Takemi Kimura

Summary

Affiliation: NHO Kikuchi Hospital
Location: Koshi, Japan
URL: http://www.labome.org//exp/japan/national/kimura/takemi-kimura-1552127.html
Summary:
1. I graduated from Miyazaki Medical University in 1984, worked as training doctor for 3 years, entered the graduate school of Kumamoto University School of Medicine and learned and studied neuropathology of Alzheimer
Publications:
1. Existence of senile plaques in the brains of elderly leprosy patients. Lancet 1993;342:1364
2. Re-evaluation of classic senile plaques by three-dimensional analysis. J Neurol 1994;241:624-627
3. Are advanced glycation end-products associated with amyloidosis in Alzheimers disease ? Neuroreport 1995;6:866-868
4. Accumulation of advanced glycation end products of the Maillard reaction with age in human hippocampal neurons. Neurosci Lett 1996;208:53-56
5. Sequential changes of tau-site-specific phosphorylation during development of paired helical filaments. Dementia 1996;7:177-181
6. Identification of advanced glycation end products of the Maillard reaction in Picks disease. Neurosci Lett 1996;219:95-98
7. Apolipoprotein E epsilon2 allele and early onset schizophrenia. Neurosci Lett 1997;231:53-55
8. Localization of identified advanced glycation end product structures, N epsilon (carboxymethyl)lysine and pentosidine, in age-related inclusions in human brains. Pathol Int 1998;48:575-579
9. Phosphorylation of MARCKS in Alzheimer disease brains. Neuroreport 2000;11:869-873
10. Apolipoprotein E epsilon3 allele is not a risk factor of schizophrenia: a study of 314 Japanese patients. Neuropsychobiology 2000;42:66-68
11. Apolipoprotein E epsilon4 and tardive dyskinesia in a Japanese population. J Psychiat Res 2000;34:329-332
12. Identification of an aging-related spherical inclusion in the human brain. Pathol Int 2002;52:636-642
13. Pilot study of pharmacological treatment for frontotemporal dementia: effect of Yokukansan on behavioral symptoms. Psychiatry Clin Neurosci 2010;64:207-210
14. Effect of ferulic acid and Angelica archangelica extract on behavioral and psychological symptoms of dementia in frontotemporal lobar degeneration and dementia with Lewy bodies. Geriatr Gerontol Int 2011;11:309-314

Publications

  1. ncbi Apolipoprotein E epsilon2 allele and early onset schizophrenia
    T Kimura
    Department of Neuropsychiatry, Kumamoto University School of Medicine, Honjo, Japan
    Neurosci Lett 231:53-5. 1997
  2. ncbi Localization of identified advanced glycation end-product structures, N epsilon(carboxymethyl)lysine and pentosidine, in age-related inclusions in human brains
    T Kimura
    Department of Neuropsychiatry, Kumamoto University School of Medicine, Japan
    Pathol Int 48:575-9. 1998
  3. ncbi Apolipoprotein E epsilon3 allele is not a risk factor of schizophrenia: a study of 314 Japanese patients
    T Kimura
    Department of Neuropsychiatry, Kumamoto University School of Medicine, Kumamoto, Japan
    Neuropsychobiology 42:66-8. 2000
  4. ncbi Apolipoprotein E epsilon4 and tardive dyskinesia in a Japanese population
    T Kimura
    Department of Neuropsychiatry, Kumamoto University School of Medicine, Honjo 1 1 1, Kumamoto 860 8556, Japan
    J Psychiatr Res 34:329-32. 2000
  5. ncbi Identification of an aging-related spherical inclusion in the human brain
    Takemi Kimura
    Department of Psychiatry, Kumamoto University School of Medicine, Saga, Japan
    Pathol Int 52:636-42. 2002
  6. ncbi Pilot study of pharmacological treatment for frontotemporal dementia: effect of Yokukansan on behavioral symptoms
    Takemi Kimura
    Division of Clinical Research, National Hospital Organization Kikuchi Hospital, 208 Fukuhara, Koshi, Kumamoto 861 1116, Japan
    Psychiatry Clin Neurosci 64:207-10. 2010
  7. ncbi Effect of ferulic acid and Angelica archangelica extract on behavioral and psychological symptoms of dementia in frontotemporal lobar degeneration and dementia with Lewy bodies
    Takemi Kimura
    Division of Clinical Research, National Hospital Organization Kikuchi Hospital, Kumamoto, Japan
    Geriatr Gerontol Int 11:309-14. 2011

Detail Information

Publications7

  1. ncbi Apolipoprotein E epsilon2 allele and early onset schizophrenia
    T Kimura
    Department of Neuropsychiatry, Kumamoto University School of Medicine, Honjo, Japan
    Neurosci Lett 231:53-5. 1997
    ..These results suggest that ApoE epsilon2 protects against early onset schizophrenia, and that ApoE epsilon4 is not involved in the development of schizophrenia in Japanese...
  2. ncbi Localization of identified advanced glycation end-product structures, N epsilon(carboxymethyl)lysine and pentosidine, in age-related inclusions in human brains
    T Kimura
    Department of Neuropsychiatry, Kumamoto University School of Medicine, Japan
    Pathol Int 48:575-9. 1998
    ..As CML and pentosidine are glycoxidation products among AGE, the results suggest that glycation and/or oxidation may be involved in the formation of lipofuscin granules and corpora amylacea...
  3. ncbi Apolipoprotein E epsilon3 allele is not a risk factor of schizophrenia: a study of 314 Japanese patients
    T Kimura
    Department of Neuropsychiatry, Kumamoto University School of Medicine, Kumamoto, Japan
    Neuropsychobiology 42:66-8. 2000
    ..In contrast to the report from Taiwan, our findings and results of the majority of previous studies suggest no effects of ApoE alleles on the development of schizophrenia...
  4. ncbi Apolipoprotein E epsilon4 and tardive dyskinesia in a Japanese population
    T Kimura
    Department of Neuropsychiatry, Kumamoto University School of Medicine, Honjo 1 1 1, Kumamoto 860 8556, Japan
    J Psychiatr Res 34:329-32. 2000
    ..These findings do not clearly demonstrate a certain association between TD and the epsilon4 allele, but may preliminarily reveal a difference in influence of this allele on the development of TD between males and females...
  5. ncbi Identification of an aging-related spherical inclusion in the human brain
    Takemi Kimura
    Department of Psychiatry, Kumamoto University School of Medicine, Saga, Japan
    Pathol Int 52:636-42. 2002
    ..The presence of the inclusion was confirmed using immunoelectron microscopy. These findings show a possibility that the inclusion is a novel aging-related structure in the human brain...
  6. ncbi Pilot study of pharmacological treatment for frontotemporal dementia: effect of Yokukansan on behavioral symptoms
    Takemi Kimura
    Division of Clinical Research, National Hospital Organization Kikuchi Hospital, 208 Fukuhara, Koshi, Kumamoto 861 1116, Japan
    Psychiatry Clin Neurosci 64:207-10. 2010
    ..The results indicate that Yokukansan can alleviate the behavioral symptoms of frontotemporal dementia. (The clinical trial registration number is UMIN000002704)...
  7. ncbi Effect of ferulic acid and Angelica archangelica extract on behavioral and psychological symptoms of dementia in frontotemporal lobar degeneration and dementia with Lewy bodies
    Takemi Kimura
    Division of Clinical Research, National Hospital Organization Kikuchi Hospital, Kumamoto, Japan
    Geriatr Gerontol Int 11:309-14. 2011
    ..The present study investigated the efficacy of Feru-guard in the treatment of behavioral and psychological symptoms in frontotemporal lobar degeneration and dementia with Lewy bodies...