Takashi Hojo

Summary

Affiliation: National Cancer Center
Country: Japan

Publications

  1. doi Use of the neo-adjuvant exemestane in post-menopausal estrogen receptor-positive breast cancer: a randomized phase II trial (PTEX46) to investigate the optimal duration of preoperative endocrine therapy
    Takashi Hojo
    Department of Breast Surgery, National Cancer Center Hospital, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo, Japan
    Breast 22:263-7. 2013
  2. doi Primary small cell carcinoma of the breast
    Takashi Hojo
    Breast Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Breast Cancer 16:68-71. 2009
  3. ncbi Evaluation of sentinel node biopsy by combined fluorescent and dye method and lymph flow for breast cancer
    Takashi Hojo
    National Cancer Center Hospital, Department of Surgery and Division of Breast Cancer, 5 1 1 Tsukiji Chuo ku, Tokyo, Japan
    Breast 19:210-3. 2010
  4. doi Comparison among different classification systems regarding the pathological response of preoperative chemotherapy in relation to the long-term outcome
    Tadahiko Shien
    Department of Breast Surgery, National Cancer Center Hospital, Tokyo, Japan
    Breast Cancer Res Treat 113:307-13. 2009
  5. ncbi Evaluation of axillary status in patients with breast cancer using thin-section CT
    Tadahiko Shien
    Division of Surgical Oncology, National Cancer Center Hospital, Tokyo, Japan
    Int J Clin Oncol 13:314-9. 2008
  6. doi Prognostic significance of mitotic figures in metastatic mammary ductal carcinoma to the lymph nodes
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, Chuo Ku, 104 0045, Tokyo, Japan
    Hum Pathol 42:1823-32. 2011
  7. doi Important histologic outcome predictors for patients with invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center Hospital, Tokyo, Japan
    Am J Surg Pathol 35:1484-97. 2011
  8. doi Atypical tumor-stromal fibroblasts in invasive ductal carcinomas of the breast treated with neoadjuvant therapy
    Takahiro Hasebe
    Clinical Trials and Practice Support Division, Pathology Consultation Service, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, 104 0045, Japan
    Hum Pathol 42:998-1006. 2011
  9. doi Histological factors for accurately predicting first locoregional recurrence of invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Diagnostic Pathology Section, Medical Support and Partnership Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
    Cancer Sci 104:1252-61. 2013
  10. doi 21-Gene expression profile assay on core needle biopsies predicts responses to neoadjuvant endocrine therapy in breast cancer patients
    Sadako Akashi-Tanaka
    Division of Breast Surgery, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo 104 0045, Japan
    Breast 18:171-4. 2009

Detail Information

Publications32

  1. doi Use of the neo-adjuvant exemestane in post-menopausal estrogen receptor-positive breast cancer: a randomized phase II trial (PTEX46) to investigate the optimal duration of preoperative endocrine therapy
    Takashi Hojo
    Department of Breast Surgery, National Cancer Center Hospital, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo, Japan
    Breast 22:263-7. 2013
    ..Therefore, we conducted the present study to investigate the potential benefits of neoadjuvant exemestane therapy with the goal of identifying the optimal treatment duration...
  2. doi Primary small cell carcinoma of the breast
    Takashi Hojo
    Breast Surgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Breast Cancer 16:68-71. 2009
    ..Therefore, the best therapy for primary small cell carcinoma of the breast may be surgery followed by adjuvant therapy similar to that recommended for small cell lung carcinoma...
  3. ncbi Evaluation of sentinel node biopsy by combined fluorescent and dye method and lymph flow for breast cancer
    Takashi Hojo
    National Cancer Center Hospital, Department of Surgery and Division of Breast Cancer, 5 1 1 Tsukiji Chuo ku, Tokyo, Japan
    Breast 19:210-3. 2010
    ..We compared the combination of radioisotope or dye with a fluorescence compound to analyze lymph flow to identify targets for SNB...
  4. doi Comparison among different classification systems regarding the pathological response of preoperative chemotherapy in relation to the long-term outcome
    Tadahiko Shien
    Department of Breast Surgery, National Cancer Center Hospital, Tokyo, Japan
    Breast Cancer Res Treat 113:307-13. 2009
    ..All three classifications analyzed were considered inadequate as the prognostic marker of the long-term outcome after NAC and further studies are warranted to optimize the prediction...
  5. ncbi Evaluation of axillary status in patients with breast cancer using thin-section CT
    Tadahiko Shien
    Division of Surgical Oncology, National Cancer Center Hospital, Tokyo, Japan
    Int J Clin Oncol 13:314-9. 2008
    ..We evaluated on the efficacy of preoperative axillary staging using contrast-enhanced computed tomography (CE-CT)...
  6. doi Prognostic significance of mitotic figures in metastatic mammary ductal carcinoma to the lymph nodes
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, Chuo Ku, 104 0045, Tokyo, Japan
    Hum Pathol 42:1823-32. 2011
    ..In conclusion, this study clearly confirmed the excellent outcome predictive power of the number of mitotic figures in metastatic mammary carcinoma to the lymph nodes...
  7. doi Important histologic outcome predictors for patients with invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center Hospital, Tokyo, Japan
    Am J Surg Pathol 35:1484-97. 2011
    ..These findings strongly suggest that these histologic factors are very useful for accurately predicting the outcomes of patients with invasive ductal carcinoma of the breast...
  8. doi Atypical tumor-stromal fibroblasts in invasive ductal carcinomas of the breast treated with neoadjuvant therapy
    Takahiro Hasebe
    Clinical Trials and Practice Support Division, Pathology Consultation Service, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, 104 0045, Japan
    Hum Pathol 42:998-1006. 2011
    ....
  9. doi Histological factors for accurately predicting first locoregional recurrence of invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Diagnostic Pathology Section, Medical Support and Partnership Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
    Cancer Sci 104:1252-61. 2013
    ....
  10. doi 21-Gene expression profile assay on core needle biopsies predicts responses to neoadjuvant endocrine therapy in breast cancer patients
    Sadako Akashi-Tanaka
    Division of Breast Surgery, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo 104 0045, Japan
    Breast 18:171-4. 2009
    ..84% and 73%, respectively). These results suggest that RS predicts responses to NAET with tamoxifen or anastrozole. Because this pilot study examined a small sample size, these results should be validated in larger studies...
  11. doi Grading system for lymph vessel tumor emboli: significant outcome predictor for patients with invasive ductal carcinoma of the breast who received neoadjuvant therapy
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
    Mod Pathol 23:581-92. 2010
    ....
  12. doi Clinicopathological features of tumors as predictors of the efficacy of primary neoadjuvant chemotherapy for operable breast cancer
    Tadahiko Shien
    Department of Surgery, National Cancer Center Hospital, Tokyo, Japan
    World J Surg 33:44-51. 2009
    ..Clinicopathological markers that predict patient response to NC are needed to individualize treatment...
  13. doi Atypical tumor-stromal fibroblasts in invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Clinical Trials and Practice Support Division, Pathology Consultation Service, Center for Cancer Control and Information Services, National Cancer Center Research Institute, Chuo Ku, Tokyo, Japan
    Am J Surg Pathol 35:325-36. 2011
    ....
  14. doi Prognostic factors in young Japanese women with breast cancer: prognostic value of age at diagnosis
    Miwa Yoshida
    Division of Breast Surgery, National Cancer Center Hospital, Tokyo, Japan
    Jpn J Clin Oncol 41:180-9. 2011
    ..The secondary objective was to assess prognostic factors specific for younger premenopausal patients...
  15. doi Usefulness of preoperative multidetector-row computed tomography in evaluating the extent of invasive lobular carcinoma in patients with or without neoadjuvant chemotherapy
    Tadahiko Shien
    Division of Breast Surgery, National Cancer Center Hospital, 1 1 5 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Breast Cancer 16:30-6. 2009
    ..The present study was conducted to assess the clinical usefulness of multidetector-row CT (MDCT) in determining the extent of invasive lobular carcinoma (ILC) and especially the extent of residual tumor after neoadjuvant chemotherapy (NAC)...
  16. doi The differences in the histological types of breast cancer and the response to neoadjuvant chemotherapy: the relationship between the outcome and the clinicopathological characteristics
    Tomoya Nagao
    Department of Breast Oncology, National Cancer Center Hospital, 5 1 1, Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Breast 21:289-95. 2012
    ..The response to NAC and the prognosis vary for each histological type. For some types, the prognosis was not related to the clinicopathological response to NAC...
  17. ncbi Primary tumor resection improves the survival of younger patients with metastatic breast cancer
    Tadahiko Shien
    Department of Breast Surgery, National Cancer Center Hospital, Okayama, Japan
    Oncol Rep 21:827-32. 2009
    ..Prospective studies are required to validate these findings and evaluate the impact of surgical intervention...
  18. doi Impact of recent parity on histopathological tumor features and breast cancer outcome in premenopausal Japanese women
    Akiko Kawano Nagatsuma
    Division of Breast and Medical Oncology, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Breast Cancer Res Treat 138:941-50. 2013
    ..07 (p = 0.011). Young breast cancer patients who had given birth more recently had tumors with more aggressive features and worse prognoses compared with patients who had given birth less recently or were nulliparous...
  19. ncbi Locoregional recurrence risk factors in breast cancer patients with positive axillary lymph nodes and the impact of postmastectomy radiotherapy
    Tomoya Nagao
    Department of Breast Oncology, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Int J Clin Oncol 18:54-61. 2013
    ..This study assessed the risk factors for LRR and the efficacy of PMRT in Japanese breast cancer patients with metastatic nodes...
  20. doi Prognostic factors for triple-negative breast cancer patients receiving preoperative systemic chemotherapy
    Sota Asaga
    Breast Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Clin Breast Cancer 13:40-6. 2013
    ..The aim of this study was to identify prognostic factors in triple-negative breast cancer patients receiving preoperative chemotherapy...
  21. doi Whole-breast volume perfusion images using 256-row multislice computed tomography: visualization of lesions with ductal spread
    Sadako Akashi-Tanaka
    Department of Breast Surgery, National Cancer Center Hospital, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo, 104 0045, Japan
    Breast Cancer 16:62-7. 2009
    ....
  22. doi Clinical efficacy of S-1 in pretreated metastatic breast cancer patients
    Tadahiko Shien
    Division of Surgical Oncology, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Jpn J Clin Oncol 38:172-5. 2008
    ..S-1, an oral fluoropyrimidine carbamate, is an active and well-tolerated agent against solid cancer. However, the clinical efficacy of S-1 in patients with metastatic breast cancer has not been determined...
  23. doi Feasibility of breast conserving surgery for Paget's disease
    Shunsuke Onoe
    Breast Cancer Group, Surgical Oncology Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Breast 20:515-8. 2011
    ..The standard treatment for Paget's disease of the breast is mastectomy. Since it is frequently associated with underlying carcinoma, many surgeons are reluctant to choose breast conserving surgery for Paget's disease...
  24. doi Synchronous unilateral triple breast cancers composed of invasive ductal carcinoma, invasive lobular carcinoma, and Paget's disease
    Shunsuke Onoe
    Pathology Section, Clinical Laboratory Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuoku, Tokyo, 104 0045, Japan
    Breast Cancer 21:241-5. 2014
    ..Cases of synchronous unilateral triple or more breast cancers were reviewed, and their histopathological characteristics, including the incidence of Paget's disease, is discussed...
  25. doi Sentinel lymph node biopsy using indigo carmine blue dye and the validity of '10% rule' and '4 nodes rule'
    Tomoya Nagao
    Department of Breast Oncology, National Cancer Center Hospital, 5 1 1, Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Breast 21:455-8. 2012
    ..From the results, removing the three most radioactive SLNs identified all cases of nodal metastasis without complications. These stopping rules were valid and useful under indigo carmine use too...
  26. doi Loss of heterozygosity on chromosome 16q suggests malignancy in core needle biopsy specimens of intraductal papillary breast lesions
    Miwa Yoshida
    Division of Diagnostic Pathology, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Virchows Arch 460:497-504. 2012
    ..007). Analysis of LOH on 16q may be helpful in making a definitive diagnosis in cases of papillary breast lesions, in both excised and CNB specimens...
  27. doi p53 expression in tumor-stromal fibroblasts forming and not forming fibrotic foci in invasive ductal carcinoma of the breast
    Takahiro Hasebe
    Pathology Consultation Service, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Service, National Cancer Center, Chuo Ku, Tokyo, Japan
    Mod Pathol 23:662-72. 2010
    ....
  28. ncbi Locoregional recurrence risk factors and the impact of postmastectomy radiotherapy on patients with tumors 5 cm or larger
    Tomoya Nagao
    Department of Breast Oncology, National Cancer Center Hospital, 5 1 1, Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Breast Cancer 21:292-301. 2014
    ..This study investigated what the risk factors are for LRR and the efficacy of PMRT in this patient population...
  29. ncbi Mucinous breast carcinoma with a lobular neoplasia component: A subset with aberrant expression of cell adhesion and polarity molecules and lack of neuroendocrine differentiation
    Kenjiro Jimbo
    Breast Surgery Division, National Cancer Center Hospital, Tokyo, Japan
    Pathol Int 64:217-23. 2014
    ..133). MUCs associated with LN components appear to be a biologically characteristic subset that frequently shows decreased cell-cell adhesion, cell polarity molecules and lack of neuroendocrine differentiation. ..
  30. doi Sentinel and nonsentinel lymph node assessment using a combination of one-step nucleic acid amplification and conventional histological examination
    Kenjiro Jimbo
    Breast Surgery Division, National Cancer Center Hospital, Tokyo, Japan Electronic address
    Breast 22:1194-9. 2013
    ..The aim of this study was to assess the usefulness of using a combination of OSNA and conventional histological examinations...
  31. doi Clinical and pathological features of intracystic papillary carcinoma of the breast
    Tomonori Akagi
    Division of Breast Surgery, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Surg Today 39:5-8. 2009
    ..To evaluate the clinicopathological features of intracystic papillary carcinoma (ICPC), which have not been established given its rarity and lack of standard diagnostic criteria...
  32. ncbi A case of primary gastric small cell carcinoma with a rare pattern of lymph node metastasis
    Hiroya Takeuchi
    Department of Surgery, National Tokyo Medical Center, 2 5 1 Higashigaoka, Tokyo, 152 8902, Japan
    Int J Gastrointest Cancer 36:99-104. 2005
    ..GSCC cells and adenocarcinoma cells independently metastasized to each regional lymph node. Further studies on the biological behavior of individual tumors may allow the development of new treatment strategies for GSCC...