Yushi Inoue

Summary

Affiliation: National Hospital Organization
Country: Japan

Publications

  1. ncbi request reprint Photosensitive and nonphotosensitive electronic screen game-induced seizures
    Y Inoue
    National Epilepsy Center, Shizuoka Higashi Hospital, Urushiyama, Japan
    Epilepsia 40:8-16. 1999
  2. ncbi request reprint Epilepsy and driving in Japan
    Yushi Inoue
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epilepsia 45:1630-5. 2004
  3. ncbi request reprint Psychiatric disorders before and after surgery for epilepsy
    Y Inoue
    Epilepsia 42:13-8. 2001
  4. ncbi request reprint Absence of simple partial seizure in temporal lobe epilepsy: its diagnostic and prognostic significance
    Y Inoue
    National Epilepsy Center, Shizuoka Higashi Hospital, Japan
    Epilepsy Res 38:133-8. 2000
  5. doi request reprint Uneven interhemispheric connections between left and right primary sensori-motor areas
    Kiyohito Terada
    Department of Neurology, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Aoi ku, Shizuoka 420 8688, Japan
    Hum Brain Mapp 33:14-26. 2012
  6. doi request reprint Very high-frequency oscillations (over 1000 Hz) of somatosensory-evoked potentials directly recorded from the human brain
    Yuji Sakura
    Department of Clinical Laboratory, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    J Clin Neurophysiol 26:414-21. 2009
  7. doi request reprint Interhemispheric connection of motor areas in humans
    Kiyohito Terada
    Department of Neurology, Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Aoi ku, Shizuoka 420 8688, Japan
    J Clin Neurophysiol 25:351-6. 2008
  8. doi request reprint Neural connection between bilateral basal temporal regions: cortico-cortical evoked potential analysis in patients with temporal lobe epilepsy
    Shuichi Umeoka
    Department of Neurological Surgery, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Urushiyama, Shizuoka, Japan
    Neurosurgery 64:847-55; discussion 855. 2009
  9. doi request reprint Early seizure propagation from the occipital lobe to medial temporal structures and its surgical implication
    Naotaka Usui
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epileptic Disord 10:260-5. 2008
  10. doi request reprint Risk factors for hyperammonemia in pediatric patients with epilepsy
    Yoshiaki Yamamoto
    Department of Clinical Research, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epilepsia 54:983-9. 2013

Collaborators

Detail Information

Publications57

  1. ncbi request reprint Photosensitive and nonphotosensitive electronic screen game-induced seizures
    Y Inoue
    National Epilepsy Center, Shizuoka Higashi Hospital, Urushiyama, Japan
    Epilepsia 40:8-16. 1999
    ..To disclose possible epileptologic differences between photosensitive and nonphotosensitive patients with seizures induced by electronic screen games (ESGs)...
  2. ncbi request reprint Epilepsy and driving in Japan
    Yushi Inoue
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epilepsia 45:1630-5. 2004
    ..The driving regulations in Japan were amended in 2002, which lifted the absolute ban on driving by persons with epilepsy (PWE) and granted licenses to PWE after a 2-year seizure-free period...
  3. ncbi request reprint Psychiatric disorders before and after surgery for epilepsy
    Y Inoue
    Epilepsia 42:13-8. 2001
    ..To examine the frequency of psychiatric disorders before and after surgery for epilepsy and the postoperative changes...
  4. ncbi request reprint Absence of simple partial seizure in temporal lobe epilepsy: its diagnostic and prognostic significance
    Y Inoue
    National Epilepsy Center, Shizuoka Higashi Hospital, Japan
    Epilepsy Res 38:133-8. 2000
    ..The surgical outcome in patients without SPS is similar to that in patients with SPS...
  5. doi request reprint Uneven interhemispheric connections between left and right primary sensori-motor areas
    Kiyohito Terada
    Department of Neurology, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Aoi ku, Shizuoka 420 8688, Japan
    Hum Brain Mapp 33:14-26. 2012
    ..Both f-MA and nf-MA send dense interhemispheric connections to the contralateral f-MA. SA may have no or only rare direct connection with the contralateral MA or SA...
  6. doi request reprint Very high-frequency oscillations (over 1000 Hz) of somatosensory-evoked potentials directly recorded from the human brain
    Yuji Sakura
    Department of Clinical Laboratory, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    J Clin Neurophysiol 26:414-21. 2009
    ..In this study, at least three components of HFO could be identified. Only very HFO was localized around primary sensory areas, suggesting a possibility that very HFO may provide an effective method of identifying the central sulcus...
  7. doi request reprint Interhemispheric connection of motor areas in humans
    Kiyohito Terada
    Department of Neurology, Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Aoi ku, Shizuoka 420 8688, Japan
    J Clin Neurophysiol 25:351-6. 2008
    ..The interhemispheric transit time is indicated. The homotopic distribution of the responses indicates that motor coordination of the bilateral bodies is, at least partially, controlled within MC...
  8. doi request reprint Neural connection between bilateral basal temporal regions: cortico-cortical evoked potential analysis in patients with temporal lobe epilepsy
    Shuichi Umeoka
    Department of Neurological Surgery, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Urushiyama, Shizuoka, Japan
    Neurosurgery 64:847-55; discussion 855. 2009
    ..Some previous studies, however, have suggested that interhemispheric connections between bilateral basal temporal regions (BTR) might have a significant role in propagation of epileptic activities...
  9. doi request reprint Early seizure propagation from the occipital lobe to medial temporal structures and its surgical implication
    Naotaka Usui
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epileptic Disord 10:260-5. 2008
    ..Intracranial EEG revealed very early involvement of the medial temporal lobe in some seizures. Seizure control was achieved without resection of the medial temporal structures...
  10. doi request reprint Risk factors for hyperammonemia in pediatric patients with epilepsy
    Yoshiaki Yamamoto
    Department of Clinical Research, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epilepsia 54:983-9. 2013
    ..To identify risk factors for hyperammonemia in pediatric patients with epilepsy...
  11. doi request reprint Generators of tibial nerve somatosensory evoked potential: recorded from the mesial surface of the human brain using subdural electrodes
    Kiyohito Terada
    Department of Neurology, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Aoi ku, Shizuoka, Japan
    J Clin Neurophysiol 26:13-6. 2009
    ....
  12. ncbi request reprint Posterior cortex epilepsy secondary to ulegyria: is it a surgically remediable syndrome?
    Naotaka Usui
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epilepsia 49:1998-2007. 2008
    ..To examine whether surgery is indicated for posterior cortex epilepsy secondary to ulegyria...
  13. doi request reprint Very high frequency oscillations (over 1000 Hz) in human epilepsy
    Naotaka Usui
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Clin Neurophysiol 121:1825-31. 2010
    ..We describe the characteristics of VHFO, and discuss their underlying mechanism and clinical significance...
  14. doi request reprint Extraoperative functional mapping of motor areas in epileptic patients by high-frequency cortical stimulation
    Naotaka Usui
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    J Neurosurg 109:605-14. 2008
    ....
  15. doi request reprint Clinical significance of ictal high frequency oscillations in medial temporal lobe epilepsy
    Naotaka Usui
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Clin Neurophysiol 122:1693-700. 2011
    ..To clarify the clinical significance of ictal high frequency oscillations (HFO) in the medial temporal lobe...
  16. ncbi request reprint Bilateral symmetric tonic posturing suggesting propagation to the supplementary motor area in a patient with precuneate cortical dysplasia
    Shuichi Umeoka
    Department of Neurological Surgery, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epileptic Disord 9:443-8. 2007
    ..MRI and invasive EEG confirmed the epileptogenic focus as a precuneate cortical dysplasia lesion.[Published with video sequences]...
  17. doi request reprint Versive seizures in occipital lobe epilepsy: lateralizing value and pathophysiology
    Naotaka Usui
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Aoi ku, Shizuoka, Japan
    Epilepsy Res 97:157-61. 2011
    ..Since versive seizures were accompanied by partial somatomotor manifestations in less than half of the patients, it is suggested that the mechanism of version in occipital lobe epilepsy is different from that in frontal lobe epilepsy...
  18. ncbi request reprint Intracranial EEG findings in patients with lesional lateral temporal lobe epilepsy
    Naotaka Usui
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Urushiyama, Shizuoka, Japan
    Epilepsy Res 78:82-91. 2008
    ..We analyzed the intracranial EEG of cases with localized lesion in the lateral temporal cortex...
  19. doi request reprint Epileptic negative myoclonus: a combined study of EEG and [123I]iomazenil (123I-IMZ) single photon emission computed tomography indicating involvement of medial frontal area
    Keiko Usui
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epilepsy Res 89:220-6. 2010
    ..Combined use of the two methods provided high resolution both in spatial and temporal domain...
  20. doi request reprint Influence of CYP2C19 polymorphism and concomitant antiepileptic drugs on serum clobazam and N-desmethyl clobazam concentrations in patients with epilepsy
    Yoshiaki Yamamoto
    Department of Clinical Research, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Ulushiyama, Aoi ku, Japan
    Ther Drug Monit 35:305-12. 2013
    ....
  21. doi request reprint Cutaneous adverse drug reaction in patients with epilepsy after acute encephalitis
    Yukiko Mogami
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Japan
    Brain Dev 34:496-503. 2012
    ..RANTES may be a biomarker for susceptibility to CARs in EAE patients...
  22. doi request reprint Self-induced seizures presumably by peri-orbital somatosensory self-stimulation: a report of two cases
    Rumiko Takayama
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Aoiku, Shizuoka, Japan
    Brain Dev 34:685-90. 2012
    ..In patients with serial seizures preceded by peculiar behaviors, we need to consider the possibility of self-induced seizures, even if they have a history of West syndrome and severe psychomotor retardation...
  23. doi request reprint Lamotrigine is favourable for startle-induced seizures
    Hiroko Ikeda
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epileptic Disord 13:277-83. 2011
    ..The addition of LTG treatment dramatically improved the lives of the patients presented here and should be considered as an option for startle-induced seizures...
  24. doi request reprint Immunomodulatory therapy versus surgery for Rasmussen syndrome in early childhood
    Yukitoshi Takahashi
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorder, Shizuoka, Japan
    Brain Dev 35:778-85. 2013
    ..We suggest a new treatment strategy for RS using early immunomodulatory therapy: initiation of regular steroid pulse therapy after early diagnosis indicated by biomarkers, then switching to tacrolimus therapy after several months. ..
  25. ncbi request reprint Mesial temporal lobe epilepsy with no specific histological abnormality: a distinct surgically remediable syndrome
    Naotaka Usui
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Urushiyama 886, Aoi ku, Shizuoka 420 8688, Japan Electronic address
    Epilepsy Behav 29:542-7. 2013
    ..The purposes of the study were twofold: to clarify the clinical features and surgical outcome of mesial temporal lobe epilepsy (MTLE) with no specific histological abnormality and to determine the optimal surgical strategy...
  26. ncbi request reprint Long-term course of Dravet syndrome: a study from an epilepsy center in Japan
    Rumiko Takayama
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epilepsia 55:528-38. 2014
    ..This study attempted to clarify the long-term course of Dravet syndrome (DS)...
  27. doi request reprint Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndrome
    Dezhi Cao
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epilepsia 53:1140-5. 2012
    ..Then we assessed the efficacy of stiripentol (STP) monotherapy versus STP and clobazam (CLB) combination therapy to prevent hyperthermia-induced seizures in Scn1a(RX/+) mice...
  28. doi request reprint Ear movement induced by electrical cortical stimulation
    Lu Yu
    Department of Neurology, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Aoi ku, Shizuoka, Japan
    Epilepsy Behav 18:488-90. 2010
    ..No other body movements or auditory symptoms were elicited. A possible mechanism underlying this rare phenomenon is discussed...
  29. ncbi request reprint Interaction between sulthiame and clobazam: sulthiame inhibits the metabolism of clobazam, possibly via an action on CYP2C19
    Yoshiaki Yamamoto
    Department of Clinical Research, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Shizuoka 420 8688, Japan Department of Clinical Pharmaceutics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52 1 Yada, Shizuoka 422 8526, Japan Electronic address
    Epilepsy Behav 34:124-6. 2014
    ..During combination therapy with STM and CLB in patients with CYP2C19 intermediate or extensive metabolizer phenotypes, monitoring of DMCLB concentrations may be helpful in ascertaining CLB-related adverse effects...
  30. ncbi request reprint Influence of uridine diphosphate glucuronosyltransferase 2B7 -161C>T polymorphism on the concentration of valproic acid in pediatric epilepsy patients
    Kazuyuki Inoue
    Department of Clinical Pharmacology and Genetics, School of Pharmaceutical Sciences, University of Shizuoka and Department of Clinical Research, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, National Epilepsy Center, Shizuoka, Japan
    Ther Drug Monit 36:406-9. 2014
    ..This study aimed to examine the relationships between plasma VPA concentrations and the -161C>T single nucleotide polymorphism in uridine diphosphate glucuronosyltransferase (UGT) 2B7 genes in pediatric epilepsy patients...
  31. doi request reprint Temporal changes in brain MRI findings in Rasmussen syndrome
    Etsuko Yamazaki
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epileptic Disord 13:229-39. 2011
    ..In the present study, we examined the status and evolutionary changes in MRI lesions to identify the MRI characteristics of RS...
  32. doi request reprint Magnetoencephalographic correlates of different types of aura in temporal lobe epilepsy
    Kenjiro Fukao
    Shizuoka Institute of Epilepsy and Neurological Disorders, Aoi ku, Shizuoka City, Japan
    Epilepsia 51:1846-51. 2010
    ..To estimate magnetoencephalography (MEG) correlates of different types of aura in temporal lobe epilepsy (TLE)...
  33. doi request reprint Genetic variations of immunoregulatory genes associated with Rasmussen syndrome
    Yukitoshi Takahashi
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorder, 886 Urushiyama, Aoi ward, Shizuoka, Japan Department of Pediatrics, Gifu University School of Medicine, Yanagido, Gifu, Japan Electronic address
    Epilepsy Res 107:238-43. 2013
    ..To elucidate the genetic predisposition of Rasmussen syndrome (RS)...
  34. doi request reprint Risk factors for hyperammonemia associated with valproic acid therapy in adult epilepsy patients
    Yoshiaki Yamamoto
    Department of Clinical Research, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, 886, Urushiyama, Aoi ku, Shizuoka shi, Shizuoka 420 8688 Japan
    Epilepsy Res 101:202-9. 2012
    ..5). Regimens containing multiple inducers were associated with an increased risk of hyperammonemia. Identification of risk factors for hyperammonemia associated with VPA therapy can help to minimize side effects during its clinical use...
  35. ncbi request reprint Influence of concomitant antiepileptic drugs on plasma lamotrigine concentration in adult Japanese epilepsy patients
    Yoshiaki Yamamoto
    Department of Clinical Research, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Japan
    Biol Pharm Bull 35:487-93. 2012
    ..94, 0.94, 0.90, and 0.91, respectively. In the clinical setting, these findings can help to estimate LTG concentrations and predict the inducing or inhibiting effects of concomitant AEDs...
  36. ncbi request reprint Usefulness of 123I-iomazenil single-photon emission computed tomography in discriminating between mesial and lateral temporal lobe epilepsy in patients in whom magnetic resonance imaging demonstrates normal findings
    Shuichi Umeoka
    Department of Neurological Surgery, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Urushiyama, Shizuoka, Japan
    J Neurosurg 107:352-63. 2007
    ....
  37. doi request reprint Interstitial duplication of 2q32.1-q33.3 in a patient with epilepsy, developmental delay, and autistic behavior
    Daisuke Usui
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Am J Med Genet A 161:1078-84. 2013
    ..This result is in agreement with our previous study, in which we observed that duplicated segments as interstitial duplications are generally inserted in the tandem configuration...
  38. ncbi request reprint [Symptoms and clinical course of epilepsy with myoclonic absences]
    Hiroko Ikeda
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka
    No To Hattatsu 43:14-8. 2011
    ..Patients with long MA duration or MA status epilepticus were prone to be refractory to medication. EMA can be divided into two subgroups based on the seizure outcome, favorable and unfavorable. Further large-scale study is required...
  39. ncbi request reprint Postictal mania versus postictal psychosis: differences in clinical features, epileptogenic zone, and brain functional changes during postictal period
    Takuji Nishida
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epilepsia 47:2104-14. 2006
    ..To clarify the differences between postictal mania (PIM) and postictal psychosis (PIP)...
  40. ncbi request reprint [Diagnostic approach for studying epileptic seizure]
    Keiko Usui
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders
    Rinsho Shinkeigaku 52:857-60. 2012
    ..Representative visual examples of symptoms together with the detailed medical knowledge will greatly enhance the capability of diagnosis, the effectiveness of treatment, and help develop clinical strategies...
  41. doi request reprint A homozygous mutation of voltage-gated sodium channel β(I) gene SCN1B in a patient with Dravet syndrome
    Ikuo Ogiwara
    Laboratory for Neurogenetics, RIKEN Brain Science Institute, Wako, Saitama, Japan
    Epilepsia 53:e200-3. 2012
    ..In the cohort, we found one additional homozygous mutation (p.Ile106Phe) in a patient with Dravet syndrome. The identified homozygous SCN1B mutations indicate that SCN1B is an etiologic candidate underlying Dravet syndrome...
  42. ncbi request reprint Electroclinical features of epilepsy in patients with juvenile type dentatorubral-pallidoluysian atrophy
    Kiyoshi Egawa
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epilepsia 49:2041-9. 2008
    ..To clarify the electroclinical characteristics of epileptic seizures in patients with juvenile type dentatorubral-pallidoluysian atrophy (DRPLA)...
  43. pmc Bioavailability of intravenous fosphenytoin sodium in healthy Japanese volunteers
    Yushi Inoue
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Eur J Drug Metab Pharmacokinet 38:139-48. 2013
    ..In conclusion, fosphenytoin sodium is considered to be a useful substitute for phenytoin sodium with almost no associated injection-site reactions...
  44. doi request reprint Stiripentol open study in Japanese patients with Dravet syndrome
    Yushi Inoue
    Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
    Epilepsia 50:2362-8. 2009
    ..To survey the treatment situation of Dravet syndrome in Japan and to compare this result with effectiveness of stiripentol (STP) add-on therapy in an open-label multicenter study...
  45. ncbi request reprint Effectiveness of add-on stiripentol to clobazam and valproate in Japanese patients with Dravet syndrome: Additional supportive evidence
    Yushi Inoue
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Urushiyama 886, Aoi ku, Shizuoka 420 8688, Japan Electronic address
    Epilepsy Res 108:725-31. 2014
    ..To evaluate the efficacy and safety of stiripentol as add-on therapy in Japanese patients with Dravet syndrome treated with clobazam (CLB) and valproate (VPA)...
  46. ncbi request reprint [Social aspect of epilepsy]
    Yushi Inoue
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders
    Rinsho Shinkeigaku 47:787-9. 2007
    ..The driving license was issued officially to about 2000 PWE in a year that may contribute to the social integration of PWE...
  47. ncbi request reprint [Treatment guidelines for adult epilepsy]
    Yushi Inoue
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders
    Rinsho Shinkeigaku 44:861-4. 2004
    ..We proposed practical guidelines for treatment of patients with adult epilepsy, including rehabilitation and care for improvement of quality of life...
  48. ncbi request reprint [Treatment guidelines for epilepsy]
    Yushi Inoue
    National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Shizuoka shi, Shizuoka 420 8688, Japan
    No To Shinkei 57:195-201. 2005
  49. ncbi request reprint Mutations of sodium channel alpha subunit type 1 (SCN1A) in intractable childhood epilepsies with frequent generalized tonic-clonic seizures
    Tateki Fujiwara
    National Epilepsy Centre, Shizuoka Medical Institute of Neurological Disorders, Shizuoka, Japan
    Brain 126:531-46. 2003
    ..Here we suggest that SMEI and ICEGTC represent a continuum with minor phenotypic and genotypic differences...
  50. ncbi request reprint Dystonic posturing associated with putaminal hyperperfusion depicted on subtraction SPECT
    Masahiro Mizobuchi
    Department of Neurology, Nakamura Memorial Hospital, Sapporo, Japan
    Epilepsia 45:948-53. 2004
    ..We evaluated the ictal hyperperfusional areas in patients with DP by using ictal-interictal subtraction single-photon emission computed tomography (SPECT)...
  51. ncbi request reprint Role of primary sensorimotor cortex and supplementary motor area in volitional swallowing: a movement-related cortical potential study
    Takeshi Satow
    Dept of Neurology, Kyoto Univ Graduate School of Medicine, Shogoin, Sakyo ku, Kyoto 606 8507, Japan
    Am J Physiol Gastrointest Liver Physiol 287:G459-70. 2004
    ..SMA plays a supplementary role to face/tongue SMI both in swallowing and tongue movements...
  52. ncbi request reprint Mutations in the NHLRC1 gene are the common cause for Lafora disease in the Japanese population
    Shweta Singh
    Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India
    J Hum Genet 50:347-52. 2005
    ..Our study, in addition to documenting the genetic and molecular heterogeneity observed for LD, suggests that mutations in the NHLRC1 gene may be a common cause of LD in the Japanese population...
  53. ncbi request reprint Mutational analysis of CACNA1G in idiopathic generalized epilepsy. Mutation in brief #962. Online
    Baljinder Singh
    Laboratory for Neurogenetics, RIKEN Brain Science Institute, Saitama, Japan
    Hum Mutat 28:524-5. 2007
    ..Our collective findings flag CACNA1G as a potential susceptibility locus for IGE subsyndromes that warrants closer investigation...
  54. ncbi request reprint A nonsense mutation of the sodium channel gene SCN2A in a patient with intractable epilepsy and mental decline
    Kazusaku Kamiya
    Laboratory for Neurogenetics, RIKEN Brain Science Institute, Saitama 351 0198, Japan
    J Neurosci 24:2690-8. 2004
    ..2 protein is one plausible explanation for the pathology of this patient; however, our biophysical findings suggest that the R102X truncated protein exerts a dominant negative effect leading to the patient's intractable epilepsy...
  55. ncbi request reprint Visual reflex seizures induced by complex stimuli
    Benjamin G Zifkin
    Epilepsy Clinic, Montreal Neurological Hospital, and Faculté de Médicine, Universite de Montreal, Hôpital du Sacré Coeur, Montreal, Quebec, Canada
    Epilepsia 45:27-9. 2004
    ..Nonspecific factors such as sleep deprivation, prolonged exposure, and drug or alcohol use also may play a role in reflex seizure occurrence...
  56. ncbi request reprint Patients with a sodium channel alpha 1 gene mutation show wide phenotypic variation
    Hitoshi Osaka
    Division of Neurology, Kanagawa Children s Medical Center, Yokohama 232 8555, Japan
    Epilepsy Res 75:46-51. 2007
    ..Unidentified modifiers may play critical roles in determining the ultimate phenotype of patients with sodium channel mutations...
  57. ncbi request reprint A Kv4.2 truncation mutation in a patient with temporal lobe epilepsy
    Baljinder Singh
    Laboratory for Neurogenetics, RIKEN Brain Science Institute, Saitama 351 0198, Japan
    Neurobiol Dis 24:245-53. 2006
    ..Our observations, together with other lines of evidence, raise the intriguing possibility of a role for KCND2 in the etiology of TLE...