Research Topics
| Haruhisa KatoSummaryAffiliation: National Institute of Advanced Industrial Science and Technology Country: Japan Publications
| Collaborators
|
Detail Information
Publications
Characterization of fullerene colloidal suspension in a cell culture medium for in vitro toxicity assessmentHaruhisa Kato
Polymer Standards Section Japan PSSJ, National Metrology Institute of Japan NMIJ, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba Central 5, Higashi 1 1 1, Tsukuba, Ibaraki, 305 8565 Japan
Mol Biosyst 6:1238-46. 2010..Since carbon nanomaterials with different geometric structures exhibit quite different cytotoxicity and bioactivity, these results are important for in vitro toxicity assessment...
Reliable size determination of nanoparticles using dynamic light scattering method for in vitro toxicology assessmentHaruhisa Kato
Polymer Standards Section Japan, National Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology, Tsukuba Central 5, Tsukuba, Ibaraki 305 8565, Japan
Toxicol In Vitro 23:927-34. 2009..Furthermore, TiO(2) secondary nanoparticle suspensions are well dispersed with slow gravity settling, no agglomeration, with the diffusion process as the primary transport mode of particles to cells...
Size effect on UV-Vis absorption properties of colloidal C(60) particles in waterHaruhisa Kato
National Metrology Institute of Japan, Higashi, Tsukuba, Ibaraki, Japan
Phys Chem Chem Phys 11:4946-8. 2009..An obvious size effect of colloidal C(60) particles on UV-Vis absorption spectra was found after size fractionation of colloidal C(60) particles in water using the Field Flow Fractionation method...
Dispersion characteristics of various metal oxide secondary nanoparticles in culture medium for in vitro toxicology assessmentHaruhisa Kato
Polymer Standards Section Japan, National Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology, Tsukuba Central 5, Higashi 1 1 1, Tsukuba, Ibaraki 305 8565, Japan
Toxicol In Vitro 24:1009-18. 2010..The estimation of particle dynamics in culture medium using this method would be significant to recognize the inherent toxicity of nanoparticles...
Effects of ultrafine TiO2 particles on gene expression profile in human keratinocytes without illumination: involvement of extracellular matrix and cell adhesionKatsuhide Fujita
Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, Onogawa 16 1, Tsukuba, Ibaraki 305 8569, Japan
Toxicol Lett 191:109-17. 2009..These results suggest that the ultrafine TiO(2) particles without illumination have no significant impact on ROS-associated oxidative damage, but affect the cell-matrix adhesion in keratinocytes for extracellular matrix remodeling...
Cellular responses induced by cerium oxide nanoparticles: induction of intracellular calcium level and oxidative stress on culture cellsMasanori Horie
Health Research Institute, National Institute of Advanced Industrial Science and Technology AIST, 1 8 31, Midorigaoka, Ikeda, Osaka 563 8577, Japan
J Biochem 150:461-71. 2011..These results suggest that CeO(2) nanoparticles have a potential to induce intracellular oxidative stress and increase the intracellular Ca(2+) level, but these influences are small...
Evaluation of cellular influences of platinum nanoparticles by stable medium dispersionMasanori Horie
Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka 807 8555, Japan
Metallomics 3:1244-52. 2011..These results suggest that the physically and chemically inactive cellular influences of platinum nanoparticles are small...
In vitro evaluation of cellular responses induced by stable fullerene C60 medium dispersionMasanori Horie
Health Research Institute HRI, National Institute of Advanced Industrial Science and Technology AIST, 1 8 31 Midorigaoka, Ikeda, Osaka 563 8577, Japan
J Biochem 148:289-98. 2010..The results obtained from this study indicate that C60 has oxidative stress induction potential. Further examinations including in vivo studies are necessary for a more accurate evaluation of biological influences by C60...
Cellular responses by stable and uniform ultrafine titanium dioxide particles in culture-medium dispersions when secondary particle size was 100 nm or lessMasanori Horie
Health Technology Research Center HTRC, National Institute of Advanced Industrial Science and Technology AIST, Ikeda, Osaka, Japan
Toxicol In Vitro 24:1629-38. 2010..As a result, although the ultrafine TiO(2) particles induce some cellular responses, these cellular responses to ultrafine TiO(2) are weaker than those of other cytotoxic ultrafine metal oxide particles, such as nickel oxide...
Association of zinc ion release and oxidative stress induced by intratracheal instillation of ZnO nanoparticles to rat lungHiroko Fukui
Health Research Institute HRI, National Institute of Advanced Industrial Science and Technology AIST, Ikeda, Osaka, Japan
Chem Biol Interact 198:29-37. 2012..Intracellular ROS level had a high correlation with intracellular Zn(2+) level. ZnO nanoparticles will stay in the lung and continually release zinc ion, and thus stronger oxidative stress is induced...
Chromium(III) oxide nanoparticles induced remarkable oxidative stress and apoptosis on culture cellsMasanori Horie
Health Research Institute, National Institute of Advanced Industrial Science and Technology, 1 8 31 Midorigaoka, Ikeda, Osaka 563 8577, Japan
Environ Toxicol 28:61-75. 2013..The cellular influences of Cr(2)O(3) nanoparticles matched those of hexavalent chromium. In conclusion, Cr(2)O(3) nanoparticles have a high cytotoxic potential...
Certification and uncertainty evaluation of the certified reference materials of poly(ethylene glycol) for molecular mass fractions by using supercritical fluid chromatographyKayori Takahashi
Materials Characterization Division, National Metrology Institute of Japan, Tsukuba Central 5, 1 1 1 Higashi, Tsukuba, Ibaraki, 305 8565, Japan
Anal Bioanal Chem 391:2079-87. 2008..Especially, it is suitable for calibration against both masses and intensities for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry...
Development of a standard method for nanoparticle sizing by using the angular dependence of dynamic light scatteringKayori Takahashi
Polymer Standards Section, Materials Characterization Division, National Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology, Higashi, Tsukuba, Ibaraki, Japan
Anal Sci 27:751. 2011..The resulting particle sizes were consistent with those measured by using a differential mobility analyzer and those obtained by pulsed-field gradient nuclear magnetic resonance measurements...
Ultrafine NiO particles induce cytotoxicity in vitro by cellular uptake and subsequent Ni(II) releaseMasanori Horie
Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, 1 8 31, Midorigaoka, Ikeda, Osaka 563 8577, Japan
Chem Res Toxicol 22:1415-26. 2009..Taken together, the present results suggest that the intracellular Ni(2+) release could be an important factor that determines the cytotoxicity of NiO. Ultrafine NiO is more cytotoxic than fine NiO in vitro...
Calibration of an evaporative light-scattering detector as a mass detector for supercritical fluid chromatography by using uniform Poly(ethylene glycol) oligomersKayori Takahashi
National Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology, Tsukuba Central 5, 1 1 1 Higashi, Tsukuba, Ibaraki 305 8565, Japan
J Chromatogr A 1193:146-50. 2008..The average molecular mass was shifted to a higher value by several percentage points after calibration of the ELSD...
Cellular effects of manufactured nanoparticles: effect of adsorption ability of nanoparticlesMasanori Horie
Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka, Japan
Arch Toxicol 87:771-81. 2013..The flow field-flow fractionation method is one of the efficient techniques for determining proteins on the surface of nanoparticles. The cellular effects caused by nanoparticles should be carefully considered...
