Research Topics
| Yushi InoueSummaryAffiliation: National Hospital Organization Country: Japan Publications
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Detail Information
Publications
Photosensitive and nonphotosensitive electronic screen game-induced seizuresY Inoue
National Epilepsy Center, Shizuoka Higashi Hospital, Urushiyama, Japan
Epilepsia 40:8-16. 1999..To disclose possible epileptologic differences between photosensitive and nonphotosensitive patients with seizures induced by electronic screen games (ESGs)...
Absence of simple partial seizure in temporal lobe epilepsy: its diagnostic and prognostic significanceY Inoue
National Epilepsy Center, Shizuoka Higashi Hospital, Japan
Epilepsy Res 38:133-8. 2000..The surgical outcome in patients without SPS is similar to that in patients with SPS...
Psychiatric disorders before and after surgery for epilepsyY Inoue
Epilepsia 42:13-8. 2001..To examine the frequency of psychiatric disorders before and after surgery for epilepsy and the postoperative changes...
Epilepsy and driving in JapanYushi Inoue
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Epilepsia 45:1630-5. 2004..The driving regulations in Japan were amended in 2002, which lifted the absolute ban on driving by persons with epilepsy (PWE) and granted licenses to PWE after a 2-year seizure-free period...
Uneven interhemispheric connections between left and right primary sensori-motor areasKiyohito Terada
Department of Neurology, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Aoi ku, Shizuoka 420 8688, Japan
Hum Brain Mapp 33:14-26. 2012..Both f-MA and nf-MA send dense interhemispheric connections to the contralateral f-MA. SA may have no or only rare direct connection with the contralateral MA or SA...
Interhemispheric connection of motor areas in humansKiyohito Terada
Department of Neurology, Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Aoi ku, Shizuoka 420 8688, Japan
J Clin Neurophysiol 25:351-6. 2008..The interhemispheric transit time is indicated. The homotopic distribution of the responses indicates that motor coordination of the bilateral bodies is, at least partially, controlled within MC...
Very high-frequency oscillations (over 1000 Hz) of somatosensory-evoked potentials directly recorded from the human brainYuji Sakura
Department of Clinical Laboratory, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
J Clin Neurophysiol 26:414-21. 2009..In this study, at least three components of HFO could be identified. Only very HFO was localized around primary sensory areas, suggesting a possibility that very HFO may provide an effective method of identifying the central sulcus...
Neural connection between bilateral basal temporal regions: cortico-cortical evoked potential analysis in patients with temporal lobe epilepsyShuichi Umeoka
Department of Neurological Surgery, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Urushiyama, Shizuoka, Japan
Neurosurgery 64:847-55; discussion 855. 2009..Some previous studies, however, have suggested that interhemispheric connections between bilateral basal temporal regions (BTR) might have a significant role in propagation of epileptic activities...
Early seizure propagation from the occipital lobe to medial temporal structures and its surgical implicationNaotaka Usui
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Epileptic Disord 10:260-5. 2008..Intracranial EEG revealed very early involvement of the medial temporal lobe in some seizures. Seizure control was achieved without resection of the medial temporal structures...
Posterior cortex epilepsy secondary to ulegyria: is it a surgically remediable syndrome?Naotaka Usui
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Epilepsia 49:1998-2007. 2008..To examine whether surgery is indicated for posterior cortex epilepsy secondary to ulegyria...
Very high frequency oscillations (over 1000 Hz) in human epilepsyNaotaka Usui
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Clin Neurophysiol 121:1825-31. 2010..We describe the characteristics of VHFO, and discuss their underlying mechanism and clinical significance...
Generators of tibial nerve somatosensory evoked potential: recorded from the mesial surface of the human brain using subdural electrodesKiyohito Terada
Department of Neurology, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Aoi ku, Shizuoka, Japan
J Clin Neurophysiol 26:13-6. 2009....
Extraoperative functional mapping of motor areas in epileptic patients by high-frequency cortical stimulationNaotaka Usui
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
J Neurosurg 109:605-14. 2008....
Bilateral symmetric tonic posturing suggesting propagation to the supplementary motor area in a patient with precuneate cortical dysplasiaShuichi Umeoka
Department of Neurological Surgery, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Epileptic Disord 9:443-8. 2007..MRI and invasive EEG confirmed the epileptogenic focus as a precuneate cortical dysplasia lesion.[Published with video sequences]...
Clinical significance of ictal high frequency oscillations in medial temporal lobe epilepsyNaotaka Usui
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Clin Neurophysiol 122:1693-700. 2011..To clarify the clinical significance of ictal high frequency oscillations (HFO) in the medial temporal lobe...
Versive seizures in occipital lobe epilepsy: lateralizing value and pathophysiologyNaotaka Usui
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Aoi ku, Shizuoka, Japan
Epilepsy Res 97:157-61. 2011..Since versive seizures were accompanied by partial somatomotor manifestations in less than half of the patients, it is suggested that the mechanism of version in occipital lobe epilepsy is different from that in frontal lobe epilepsy...
Intracranial EEG findings in patients with lesional lateral temporal lobe epilepsyNaotaka Usui
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Urushiyama, Shizuoka, Japan
Epilepsy Res 78:82-91. 2008..We analyzed the intracranial EEG of cases with localized lesion in the lateral temporal cortex...
Epileptic negative myoclonus: a combined study of EEG and [123I]iomazenil (123I-IMZ) single photon emission computed tomography indicating involvement of medial frontal areaKeiko Usui
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Epilepsy Res 89:220-6. 2010..Combined use of the two methods provided high resolution both in spatial and temporal domain...
Self-induced seizures presumably by peri-orbital somatosensory self-stimulation: a report of two casesRumiko Takayama
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Aoiku, Shizuoka, Japan
Brain Dev 34:685-90. 2012..In patients with serial seizures preceded by peculiar behaviors, we need to consider the possibility of self-induced seizures, even if they have a history of West syndrome and severe psychomotor retardation...
Cutaneous adverse drug reaction in patients with epilepsy after acute encephalitisYukiko Mogami
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Japan
Brain Dev 34:496-503. 2012..RANTES may be a biomarker for susceptibility to CARs in EAE patients...
Lamotrigine is favourable for startle-induced seizuresHiroko Ikeda
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Epileptic Disord 13:277-83. 2011..The addition of LTG treatment dramatically improved the lives of the patients presented here and should be considered as an option for startle-induced seizures...
Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndromeDezhi Cao
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Epilepsia 53:1140-5. 2012..Then we assessed the efficacy of stiripentol (STP) monotherapy versus STP and clobazam (CLB) combination therapy to prevent hyperthermia-induced seizures in Scn1a(RX/+) mice...
Ear movement induced by electrical cortical stimulationLu Yu
Department of Neurology, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Aoi ku, Shizuoka, Japan
Epilepsy Behav 18:488-90. 2010..No other body movements or auditory symptoms were elicited. A possible mechanism underlying this rare phenomenon is discussed...
Magnetoencephalographic correlates of different types of aura in temporal lobe epilepsyKenjiro Fukao
Shizuoka Institute of Epilepsy and Neurological Disorders, Aoi ku, Shizuoka City, Japan
Epilepsia 51:1846-51. 2010..To estimate magnetoencephalography (MEG) correlates of different types of aura in temporal lobe epilepsy (TLE)...
Temporal changes in brain MRI findings in Rasmussen syndromeEtsuko Yamazaki
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Epileptic Disord 13:229-39. 2011..In the present study, we examined the status and evolutionary changes in MRI lesions to identify the MRI characteristics of RS...
Influence of concomitant antiepileptic drugs on plasma lamotrigine concentration in adult Japanese epilepsy patientsYoshiaki Yamamoto
Department of Clinical Research, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Japan
Biol Pharm Bull 35:487-93. 2012..94, 0.94, 0.90, and 0.91, respectively. In the clinical setting, these findings can help to estimate LTG concentrations and predict the inducing or inhibiting effects of concomitant AEDs...
Usefulness of 123I-iomazenil single-photon emission computed tomography in discriminating between mesial and lateral temporal lobe epilepsy in patients in whom magnetic resonance imaging demonstrates normal findingsShuichi Umeoka
Department of Neurological Surgery, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Urushiyama, Shizuoka, Japan
J Neurosurg 107:352-63. 2007....
[Symptoms and clinical course of epilepsy with myoclonic absences]Hiroko Ikeda
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka
No To Hattatsu 43:14-8. 2011..Patients with long MA duration or MA status epilepticus were prone to be refractory to medication. EMA can be divided into two subgroups based on the seizure outcome, favorable and unfavorable. Further large-scale study is required...
Postictal mania versus postictal psychosis: differences in clinical features, epileptogenic zone, and brain functional changes during postictal periodTakuji Nishida
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Epilepsia 47:2104-14. 2006..To clarify the differences between postictal mania (PIM) and postictal psychosis (PIP)...
A homozygous mutation of voltage-gated sodium channel β(I) gene SCN1B in a patient with Dravet syndromeIkuo Ogiwara
Laboratory for Neurogenetics, RIKEN Brain Science Institute, Wako, Saitama, Japan Department of Pediatrics, Tohoku University School of Medicine, Sendai, Miyagi, Japan National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Epilepsia 53:e200-3. 2012..In the cohort, we found one additional homozygous mutation (p.Ile106Phe) in a patient with Dravet syndrome. The identified homozygous SCN1B mutations indicate that SCN1B is an etiologic candidate underlying Dravet syndrome...
Risk factors for hyperammonemia associated with valproic acid therapy in adult epilepsy patientsYoshiaki Yamamoto
Department of Clinical Research, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, 886, Urushiyama, Aoi ku, Shizuoka shi, Shizuoka 420 8688 Japan
Epilepsy Res 101:202-9. 2012..5). Regimens containing multiple inducers were associated with an increased risk of hyperammonemia. Identification of risk factors for hyperammonemia associated with VPA therapy can help to minimize side effects during its clinical use...
Electroclinical features of epilepsy in patients with juvenile type dentatorubral-pallidoluysian atrophyKiyoshi Egawa
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Epilepsia 49:2041-9. 2008..To clarify the electroclinical characteristics of epileptic seizures in patients with juvenile type dentatorubral-pallidoluysian atrophy (DRPLA)...
Diagnostic approach for studying epileptic seizureKeiko Usui
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders
Rinsho Shinkeigaku 52:857-60. 2012..Representative visual examples of symptoms together with the detailed medical knowledge will greatly enhance the capability of diagnosis, the effectiveness of treatment, and help develop clinical strategies...
Stiripentol open study in Japanese patients with Dravet syndromeYushi Inoue
Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
Epilepsia 50:2362-8. 2009..To survey the treatment situation of Dravet syndrome in Japan and to compare this result with effectiveness of stiripentol (STP) add-on therapy in an open-label multicenter study...
[Social aspect of epilepsy]Yushi Inoue
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders
Rinsho Shinkeigaku 47:787-9. 2007..The driving license was issued officially to about 2000 PWE in a year that may contribute to the social integration of PWE...
[Treatment guidelines for epilepsy]Yushi Inoue
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Shizuoka-shi, Shizuoka 420-8688, Japan
No To Shinkei 57:195-201. 2005
Mutations of sodium channel alpha subunit type 1 (SCN1A) in intractable childhood epilepsies with frequent generalized tonic-clonic seizuresTateki Fujiwara
National Epilepsy Centre, Shizuoka Medical Institute of Neurological Disorders, Shizuoka, Japan
Brain 126:531-46. 2003..Here we suggest that SMEI and ICEGTC represent a continuum with minor phenotypic and genotypic differences...
[Treatment guidelines for adult epilepsy]Yushi Inoue
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders
Rinsho Shinkeigaku 44:861-4. 2004..We proposed practical guidelines for treatment of patients with adult epilepsy, including rehabilitation and care for improvement of quality of life...
Dystonic posturing associated with putaminal hyperperfusion depicted on subtraction SPECTMasahiro Mizobuchi
Department of Neurology, Nakamura Memorial Hospital, Sapporo, Japan
Epilepsia 45:948-53. 2004..We evaluated the ictal hyperperfusional areas in patients with DP by using ictal-interictal subtraction single-photon emission computed tomography (SPECT)...
Role of primary sensorimotor cortex and supplementary motor area in volitional swallowing: a movement-related cortical potential studyTakeshi Satow
Dept. of Neurology, Kyoto Univ. Graduate School of Medicine, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan
Am J Physiol Gastrointest Liver Physiol 287:G459-70. 2004..SMA plays a supplementary role to face/tongue SMI both in swallowing and tongue movements...
Patients with a sodium channel alpha 1 gene mutation show wide phenotypic variationHitoshi Osaka
Division of Neurology, Kanagawa Children s Medical Center, Yokohama 232 8555, Japan
Epilepsy Res 75:46-51. 2007..Unidentified modifiers may play critical roles in determining the ultimate phenotype of patients with sodium channel mutations...
A Kv4.2 truncation mutation in a patient with temporal lobe epilepsyBaljinder Singh
Laboratory for Neurogenetics, RIKEN Brain Science Institute, Saitama 351 0198, Japan
Neurobiol Dis 24:245-53. 2006..Our observations, together with other lines of evidence, raise the intriguing possibility of a role for KCND2 in the etiology of TLE...
A nonsense mutation of the sodium channel gene SCN2A in a patient with intractable epilepsy and mental declineKazusaku Kamiya
Laboratory for Neurogenetics, RIKEN Brain Science Institute, Saitama 351 0198, Japan
J Neurosci 24:2690-8. 2004..2 protein is one plausible explanation for the pathology of this patient; however, our biophysical findings suggest that the R102X truncated protein exerts a dominant negative effect leading to the patient's intractable epilepsy...
Mutational analysis of CACNA1G in idiopathic generalized epilepsy. Mutation in brief #962. OnlineBaljinder Singh
Laboratory for Neurogenetics, RIKEN Brain Science Institute, Saitama, Japan
Hum Mutat 28:524-5. 2007..Our collective findings flag CACNA1G as a potential susceptibility locus for IGE subsyndromes that warrants closer investigation...
Mutations in the NHLRC1 gene are the common cause for Lafora disease in the Japanese populationShweta Singh
Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India
J Hum Genet 50:347-52. 2005..Our study, in addition to documenting the genetic and molecular heterogeneity observed for LD, suggests that mutations in the NHLRC1 gene may be a common cause of LD in the Japanese population...
Visual reflex seizures induced by complex stimuliBenjamin G Zifkin
Epilepsy Clinic, Montreal Neurological Hospital, , , , Montreal, Quebec, Canada
Epilepsia 45:27-9. 2004..Nonspecific factors such as sleep deprivation, prolonged exposure, and drug or alcohol use also may play a role in reflex seizure occurrence...
