anastomoses in 408 patientsKaoru Matsuura
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Ann Thorac Surg 77:1530-4. 2004..1% and 95.8% vs. end-to-side 96.3% and 86.3%) in group S. CONCLUSIONS: OPCAB to small coronary artery branches with arterial grafts provided satisfactory graft patency and stenosis free rates...
Early adaptation of the left internal thoracic artery as a blood source of y-composite radial artery grafts in off-pump coronary artery bypass graftingOsamu Tagusari
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Heart Surg Forum 6:E93-8. 2003..006). CONCLUSION: These results demonstrate the early adaptation of the LITA as a blood source of the Y-composite RA graft in OPCAB and the rationale for using the LITA as a single blood source for total coronary artery revascularization...
Adrenomedullin enhances angiogenic potency of bone marrow transplantation in a rat model of hindlimb ischemiaTakashi Iwase
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center Research Institute, Suita, Osaka, Japan
Circulation 111:356-62. 2005..This effect may be mediated in part by the angiogenic potency of AM itself and the beneficial effects of AM on the survival, adhesion, and differentiation of transplanted MNCs...
Partial left ventriculectomy--The Third International Registry Report 2002Akira T Kawaguchi
Society for Cardiac Volume Reduction, Cardiovascular Surgery, Tokai University School of Medicine, Bohseidai, Isehara, Japan
J Card Surg 18:S33-42. 2003..An international registry of partial left ventriculectomy (PLV) has been expanded, updated, and refined to include 440 cases voluntarily reported from 51 hospitals in 11 countries...
Aortic valve replacement concomitant with multiple extra-anatomical bypasses for a patient with aortic valve insufficiency having Takayasu's arteritisAkinobu Itoh
Department of Cardiovascular Surgery, National Cardiovascular Center, 5-7-1 Fujishirodai, SITA, Osaka 565-8565, Japan
Eur J Cardiothorac Surg 27:1114. 2005
A novel application of myocardial contrast echocardiography to evaluate angiogenesis by autologous bone marrow cell transplantation in chronic ischemic pig modelHiroko Fujii
Department of Organ Transplantation, National Cardiovascular Center, Osaka, Japan
J Am Coll Cardiol 43:1299-305. 2004..We investigated the feasibility of myocardial contrast echocardiography (MCE) to evaluate regional perfusion after bone marrow cell transplantation...
Transplantation of mesenchymal stem cells attenuates myocardial injury and dysfunction in a rat model of acute myocarditisShunsuke Ohnishi
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center Research Institute, Fujishirodai 5 7 1, Osaka 565 8565, Japan
J Mol Cell Cardiol 42:88-97. 2007..MSC transplantation attenuated myocardial injury and dysfunction in a rat model of acute myocarditis, at least in part through paracrine effects of MSC...
G-CSF promotes bone marrow cells to migrate into infarcted mice heart, and differentiate into cardiomyocytesShinya Fukuhara
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center, Osaka, Japan
Cell Transplant 13:741-8. 2004..8+/-6.1/mm2) (p = 0.01). G-CSF increased the survival rate after infarction. G-CSF promoted BMC to migrate into the infarcted border area. Bone marrow was one of the origins of regenerated cardiomyocytes...
Total arch replacement through re-median sternotomy after coronary surgeryHitoshi Inafuku
Department of Cardiovascular Surgery, National Cardiovascular Center, 5 7 1 Fujishirodai, Suita, Osaka 565 8565, Japan
Gen Thorac Cardiovasc Surg 55:473-5. 2007....
Contrast sonography enables noninvasive and quantitative assessment of neovascularization after stem cell transplantationKentaro Otani
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center Research Institute, Suita, Japan
Ultrasound Med Biol 34:1893-900. 2008..01; vs. capillary density: r = 0.52, p < 0.05). The results of our study imply that the contrast sonography-derived beta-ratio is a useful parameter that reflects the perfusion after cell transplantation in ischemic hindlimb...
Long-term results of saphenous vein graft for coronary stenosis caused by Kawasaki diseaseYuko Wakisaka
Department of Pediatrics, National Cardiovascular Center, Suita, Japan
Circ J 73:73-7. 2009..Although saphenous vein grafts (SVG) have been used from 1975 to treat coronary stenosis caused by Kawasaki disease, long-term results after more than 20 years remain unknown...
[Complications and problems of acute care in patients undergoing heart transplantation]Hideaki Imanaka
Intensive Care Unit, National Cardiovascular Center, Suita, Japan
Kyobu Geka 60:958-62. 2007..Acute renal insufficiency occurred in 8 patients, while 1 patient needed 12 hours of continuous hemodiafiltration. All of the patients received infusions atrial natriuretic peptide and restored renal insufficiency...
Pericardiectomy for constrictive pericarditis using the harmonic scalpelT Uchida
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Ann Thorac Surg 72:924-5. 2001..This new device has many advantages including no muscular stimulation, low heat, a smokeless field, and easy hemostasis. The Harmonic Scalpel is beneficial for dissection of thickened pericardium...
Pathological role of angiostatin in heart failure: an endogenous inhibitor of mesenchymal stem-cell activationK Yamahara
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center Research Institute, Fujishirodai 5 7 1, Suita, Osaka, Japan
Heart 95:283-9. 2009....
[Reconstruction of the right ventricular outflow tract in patients undergoing the Ross procedure]H Uemura
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Japan
Kyobu Geka 54:683-9. 2001..Use of a homograft, however, could be preferred in a selected group of patients with deleterious circumstances on the postoperative circulation...
Cavitation phenomenon in monoleaflet mechanical heart valves with electrohydraulic total artificial heartH Lee
Department of Artificial Organs, Research Institute, National Cardiovascular Center, Suita, Osaka, Japan
Int J Artif Organs 27:779-86. 2004..The formation of cavitation bubbles depended on the valve closing velocity and the valve leaflet geometry. From a viewpoint of squeeze flow, a low closing velocity and a small size of the valve stop could minimize cavitation...
Competitive flow in arterial composite grafts and effect of graft arrangement in Off-Pump coronary revascularizationHiroyuki Nakajima
Department of Cardiovascular Surgery, National Cardiovascular Center, 5 7 1 Fujishirodai, Suita, Osaka 565 8565, Japan
Ann Thorac Surg 78:481-6. 2004....
Functional biventricular repair using left ventricle-pulmonary artery conduit in patients with discordant atrioventricular connections and pulmonary outflow tract obstruction-does conduit obstruction maintain tricuspid valve function?Masahiro Koh
Department of Cardiovascular Surgery, National Cardiovascular Center, 5 7 1 Fujishiro dai, 565 8565 Suita, Osaka, Japan
Eur J Cardiothorac Surg 26:767-72. 2004....
Failure to prevent progressive dilation of ascending aorta by aortic valve replacement in patients with bicuspid aortic valve: comparison with tricuspid aortic valveHisayo Yasuda
Department of Cardiology, National Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565, Japan
Circulation 108:II291-4. 2003..CONCLUSIONS: AVR could not prevent progressive aortic dilation in BAV. Since the aorta did not dilate in TAV, progressive aortic dilation in BAV seems mainly due to the fragility of the aortic wall rather than hemodynamic factors...
Effect of hypoxia on gene expression of bone marrow-derived mesenchymal stem cells and mononuclear cellsShunsuke Ohnishi
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center, 5 7 1 Fujishirodai, Osaka 565 8565, Japan
Stem Cells 25:1166-77. 2007..Our results may provide information on the differential molecular mechanisms regulating the properties of MSC and MNC under ischemic conditions. Disclosure of potential conflicts of interest is found at the end of this article...
Observation of cavitation bubbles in monoleaflet mechanical heart valvesHwansung Lee
Department of Artificial Organs, Research Institute, National Cardiovascular Center, 5 7 1 Fujishiro dai, Suita, Osaka 565 8565, Japan
J Artif Organs 7:121-7. 2004..From the viewpoint of squeeze flow, the Björk-Shiley valve was less likely to cause blood cell damage than the Medtronic Hall valve in our EHTAH...
Development of a compact portable driver for a pneumatic ventricular assist deviceTomohiro Nishinaka
Department of Artificial Organs, National Cardiovascular Center Research Institute, 5 7 1 Fujishirodai, Suita 565 8565, Japan
J Artif Organs 10:236-9. 2007..We conclude that this newly-developed compact portable driver can provide a better quality of life and improved safety for patients using protracted pneumatic VAD support...
Multiple off-pump coronary revascularization with "aorta no-touch " technique using composite and sequential methodsJunjiro Kobayashi
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Heart Surg Forum 5:114-8. 2002..In the present study, we report the initial results of an "aorta no-touch " technique using an in-situ graft and composite and sequential grafting methods...
Integrated total arch replacement using selective cerebral perfusion: a 6-year experienceHiroaki Sasaki
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Ann Thorac Surg 83:S805-10; discussion S824-31. 2007..The purpose of this study was to evaluate the recent outcome of integrated total arch replacement using antegrade selective cerebral perfusion with right axillary artery perfusion...
Impact of preoperative and postoperative atrial fibrillation on outcome after mitral valvuloplasty for nonischemic mitral regurgitationKo Bando
Department of Cardiovascular Surgery, National Cardiovascular Center, 5 7 1 Fujishirodai, Suita, Osaka 565 8565, Japan
J Thorac Cardiovasc Surg 129:1032-40. 2005..We sought to determine the impact of preoperative or postoperative atrial fibrillation on survival, stroke, and cardiac function after mitral valvuloplasty for mitral regurgitation...
Impact of Cox maze procedure on outcome in patients with atrial fibrillation and mitral valve diseaseKo Bando
Departments of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
J Thorac Cardiovasc Surg 124:575-83. 2002..We sought to determine whether the Cox maze procedure provides additional benefit to patients with atrial fibrillation undergoing mitral valve operations...
Predictive factors for the intermediate-term patency of arterial grafts in aorta no-touch off-pump coronary revascularizationHiroyuki Nakajima
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Eur J Cardiothorac Surg 32:711-7. 2007..To establish the optimal graft design, we examined detailed characteristics of the arterial composite and sequential grafts, and sought to delineate the risk factors of graft occlusion due to insufficient bypass flow...
Adrenomedullin: angiogenesis and gene therapyNoritoshi Nagaya
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center Research Institute, 5 7 1 Fujishirodai, Suita, Osaka 565 8565, Japan
Am J Physiol Regul Integr Comp Physiol 288:R1432-7. 2005..These results suggest that in vivo and in vitro transfer of AM gene using gelatin may be applicable for intractable cardiovascular disease...
Functional angiographic evaluation of individual, sequential, and composite arterial graftsHiroyuki Nakajima
Department of Cardiovascular Surgery and Cardiology, National Cardiovascular Center, Osaka, Japan
Ann Thorac Surg 81:807-14. 2006..To help optimize graft arrangement, we examined the effects of target vessel characteristics, conduit type, and interactions between the target vessels on the occurrence of flow reversal or occlusion...
Total arterial off-pump coronary revascularization with only internal thoracic artery and composite radial artery graftsJunjiro Kobayashi
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Heart Surg Forum 6:30-7. 2002..We evaluated the initial experience with this method by clinical and angiographic study...
Comparison of angiogenic potency between mesenchymal stem cells and mononuclear cells in a rat model of hindlimb ischemiaTakashi Iwase
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center Research Institute, Suita, Osaka, Japan
Cardiovasc Res 66:543-51. 2005..Thus, MSC transplantation may be a new therapeutic strategy for the treatment of severe peripheral vascular disease...
Celiprolol, a vasodilatory beta-blocker, inhibits pressure overload-induced cardiac hypertrophy and prevents the transition to heart failure via nitric oxide-dependent mechanisms in miceYulin Liao
Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Osaka, Japan
Circulation 110:692-9. 2004..Thus, we aimed to clarify whether celiprolol attenuates both myocardial hypertrophy and heart failure via the NO-signal pathway...
Determinants for successful sequential radial artery grafting to the left circumflex and right coronary arteriesHiroyuki Nakajima
Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, 5 7 1 Fujishirodai, Suita, Osaka 565 8565, Japan
Interact Cardiovasc Thorac Surg 12:125-9. 2011..1% (P<0.0001). In sequential RAG, severity of stenosis in the most distal target had the significant impact on prevention of competitive flow and long-term patency to all targets...
Involvement of tazarotene-induced gene 1 in proliferation and differentiation of human adipose tissue-derived mesenchymal stem cellsS Ohnishi
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center Research Institute, Osaka, Japan
Cell Prolif 42:309-16. 2009..Therefore, we aimed to compare the proliferation and gene expression profile of cultured human visceral ASC (VASC) and subcutaneous ASC (SASC), and to identify a novel gene involved in proliferation and differentiation of ASC...
A case of interleukin-6-producing malignant fibrous histiocytoma originating in the heartH Deguchi
Third Department of Internal Medicine, Nissay Hospital, Nippon Life Saiseikai Foundation, Osaka, Japan
Jpn J Clin Oncol 29:382-6. 1999..This was confirmed by immunohistochemical analysis. To our knowledge, this is the first report demonstrating interleukin-6 production by a cardiac malignant fibrous histiocytoma...
Heart-type fatty acid binding protein is a novel prognostic marker in patients with non-ischaemic dilated cardiomyopathyK Komamura
Department of Cardiovascular Dynamics, National Cardiovascular Centre Research Institute, Suita, Japan
Heart 92:615-8. 2006..To determine whether concentrations of heart-type fatty acid binding protein (H-FABP) measured before hospital discharge predict critical cardiac events in patients with idiopathic dilated cardiomyopathy (DCM)...
[Developing the best and the brightest in academic surgery for next generation]K Bando
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan
Nippon Geka Gakkai Zasshi 102:274-6. 2001..The training system should be further refined, and a sufficient number of positions with appropriate remuneration must be mode available...
Expression of lectin-like oxidized low-density lipoprotein receptor-1 in allografted heartsM Suga
Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center, Suita, Japan
Transplant Proc 36:2440-2. 2004..The results indicate that alloimmune responses induce up-regulation of LOX-1 mRNA in transplanted hearts. Increased LOX-1 may be involved in the progression of obstructive vascular changes...
Mechanism of improvement in exercise capacity after the maze procedure combined with mitral valve surgeryS Yuda
Division of Cardiology, National Cardiovascular Centre, Osaka, Japan
Heart 90:64-9. 2004..CONCLUSIONS: Improvement in exercise capacity may not be caused by restored SR and atrial contraction but may at least partly relate to the reduction of left atrial size and improvement of haemodynamic variables by the surgery...
[Aortic valve-sparing root reconstruction in Marfan syndrome]H Ogino
Department of Cardiovascular Surg, National Cardiovascular Center, Suita, Japan
Kyobu Geka 55:639-43. 2002..Aortic valve-sparing root reconstruction is applicable in Marfan patients, although the indication should be cautious. Close observation is needed for recurrence of aortic regurgitation...
PPARgamma agonists inhibit cell growth and suppress the expression of cyclin D1 and EGF-like growth factors in ras-transformed rat intestinal epithelial cellsS Kitamura
Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University, Osaka, Japan
Int J Cancer 94:335-42. 2001..These findings suggest that reduction of EGF-like growth factors and cyclin D1 through the suppression of AP-1 and Ets may be 1 mechanism whereby PPARgamma inhibits their growth...
