Affiliation: National Institute of Genetics
- An essential function of Grr1 for the degradation of Cln2 is to act as a binding core that links Cln2 to Skp1T Kishi
Laboratory of Mutagenesis, Department of Molecular Genetics, National Institute of Genetics, Mishima, Shizuoka ken 411 8540, Japan
J Cell Sci 111:3655-61. 1998..Furthermore, Skp1 associated in vivo with phosphorylated Cln2 in a Grr1-dependent manner. These data suggest that Grr1 is required for degradation of Cln2 through linking phosphorylated Cln2 to Skp1 in a SCFGrr1 complex...
- Grr1 functions in the ubiquitin pathway in Saccharomyces cerevisiae through association with Skp1T Kishi
Department of Molecular Genetics, National Institute of Genetics, Shizuoka ken, Japan
Mol Gen Genet 257:143-8. 1998..Furthermore, Grr1 bound Skp1 directly in vitro. These results strongly suggest that Grr1 functions in the ubiquitin pathway through association with Skp1...
- Isolation of a candidate gene, CAB1, for cholesterol transport to mitochondria from the c-ERBB-2 amplicon by a modified cDNA selection methodN Akiyama
Genetics Division, National Cancer Center Research Institute, Tokyo, Japan
Cancer Res 57:3548-53. 1997..It was established that multiple overexpressed genes are frequently present in a single amplicon...