K Inui

Summary

Affiliation: National Institute for Physiological Sciences
Country: Japan

Publications

  1. ncbi request reprint Microneurographic study of C fiber discharges induced by CO2 laser stimulation in humans
    Yunhai Qiu
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki 444 8585, Japan
    Neurosci Lett 353:25-8. 2003
  2. ncbi request reprint Cortical processing of noxious information in humans: a magnetoencephalographic study
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, Japan
    Suppl Clin Neurophysiol 59:127-33. 2006
  3. ncbi request reprint Higher anticipated force required a stronger inhibitory process in go/nogo tasks
    Hiroki Nakata
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Clin Neurophysiol 117:1669-76. 2006
  4. doi request reprint Discrepancy between reaction time and visual evoked magnetic response latency under priming
    Akiko Hashimoto
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Neurosci Res 60:244-9. 2008
  5. ncbi request reprint Pain-related evoked potentials are modulated across the cardiac cycle
    Louisa Edwards
    International Centre for Health and Exercise Research, University of Birmingham, Birmingham B152TT, UK
    Pain 137:488-94. 2008
  6. pmc Prepulse inhibition of auditory change-related cortical responses
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, 444 8585, Japan
    BMC Neurosci 13:135. 2012
  7. pmc Auditory sustained field responses to periodic noise
    Sumru Keceli
    Department of Integrative Physiology, National Institute for Physiological Sciences, Nishigohnaka 38, Myodaiji, Okazaki City, 444 8585, Japan
    BMC Neurosci 13:7. 2012
  8. doi request reprint Pain perception in humans: use of intraepidermal electrical stimulation
    Koji Inui
    Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Aichi, Japan
    J Neurol Neurosurg Psychiatry 83:551-6. 2012
  9. pmc A transition from unimodal to multimodal activations in four sensory modalities in humans: an electrophysiological study
    Emi Tanaka
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki 444 8585, Japan
    BMC Neurosci 9:116. 2008
  10. pmc Common cortical responses evoked by appearance, disappearance and change of the human face
    Emi Tanaka
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, Japan
    BMC Neurosci 10:38. 2009

Detail Information

Publications80

  1. ncbi request reprint Microneurographic study of C fiber discharges induced by CO2 laser stimulation in humans
    Yunhai Qiu
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki 444 8585, Japan
    Neurosci Lett 353:25-8. 2003
    ..1+/-0.3 m/s. The mean latency of the positive peak of cerebral potentials was 1327.4+/-46.2 ms. These findings indicated that this new stimulation method selectively activated C-fiber nociceptors of the skin...
  2. ncbi request reprint Cortical processing of noxious information in humans: a magnetoencephalographic study
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, Japan
    Suppl Clin Neurophysiol 59:127-33. 2006
  3. ncbi request reprint Higher anticipated force required a stronger inhibitory process in go/nogo tasks
    Hiroki Nakata
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Clin Neurophysiol 117:1669-76. 2006
    ..We investigated the effect of the inhibitory process with increasing muscle force on event-related potentials (ERPs) and motor evoked potentials (MEPs)...
  4. doi request reprint Discrepancy between reaction time and visual evoked magnetic response latency under priming
    Akiko Hashimoto
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Neurosci Res 60:244-9. 2008
    ..However, in contrast, the reaction time to S2 in all SOA conditions was significantly shortened as compared with that in the control condition, suggesting dissociation between processing in the visual cortex and motor processing...
  5. ncbi request reprint Pain-related evoked potentials are modulated across the cardiac cycle
    Louisa Edwards
    International Centre for Health and Exercise Research, University of Birmingham, Birmingham B152TT, UK
    Pain 137:488-94. 2008
    ..Pain ratings did not vary across the cardiac cycle. These data support the hypothesis that arterial baroreceptors modulate the processing of nociception during each cardiac cycle...
  6. pmc Prepulse inhibition of auditory change-related cortical responses
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, 444 8585, Japan
    BMC Neurosci 13:135. 2012
    ..PPI is usually observed by use of a startle reflex such as blinking following an intense sound. A similar phenomenon has not been reported for cortical responses...
  7. pmc Auditory sustained field responses to periodic noise
    Sumru Keceli
    Department of Integrative Physiology, National Institute for Physiological Sciences, Nishigohnaka 38, Myodaiji, Okazaki City, 444 8585, Japan
    BMC Neurosci 13:7. 2012
    ..In order to investigate the effect of repetition rate on cortical responses, we analyzed the auditory sustained fields evoked by periodic and aperiodic noises using magnetoencephalography...
  8. doi request reprint Pain perception in humans: use of intraepidermal electrical stimulation
    Koji Inui
    Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Aichi, Japan
    J Neurol Neurosurg Psychiatry 83:551-6. 2012
    ..As IES does not require expensive equipment, and is easy to control, it would seem useful for pain research as well as clinical tests...
  9. pmc A transition from unimodal to multimodal activations in four sensory modalities in humans: an electrophysiological study
    Emi Tanaka
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki 444 8585, Japan
    BMC Neurosci 9:116. 2008
    ....
  10. pmc Common cortical responses evoked by appearance, disappearance and change of the human face
    Emi Tanaka
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, Japan
    BMC Neurosci 10:38. 2009
    ....
  11. ncbi request reprint Timing of early activity in the visual cortex as revealed by simultaneous MEG and ERG recordings
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Neuroimage 30:239-44. 2006
    ....
  12. ncbi request reprint Pain processing within the primary somatosensory cortex in humans
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Eur J Neurosci 18:2859-66. 2003
    ....
  13. ncbi request reprint Serial processing in the human somatosensory system
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Cereb Cortex 14:851-7. 2004
    ..5, 18.0, 22.4 and 21.7 ms, respectively. The differences of onset latencies among these activations indicated the serial mode of processing both through the postcentral gyrus and through the primary and secondary somatosensory cortices...
  14. ncbi request reprint Serial and parallel processing in the human auditory cortex: a magnetoencephalographic study
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki 444 8585, Japan
    Cereb Cortex 16:18-30. 2006
    ....
  15. ncbi request reprint Temporal analysis of cortical mechanisms for pain relief by tactile stimuli in humans
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Cereb Cortex 16:355-65. 2006
    ....
  16. ncbi request reprint Temporal analysis of the flow from V1 to the extrastriate cortex in humans
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    J Neurophysiol 96:775-84. 2006
    ..These results suggest similar mechanisms of the serial cortico-cortical processing of sensory information among all sensory areas of the cortex...
  17. pmc Non-linear laws of echoic memory and auditory change detection in humans
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    BMC Neurosci 11:80. 2010
    ..Here we used an auditory change-related N1 subcomponent (change-N1) of event-related brain potentials to investigate cortical mechanisms underlying change detection and echoic memory...
  18. ncbi request reprint A comparative magnetoencephalographic study of cortical activations evoked by noxious and innocuous somatosensory stimulations
    K Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Neuroscience 120:235-48. 2003
    ..Our data also implied that activities in the amygdala/hippocampal formation represented common effects of noxious and tactile stimulations...
  19. ncbi request reprint Preferential stimulation of Adelta fibers by intra-epidermal needle electrode in humans
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Pain 96:247-52. 2002
    ....
  20. ncbi request reprint Pain-related magnetic fields evoked by intra-epidermal electrical stimulation in humans
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, 444 8585, Okazaki, Japan
    Clin Neurophysiol 113:298-304. 2002
    ..We recently developed a new method for the preferential stimulation of Adelta fibers in humans. The aim of the present study was to examine whether this method can serve as an appropriate stimulus in a magnetoencephalographic study...
  21. pmc Echoic memory of a single pure tone indexed by change-related brain activity
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki 444 8585, Japan
    BMC Neurosci 11:135. 2010
    ..To test this hypothesis, we examined whether the single presentation of a sound is enough to elicit a change-related cortical response, and therefore, shape a memory trace enough to separate a subsequent stimulus...
  22. ncbi request reprint Temporal slow waves and cerebrovascular diseases
    K Inui
    Department of Psychiatry, Mie University School of Medicine, Mie, Japan
    Psychiatry Clin Neurosci 55:525-31. 2001
    ..Since TLID, TMSSA and BORTT have many clinical and electrographical similarities, we consider that these findings should be grouped into one EEG entity which appears in association with mild cerebrovascular dysfunction...
  23. ncbi request reprint Conduction velocity of the spinothalamic tract in humans as assessed by CO(2) laser stimulation of C-fibers
    Y Qiu
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji Okazaki, 444 8585, Japan
    Neurosci Lett 311:181-4. 2001
    ..2+/-0.6 m/s, which was significantly lower than the CV of the Adelta-fibers (10.0+/-4.5 m/s). This technique is novel and simple, and should be useful as a diagnostic tool for assessing the level of spinal cord lesions...
  24. ncbi request reprint Electrical-induced pain diminishes somatosensory evoked magnetic cortical fields
    T D Tran
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Clin Neurophysiol 114:1704-14. 2003
    ..To investigate the effect of conditioning painful stimulation on the early somatosensory magnetic fields (SEF) of test stimulation, in order to clarify the location of the gating effect of pain on tactile response...
  25. ncbi request reprint Early cortical activities evoked by noxious stimulation in humans
    Xiaohong Wang
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, 444 8585, Japan
    Exp Brain Res 180:481-9. 2007
    ..The results suggested that early cortical processing of noxious information occurs earlier than previous neurophysiological studies have estimated and that the temporal sequence of activations should be reconsidered...
  26. ncbi request reprint Cerebral activation by the signals ascending through unmyelinated C-fibers in humans: a magnetoencephalographic study
    T D Tran
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Neuroscience 113:375-86. 2002
    ..From our findings we suggest that parallel activation of SI and SII contralateral to the stimulation represents the first step in the cortical processing of C-fiber-related activities, probably related to second pain...
  27. ncbi request reprint Backward-masking: the effect of the duration of the second stimulus on recognition of the first stimulus
    A Hashimoto
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Neuroscience 137:1427-37. 2006
    ..We recorded event-related magnetic fields following a target stimulus followed by a masking stimulus to investigate the visual backward masking effect using a helmet-type magnetoencephalography system in humans...
  28. ncbi request reprint Cortical responses to noxious stimuli during sleep
    X Wang
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Neuroscience 128:177-86. 2004
    ..The main component 1 M as well as later magnetic fields were markedly attenuated during sleep, suggesting that all these cortical areas are involved in pain cognition...
  29. ncbi request reprint Facilitation of A[delta]-fiber-mediated acute pain by repetitive transcranial magnetic stimulation
    Y Tamura
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Neurology 62:2176-81. 2004
    ..The authors previously showed that rTMS over the primary motor cortex (M1) inhibited capsaicin-induced acute pain ascending through C-fibers...
  30. doi request reprint Effects of acute nicotine on somatosensory change-related cortical responses
    M Kodaira
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Neuroscience 229:20-6. 2013
    ....
  31. ncbi request reprint Brain processing of the signals ascending through unmyelinated C fibers in humans: an event-related functional magnetic resonance imaging study
    Yunhai Qiu
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Cereb Cortex 16:1289-95. 2006
    ....
  32. ncbi request reprint The characteristics of the nogo-N140 component in somatosensory go/nogo tasks
    Hiroki Nakata
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Neurosci Lett 397:318-22. 2006
    ..Therefore, nogo-N140 should be considered to reflect the inhibitory process especially in the hemisphere contralateral to the response hand and the sensory modality dependency of nogo potentials...
  33. doi request reprint Effects of prior sustained tactile stimulation on the somatosensory response to the sudden change of intensity in humans: an magnetoencephalography study
    N Otsuru
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Neuroscience 182:115-24. 2011
    ..The possibility that an activity of onset (with no conditioning stimulus) would be involved in the change-related activity was also discussed...
  34. doi request reprint Assessing Aδ fiber function with lidocaine using intraepidermal electrical stimulation
    Naofumi Otsuru
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    J Pain 11:621-7. 2010
    ..Therefore, it should be useful as a screening test for patients with neuropathy...
  35. ncbi request reprint Centrifugal regulation of human cortical responses to a task-relevant somatosensory signal triggering voluntary movement
    Tetsuo Kida
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Neuroimage 32:1355-64. 2006
    ..The present findings indicate a difference in function between the SI and SII in somatosensory-motor regulation...
  36. doi request reprint Automatic auditory off-response in humans: an MEG study
    Koya Yamashiro
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki 444 8585, Japan
    Eur J Neurosci 30:125-31. 2009
    ..The present results suggested that auditory on-N1m and off-N1m have similar physiological significance involved in responding to abrupt changes...
  37. doi request reprint Evoked magnetic fields following noxious laser stimulation of the thigh in humans
    Hiroki Nakata
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, 444 8585, Japan
    Neuroimage 42:858-68. 2008
    ..The mean peak latencies of SI, cSII, iSII and IPL were 152, 170, 181, and 183 ms, respectively. This is the first study to clarify the time course of the activities of SI, SII, and PPC in human pain processing using MEG...
  38. doi request reprint Cortical dynamics of visual change detection based on sensory memory
    Tomokazu Urakawa
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Neuroimage 52:302-8. 2010
    ..These results suggested that the MOG is an important cortical area relating to the sensory memory-based visual change-detecting system...
  39. doi request reprint Effects of stimulus field size and coherence of visual motion on cortical responses in humans: an MEG study
    Tomokazu Urakawa
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji Nishigo Naka 38, Okazaki 444 8585, Japan
    Neurosci Lett 488:294-8. 2011
    ....
  40. ncbi request reprint Time-varying cortical activations related to visual-tactile cross-modal links in spatial selective attention
    Tetsuo Kida
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Aichi, Japan
    J Neurophysiol 97:3585-96. 2007
    ..The results show that spatial attention enhances responses to tactile inputs in SII, independent of sensory modality attended. The underlying mechanism remains to be determined, but may be an increase in gain...
  41. doi request reprint A difference exists in somatosensory processing between the anterior and posterior parts of the tongue
    Kiwako Sakamoto
    ITAB Institute for Advanced Biomedical Technologies, University of Chieti, Chieti, Italy
    Neurosci Res 66:173-9. 2010
    ..The activity in BA 40 and ACC may imply that the posterior of the tongue belongs to the visceral system...
  42. doi request reprint The characteristics of no-go potentials with intraepidermal stimulation
    Hiroki Nakata
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Neuroreport 20:1149-54. 2009
    ..We suggest that cortical activities relating to response inhibitory processing are not dependent on the sensory modality used...
  43. doi request reprint Change-driven cortical activation in multisensory environments: an MEG study
    Emi Tanaka
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Neuroimage 48:464-74. 2009
    ..Thus, neural processes responsive to unimodal changes in the multisensory environment are distributed at different timing in these cortical areas...
  44. doi request reprint Somatosensory off-response in humans: an ERP study
    Koya Yamashiro
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, 444 8585, Japan
    Exp Brain Res 190:207-13. 2008
    ..In this network, the change is automatically detected using a memory trace by comparing the abrupt event (on or off) with the preceding condition (silent or repetitive stimuli)...
  45. doi request reprint Dynamics of within-, inter-, and cross-modal attentional modulation
    Tetsuo Kida
    National Institute for Physiological Sciences, Department of Integrative Physiology, 38 Nishigo naka, Myodaiji, Okazaki 444 8585, Japan
    J Neurophysiol 105:674-86. 2011
    ..Thus the results suggest different spatiotemporal dynamics of neural representations of cross-modal attention and intermodal or within-modal attention...
  46. doi request reprint The effect of smoking on pain-related evoked potentials
    Takahiro Miyazaki
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji cho, Okazaki 444 8585, Japan
    Brain Res 1313:185-91. 2010
    ..Smoking of a single tobacco cigarette did not show a subjectively perceivable extent of reduction in the intensity of evoked pain...
  47. doi request reprint Somatosensory off-response in humans: an MEG study
    Koya Yamashiro
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Neuroimage 44:1363-8. 2009
    ..We consider that activities in the parasylvian region are involved in the detection of changes at the body's surface...
  48. ncbi request reprint Multiple pathways for noxious information in the human spinal cord
    Takeshi Tsuji
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Pain 123:322-31. 2006
    ..Further studies are required to clarify the functional significance of these two pathways...
  49. ncbi request reprint Temporal dynamics of neural adaptation effect in the human visual ventral stream
    Yasuki Noguchi
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    J Neurosci 24:6283-90. 2004
    ....
  50. ncbi request reprint Human brain processing and central mechanisms of pain as observed by electro- and magneto-encephalography
    Ryusuke Kakigi
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, Japan
    J Chin Med Assoc 67:377-86. 2004
    ..This finding may suggest greater effects of cognitive or emotional functions on second pain than the first pain...
  51. ncbi request reprint Face representation in the human primary somatosensory cortex
    Binh T Nguyen
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki 444 8585, Japan
    Neurosci Res 50:227-32. 2004
    ..This is the first study showing that the facial skin areas in the human SI are located between the thumb and lower lip areas and close together...
  52. ncbi request reprint Movements modulate cortical activities evoked by noxious stimulation
    Hiroki Nakata
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Pain 107:91-8. 2004
    ..In addition, since VAS changes showed a similar relationship with the amplitude changes of cSII, cSII may play a role in pain perception...
  53. ncbi request reprint Cognitive processes in two-point discrimination: an ERP study
    Yohei Tamura
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Clin Neurophysiol 115:1875-84. 2004
    ..To elucidate the temporal features of the cognitive process in two-point discrimination (TPD)...
  54. ncbi request reprint Central mechanisms for two-point discrimination in humans
    Yohei Tamura
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, 444 8585, Okazaki, Japan
    Neurosci Lett 342:187-90. 2003
    ..The present results indicate that the TPD process involved evaluation of the distance between the stimuli relatively to that of the preceding stimuli, as well as evaluation of absolute distance between the stimuli...
  55. ncbi request reprint Effects of distraction on magnetoencephalographic responses ascending through C-fibers in humans
    Yunhai Qiu
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Clin Neurophysiol 115:636-46. 2004
    ..Using magnetoencephalography (MEG), we evaluated the cerebral regions relating to second pain perception ascending through C-fibers and investigated the effect of distraction on each region...
  56. ncbi request reprint Effects of a go/nogo task on event-related potentials following somatosensory stimulation
    Hiroki Nakata
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Clin Neurophysiol 115:361-8. 2004
    ..We investigated the effects of a go/nogo task on event-related potentials (ERPs) evoked by somatosensory stimuli...
  57. ncbi request reprint Mechanisms of differences in gating effects on short-and long-latency somatosensory evoked potentials relating to movement
    Hiroki Nakata
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, Japan
    Brain Topogr 15:211-22. 2003
    ..This study showed the difference in gating effects on somatosensory perception depending on time periods following stimulation, which may indicate an interaction between motor and somatosensory cortex...
  58. ncbi request reprint Effects of sleep on pain-related somatosensory evoked magnetic fields in humans
    Xiaohong Wang
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Brain Res Cogn Brain Res 17:388-99. 2003
    ..They are specifically enhanced by painful stimulation due to an increase of signals ascending through A-delta fibers, and are markedly decreased during sleep, because they much involve cognitive function...
  59. ncbi request reprint Effects of ISI and stimulus probability on event-related go/nogo potentials after somatosensory stimulation
    Hiroki Nakata
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, 444 8585, Okazaki, Japan
    Exp Brain Res 162:293-9. 2005
    ....
  60. ncbi request reprint Cerebral responses following stimulation of unmyelinated C-fibers in humans: electro- and magneto-encephalographic study
    Ryusuke Kakigi
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, 444 8585, Okazaki, Japan
    Neurosci Res 45:255-75. 2003
    ..Investigations of the cortical processing in pain perception including both first and second pain should provide a better understanding of pain perception and, therefore, contribute to pain relief in clinical medicine...
  61. ncbi request reprint Somato-motor inhibitory processing in humans: a study with MEG and ERP
    Hiroki Nakata
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, 444 8585, Japan
    Eur J Neurosci 22:1784-92. 2005
    ..Our findings combining MEG and ERPs clarified the spatial and temporal processing related to somato-motor inhibition caused in the posterior part of the inferior frontal sulci in the prefrontal cortex in humans...
  62. ncbi request reprint Differential modulation in human primary and secondary somatosensory cortices during the preparatory period of self-initiated finger movement
    Toshiaki Wasaka
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Eur J Neurosci 22:1239-47. 2005
    ..The opposite effects of movement on SI and SII cortices indicated that these cortical areas play a different role in the function of the sensorimotor integration and are affected differently by the centrifugal process...
  63. ncbi request reprint Intracerebral pain processing in a Yoga Master who claims not to feel pain during meditation
    Ryusuke Kakigi
    Department of Integrative Physiology, National Institute for Physiological Sciences, Nishigo naka 38, Myodaiji, Okazaki 444 8585, Japan
    Eur J Pain 9:581-9. 2005
    ..Though we cannot clearly explain this unusual condition in the Yoga Master, a change of multiple regions relating to pain perception could be responsible, since pain is a complex sensory and emotional experience...
  64. ncbi request reprint Conduction velocity of the spinothalamic tract following CO2 laser stimulation of C-fibers in humans
    Tuan Diep Tran
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, 444 8585 Japan
    Pain 95:125-31. 2002
    ....
  65. ncbi request reprint Mismatch responses related to temporal discrimination of somatosensory stimulation
    Kosuke Akatsuka
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, Aichi 444 8585, Japan
    Clin Neurophysiol 116:1930-7. 2005
    ..To determine the existence of a pre-attentively evoked somatosensory mismatch negativity component and to investigate the use of that component in objective clinical diagnostics...
  66. ncbi request reprint Face representation in the human secondary somatosensory cortex
    Binh T Nguyen
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki 444 8585, Japan
    Clin Neurophysiol 116:1247-53. 2005
    ..To investigate the somatotopic organization of the facial skin area in the secondary somatosensory cortex (SII) in humans...
  67. ncbi request reprint Functional relationship between human rolandic oscillations and motor cortical excitability: an MEG study
    Yohei Tamura
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Eur J Neurosci 21:2555-62. 2005
    ..In the framework of previous studies, the decrease in movement-related rebound may be regarded as a compensatory reaction to the inhibited cortical activity...
  68. ncbi request reprint Effects of attention, distraction and sleep on CO(2) laser evoked potentials related to C-fibers in humans
    Yunhai Qiu
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki, 444 8585, Japan
    Clin Neurophysiol 113:1579-85. 2002
    ..The objective of this study is to evaluate the effects of attention, distraction and sleep on CO(2) laser-evoked potentials (LEP) relating to C-fibers (ultra-late LEP)...
  69. ncbi request reprint Effects of sleep on pain-related somatosensory evoked potentials in humans
    Xiaohong Wang
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Neurosci Res 45:53-7. 2003
    ..3) N130-P240 are the pain-specific components ascending through A-delta fibers, and closely related to cognitive function, because they were much affected by consciousness, different from the components ascending through A-beta fibers...
  70. ncbi request reprint Electrophysiological studies on human pain perception
    Ryusuke Kakigi
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki 444 8585, Japan
    Clin Neurophysiol 116:743-63. 2005
    ..We reviewed the recent progress in electrophysiological studies using electroencephalography (EEG), magnetoencephalography (MEG) and repetitive transcranial magnetic stimulation (rTMS) on human pain perception...
  71. ncbi request reprint Sensory perception during sleep in humans: a magnetoencephalograhic study
    Ryusuke Kakigi
    Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444 8585, Japan
    Sleep Med 4:493-507. 2003
    ..We have no evidence to support either, but we prefer the latter, since it is difficult to consider why neuronal activities would be increased during sleep...
  72. doi request reprint Cortical dynamics of the visual change detection process
    Tomokazu Urakawa
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
    Psychophysiology 47:905-12. 2010
    ..These results suggest that automatic visual change detection is associated with the MOG activity...
  73. ncbi request reprint Temporal dynamics of adaptation to natural sounds in the human auditory cortex
    Christian F Altmann
    Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki 444 8585, Japan
    Cereb Cortex 18:1350-60. 2008
    ..Thus, our results suggest selectivity of the evoked magnetic field at 200 ms after stimulus onset in nonprimary auditory cortex for the spectral fine structure of complex sounds rather than their temporal dynamics...
  74. ncbi request reprint [Central mechanisms of pain perception]
    Koji Inui
    Department of Integrative Physiology, National Institute for Physiological Sciences, 38 Nishigo naka, Myodaiji cho, Okazaki shi, Aichi 444 8585, Japan
    No To Shinkei 58:5-15. 2006
  75. doi request reprint Dipole source analysis of temporal slow waves in the elderly
    Eishi Motomura
    Department of Psychiatry, Division of Neuroscience, Institute of Medical Science, Mie University Graduate School of Medicine, Tsu, Japan
    Neuropsychobiology 57:9-13. 2008
    ..The physiological significance of TLID has not been clarified; however, our previous studies suggest that TLID are associated with mild cerebrovascular dysfunction...
  76. ncbi request reprint Late-onset depression: can EEG abnormalities help in clinical sub-typing?
    Eishi Motomura
    Department of Psychiatry, Mie University School of Medicine, Edobashi, Tsu, Mie 514 8507, Japan
    J Affect Disord 68:73-9. 2002
    ..The purpose of this study was to determine the frequency of EEG abnormalities indicative of mild cerebrovascular dysfunction in patients with late-onset depression and to correlate these abnormalities with clinical features...
  77. ncbi request reprint [Physiological study on nociception]
    Ryusuke Kakigi
    Masui 51:S115-24. 2002
  78. ncbi request reprint Inner experience of pain: imagination of pain while viewing images showing painful events forms subjective pain representation in human brain
    Yuichi Ogino
    Department of Anesthesiology, Gunma University Graduate School of Medicine, 3 39 22 Showamachi, Maebashi 371 8511, Japan
    Cereb Cortex 17:1139-46. 2007
    ..e., in ACC) between the imagination of pain and the emotion of fear...
  79. ncbi request reprint In vivo studies of phenylalanine hydroxylase by phenylalanine breath test: diagnosis of tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency
    Yoshiyuki Okano
    Department of Pediatrics, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Pediatr Res 56:714-9. 2004
    ..The phenylalanine breath test is useful for the diagnosis of BH4-responsive PAH deficiency and determination of the optimal dosage of BH4 without increasing blood phenylalanine level...
  80. ncbi request reprint Is temporal slow wave on EEG a useful diagnostic tool in vascular depression?
    Eishi Motomura
    Psychiatry Clin Neurosci 57:610-1. 2003