Motoki Iwasaki

Summary

Affiliation: National Cancer Center
Country: Japan

Publications

  1. ncbi request reprint Validity of a self-administered food frequency questionnaire in the estimation of heterocyclic aromatic amines
    Motoki Iwasaki
    Division of Epidemiology, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Cancer Causes Control 25:1015-28. 2014
  2. pmc Validity of a self-administered food frequency questionnaire for middle-aged urban cancer screenees: comparison with 4-day weighed dietary records
    Ribeka Takachi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Epidemiol 21:447-58. 2011
  3. pmc Dietary isoflavone and the risk of colorectal adenoma: a case-control study in Japan
    M Akhter
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Br J Cancer 100:1812-6. 2009
  4. pmc Association of postmenopausal endogenous sex hormones with global methylation level of leukocyte DNA among Japanese women
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, Tsukiji, Chuo Ku, Tokyo, Japan
    BMC Cancer 12:323. 2012
  5. pmc Green tea drinking and subsequent risk of breast cancer in a population-based cohort of Japanese women
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Breast Cancer Res 12:R88. 2010
  6. doi request reprint Dietary isoflavone intake, polymorphisms in the CYP17, CYP19, 17beta-HSD1, and SHBG genes, and risk of breast cancer in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Nutr Cancer 62:466-75. 2010
  7. doi request reprint Isoflavone, polymorphisms in estrogen receptor genes and breast cancer risk in case-control studies in Japanese, Japanese Brazilians and non-Japanese Brazilians
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Cancer Sci 100:927-33. 2009
  8. ncbi request reprint Plasma organochlorine levels and subsequent risk of breast cancer among Japanese women: a nested case-control study
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Sci Total Environ 402:176-83. 2008
  9. doi request reprint Plasma tea polyphenol levels and subsequent risk of breast cancer among Japanese women: a nested case-control study
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Breast Cancer Res Treat 124:827-34. 2010
  10. ncbi request reprint Food frequency questionnaire is a valid tool in the nutritional assessment of Brazilian women of diverse ethnicity
    Junko Ishihara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Asia Pac J Clin Nutr 18:76-80. 2009

Collaborators

Detail Information

Publications100

  1. ncbi request reprint Validity of a self-administered food frequency questionnaire in the estimation of heterocyclic aromatic amines
    Motoki Iwasaki
    Division of Epidemiology, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Cancer Causes Control 25:1015-28. 2014
    ..This study primarily aimed to evaluate the validity of a food frequency questionnaire (FFQ) in estimating HAA intake, using 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) level in human hair as the reference method...
  2. pmc Validity of a self-administered food frequency questionnaire for middle-aged urban cancer screenees: comparison with 4-day weighed dietary records
    Ribeka Takachi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Epidemiol 21:447-58. 2011
    ..We examined the validity of ranking individuals according to level of dietary consumption, as estimated by this FFQ, among an urban population in Japan...
  3. pmc Dietary isoflavone and the risk of colorectal adenoma: a case-control study in Japan
    M Akhter
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Br J Cancer 100:1812-6. 2009
    ..The observed ceiling effect associated with higher isoflavone intake suggests that a lower intake of dietary isoflavone might be associated with an increased risk of colorectal adenoma in Japanese populations...
  4. pmc Association of postmenopausal endogenous sex hormones with global methylation level of leukocyte DNA among Japanese women
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, Tsukiji, Chuo Ku, Tokyo, Japan
    BMC Cancer 12:323. 2012
    ..Here, we examined whether postmenopausal endogenous sex hormones were associated with the global methylation level of leukocyte DNA...
  5. pmc Green tea drinking and subsequent risk of breast cancer in a population-based cohort of Japanese women
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Breast Cancer Res 12:R88. 2010
    ....
  6. doi request reprint Dietary isoflavone intake, polymorphisms in the CYP17, CYP19, 17beta-HSD1, and SHBG genes, and risk of breast cancer in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Nutr Cancer 62:466-75. 2010
    ..06-0.77). We found no remarkable difference for the rs743572 and rs10046 polymorphisms. Our findings suggest that polymorphisms in the 17beta-HSD1 and SHBG genes may modify the association between isoflavone intake and breast cancer risk...
  7. doi request reprint Isoflavone, polymorphisms in estrogen receptor genes and breast cancer risk in case-control studies in Japanese, Japanese Brazilians and non-Japanese Brazilians
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Cancer Sci 100:927-33. 2009
    ..21, respectively). We found no remarkable difference for the other four polymorphisms. Our findings suggest that polymorphisms in the estrogen receptor beta gene may modify the association between isoflavone intake and breast cancer risk...
  8. ncbi request reprint Plasma organochlorine levels and subsequent risk of breast cancer among Japanese women: a nested case-control study
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Sci Total Environ 402:176-83. 2008
    ..Our data do not support the hypothesis that plasma levels of p,p'-DDT, p,p'-DDE, HCB, and beta-HCH are associated with an overall increased risk of breast cancer among Japanese women...
  9. doi request reprint Plasma tea polyphenol levels and subsequent risk of breast cancer among Japanese women: a nested case-control study
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Breast Cancer Res Treat 124:827-34. 2010
    ..This nested case-control study found no overall association between plasma tea polyphenols and the risk of breast cancer in Japan...
  10. ncbi request reprint Food frequency questionnaire is a valid tool in the nutritional assessment of Brazilian women of diverse ethnicity
    Junko Ishihara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Asia Pac J Clin Nutr 18:76-80. 2009
    ..In conclusion, validity of the FFQ for estimation of the intake of selected nutrients among Brazilian women with varied ethnic background was moderately high...
  11. pmc Comparison of postmenopausal endogenous sex hormones among Japanese, Japanese Brazilians, and non-Japanese Brazilians
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    BMC Med 9:16. 2011
    ....
  12. doi request reprint Risk factors for breast cancer: epidemiological evidence from Japanese studies
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Sci 102:1607-14. 2011
    ..In conclusion, based on current knowledge, primary prevention according to individual lifestyle modification should focus on alcohol intake, weight control, physical activity, and tobacco smoking...
  13. doi request reprint Dietary isoflavone intake and breast cancer risk in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Breast Cancer Res Treat 116:401-11. 2009
    ..In addition, women may benefit from risk reduction if they consume at least moderate amounts of isoflavones...
  14. doi request reprint Fragment c gamma receptor gene polymorphisms and breast cancer risk in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Breast Cancer Res Treat 126:497-505. 2011
    ..68 (95% CI 0.37-1.27). In conclusion, our findings suggest that ADCC might not play a major role in the etiology of breast cancer...
  15. ncbi request reprint Dietary intake of folate, vitamin B2, vitamin B6, vitamin B12, genetic polymorphism of related enzymes, and risk of breast cancer: a case-control study in Japan
    Enbo Ma
    National Cancer Center, Tokyo, Japan
    Nutr Cancer 61:447-56. 2009
    ..We conclude that dietary intake of folate and related B vitamins and genotypes of MTHFR or MTR have no overall association with breast cancer risk in Japanese women...
  16. doi request reprint Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of stomach cancer: a hospital-based case-control study in Japan
    Minatsu Kobayashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Gastric Cancer 12:198-205. 2009
    ..We conducted a case-control study to investigate the association between HCA intake and stomach cancer risk. We also investigated the possible effect of genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 on stomach cancer...
  17. ncbi request reprint Female reproductive factors and the risk of gastric cancer in a large-scale population-based cohort study in Japan (JPHC study)
    Christina Persson
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 17:345-53. 2008
    ..Although early estrogen exposure may have some protective effect, female reproductive factors may have no substantial influence on gastric cancer development...
  18. ncbi request reprint Daily total physical activity level and total cancer risk in men and women: results from a large-scale population-based cohort study in Japan
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Epidemiol 168:391-403. 2008
    ..By site, decreased risks were observed for cancers of the colon, liver, and pancreas in men and for cancer of the stomach in women. Increased daily physical activity may be beneficial in preventing cancer in a relatively lean population...
  19. doi request reprint Combined impact of five lifestyle factors and subsequent risk of cancer: the Japan Public Health Center Study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Prev Med 54:112-6. 2012
    ..To evaluate whether 5 combined healthy lifestyle factors (not smoking, moderate drinking, eating minimum salt-preserved foods, being physically active, and having appropriate body mass index) are associated with reduced risk of cancer...
  20. doi request reprint Alcohol and risk of lung cancer among Japanese men: data from a large-scale population-based cohort study, the JPHC study
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Causes Control 19:1095-102. 2008
    ..Here, we investigated the association between alcohol consumption and lung cancer incidence...
  21. doi request reprint Association of dietary and genetic factors related to one-carbon metabolism with global methylation level of leukocyte DNA
    Hiroe Ono
    Division of Genetics, National Cancer Center Research Institute, Tokyo, Japan
    Cancer Sci 103:2159-64. 2012
    ..We found that higher folate intake was significantly associated with a lower level of global methylation of leukocyte DNA in a group of healthy Japanese females...
  22. doi request reprint 10-Year risk of colorectal cancer: development and validation of a prediction model in middle-aged Japanese men
    Enbo Ma
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Epidemiol 34:534-41. 2010
    ..As fewer studies on cancer risk prediction were seen so far, we initially developed an assessment tool with synthesizing key information from a variety of CRC risk factors through a large population-based cohort study...
  23. doi request reprint p53 expression in tumor-stromal fibroblasts is closely associated with the nodal metastasis and outcome of patients with invasive ductal carcinoma who received neoadjuvant therapy
    Takahiro Hasebe
    Clinical Trials and Practice Support Division, Pathology Consultation Service, Center for Cancer Control and Information Services, National Cancer Center, Tokyo 104 0045, Japan
    Hum Pathol 41:262-70. 2010
    ....
  24. ncbi request reprint Folate, vitamin B6, vitamin B12, and vitamin B2 intake, genetic polymorphisms of related enzymes, and risk of colorectal cancer in a hospital-based case-control study in Japan
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tsukjii, Tokyo
    Nutr Cancer 53:42-50. 2005
    ..02) with colorectal cancer, although the other polymorphisms did not interact with any nutrient intake. In conclusion, the study did not support the existing hypothesis of gene-nutrient interaction in colorectal carcinogenesis...
  25. ncbi request reprint Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population
    Shinobu Ikeda
    Department of Molecular Epidemiology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan
    Am J Gastroenterol 103:1476-87. 2008
    ..To investigate the association between polymorphisms and gastrointestinal (gastric and colorectal) cancer, we performed a hospital-based case-control study in Japan...
  26. doi request reprint Long-term dietary cadmium intake and cancer incidence
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Epidemiology 23:368-76. 2012
    ..However, data from general populations are sparse. We prospectively examined the association between cadmium exposure and incidence of cancer in a Japanese population with a relatively high dietary intake of cadmium...
  27. ncbi request reprint Fruit and vegetable consumption and squamous cell carcinoma of the esophagus in Japan: the JPHC study
    Taiki Yamaji
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 123:1935-40. 2008
    ..Finally, cruciferous vegetables deserve further investigation as foods possibly effective in the prevention of esophageal SCC...
  28. doi request reprint Isoflavone consumption and subsequent risk of hepatocellular carcinoma in a population-based prospective cohort of Japanese men and women
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 124:1644-9. 2009
    ..Women with hepatitis virus infection may be advised to abstain from isoflavone consumption. Further studies are warranted to confirm these findings...
  29. ncbi request reprint Body mass index and subsequent risk of kidney cancer: a prospective cohort study in Japan
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 20:466-72. 2010
    ..Herein, we investigate the association between body mass index (BMI) and kidney cancer risk in Japanese persons, a relatively lean population...
  30. doi request reprint Dairy product, saturated fatty acid, and calcium intake and prostate cancer in a prospective cohort of Japanese men
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 17:930-7. 2008
    ..62 (1.15-2.29) and 1.53 (1.07-2.20), respectively. In conclusion, our results suggest that the intake of dairy products may be associated with an increased risk of prostate cancer...
  31. doi request reprint Body weight at age 20 years, subsequent weight change and breast cancer risk defined by estrogen and progesterone receptor status--the Japan public health center-based prospective study
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 129:1214-24. 2011
    ..50-3.34)]. Low BMI at age 20 years was substantially associated with an increased risk of breast cancer. In contrast, high recent BMI and subsequent BMI gain from age 20 were associated with increased risk of postmenopausal ER+PR+ tumors...
  32. doi request reprint Plasma isoflavone concentrations are not associated with gastric cancer risk among Japanese men and women
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Nutr 143:1293-8. 2013
    ..We found no association of plasma isoflavone concentrations with gastric cancer risk. Our data support the previously observed null association between isoflavone intake and gastric cancer risk...
  33. ncbi request reprint Zinc and heme iron intakes and risk of colorectal cancer: a population-based prospective cohort study in Japan
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Clin Nutr 96:864-73. 2012
    ..However, all of the studies on the association between zinc and heme iron intakes and colorectal cancer have been conducted in Western populations...
  34. ncbi request reprint Consumption of n-3 fatty acids and fish reduces risk of hepatocellular carcinoma
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tsukiji, Chuo ku Tokyo, Japan
    Gastroenterology 142:1468-75. 2012
    ..Although consumption of fish and n-3 PUFA has been reported to protect against the development of some types of cancer, little is known about its association with hepatocellular carcinoma (HCC)...
  35. doi request reprint Isoflavone intake and risk of gastric cancer: a population-based prospective cohort study in Japan
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Clin Nutr 95:147-54. 2012
    ..The association with gastric cancer might differ between isoflavones and soy foods, and research on the effects of isoflavone intake alone on gastric cancer is needed...
  36. pmc Dietary intake of folate, vitamin B6, and vitamin B12, genetic polymorphism of related enzymes, and risk of breast cancer: a case-control study in Brazilian women
    Enbo Ma
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    BMC Cancer 9:122. 2009
    ..However, the association between B vitamin intake and breast cancer risk in Brazilian women in particular has not yet been investigated...
  37. pmc Use of vitamin supplements and risk of total cancer and cardiovascular disease among the Japanese general population: a population-based survey
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo 104 0045, Japan
    BMC Public Health 11:540. 2011
    ..We examined whether vitamin supplement use patterns affect cancer and CVD risk in a population-based cohort study in Japan...
  38. doi request reprint Coffee, green tea, and caffeine consumption and subsequent risk of bladder cancer in relation to smoking status: a prospective study in Japan
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer Sci 100:294-91. 2009
    ..15–3.66), respectively. In conclusion, cigarette smoking was confirmed as a risk factor for bladder cancer. Coffee and caffeine may be associated with an increased bladder cancer risk in never or former smokers among Japanese men...
  39. doi request reprint Serum aminotransferase level and the risk of hepatocellular carcinoma: a population-based cohort study in Japan
    Seiji Ishiguro
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 18:26-32. 2009
    ..This finding indicates that ALT level is a good independent determinant of the need for intervention. Clinical application of these findings may help decrease HCC-associated mortality in hepatitis virus-endemic regions...
  40. doi request reprint Leisure-time physical activity and breast cancer risk defined by estrogen and progesterone receptor status--the Japan Public Health Center-based Prospective Study
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo, 104 0045, Japan
    Prev Med 52:227-33. 2011
    ..The study aims to investigate the association between leisure-time physical activity and breast cancer risk in consideration of tumor estrogen-receptor/progesterone-receptor status...
  41. doi request reprint Plasma isoflavone level and subsequent risk of breast cancer among Japanese women: a nested case-control study from the Japan Public Health Center-based prospective study group
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    J Clin Oncol 26:1677-83. 2008
    ..Nevertheless, no prospective study from Asia has assessed blood or urine levels as biomarkers of isoflavone intake...
  42. doi request reprint Methionine synthase A2756G polymorphism interacts with alcohol and folate intake to influence the risk of colorectal adenoma
    Taiki Yamaji
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Epidemiol Biomarkers Prev 18:267-74. 2009
    ..Our findings add to increasing evidence that DNA methylation plays an important role even at an early stage of colorectal carcinogenesis...
  43. ncbi request reprint Coping behaviors and suicide in the middle-aged and older Japanese general population: the Japan Public Health Center-based Prospective Study
    Thomas Svensson
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan Department of Neuropsychiatry, Keio University School of Medicine, Shinjuku ku, Tokyo, Japan
    Ann Epidemiol 24:199-205. 2014
    ..Cross-sectional studies have shown an association between different coping styles and suicidal behavior. It is unknown whether there is any prospective association between coping behaviors and suicide in the general population...
  44. ncbi request reprint Impact of five modifiable lifestyle habits on the probability of cancer occurrence in a Japanese population-based cohort: results from the JPHC study
    Hadrien Charvat
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Prev Med 57:685-9. 2013
    ..The present work aims to provide 10-year estimates of the probability of cancer occurrence in the Japanese population based on age, sex, and the pattern of adherence to five healthy lifestyle habits...
  45. doi request reprint Effect of alcohol consumption, cigarette smoking and flushing response on esophageal cancer risk: a population-based cohort study (JPHC study)
    Seiji Ishiguro
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Lett 275:240-6. 2009
    ..10-5.51). Strong effect modification was detected in heavy smokers. Our results suggest that heavy alcohol consumption together with heavy smoking may increase the risk of ESCC particularly in individuals with the flushing response...
  46. ncbi request reprint Colorectal cancer screening using fecal occult blood test and subsequent risk of colorectal cancer: a prospective cohort study in Japan
    Kyung Jae Lee
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Detect Prev 31:3-11. 2007
    ..To investigate prospectively the association between colorectal cancer screening and subsequent risk of colorectal cancer death in a large-scale population-based cohort study (the JPHC study) with a 13-year follow-up period in Japan...
  47. doi request reprint Prognostic significance of mitotic figures in metastatic mammary ductal carcinoma to the lymph nodes
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, Chuo Ku, 104 0045, Tokyo, Japan
    Hum Pathol 42:1823-32. 2011
    ..In conclusion, this study clearly confirmed the excellent outcome predictive power of the number of mitotic figures in metastatic mammary carcinoma to the lymph nodes...
  48. doi request reprint Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of colorectal cancer: a hospital-based case-control study in Japan
    Minatsu Kobayashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Scand J Gastroenterol 44:952-9. 2009
    ..A further objective was to investigate the possible effect of genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 on colorectal cancer...
  49. ncbi request reprint Plasma levels of C-reactive protein and serum amyloid A and gastric cancer in a nested case-control study: Japan Public Health Center-based prospective study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Carcinogenesis 31:712-8. 2010
    ..005). In conclusion, our results suggest that those who react strongly to inflammation or who have a high host immune response, as reflected by extremely elevated plasma levels of CRP and SAA, are at a high risk to develop gastric cancer...
  50. ncbi request reprint Daily total physical activity level and premature death in men and women: results from a large-scale population-based cohort study in Japan (JPHC study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 18:522-30. 2008
    ..We prospectively examined the association between daily total physical activity level (METs/day) and subsequent risk of all-cause mortality and mortalities from cancer, heart disease, and cerebrovascular disease...
  51. ncbi request reprint Dietary calcium, vitamin D, and the risk of colorectal cancer
    Junko Ishihara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Clin Nutr 88:1576-83. 2008
    ..Calcium and vitamin D have a potential protective effect against colorectal cancer...
  52. doi request reprint Leisure-time physical activity and breast cancer risk by hormone receptor status: effective life periods and exercise intensity
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tsukiji 5 1 1, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Causes Control 21:1787-98. 2010
    ..We investigated associations between age- and intensity-specific leisure-time physical activity and ER/PR-defined breast cancer risk...
  53. doi request reprint Plasma levels of carotenoids, retinol and tocopherol and the risk of gastric cancer in Japan: a nested case-control study
    Christina Persson
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo ku 104 0045, Tokyo, Japan
    Carcinogenesis 29:1042-8. 2008
    ..Our findings suggest that those who have very low plasma levels of alpha-carotene and beta-carotene are at a higher risk of gastric cancer...
  54. doi request reprint Coffee consumption and risk of endometrial cancer: a prospective study in Japan
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 123:2406-10. 2008
    ..Coffee consumption may be associated with a decreased risk of endometrial cancer...
  55. ncbi request reprint Grading system for lymph vessel tumor emboli: significant outcome predictor for patients with invasive ductal carcinoma of the breast who received neoadjuvant therapy
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
    Mod Pathol 23:581-92. 2010
    ....
  56. doi request reprint Atypical tumor-stromal fibroblasts in invasive ductal carcinomas of the breast treated with neoadjuvant therapy
    Takahiro Hasebe
    Clinical Trials and Practice Support Division, Pathology Consultation Service, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, 104 0045, Japan
    Hum Pathol 42:998-1006. 2011
    ....
  57. doi request reprint Validity of self-reported cancer among a Japanese population: recent results from a population-based prospective study in Japan (JPHC Study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol 35:250-3. 2011
    ..Self-reported diagnoses of cancer do not provide sufficient accuracy for the detection and classification of incident cancers. Our findings may be extrapolated to other Japanese populations...
  58. doi request reprint High dietary intake of magnesium may decrease risk of colorectal cancer in Japanese men
    Enbo Ma
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Nutr 140:779-85. 2010
    ..There were no significant associations between magnesium intake and cancer risk in women. Higher dietary intake of magnesium may decrease the risk of CRC in Japanese men...
  59. ncbi request reprint Plasma testosterone and sex hormone-binding globulin concentrations and the risk of prostate cancer among Japanese men: a nested case-control study
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Sci 101:2652-7. 2010
    ..In conclusion, in this nested case-control study, concentrations of circulating total testosterone, free testosterone or SHBG were not strongly associated with a risk for total prostate cancer...
  60. doi request reprint Plasma isoflavones and the risk of lung cancer in women: a nested case-control study in Japan
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, 104 0045 Japan
    Cancer Epidemiol Biomarkers Prev 20:419-27. 2011
    ....
  61. doi request reprint Impact of viral load of hepatitis C on the incidence of hepatocellular carcinoma: A population-based cohort study (JPHC Study)
    Seiji Ishiguro
    National Cancer Center, Tokyo, Japan
    Cancer Lett 300:173-9. 2011
    ..The risk was 3.86-fold higher (CI; 1.73-8.62) for genotype 1 than genotype 2. Our findings suggest that HCV viremia strongly influences the occurrence of hepatocellular carcinoma without titer-dependence...
  62. ncbi request reprint Metaplastic carcinoma of the breast
    Nao Okada
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo 104 0045, Japan
    Hum Pathol 41:960-70. 2010
    ....
  63. doi request reprint Grading system for lymph vessel tumor emboli: significant outcome predictor for invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo 104 0045, Japan
    Hum Pathol 41:706-15. 2010
    ..The grading system for lymph vessel tumor emboli is an excellent histologic grading system for predicting the outcome of patients with invasive ductal carcinoma of the breast...
  64. ncbi request reprint Alcohol consumption-associated breast cancer incidence and potential effect modifiers: the Japan Public Health Center-based Prospective Study
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Int J Cancer 127:685-95. 2010
    ..15). Excessive alcohol intake was associated with an increase in the risk of breast cancer in this population. There was no statistical evidence for effect modification...
  65. ncbi request reprint Effect of soy isoflavones on endometriosis: interaction with estrogen receptor 2 gene polymorphism
    Masaki Tsuchiya
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Epidemiology 18:402-8. 2007
    ..We examined associations among soy isoflavone intake, estrogen receptor 2 (ESR2) gene polymorphisms and risk of endometriosis...
  66. doi request reprint Metabolic factors and subsequent risk of hepatocellular carcinoma by hepatitis virus infection status: a large-scale population-based cohort study of Japanese men and women (JPHC Study Cohort II)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Causes Control 20:741-50. 2009
    ..We prospectively examined whether metabolic factors predicts the subsequent risk of HCC in the Japan Public Health Center-based Prospective Study Cohort II, in consideration of hepatitis virus infection status...
  67. ncbi request reprint Reproductive factors, exogenous female hormone use and colorectal cancer risk: the Japan Public Health Center-based Prospective Study
    Munira Akhter
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 17:515-24. 2008
    ..59). In contrast, no statistically significant association was found for rectal cancer. These findings suggest that late age at first birth is associated with a reduced risk of colon cancer in postmenopausal Japanese women...
  68. ncbi request reprint Physical activity and risk of colorectal cancer in Japanese men and women: the Japan Public Health Center-based prospective study
    Kyung Jae Lee
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo, Japan
    Cancer Causes Control 18:199-209. 2007
    ....
  69. ncbi request reprint Plasma folate and risk of colorectal cancer in a nested case-control study: the Japan Public Health Center-based prospective study
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer Causes Control 19:67-74. 2008
    ..We investigated the association between plasma folate and the risk of colorectal cancer in a nested case-control study...
  70. ncbi request reprint Effect of Helicobacter pylori infection combined with CagA and pepsinogen status on gastric cancer development among Japanese men and women: a nested case-control study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 15:1341-7. 2006
    ..Although accumulating evidence suggests that Helicobacter pylori plays a role in gastric carcinogenesis, the magnitude of the risk remains uncertain...
  71. ncbi request reprint Dietary soy and isoflavone intake and risk of colorectal cancer in the Japan public health center-based prospective study
    Munira Akhter
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Epidemiol Biomarkers Prev 17:2128-35. 2008
    ..These findings suggest that the intake of isoflavones, miso soup, and soy food has no substantial effect on the risk of colorectal cancer in Japanese men and women...
  72. doi request reprint Serum organochlorines and breast cancer risk in Japanese women: a case-control study
    Hiroaki Itoh
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Causes Control 20:567-80. 2009
    ..Here, we examined these associations in Japanese women in the largest study in Asian women to date...
  73. ncbi request reprint Low intake of vitamin B-6 is associated with increased risk of colorectal cancer in Japanese men
    Junko Ishihara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    J Nutr 137:1808-14. 2007
    ..Our results support previous evidence that low vitamin B-6 intake is associated with an increased risk of colorectal cancer. In particular, a higher intake of vitamin B-6 appears beneficial in men with higher alcohol intake...
  74. ncbi request reprint Visceral fat volume and the prevalence of colorectal adenoma
    Taiki Yamaji
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Epidemiol 170:1502-11. 2009
    ..The mechanisms of this potential association between visceral adiposity and colorectal carcinogenesis warrant further investigation...
  75. ncbi request reprint Association between lung cancer incidence and family history of lung cancer: data from a large-scale population-based cohort study, the JPHC study
    Jun ichi Nitadori
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045 Japan
    Chest 130:968-75. 2006
    ..To clarify the possibility of a hereditary predisposition to lung cancer, we investigated the association between a family history of lung cancer and subsequent risk of lung cancer in a large-scale, population-based cohort study...
  76. ncbi request reprint Body mass index, physical activity and the risk of pancreatic cancer in relation to smoking status and history of diabetes: a large-scale population-based cohort study in Japan--the JPHC study
    Juhua Luo
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Cancer Causes Control 18:603-12. 2007
    ..In particular, we explored how these effects were influenced by smoking status and a history of diabetes...
  77. ncbi request reprint Soy product and isoflavone consumption in relation to prostate cancer in Japanese men
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo 104 0045 Japan
    Cancer Epidemiol Biomarkers Prev 16:538-45. 2007
    ..52 [95% confidence interval (95% CI), 0.30-0.90], 0.50 (95% CI, 0.28-0.88), and 0.52 (95% CI, 0.29-0.90), respectively. In conclusion, we found that isoflavone intake was associated with a decreased risk of localized prostate cancer...
  78. ncbi request reprint hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gastric cancer risk in Japanese populations
    Hiromasa Tsukino
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Cancer Sci 95:977-83. 2004
    ..The results of the present study suggest that patients with atrophic gastritis in conjunction with the hOGG1 Cys allele might have a higher susceptibility to gastric cancer...
  79. ncbi request reprint Serum triglycerides and colorectal adenoma in a case-control study among cancer screening examinees (Japan)
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Causes Control 17:1245-52. 2006
    ..However, whether the association can be modified by smoking is unknown. We cross-sectionally investigated the association of serum triglycerides with the risk of adenoma by smoking status...
  80. ncbi request reprint Association between polymorphisms in glutathione S-transferase Mu3 and IgG titer levels in serum against Helicobacter pylori
    Masayuki Tatemichi
    Department of Hygiene and Preventive Medicine, School of Medicine, Showa University, Shinagawa ku, Tokyo, Japan
    J Hum Genet 54:557-63. 2009
    ..pylori. GST-M3 activity is possibly involved in protection against mucosal atrophy caused by H. pylori as the levels of IgG titer and PGI are linked to mucosal status...
  81. doi request reprint p53 expression in tumor-stromal fibroblasts forming and not forming fibrotic foci in invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Service, National Cancer Center, Chuo Ku, Tokyo, Japan
    Mod Pathol 23:662-72. 2010
    ....
  82. ncbi request reprint Prospective study showing that dietary vitamin C reduced the risk of age-related cataracts in a middle-aged Japanese population
    Masao Yoshida
    Dept of Public Health, Kyorin University School of Medicine, Tokyo, Japan
    Eur J Nutr 46:118-24. 2007
    ....
  83. ncbi request reprint Coffee consumption and risk of colorectal cancer in a population-based prospective cohort of Japanese men and women
    Kyung Jae Lee
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 121:1312-8. 2007
    ..These findings suggest that coffee consumption may lower the risk of colon cancer among Japanese women...
  84. ncbi request reprint Bowel movement, state of stool, and subsequent risk for colorectal cancer: the Japan public health center-based prospective study
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 16:888-94. 2006
    ..Evidence about whether irregular bowel movements or unusual stool conditions are associated with colorectal cancer is still inconsistent...
  85. ncbi request reprint Generalizability of relative risk estimates from a well-defined population to a general population
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Eur J Epidemiol 21:253-62. 2006
    ..06). Our results suggest that even for RRs, the extrapolation of estimates for a sample from a well-defined population to a general population may not be possible...
  86. ncbi request reprint Body size and risk for breast cancer in relation to estrogen and progesterone receptor status in Japan
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 17:304-12. 2007
    ..The aim of this study is to examine the association of height, weight, and body mass index (BMI) with breast cancer and its hormone receptor-defined subtype in a low-risk population...
  87. ncbi request reprint Body mass index, body height, and subsequent risk of colorectal cancer in middle-aged and elderly Japanese men and women: Japan public health center-based prospective study
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Causes Control 16:839-50. 2005
    ..To investigate the association of body mass index (BMI) or body height with colorectal cancer incidence in a population-based prospective study...
  88. doi request reprint Impact of metabolic factors on subsequent cancer risk: results from a large-scale population-based cohort study in Japan
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, International Medical Center of Japan, Tokyo, Japan
    Eur J Cancer Prev 18:240-7. 2009
    ..21-2.55). Metabolic factors in the aggregate may have little impact on total cancer risk in the Japanese population, although the association between specific components and specific cancers suggests an etiologic link between them...
  89. ncbi request reprint Plasma C-reactive protein and risk of colorectal cancer in a nested case-control study: Japan Public Health Center-based prospective study
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 15:690-5. 2006
    ..In conclusion, plasma levels of C-reactive protein were associated with a subsequent risk of colon cancer. Inflammation may be involved at the early stage of colon tumor growth...
  90. pmc Plasma organochlorines and subsequent risk of prostate cancer in Japanese men: a nested case-control study
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Environ Health Perspect 118:659-65. 2010
    ..To our knowledge, this is the first prospective study to investigate the association between blood levels of organochlorines and prostate cancer risk...
  91. doi request reprint Interaction between adiponectin and leptin influences the risk of colorectal adenoma
    Taiki Yamaji
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Res 70:5430-7. 2010
    ..Our findings provide the first epidemiologic evidence for interactive effects of adiponectin and leptin in the early stage of colorectal tumorigenesis, distinct from their involvement in insulin resistance...
  92. doi request reprint A new histological classification for intra-operative histological examination of the ductal resection margin in cholangiocarcinoma
    Masaru Konishi
    Upper Gastric Surgery Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba, Japan
    Cancer Sci 100:255-60. 2009
    ....
  93. ncbi request reprint Breast cancer in first-degree relatives and risk of lung cancer: assessment of the existence of gene sex interactions
    Masaki Tsuchiya
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Jpn J Clin Oncol 37:419-23. 2007
    ....
  94. doi request reprint Plasma isoflavones and subsequent risk of prostate cancer in a nested case-control study: the Japan Public Health Center
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji Chuo ku Tokyo 104 0045 Japan
    J Clin Oncol 26:5923-9. 2008
    ..Given the preventive effects of isoflavones on carcinogenesis in the prostate in many nonhuman studies and the high consumption of isoflavones in Japanese, this low incidence may be partly due to the effects of soy...
  95. ncbi request reprint Cancer mortality among Japanese immigrants and their descendants in the state of São Paulo, Brazil, 1999-2001
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo 104 0045, Japan
    Jpn J Clin Oncol 34:673-80. 2004
    ..Only a few studies on the mortality of Japanese immigrants have been conducted in Brazil despite a large population of Japanese immigrants and their different environment and lifestyle from Japanese living in Japan...
  96. ncbi request reprint Passive smoking and lung cancer in Japanese non-smoking women: a prospective study
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji Chuo ku, Tokyo, Japan
    Int J Cancer 122:653-7. 2008
    ..93, 95% CI 0.88-4.23). These findings confirm that passive smoking is a risk factor for lung cancer, especially for adenocarcinoma among Japanese women...
  97. ncbi request reprint Green tea consumption and prostate cancer risk in Japanese men: a prospective study
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Epidemiol 167:71-7. 2008
    ..52 (95% confidence interval: 0.28, 0.96) for men drinking 5 or more cups/day compared with less than 1 cup/day (p(trend) = 0.01). Green tea may be associated with a decreased risk of advanced prostate cancer...
  98. doi request reprint Tumor histology in lymph vessels and lymph nodes for the accurate prediction of outcome among breast cancer patients treated with neoadjuvant chemotherapy
    Nobuko Tamura
    Department of Breast Surgery, National Cancer Center Hospital, Chuo Ku, Tokyo
    Cancer Sci 100:1823-33. 2009
    ....
  99. ncbi request reprint Secular trends in cancer mortality among Japanese immigrants in the state of São Paulo, Brazil, 1979-2001
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 17:1-8. 2008
    ..Secular trends in mortality confirm the relative importance of environment in the development of cancer...
  100. doi request reprint Plasma tea polyphenols and gastric cancer risk: a case-control study nested in a large population-based prospective study in Japan
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Epidemiol Biomarkers Prev 17:343-51. 2008
    ..02). Cigarette smoking was suggested to play a role as an effect modifier, which explains in part the different patterns observed by gender...