S Iyoda

Summary

Affiliation: National Institute of Infectious Diseases
Country: Japan

Publications

  1. pmc The hemolytic and cytolytic activities of Serratia marcescens phospholipase A (PhlA) depend on lysophospholipid production by PhlA
    Ken Shimuta
    Department of Bacteriology I, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    BMC Microbiol 9:261. 2009
  2. ncbi request reprint A flagellar gene fliZ regulates the expression of invasion genes and virulence phenotype in Salmonella enterica serovar Typhimurium
    S Iyoda
    Department of Bacteriology, National Institute of Infectious Diseases, Tokyo, Toyama 1 23 1 Shinjuku ku, 162 8640, Japan
    Microb Pathog 30:81-90. 2001
  3. pmc A new immunoglobulin-binding protein, EibG, is responsible for the chain-like adhesion phenotype of locus of enterocyte effacement-negative, shiga toxin-producing Escherichia coli
    Yan Lu
    Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    Infect Immun 74:5747-55. 2006
  4. pmc The GrlR-GrlA regulatory system coordinately controls the expression of flagellar and LEE-encoded type III protein secretion systems in enterohemorrhagic Escherichia coli
    Sunao Iyoda
    Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    J Bacteriol 188:5682-92. 2006
  5. pmc ClpXP protease controls expression of the type III protein secretion system through regulation of RpoS and GrlR levels in enterohemorrhagic Escherichia coli
    Sunao Iyoda
    Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    J Bacteriol 187:4086-94. 2005
  6. pmc Coordinate control of the locus of enterocyte effacement and enterohemolysin genes by multiple common virulence regulators in enterohemorrhagic Escherichia coli
    Sunao Iyoda
    Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    Infect Immun 79:4628-37. 2011
  7. ncbi request reprint Positive effects of multiple pch genes on expression of the locus of enterocyte effacement genes and adherence of enterohaemorrhagic Escherichia coli O157 : H7 to HEp-2 cells
    Sunao Iyoda
    Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    Microbiology 150:2357-571. 2004
  8. pmc Transcription of the ehx enterohemolysin gene is positively regulated by GrlA, a global regulator encoded within the locus of enterocyte effacement in enterohemorrhagic Escherichia coli
    Takehito Saitoh
    Department of Bacteriology, Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo 162 8640, Japan
    J Bacteriol 190:4822-30. 2008
  9. doi request reprint LrhA positively controls the expression of the locus of enterocyte effacement genes in enterohemorrhagic Escherichia coli by differential regulation of their master regulators PchA and PchB
    Naoko Honda
    Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    Mol Microbiol 74:1393-41. 2009
  10. ncbi request reprint [PulseNet Japan: surveillance system for the early detection of diffuse outbreak based on the molecular epidemiological method]
    Haruo Watanabe
    Department of Bacteriology, National Institute of Infectious Diseases, Shinjuku, Tokyo 162 8640, Japan
    Kansenshogaku Zasshi 76:842-8. 2002

Collaborators

Detail Information

Publications21

  1. pmc The hemolytic and cytolytic activities of Serratia marcescens phospholipase A (PhlA) depend on lysophospholipid production by PhlA
    Ken Shimuta
    Department of Bacteriology I, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    BMC Microbiol 9:261. 2009
    ..There have been few studies of the virulence factors of this bacterium. The only S. marcescens hemolytic and cytotoxic factor reported, thus far, is the hemolysin ShlA...
  2. ncbi request reprint A flagellar gene fliZ regulates the expression of invasion genes and virulence phenotype in Salmonella enterica serovar Typhimurium
    S Iyoda
    Department of Bacteriology, National Institute of Infectious Diseases, Tokyo, Toyama 1 23 1 Shinjuku ku, 162 8640, Japan
    Microb Pathog 30:81-90. 2001
    ..These results indicate that the fliZ gene product positively regulates the invasion genes and is necessary for expression of full virulence...
  3. pmc A new immunoglobulin-binding protein, EibG, is responsible for the chain-like adhesion phenotype of locus of enterocyte effacement-negative, shiga toxin-producing Escherichia coli
    Yan Lu
    Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    Infect Immun 74:5747-55. 2006
    ..These results indicate that EibG acts as an IgG Fc- and IgA-binding protein, as well as an adhesin of LEE-negative STEC...
  4. pmc The GrlR-GrlA regulatory system coordinately controls the expression of flagellar and LEE-encoded type III protein secretion systems in enterohemorrhagic Escherichia coli
    Sunao Iyoda
    Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    J Bacteriol 188:5682-92. 2006
    ..The fact that an EHEC strain constitutively expressing FlhD/FlhC cannot adhere to HeLa cells leads us to hypothesize that GrlA-dependent repression of the flagellar regulon is important for efficient cell adhesion of EHEC to host cells...
  5. pmc ClpXP protease controls expression of the type III protein secretion system through regulation of RpoS and GrlR levels in enterohemorrhagic Escherichia coli
    Sunao Iyoda
    Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    J Bacteriol 187:4086-94. 2005
    ..These results suggest that ClpXP controls expression of LEE through the regulation of RpoS and GrlR levels in EHEC...
  6. pmc Coordinate control of the locus of enterocyte effacement and enterohemolysin genes by multiple common virulence regulators in enterohemorrhagic Escherichia coli
    Sunao Iyoda
    Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    Infect Immun 79:4628-37. 2011
    ..Together, these results indicate that transcription of ehx is positively regulated by Ler, GrlA, and LrhA, which all act as positive regulators for LEE expression...
  7. ncbi request reprint Positive effects of multiple pch genes on expression of the locus of enterocyte effacement genes and adherence of enterohaemorrhagic Escherichia coli O157 : H7 to HEp-2 cells
    Sunao Iyoda
    Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    Microbiology 150:2357-571. 2004
    ..Introduction of a multicopy plasmid carrying each pchA/B/C gene significantly induced microcolony formation by EHEC O157 on HEp-2 cells. These results suggest that the pchABC genes are necessary for full virulence of EHEC O157...
  8. pmc Transcription of the ehx enterohemolysin gene is positively regulated by GrlA, a global regulator encoded within the locus of enterocyte effacement in enterohemorrhagic Escherichia coli
    Takehito Saitoh
    Department of Bacteriology, Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo 162 8640, Japan
    J Bacteriol 190:4822-30. 2008
    ..These results together suggest that GrlA acts as a positive regulator for the ehx transcription in EHEC...
  9. doi request reprint LrhA positively controls the expression of the locus of enterocyte effacement genes in enterohemorrhagic Escherichia coli by differential regulation of their master regulators PchA and PchB
    Naoko Honda
    Department of Bacteriology, National Institute of Infectious Diseases, Toyama 1 23 1, Shinjuku ku, Tokyo 162 8640, Japan
    Mol Microbiol 74:1393-41. 2009
    ..Purified His(6)-LrhA protein differentially bound to the regulatory regions of pchA/B, suggesting that direct regulation of pchA and pchB genes by LrhA in turn controls the expression of LEE genes...
  10. ncbi request reprint [PulseNet Japan: surveillance system for the early detection of diffuse outbreak based on the molecular epidemiological method]
    Haruo Watanabe
    Department of Bacteriology, National Institute of Infectious Diseases, Shinjuku, Tokyo 162 8640, Japan
    Kansenshogaku Zasshi 76:842-8. 2002
    ..A PFGE network, PulseNet Japan, is now under construction among National Institute of Infectious Diseases, local Health Institutes and Ministry of Health, Labour and Welfare...
  11. ncbi request reprint High genomic diversity of enterohemorrhagic Escherichia coli isolates in Japan and its applicability for the detection of diffuse outbreak
    Jun Terajima
    Department of Bacteriology, National Institute of Infectious Diseases, Tokyo 162 8640, Japan
    Jpn J Infect Dis 55:19-22. 2002
    ..Based on the diversity of genotypes among the isolates of enterohemorrhagic E. coli O157:H7/- in Japan, we suggest the presence of a few other possible diffuse outbreaks due to the organisms, showing indistinguishable genotypes...
  12. doi request reprint New system for multilocus variable-number tandem-repeat analysis of the enterohemorrhagic Escherichia coli strains belonging to three major serogroups: O157, O26, and O111
    Hidemasa Izumiya
    Department of Bacteriology I, National Institute of Infectious Diseases, Shinjuku ku, Tokyo, Japan
    Microbiol Immunol 54:569-77. 2010
    ..Because EHEC strains of three major serogroups can be rapidly analyzed on a single platform with our expanded MLVA system, this system could be widely used in molecular epidemiological studies of EHEC infections...
  13. ncbi request reprint Effectiveness of pulsed-field gel electrophoresis for the early detection of diffuse outbreaks due to Shiga toxin-producing Escherichia coli in Japan
    Jun Terajima
    Department of Bacteriology, National Institute of Infectious Diseases, Tokyo, Japan
    Foodborne Pathog Dis 3:68-73. 2006
    ....
  14. ncbi request reprint Molecular typing methods for STEC
    Haruo Watanabe
    Department of Bacteriology, National Institute of Infectious Diseases, Tokyo, Japan
    Methods Mol Med 73:55-65. 2003
  15. ncbi request reprint Molecular characterization of enterohemorrhagic Escherichia coli O157:H7 isolates dispersed across Japan by pulsed-field gel electrophoresis and multiple-locus variable-number tandem repeat analysis
    Yingxin Pei
    Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, China
    Jpn J Infect Dis 61:58-64. 2008
    ..Therefore, compared to PFGE, MLVA showed greater discriminatory power with respect to analysis of the isolates in this study...
  16. ncbi request reprint Identification of enterohemorrhagic Escherichia coli O157-Specific DNA sequence obtained from amplified fragment length polymorphism analysis
    Akihiko Tokunaga
    Department of Bioresource Science, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo, Japan
    Microbiol Immunol 51:883-8. 2007
    ....
  17. pmc Distribution of putative adhesins in different seropathotypes of Shiga toxin-producing Escherichia coli
    Claudia Toma
    Division of Bacterial Pathogenesis, Department of Microbiology, Graduate School of Medicine, University of the Ryukyus, Nishihara, Okinawa 903 0215, Japan
    J Clin Microbiol 42:4937-46. 2004
    ..The wide distribution of iha in STEC strains suggested that it could be a candidate for vaccine development...
  18. ncbi request reprint The long polar fimbriae genes identified in Shiga toxin-producing Escherichia coli are present in other diarrheagenic E. coli and in the standard E. coli collection of reference (ECOR) strains
    Claudia Toma
    Division of Bacterial Pathogenesis, Department of Microbiology, Graduate School of Medicine, University of the Ryukyus, Nishihara, Okinawa 903 0215, Japan
    Res Microbiol 157:153-61. 2006
    ..This study showed that the lpfA genes identified in the genome of STEC strains are not specific to this category. Our results suggest that there is a relationship between the lpfA variant and the phylogenetic group...
  19. ncbi request reprint Detection and characterization of Shiga toxin-producing Escherichia coli in captive non-domestic mammals
    Gerardo A Leotta
    Servicio Fisiopatogenia, Instituto Nacional de Enfermedades Infecciosas ANLIS Dr Carlos G Malbran, 1281 Buenos Aires, Argentina
    Vet Microbiol 118:151-7. 2006
    ..This is the first work developed with zoological mammals and STEC in Argentina...
  20. ncbi request reprint Spontaneous recombination between homologous prophage regions causes large-scale inversions within the Escherichia coli O157:H7 chromosome
    Atsushi Iguchi
    Department of Bioscience, Graduate School of Science and Technology, Kobe University, 1 1 Rokko dai, Kobe, Hyogo, 657 8501, Japan
    Gene 372:199-207. 2006
    ..coli O157:H7 chromosome, where recombination between the prophage regions results not only in the large chromosomal inversions but might also in generation of chimeric phages...
  21. ncbi request reprint O side chain deficiency enhances sensitivity of Escherichia coli to Shiga toxin 2-converting bacteriophages
    Atsushi Iguchi
    Department of Bioscience, Graduate School of Science and Technology, Kobe University, Rokko dai 1 1, Kobe, 657 8501, Japan
    Curr Microbiol 54:14-9. 2007
    ..The evidence suggests that an O side chain deficiency leads to the creation of new pathotypes of Shiga toxin-producing E. coli (STEC) within the intestinal microflora...