M Inoue

Summary

Affiliation: National Cancer Center
Country: Japan

Publications

  1. pmc Green tea drinking and subsequent risk of breast cancer in a population-based cohort of Japanese women
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Breast Cancer Res 12:R88. 2010
  2. doi request reprint Insulin resistance and cancer: epidemiological evidence
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tsukiji, Chuo Ku, Tokyo Japan
    Endocr Relat Cancer 19:F1-8. 2012
  3. doi request reprint Attributable causes of cancer in Japan in 2005--systematic assessment to estimate current burden of cancer attributable to known preventable risk factors in Japan
    M Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Oncol 23:1362-9. 2012
  4. doi request reprint Impact of alcohol intake on total mortality and mortality from major causes in Japan: a pooled analysis of six large-scale cohort studies
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Epidemiol Community Health 66:448-56. 2012
  5. doi request reprint Metabolic factors and subsequent risk of hepatocellular carcinoma by hepatitis virus infection status: a large-scale population-based cohort study of Japanese men and women (JPHC Study Cohort II)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Causes Control 20:741-50. 2009
  6. doi request reprint Impact of metabolic factors on subsequent cancer risk: results from a large-scale population-based cohort study in Japan
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, International Medical Center of Japan, Tokyo, Japan
    Eur J Cancer Prev 18:240-7. 2009
  7. doi request reprint Green tea consumption and gastric cancer in Japanese: a pooled analysis of six cohort studies
    M Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045 Japan
    Gut 58:1323-32. 2009
  8. doi request reprint Daily total physical activity level and premature death in men and women: results from a large-scale population-based cohort study in Japan (JPHC study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 18:522-30. 2008
  9. doi request reprint Validity of self-reported cancer among a Japanese population: recent results from a population-based prospective study in Japan (JPHC Study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol 35:250-3. 2011
  10. doi request reprint Effect of coffee and green tea consumption on the risk of liver cancer: cohort analysis by hepatitis virus infection status
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 18:1746-53. 2009

Collaborators

Detail Information

Publications63

  1. pmc Green tea drinking and subsequent risk of breast cancer in a population-based cohort of Japanese women
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Breast Cancer Res 12:R88. 2010
    ....
  2. doi request reprint Insulin resistance and cancer: epidemiological evidence
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tsukiji, Chuo Ku, Tokyo Japan
    Endocr Relat Cancer 19:F1-8. 2012
    ..Interventions directed at or involving these variables should contribute to decreasing the risk of insulin resistance-associated cancer...
  3. doi request reprint Attributable causes of cancer in Japan in 2005--systematic assessment to estimate current burden of cancer attributable to known preventable risk factors in Japan
    M Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Oncol 23:1362-9. 2012
    ..To contribute to evidence-based policy decision making for national cancer control, we conducted a systematic assessment to estimate the current burden of cancer attributable to known preventable risk factors in Japan in 2005...
  4. doi request reprint Impact of alcohol intake on total mortality and mortality from major causes in Japan: a pooled analysis of six large-scale cohort studies
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Epidemiol Community Health 66:448-56. 2012
    ....
  5. doi request reprint Metabolic factors and subsequent risk of hepatocellular carcinoma by hepatitis virus infection status: a large-scale population-based cohort study of Japanese men and women (JPHC Study Cohort II)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Causes Control 20:741-50. 2009
    ..We prospectively examined whether metabolic factors predicts the subsequent risk of HCC in the Japan Public Health Center-based Prospective Study Cohort II, in consideration of hepatitis virus infection status...
  6. doi request reprint Impact of metabolic factors on subsequent cancer risk: results from a large-scale population-based cohort study in Japan
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, International Medical Center of Japan, Tokyo, Japan
    Eur J Cancer Prev 18:240-7. 2009
    ..21-2.55). Metabolic factors in the aggregate may have little impact on total cancer risk in the Japanese population, although the association between specific components and specific cancers suggests an etiologic link between them...
  7. doi request reprint Green tea consumption and gastric cancer in Japanese: a pooled analysis of six cohort studies
    M Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045 Japan
    Gut 58:1323-32. 2009
    ..Previous experimental studies have suggested many possible anti-cancer mechanisms for green tea, but epidemiological evidence for the effect of green tea consumption on gastric cancer risk is conflicting...
  8. doi request reprint Daily total physical activity level and premature death in men and women: results from a large-scale population-based cohort study in Japan (JPHC study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 18:522-30. 2008
    ..We prospectively examined the association between daily total physical activity level (METs/day) and subsequent risk of all-cause mortality and mortalities from cancer, heart disease, and cerebrovascular disease...
  9. doi request reprint Validity of self-reported cancer among a Japanese population: recent results from a population-based prospective study in Japan (JPHC Study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol 35:250-3. 2011
    ..Self-reported diagnoses of cancer do not provide sufficient accuracy for the detection and classification of incident cancers. Our findings may be extrapolated to other Japanese populations...
  10. doi request reprint Effect of coffee and green tea consumption on the risk of liver cancer: cohort analysis by hepatitis virus infection status
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 18:1746-53. 2009
    ..Our results suggest that coffee consumption may reduce the risk of liver cancer regardless of HCV and HBV infection status, whereas green tea may not reduce this risk..
  11. ncbi request reprint Impact of lifestyle on overall cancer risk among Japanese: the Japan Public Health Center-based Prospective Study (JPHC Study)
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Epidemiol 20:90-6. 2010
    ..Although people with a history of diabetes may be at increased risk of cancer, extreme body mass index and metabolic factors in the aggregate had little impact on overall cancer risk in the Japanese population...
  12. doi request reprint Daily total physical activity level and total cancer risk in men and women: results from a large-scale population-based cohort study in Japan
    Manami Inoue
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Epidemiol 168:391-403. 2008
    ..By site, decreased risks were observed for cancers of the colon, liver, and pancreas in men and for cancer of the stomach in women. Increased daily physical activity may be beneficial in preventing cancer in a relatively lean population...
  13. doi request reprint Body weight at age 20 years, subsequent weight change and breast cancer risk defined by estrogen and progesterone receptor status--the Japan public health center-based prospective study
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 129:1214-24. 2011
    ..50-3.34)]. Low BMI at age 20 years was substantially associated with an increased risk of breast cancer. In contrast, high recent BMI and subsequent BMI gain from age 20 were associated with increased risk of postmenopausal ER+PR+ tumors...
  14. doi request reprint Alcohol and risk of lung cancer among Japanese men: data from a large-scale population-based cohort study, the JPHC study
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Causes Control 19:1095-102. 2008
    ..Here, we investigated the association between alcohol consumption and lung cancer incidence...
  15. doi request reprint 10-Year risk of colorectal cancer: development and validation of a prediction model in middle-aged Japanese men
    Enbo Ma
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Cancer Epidemiol 34:534-41. 2010
    ..As fewer studies on cancer risk prediction were seen so far, we initially developed an assessment tool with synthesizing key information from a variety of CRC risk factors through a large population-based cohort study...
  16. doi request reprint Body mass index and subsequent risk of kidney cancer: a prospective cohort study in Japan
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Ann Epidemiol 20:466-72. 2010
    ..Herein, we investigate the association between body mass index (BMI) and kidney cancer risk in Japanese persons, a relatively lean population...
  17. doi request reprint Calcium, vitamin D and dairy intake in relation to type 2 diabetes risk in a Japanese cohort
    K Kirii
    Department of Epidemiology and International Health, Research Institute, International Medical Center of Japan, Tokyo, Japan
    Diabetologia 52:2542-50. 2009
    ..Calcium and vitamin D have been implicated in the development of type 2 diabetes, but epidemiological evidence is limited. We examined prospectively the relation of calcium and vitamin D intake to type 2 diabetes risk in a Japanese cohort...
  18. doi request reprint Female reproductive factors and the risk of gastric cancer in a large-scale population-based cohort study in Japan (JPHC study)
    Christina Persson
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 17:345-53. 2008
    ..Although early estrogen exposure may have some protective effect, female reproductive factors may have no substantial influence on gastric cancer development...
  19. pmc Use of vitamin supplements and risk of total cancer and cardiovascular disease among the Japanese general population: a population-based survey
    Azusa Hara
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo 104 0045, Japan
    BMC Public Health 11:540. 2011
    ..We examined whether vitamin supplement use patterns affect cancer and CVD risk in a population-based cohort study in Japan...
  20. doi request reprint Coffee, green tea, and caffeine consumption and subsequent risk of bladder cancer in relation to smoking status: a prospective study in Japan
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer Sci 100:294-91. 2009
    ..15–3.66), respectively. In conclusion, cigarette smoking was confirmed as a risk factor for bladder cancer. Coffee and caffeine may be associated with an increased bladder cancer risk in never or former smokers among Japanese men...
  21. doi request reprint Isoflavone consumption and subsequent risk of hepatocellular carcinoma in a population-based prospective cohort of Japanese men and women
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 124:1644-9. 2009
    ..Women with hepatitis virus infection may be advised to abstain from isoflavone consumption. Further studies are warranted to confirm these findings...
  22. doi request reprint Leisure-time physical activity and breast cancer risk defined by estrogen and progesterone receptor status--the Japan Public Health Center-based Prospective Study
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Tokyo, 104 0045, Japan
    Prev Med 52:227-33. 2011
    ..The study aims to investigate the association between leisure-time physical activity and breast cancer risk in consideration of tumor estrogen-receptor/progesterone-receptor status...
  23. pmc Vegetable, fruit and antioxidant nutrient consumption and subsequent risk of hepatocellular carcinoma: a prospective cohort study in Japan
    N Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center 5 1 1, Tsukiji Chuo ku, Tokyo 104 0045, Japan
    Br J Cancer 100:181-4. 2009
    ..61 (95% confidence interval (CI)=0.36-1.03, P(trend)=0.07), 0.65 (95% CI=0.39-1.08, P(trend)=0.06) and 0.59 (95% CI=0.35-1.01, P(trend)=0.04), respectively...
  24. doi request reprint Coffee consumption and risk of endometrial cancer: a prospective study in Japan
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 123:2406-10. 2008
    ..Coffee consumption may be associated with a decreased risk of endometrial cancer...
  25. doi request reprint Serum aminotransferase level and the risk of hepatocellular carcinoma: a population-based cohort study in Japan
    Seiji Ishiguro
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 18:26-32. 2009
    ..This finding indicates that ALT level is a good independent determinant of the need for intervention. Clinical application of these findings may help decrease HCC-associated mortality in hepatitis virus-endemic regions...
  26. doi request reprint Reproductive factors, exogenous female hormone use and colorectal cancer risk: the Japan Public Health Center-based Prospective Study
    Munira Akhter
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Eur J Cancer Prev 17:515-24. 2008
    ..59). In contrast, no statistically significant association was found for rectal cancer. These findings suggest that late age at first birth is associated with a reduced risk of colon cancer in postmenopausal Japanese women...
  27. doi request reprint Effect of alcohol consumption, cigarette smoking and flushing response on esophageal cancer risk: a population-based cohort study (JPHC study)
    Seiji Ishiguro
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Lett 275:240-6. 2009
    ..10-5.51). Strong effect modification was detected in heavy smokers. Our results suggest that heavy alcohol consumption together with heavy smoking may increase the risk of ESCC particularly in individuals with the flushing response...
  28. doi request reprint Impact of viral load of hepatitis C on the incidence of hepatocellular carcinoma: A population-based cohort study (JPHC Study)
    Seiji Ishiguro
    National Cancer Center, Tokyo, Japan
    Cancer Lett 300:173-9. 2011
    ..The risk was 3.86-fold higher (CI; 1.73-8.62) for genotype 1 than genotype 2. Our findings suggest that HCV viremia strongly influences the occurrence of hepatocellular carcinoma without titer-dependence...
  29. doi request reprint High dietary intake of magnesium may decrease risk of colorectal cancer in Japanese men
    Enbo Ma
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    J Nutr 140:779-85. 2010
    ..There were no significant associations between magnesium intake and cancer risk in women. Higher dietary intake of magnesium may decrease the risk of CRC in Japanese men...
  30. doi request reprint Dairy product, saturated fatty acid, and calcium intake and prostate cancer in a prospective cohort of Japanese men
    Norie Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Epidemiol Biomarkers Prev 17:930-7. 2008
    ..62 (1.15-2.29) and 1.53 (1.07-2.20), respectively. In conclusion, our results suggest that the intake of dairy products may be associated with an increased risk of prostate cancer...
  31. doi request reprint Alcohol consumption-associated breast cancer incidence and potential effect modifiers: the Japan Public Health Center-based Prospective Study
    Reiko Suzuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
    Int J Cancer 127:685-95. 2010
    ..15). Excessive alcohol intake was associated with an increase in the risk of breast cancer in this population. There was no statistical evidence for effect modification...
  32. doi request reprint Consumption of sodium and salted foods in relation to cancer and cardiovascular disease: the Japan Public Health Center-based Prospective Study
    Ribeka Takachi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Am J Clin Nutr 91:456-64. 2010
    ....
  33. doi request reprint Taste preferences and body weight change in Japanese adults: the JPHC Study
    Y Matsushita
    Department of Epidemiology and International Health, Research Institute, International Medical Center of Japan, Shinjuku ku, Tokyo, Japan
    Int J Obes (Lond) 33:1191-7. 2009
    ..Limited data are available with regard to longitudinal changes in body weight by food taste preference. Here, we examined the associations between taste preferences and weight change in adults for a large-scale cohort study in Japan...
  34. doi request reprint Plasma levels of C-reactive protein and serum amyloid A and gastric cancer in a nested case-control study: Japan Public Health Center-based prospective study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104 0045, Japan
    Carcinogenesis 31:712-8. 2010
    ..005). In conclusion, our results suggest that those who react strongly to inflammation or who have a high host immune response, as reflected by extremely elevated plasma levels of CRP and SAA, are at a high risk to develop gastric cancer...
  35. doi request reprint Plasma isoflavones and the risk of lung cancer in women: a nested case-control study in Japan
    Taichi Shimazu
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, 104 0045 Japan
    Cancer Epidemiol Biomarkers Prev 20:419-27. 2011
    ....
  36. doi request reprint Fruit and vegetable consumption and squamous cell carcinoma of the esophagus in Japan: the JPHC study
    Taiki Yamaji
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 123:1935-40. 2008
    ..Finally, cruciferous vegetables deserve further investigation as foods possibly effective in the prevention of esophageal SCC...
  37. doi request reprint Plasma testosterone and sex hormone-binding globulin concentrations and the risk of prostate cancer among Japanese men: a nested case-control study
    Norie Sawada
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Cancer Sci 101:2652-7. 2010
    ..In conclusion, in this nested case-control study, concentrations of circulating total testosterone, free testosterone or SHBG were not strongly associated with a risk for total prostate cancer...
  38. ncbi request reprint Plasma folate and risk of colorectal cancer in a nested case-control study: the Japan Public Health Center-based prospective study
    Tetsuya Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer Causes Control 19:67-74. 2008
    ..We investigated the association between plasma folate and the risk of colorectal cancer in a nested case-control study...
  39. doi request reprint Magnesium intake and type II diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study
    A Nanri
    Department of Epidemiology and International Health, International Clinical Research Center, National Center for Global Health and Medicine, Tokyo, Japan
    Eur J Clin Nutr 64:1244-7. 2010
    ..86 (0.63-1.16) and 0.92 (0.66-1.28) for men and women, respectively. Although a small effect cannot be excluded in men, magnesium intake may not be appreciably associated with risk of type II diabetes for Japanese adults...
  40. doi request reprint Overweight and obesity trends among Japanese adults: a 10-year follow-up of the JPHC Study
    Y Matsushita
    Department of Epidemiology and International Health, Research Institute, International Medical Center of Japan, Shinjuku ku, Tokyo, Japan
    Int J Obes (Lond) 32:1861-7. 2008
    ..Here, we describe changes in the prevalences of overweight and obesity and calculated the incidence of these indices during a 10-year follow-up period for a large-scale cohort study in Japan...
  41. doi request reprint Fish intake and type 2 diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study
    Akiko Nanri
    Department of Epidemiology and Prevention, International Clinical Research Center, National Center for Global Health and Medicine, Tokyo, Japan
    Am J Clin Nutr 94:884-91. 2011
    ..However, data from populations with high fish consumption are scarce...
  42. doi request reprint Intake of n-3 and n-6 polyunsaturated fatty acids and development of colorectal cancer by subsite: Japan Public Health Center-based prospective study
    Shizuka Sasazuki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    Int J Cancer 129:1718-29. 2011
    ..Our results suggest that intake of marine n-3 polyunsaturated fatty acids may be inversely related to the risk of cancer in the proximal site of the large bowel...
  43. doi request reprint Dietary calcium intake and risks of stroke, its subtypes, and coronary heart disease in Japanese: the JPHC Study Cohort I
    Mitsumasa Umesawa
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Stroke 39:2449-56. 2008
    ....
  44. pmc Education level and physical functional limitations among Japanese community residents-gender difference in prognosis from stroke
    Kaori Honjo
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan
    BMC Public Health 9:131. 2009
    ..We sought to examine the association between education level and physical functional limitations among Japanese men and women, and whether that association was modified by gender and history of stroke...
  45. doi request reprint Weight change and all-cause, cancer and cardiovascular disease mortality in Japanese men and women: the Japan Public Health Center-Based Prospective Study
    A Nanri
    Department of Epidemiology and International Health, Research Institute, International Medical Center of Japan, Shinjuku ku, Tokyo, Japan
    Int J Obes (Lond) 34:348-56. 2010
    ..It is unclear whether weight change during adulthood influences subsequent mortality in Asian populations, who have a relatively lean body mass...
  46. doi request reprint Plasma organochlorine levels and subsequent risk of breast cancer among Japanese women: a nested case-control study
    Motoki Iwasaki
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Sci Total Environ 402:176-83. 2008
    ..Our data do not support the hypothesis that plasma levels of p,p'-DDT, p,p'-DDE, HCB, and beta-HCH are associated with an overall increased risk of breast cancer among Japanese women...
  47. doi request reprint Dietary patterns and type 2 diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study
    A Nanri
    Department of Epidemiology and Prevention, National Center for Global Health and Medicine, Tokyo, Japan
    Eur J Clin Nutr 67:18-24. 2013
    ..We prospectively investigated the association between dietary patterns and risk of developing type 2 diabetes among Japanese adults...
  48. doi request reprint Relationship of smoking and smoking cessation with number of teeth present: JPHC Oral Health Study*
    T Yanagisawa
    Department of Oral Health Promotion, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Oral Dis 15:69-75. 2009
    ..Smoking is associated with the number of teeth. The purpose of this study was to determine the relationship of number of teeth with smoking and smoking cessation...
  49. doi request reprint Impact of whole body irradiation and vascular endothelial growth factor-A on increased beta cell mass after bone marrow transplantation in a mouse model of diabetes induced by streptozotocin
    S Nakayama
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, Tokyo, Japan
    Diabetologia 52:115-24. 2009
    ..However, the essential factors for the improvement of hyperglycaemia by bone marrow transplantation have not been fully elucidated. The aim of this study was to search for such factors...
  50. pmc Plasma vitamin D and risk of colorectal cancer: the Japan Public Health Center-Based Prospective Study
    T Otani
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Br J Cancer 97:446-51. 2007
    ..6; 95% confidence interval (CI), 1.0-20) and women (OR, 2.7, 95% CI, 0.94-7.6), compared with the combined category of the other quartiles. Our results suggest that a low level of plasma 25(OH)D may increase the risk of rectal cancer...
  51. pmc Association of body mass index and height with risk of prostate cancer among middle-aged Japanese men
    N Kurahashi
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Br J Cancer 94:740-2. 2006
    ....
  52. pmc Epidemiology of gastric cancer in Japan
    M Inoue
    Epidemiology and Prevention Division, Research Centre for Cancer Prevention and Screening, National Cancer Centre, 5 1 1 Tsukiji, Tokyo 104 0045, Japan
    Postgrad Med J 81:419-24. 2005
    ....
  53. pmc Impact of alcohol drinking on total cancer risk: data from a large-scale population-based cohort study in Japan
    M Inoue
    1Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Br J Cancer 92:182-7. 2005
    ..The simultaneous reduction of smoking is therefore important for reducing the effect of alcohol on cancer risk...
  54. doi request reprint Isoflavone intake and risk of lung cancer: a prospective cohort study in Japan
    Taichi Shimazu
    Research Center for Cancer Prevention and Screening, National Cancer Center Tokyo Japan
    Am J Clin Nutr 91:722-8. 2010
    ..Moreover, no prospective study has addressed this association in men...
  55. doi request reprint Dose-dense paclitaxel once a week in combination with carboplatin every 3 weeks for advanced ovarian cancer: a phase 3, open-label, randomised controlled trial
    Noriyuki Katsumata
    Department of Medical Oncology, National Cancer Center Hospital, Tokyo, Japan
    Lancet 374:1331-8. 2009
    ..Attempts to improve patient survival by including other drugs have yielded disappointing results. We compared a conventional regimen of paclitaxel and carboplatin with a dose-dense weekly regimen in women with advanced ovarian cancer...
  56. ncbi request reprint Risk factors of biliary tract cancer in a large-scale population-based cohort study in Japan (JPHC study); with special focus on cholelithiasis, body mass index, and their effect modification
    Seiji Ishiguro
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo, Japan
    Cancer Causes Control 19:33-41. 2008
    ..Particular focus was placed on a history of cholelithiasis, body mass index (BMI), and their effect modification, and whether risk differs by cancer subsite, namely by gallbladder cancer and extrahepatic bile duct cancer...
  57. ncbi request reprint Nitric oxide-independent effects of nitric oxide donors on energy metabolism in erythrocytes
    M Kashiba
    The National Institute of Health and Nutrition, Division of Geriatric Health and Nutrition, Tokyo, Japan
    Biochem Pharmacol 59:557-61. 2000
    ....
  58. doi request reprint Long-term results of gastrectomy for alpha-fetoprotein-producing gastric cancer
    M Inoue
    Gastric Surgery Division, National Cancer Centre Hospital, Tokyo, Japan
    Br J Surg 97:1056-61. 2010
    ..alpha-Fetoprotein (AFP)-producing gastric cancer is a rare tumour. It is said to have a high incidence of liver metastasis and poor prognosis. This study sought to evaluate long-term outcomes in such patients...
  59. pmc Impaired reductive regeneration of ascorbic acid in the Goto-Kakizaki diabetic rat
    M Kashiba
    The National Institute of Health and Nutrition, Division of Geriatric Health and Nutrition, 1 23 1 Toyama, Shinjuku, Tokyo, 162 8636, Japan
    Biochem J 351:313-8. 2000
    ..These results suggest that decreased AA-regenerating activity, probably through decreased expression of AKR, contributes to the decreased AA levels and increased oxidative stress in GK rats...
  60. ncbi request reprint Effect of FTY720 and ex vivo graft irradiation in rat small bowel transplantation: apoptosis of crypt cells and lymphocytes
    K Sugito
    Department of Pediatric Surgery, Nihon University, Tokyo, Japan
    Transplant Proc 39:3432-5. 2007
    ..We investigated the extent of apoptosis in crypt cells and Peyer's patches (PPs) during small bowel allograft rejection in rats to examine the effect of FTY720 and ex vivo graft irradiation during rejection...
  61. ncbi request reprint Impaired insulin secretion in vivo but enhanced insulin secretion from isolated islets in pancreatic beta cell-specific vascular endothelial growth factor-A knock-out mice
    N Iwashita
    Department of Medicine, Metabolism and Endocrinology, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo, 113 8421, Japan
    Diabetologia 50:380-9. 2007
    ..Endothelial cells are considered to be essential for normal pancreatic beta cell function. However, there have been no reports showing their importance for beta cell function...
  62. ncbi request reprint Growth and endocrine function during school age in very low-birth weight infants
    T Takeuchi
    Department of Pediatrics, School of Medicine, Showa University, Tokyo, Japan
    Pediatr Int 43:128-33. 2001
    ..Short stature and low bodyweight are commonly encountered problems in the clinical follow up of premature infants. However, details about the underlying pathophysiology are unknown in these cases...
  63. ncbi request reprint Efficacy of dentin adhesives in primary and permanent teeth
    T Asakawa
    Department of Pediatric Dentistry, Showa University School of Dentistry, Tokyo, Japan
    J Clin Pediatr Dent 25:231-6. 2001
    ..The detailed mechanism of dentin bonding was the same in both primary and permanent teeth...