H Iwahashi

Summary

Affiliation: National Institute of Bioscience and Human-Technology
Country: Japan

Publications

  1. ncbi request reprint Barotolerance is dependent on both trehalose and heat shock protein 104 but is essentially different from thermotolerance in Saccharomyces cerevisiae
    H Iwahashi
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, Ibaraki, Japan
    Lett Appl Microbiol 25:43-7. 1997
  2. ncbi request reprint Effect of temperature on the role of Hsp104 and trehalose in barotolerance of Saccharomyces cerevisiae
    H Iwahashi
    National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki, Japan
    FEBS Lett 416:1-5. 1997
  3. pmc Evidence for the interplay between trehalose metabolism and Hsp104 in yeast
    H Iwahashi
    National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki 305 8566, Japan
    Appl Environ Microbiol 64:4614-7. 1998
  4. pmc Evidence for contribution of neutral trehalase in barotolerance of Saccharomyces cerevisiae
    H Iwahashi
    National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki 305, Japan
    Appl Environ Microbiol 66:5182-5. 2000
  5. pmc Direct evidence for the intracellular localization of Hsp104 in Saccharomyces cerevisiae by immunoelectron microscopy
    R Kawai
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, Tsukuba, Ibaraki, 305 8566, Japan
    Cell Stress Chaperones 4:46-53. 1999
  6. ncbi request reprint Contribution of Hsc70 to barotolerance in the yeast Saccharomyces cerevisiae
    H Iwahashi
    National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki, Japan
    Extremophiles 5:417-21. 2001
  7. ncbi request reprint Bioassay of cadmium using a DNA microarray: genome-wide expression patterns of Saccharomyces cerevisiae response to cadmium
    Y Momose
    Human Stress Signal Research Center and Research Institute of Biological Resources, The National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Environ Toxicol Chem 20:2353-60. 2001
  8. ncbi request reprint The biological effects of high-pressure gas on the yeast transcriptome
    H Matsuoka
    National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Braz J Med Biol Res 38:1267-72. 2005
  9. ncbi request reprint Stabilization of two families of critical targets for hyperthermic cell killing and acquired thermotolerance of yeast cells
    K Obuchi
    National Institute of Bioscience and Human Technology, AIST, Ibaraki, Japan
    Yeast 14:1249-55. 1998
  10. ncbi request reprint Hsp104 responds to heat and oxidative stress with different intracellular localization in Saccharomyces cerevisiae
    K Fujita
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, Ibaraki, Japan
    Biochem Biophys Res Commun 248:542-7. 1998

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Barotolerance is dependent on both trehalose and heat shock protein 104 but is essentially different from thermotolerance in Saccharomyces cerevisiae
    H Iwahashi
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, Ibaraki, Japan
    Lett Appl Microbiol 25:43-7. 1997
    ..Thus, trehalose and hsp104 are important factors for barotolerance and thermotolerance, but trehalose is more important for barotolerance than for thermotolerance...
  2. ncbi request reprint Effect of temperature on the role of Hsp104 and trehalose in barotolerance of Saccharomyces cerevisiae
    H Iwahashi
    National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki, Japan
    FEBS Lett 416:1-5. 1997
    ..These results suggest that the role of Hsp104 in barotolerance is temperature dependent in contrast to trehalose...
  3. pmc Evidence for the interplay between trehalose metabolism and Hsp104 in yeast
    H Iwahashi
    National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki 305 8566, Japan
    Appl Environ Microbiol 64:4614-7. 1998
    ..These results suggest that during heat shock, Hsp104 contributes to the simultaneous increase in both accumulation and degradation of trehalose...
  4. pmc Evidence for contribution of neutral trehalase in barotolerance of Saccharomyces cerevisiae
    H Iwahashi
    National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki 305, Japan
    Appl Environ Microbiol 66:5182-5. 2000
    ..Our results suggest that neutral trehalase contributes to barotolerance, especially during recovery...
  5. pmc Direct evidence for the intracellular localization of Hsp104 in Saccharomyces cerevisiae by immunoelectron microscopy
    R Kawai
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, Tsukuba, Ibaraki, 305 8566, Japan
    Cell Stress Chaperones 4:46-53. 1999
    ....
  6. ncbi request reprint Contribution of Hsc70 to barotolerance in the yeast Saccharomyces cerevisiae
    H Iwahashi
    National Institute of Bioscience and Human Technology, Tsukuba, Ibaraki, Japan
    Extremophiles 5:417-21. 2001
    ..These results suggest that Hsc70 contributes to barotolerance during exponentially growing conditions as does Hsp104 during heat-shock treatment...
  7. ncbi request reprint Bioassay of cadmium using a DNA microarray: genome-wide expression patterns of Saccharomyces cerevisiae response to cadmium
    Y Momose
    Human Stress Signal Research Center and Research Institute of Biological Resources, The National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Environ Toxicol Chem 20:2353-60. 2001
    ..Based on these results, we concluded that DNA microarrays are very useful instruments for creating new bioassay systems and finding genetic promoters of stress indicators...
  8. ncbi request reprint The biological effects of high-pressure gas on the yeast transcriptome
    H Matsuoka
    National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Braz J Med Biol Res 38:1267-72. 2005
    ..These results suggest the possibility of applying yeast DNA microarray to gas bioassays up to 40 MPa. We therefore think that "bioassays" are ideal for use in environmental control and protection studies...
  9. ncbi request reprint Stabilization of two families of critical targets for hyperthermic cell killing and acquired thermotolerance of yeast cells
    K Obuchi
    National Institute of Bioscience and Human Technology, AIST, Ibaraki, Japan
    Yeast 14:1249-55. 1998
    ..On the other hand, both heat-shock response and arrest in stationary phase stabilizes the other family of targets that, in addition to the previous one, is responsible for phase 2 death...
  10. ncbi request reprint Hsp104 responds to heat and oxidative stress with different intracellular localization in Saccharomyces cerevisiae
    K Fujita
    National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, Ibaraki, Japan
    Biochem Biophys Res Commun 248:542-7. 1998
    ..These findings suggest Hsp104 adaptively responds to comprehensive stress and participates in an emergent rescue function as a molecular chaperone...
  11. ncbi request reprint Calorimetric characterization of critical targets for killing and acquired thermotolerance in yeast
    K Obuchi
    National Institute of Bioscience and Human Technology, AIST, 1 1 Higashi, Tsukuba, Ibaraki 305 8566, Japan
    Yeast 16:111-9. 2000
    ..This agreement suggests that the microsomal fraction may contain critical targets, and that trehalose accumulation in the heat-shocked and in the stationary phase yeast cells is a stabilizer of cellular components...
  12. ncbi request reprint Yeast pheromone signaling pathway as a bioassay to assess the effect of chemicals on mammalian peptide hormones
    K Fujita
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology AIST, 1 1 Higashi 1, Tsukuba, 305 8566, Ibaraki, Japan
    Ecotoxicol Environ Saf 56:358-66. 2003
    ..Analysis of the yeast pheromone signaling pathway helps to establish chemical toxicity assay models for mammalian peptide signal transduction pathways...
  13. ncbi request reprint A yeast DNA microarray for the evaluation of toxicity in environmental water containing burned ash
    Hyun J Kim
    National Institute of Advanced Industrial Science and Technology, Central 6, Higashi 1 1 1, Tsukuba, Ibaraki, Japan
    Environ Monit Assess 92:253-72. 2004
    ..Also, the possibility of mutagenicity of the burned ash was suggested on the basis of the DNA repair related genes...
  14. ncbi request reprint Comprehensive gene expression analysis of the response to straight-chain alcohols in Saccharomyces cerevisiae using cDNA microarray
    K Fujita
    Japan Bioindustry Association JBA, Daicel Chemical Industries, Ltd, Branch, Tsukuba, Japan
    J Appl Microbiol 97:57-67. 2004
    ..The purpose of this study was to examine the gene expression profiles of yeast Saccharomyces cerevisiae subjected to straight-chain alcohols...
  15. ncbi request reprint Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy
    H Iwahashi
    Department of Medical Genetics, Biomedical Research Center, Osaka University Medical School, Suita, Japan
    Nature 390:413-7. 1997
    ..Our results indicate that an absent or decreased anti-apoptotic activity of SMN in concert with Bcl-2 underlies the pathogenesis of SMA...