Yukihide Kanemitsu

Summary

Affiliation: National Cancer Center
Country: Japan

Publications

  1. doi request reprint D3 Lymph Node Dissection in Right Hemicolectomy with a No-touch Isolation Technique in Patients With Colon Cancer
    Yukihide Kanemitsu
    Department of Gastroenterological Surgery, Aichi Cancer Center, Nagoya, Japan
    Dis Colon Rectum 56:815-24. 2013
  2. ncbi request reprint A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in Japan
    Keitaro Matsuo
    Division of Epidemiology and Prevention, Aichi Cancer Center, Nagoya, Japan
    Carcinogenesis 27:1018-23. 2006
  3. doi request reprint Validity of observation interval for synchronous hepatic metastases of colorectal cancer: changes in hepatic and extrahepatic metastatic foci
    Yasuhiro Shimizu
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Kanokoden 1 1, Chikusa ku, Nagoya, 464 8681, Japan
    Langenbecks Arch Surg 393:181-4. 2008
  4. ncbi request reprint Comparative analysis of intraperitoneal minimal free cancer cells between colorectal and gastric cancer patients using quantitative RT-PCR: possible reason for rare peritoneal recurrence in colorectal cancer
    Masayasu Hara
    Division of Oncological Pathology, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya, Aichi, 464 8681, Japan
    Clin Exp Metastasis 24:179-89. 2007
  5. ncbi request reprint Treatment strategy for synchronous metastases of colorectal cancer: is hepatic resection after an observation interval appropriate?
    Yasuhiro Shimizu
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Kanokoden 1 1, Chikusa ku, Nagoya, 464 8681, Japan
    Langenbecks Arch Surg 392:535-8. 2007
  6. ncbi request reprint Dietary risk factors for colon and rectal cancers: a comparative case-control study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    J Epidemiol 16:125-35. 2006
  7. doi request reprint Prolonged survival of patients with metastatic colorectal cancer following first-line oxaliplatin-based chemotherapy with molecular targeting agents and curative surgery
    Kohei Shitara
    Department of Clinical Oncology, Aichi Cancer Center Hospital, Chikusa ku, Nagoya, Japan
    Oncology 81:167-74. 2011
  8. doi request reprint Outcomes after hepatic and pulmonary metastasectomies compared with pulmonary metastasectomy alone in patients with colorectal cancer metastasis to liver and lungs
    Norifumi Hattori
    Department of Gastroenterological Surgery, Aichi Cancer Center, 1 1 Kanokoden, Chikusa ku, Nagoya, 464 8681, Japan
    World J Surg 37:1315-21. 2013
  9. doi request reprint Analysis of lymph node metastatic pattern according to the depth of in-growth in the muscularis propria in T2 rectal cancer for lateral lymph node dissection
    Koji Komori
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
    Dig Surg 28:352-9. 2011
  10. doi request reprint Detailed stratification of TNM stage III rectal cancer based on the presence/absence of extracapsular invasion of the metastatic lymph nodes
    Koji Komori
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Aichi, Japan
    Dis Colon Rectum 56:726-32. 2013

Detail Information

Publications39

  1. doi request reprint D3 Lymph Node Dissection in Right Hemicolectomy with a No-touch Isolation Technique in Patients With Colon Cancer
    Yukihide Kanemitsu
    Department of Gastroenterological Surgery, Aichi Cancer Center, Nagoya, Japan
    Dis Colon Rectum 56:815-24. 2013
    ..The role of lymph node dissection in the management of right-sided colon cancer remains controversial...
  2. ncbi request reprint A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in Japan
    Keitaro Matsuo
    Division of Epidemiology and Prevention, Aichi Cancer Center, Nagoya, Japan
    Carcinogenesis 27:1018-23. 2006
    ..38, 0.80-2.38). In conclusion, while we failed to find any significant association with the ALDH2 polymorphism itself, significant interaction between ALDH2 and ADH2 polymorphism was observed. Replication in the future study is warranted...
  3. doi request reprint Validity of observation interval for synchronous hepatic metastases of colorectal cancer: changes in hepatic and extrahepatic metastatic foci
    Yasuhiro Shimizu
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Kanokoden 1 1, Chikusa ku, Nagoya, 464 8681, Japan
    Langenbecks Arch Surg 393:181-4. 2008
    ..Our treatment policy has been to reevaluate the metastases at an interval of 3 months after colorectal resection and determine treatment strategy. We examined the validity of observation interval for synchronous hepatic metastases...
  4. ncbi request reprint Comparative analysis of intraperitoneal minimal free cancer cells between colorectal and gastric cancer patients using quantitative RT-PCR: possible reason for rare peritoneal recurrence in colorectal cancer
    Masayasu Hara
    Division of Oncological Pathology, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya, Aichi, 464 8681, Japan
    Clin Exp Metastasis 24:179-89. 2007
    ....
  5. ncbi request reprint Treatment strategy for synchronous metastases of colorectal cancer: is hepatic resection after an observation interval appropriate?
    Yasuhiro Shimizu
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Kanokoden 1 1, Chikusa ku, Nagoya, 464 8681, Japan
    Langenbecks Arch Surg 392:535-8. 2007
    ..Our treatment policy has been to conduct hepatic resection for the metastases at an interval of 3 months after colorectal resection. We examined the appropriateness of interval hepatic resection for synchronous hepatic metastasis...
  6. ncbi request reprint Dietary risk factors for colon and rectal cancers: a comparative case-control study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    J Epidemiol 16:125-35. 2006
    ..In Japan, the incidence rate of colon cancer has more rapidly increased than that of rectal cancer. The differential secular trends may be due to different dietary factors in the development of colon and rectal cancers...
  7. doi request reprint Prolonged survival of patients with metastatic colorectal cancer following first-line oxaliplatin-based chemotherapy with molecular targeting agents and curative surgery
    Kohei Shitara
    Department of Clinical Oncology, Aichi Cancer Center Hospital, Chikusa ku, Nagoya, Japan
    Oncology 81:167-74. 2011
    ..The ability of molecular targeting agents to improve overall survival (OS) in metastatic colorectal cancer (MCRC) patients who underwent oxaliplatin-based chemotherapy remains controversial...
  8. doi request reprint Outcomes after hepatic and pulmonary metastasectomies compared with pulmonary metastasectomy alone in patients with colorectal cancer metastasis to liver and lungs
    Norifumi Hattori
    Department of Gastroenterological Surgery, Aichi Cancer Center, 1 1 Kanokoden, Chikusa ku, Nagoya, 464 8681, Japan
    World J Surg 37:1315-21. 2013
    ..Therefore, we evaluated outcomes after pulmonary resection of colorectal metastases in patients with or without a history of curative hepatic metastasectomy...
  9. doi request reprint Analysis of lymph node metastatic pattern according to the depth of in-growth in the muscularis propria in T2 rectal cancer for lateral lymph node dissection
    Koji Komori
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
    Dig Surg 28:352-9. 2011
    ..The biological behavior of rectal cancers that invade the muscularis propria (pT2) has not been well studied. We retrospectively studied the pattern of lymph node metastases in patients with T2 rectal cancer...
  10. doi request reprint Detailed stratification of TNM stage III rectal cancer based on the presence/absence of extracapsular invasion of the metastatic lymph nodes
    Koji Komori
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Aichi, Japan
    Dis Colon Rectum 56:726-32. 2013
    ..However, the influence of extracapsular invasion in the metastatic lymph nodes on the prognosis in patients with stage III rectal cancer has not yet been investigated...
  11. doi request reprint Single-institute prospective trial of laparoscopy-assisted distal gastrectomy with systemic lymph node dissection for early gastric carcinoma
    Yoshinari Mochizuki
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
    Gastric Cancer 15:124-30. 2012
    ..We evaluate the feasibility of LAG with systemic lymph node dissection when participating surgeons have sufficient knowledge and experience to conduct open surgery for gastric cancer and basic laparoscopic skills...
  12. doi request reprint Decreased risk of colorectal cancer with the high natural killer cell activity NKG2D genotype in Japanese
    Hiroki Furue
    Central Laboratory and Radiation Biology, Aichi Cancer Center Research Institute, Nagoya, Japan
    Carcinogenesis 29:316-20. 2008
    ..Harboring the HNK1 is reported to reduce the overall cancer risk. To elucidate its impact on colorectal cancer (CRC), we conducted the present case-control study...
  13. ncbi request reprint Pathology studies of combined radical resection of seminal vesicle in the treatment of rectal cancer
    Koji Komori
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
    Int Surg 96:51-5. 2011
    ..Combined radical resection of the seminal vesicle in patients with rectal cancer ensures that the distance of the circumferential resection margin is sufficient to inhibit local recurrence...
  14. ncbi request reprint Clinicopathological study of poorly differentiated colorectal adenocarcinomas: comparison between solid-type and non-solid-type adenocarcinomas
    Koji Komori
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, 1 1, Kanokoden, Chikusa Nagoya, Aichi 464 8681, Japan
    Anticancer Res 31:3463-7. 2011
    ..We aimed to clarify the clinicopathological features of poorly differentiated colorectal adenocarcinomas and to define two subtypes of these adenocarcinomas...
  15. pmc Association between an 8q24 locus and the risk of colorectal cancer in Japanese
    Keitaro Matsuo
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    BMC Cancer 9:379. 2009
    ..Although the association with the identified loci was strong, information on its impact in combination with lifestyle factors is limited...
  16. ncbi request reprint Implantation metastasis along the percutaneous transhepatic biliary drainage sinus tract
    Yasuhiro Shimizu
    Department of Gastroenterological Surgery, Aichi Cancer Center, Nagoya, Japan
    Hepatogastroenterology 51:365-7. 2004
    ..If left in place, careful follow-up and awareness of this mode of tumor recurrence may lead to a timely resection, with preservation of a good quality of life and long-term survival...
  17. ncbi request reprint [Surgical treatment for colorectal liver metastases--results of multi-institute study for effects of radical hepatectomy]
    Kenzo Yasui
    Department of Gastroenterological Surgery, Aichi Cancer Center, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Gan To Kagaku Ryoho 31:690-4. 2004
    ..2% to 11.9% in each institute. This suggests that there could be a difference in diagnostic accuracy, surgical indication or timing of surgery for synchronous liver metastases in each institute...
  18. doi request reprint The relationship of lymph node evaluation and colorectal cancer survival after curative resection: a multi-institutional study
    Yukihide Kanemitsu
    Department of Gastroenterological Surgery, Aichi Cancer Center, Nagoya, Japan
    Ann Surg Oncol 19:2169-77. 2012
    ..However, to our knowledge, no comparative studies of esophagectomy and CRT have been reported in clinical T1bN0M0 esophageal cancer...
  19. ncbi request reprint Tumor necrosis in patients with TNM stage IV colorectal cancer without residual disease (R0 Status) is associated with a poor prognosis
    Koji Komori
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, 1 1, Kanokoden, Chikusa, Nagoya, Aichi 464 8681, Japan
    Anticancer Res 33:1099-105. 2013
    ..To examine the usefulness of the histopathological finding of tumor necrosis for stratifying TNM stage IV colorectal cancer in R0 status...
  20. ncbi request reprint Is "depth of submucosal invasion > or = 1,000 microm" an important predictive factor for lymph node metastases in early invasive colorectal cancer (pT1)?
    Koji Komori
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, 1 1, Kanokoden, Chikusa, Nagoya, Aichi 464 8681, Japan
    Hepatogastroenterology 57:1123-7. 2010
    ....
  21. doi request reprint Prediction of residual disease or distant metastasis after resection of locally recurrent rectal cancer
    Yukihide Kanemitsu
    Department of Gastroenterological Surgery, Aichi Cancer Center, Nagoya, Japan
    Dis Colon Rectum 53:779-89. 2010
    ....
  22. ncbi request reprint [Staging and indications for hepatectomy in hepatic metastases of colorectal cancer]
    Tomoyuki Kato
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
    Nihon Geka Gakkai Zasshi 107:104-8. 2006
    ..Unilobar or bilobar disease with multiple lesions is not a significant prognostic factor...
  23. ncbi request reprint Therapeutic results for hepatic metastasis of colorectal cancer with special reference to effectiveness of hepatectomy: analysis of prognostic factors for 763 cases recorded at 18 institutions
    Tomoyuki Kato
    Department of Gastroenterological Surgery, Aichi Cancer Center, Nagoya, Japan
    Dis Colon Rectum 46:S22-31. 2003
    ..Factors affecting treatment prognosis and therapeutic results for hepatic metastasis of colorectal cancer were investigated...
  24. ncbi request reprint Treatment and risk factors for recurrence after curative resection of gastrointestinal stromal tumors of the stomach
    Yoshinari Mochizuki
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, 1 1, Kanokoden, Chikusa ku, 464 8681 Nagoya, Japan
    World J Surg 28:870-5. 2004
    ..0051). In conclusion, surgical resection may be indicated whenever a recurrent GIST is considered resectable. A high MIB-1 PI was identified as an independent indicator of risk for recurrent disease following curative surgery...
  25. ncbi request reprint One-carbon metabolism related gene polymorphisms interact with alcohol drinking to influence the risk of colorectal cancer in Japan
    Keitaro Matsuo
    Division of Epidemiology and Prevention, Aichi Cancer Center, Nagoya 464 8681, Japan
    Carcinogenesis 26:2164-71. 2005
    ..In conclusion, we found consistently significant interactions between one-carbon metabolism-related polymorphisms and alcohol drinking...
  26. ncbi request reprint Survival after curative resection for mucinous adenocarcinoma of the colorectum
    Yukihide Kanemitsu
    Department of Gastroenterological Surgery, The Aichi Cancer Center, Kanokoden, Nagoya, Japan
    Dis Colon Rectum 46:160-7. 2003
    ..The purpose of this study was to clarify whether the mucin-producing histologic type of carcinoma is associated with a worse prognosis than nonmucinous, differentiated colorectal adenocarcinoma for patients who undergo curative surgery...
  27. pmc Distinct profiles of epigenetic evolution between colorectal cancers with and without metastasis
    Hai xing Ju
    Division of Molecular Oncology, Aichi Cancer Center Research Institute, Nagoya, Japan
    Am J Pathol 178:1835-46. 2011
    ..In addition, most methylation status in stage IV CRCs seems to be established before metastasis...
  28. doi request reprint Validation of a nomogram for predicting overall survival after resection of pulmonary metastases from colorectal cancer at a single center
    Yukihide Kanemitsu
    Department of Gastroenterological Surgery, Aichi Cancer Center, 1 1 Kanokoden, Chikusa ku, Nagoya, 464 8681, Japan
    World J Surg 34:2973-8. 2010
    ....
  29. doi request reprint Negative serum carcinoembryonic antigen has insufficient accuracy for excluding recurrence from patients with Dukes C colorectal cancer: analysis with likelihood ratio and posttest probability in a follow-up study
    Masayasu Hara
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, 1 1 Kanokoden, Chikusa ku, Nagoya, Japan
    Dis Colon Rectum 51:1675-80. 2008
    ..This study was designed to determine the efficacy of carcinoembryonic antigen (CEA) monitoring for screening patients with colorectal cancer by using posttest probability of recurrence...
  30. doi request reprint A nomogram for predicting the probability of carcinoma in patients with intraductal papillary-mucinous neoplasm
    Yasuhiro Shimizu
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Kanokoden 1 1, Chikusa ku, Nagoya, 464 8681, Japan
    World J Surg 34:2932-8. 2010
    ..The objective of the present study was to use clinical and laboratory data to develop a model for predicting the presence of carcinoma in patients with intraductal papillary mucinous neoplasm (IPMN)...
  31. ncbi request reprint Possible oncogenesis of mucinous cystic tumors of the pancreas lacking ovarian-like stroma
    Yasuhiro Shimizu
    Department of Gastroenterological Surgery, Aichi Cancer Center, Nagoya, Japan
    Pancreatology 2:413-20. 2002
    ..MCTs with ovarian-like stroma (MCTs-OLS+; n = 6) and those lacking ovarian-like stroma (MCTs-OLS-; n = 4) were compared to elucidate the oncogenesis of MCT without OLS...
  32. doi request reprint A randomized phase II/III trial comparing hepatectomy followed by mFOLFOX6 with hepatectomy alone as treatment for liver metastasis from colorectal cancer: Japan Clinical Oncology Group Study JCOG0603
    Yukihide Kanemitsu
    Department of Gastroenterological Surgery, Aichi Cancer Center, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Jpn J Clin Oncol 39:406-9. 2009
    ..The primary endpoint is treatment compliance at nine courses of mFOLFOX6 regimen in Phase II and disease-free survival in Phase III. The secondary endpoints are overall survival, incidence of adverse events and patterns of recurrence...
  33. ncbi request reprint Practical prognostic index for patients with metastatic pancreatic cancer treated with gemcitabine
    Akira Sawaki
    Department of Gastroenterology, Aichi Cancer Center Hospital, Chikusa ku, Nagoya, Japan
    J Gastroenterol Hepatol 23:1292-7. 2008
    ..The aim of this study was to identify factors that predict treatment outcome in patients with metastatic pancreatic cancer treated with gemcitabine, and then to use these factors to develop a practical prognostic index...
  34. doi request reprint Prognostic models for predicting death after hepatectomy in individuals with hepatic metastases from colorectal cancer
    Yukihide Kanemitsu
    Department of Gastroenterological Surgery, Aichi Cancer Center, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    World J Surg 32:1097-107. 2008
    ..Establishing the prognosis of patients with hepatic metastases from colorectal cancer is an important part of their evaluation and treatment...
  35. ncbi request reprint Increased risk of colorectal cancer due to interactions between meat consumption and the CD36 gene A52C polymorphism among Japanese
    Kiyonori Kuriki
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Nutr Cancer 51:170-7. 2005
    ..03 (95% CI=1.12-7.90). Our findings suggest that interactions between moderate-high meat consumption and the CD36 gene A52C polymorphism may increase the risk of colorectal cancer...
  36. ncbi request reprint [Actual standards and controversies in colorectal cancer surgery]
    Tomoyuki Kato
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
    Nihon Geka Gakkai Zasshi 104:422-6. 2003
    ..Extended lateral lymph node dissection is indicated for patients with lower rectal cancer invading the muscularis propria or deeper. In stage IV and recurrent cancer, surgical resection is recommended if it appears to offer cure...
  37. ncbi request reprint [Pseudomyxoma peritonei--diagnosis and treatment]
    Yukihide Kanemitsu
    Department of Gastroenterological Surgery, Aichi Cancer Center, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Gan To Kagaku Ryoho 30:614-8. 2003
    ..This disease is a malignancy that, even after excision of the metastatic areas, has a poor prognosis, since no effective therapy has yet been established besides debulking surgery...
  38. ncbi request reprint A two-step method for marking polypectomy sites in the colon and rectum
    Akira Sawaki
    Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan
    Gastrointest Endosc 57:735-7. 2003
    ..A new two-step method for marking polypectomy sites for identification during laparoscopic and open operations is described...
  39. ncbi request reprint Quantitative detection of disseminated cancer cells in the greater omentum of gastric carcinoma patients with real-time RT-PCR: a comparison with peritoneal lavage cytology
    Yasuhiro Kodera
    Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
    Gastric Cancer 5:69-76. 2002
    ..It may be beneficial to explore, by the same method, a sample of the omentum, which is known to harbor cancer cells before the establishment of gross peritoneal metastasis...