Naoto Gotohda

Summary

Affiliation: National Cancer Center
Country: Japan

Publications

  1. ncbi request reprint Pancreatic resection for metastatic melanoma originating from the nasal cavity: a case report and literature review
    Motokazu Sugimoto
    National Cancer Center East, 6 5 1 Kashiwa no ha, Kashiwa, Chiba 277 8577, Japan
    Anticancer Res 33:567-73. 2013
  2. doi request reprint Surgical outcome of liver transection by the crush-clamping technique combined with Harmonic FOCUS™
    Naoto Gotohda
    Department of Surgical Oncology, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    World J Surg 36:2156-60. 2012
  3. ncbi request reprint The role of a protease inhibitor against hepatectomy
    Naoto Gotohda
    Department of Surgery, National Cancer Center Hospital East, Kashiwa, Japan
    Hepatogastroenterology 53:115-9. 2006
  4. ncbi request reprint Significant correlation between surgical stress of hepatectomy and changes in the serum levels of HGF, IL-6 and soluble Fas in patients with viral hepatitis
    Naoto Gotohda
    Department of Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha Kashiwa, 277 8577 Chiba, Japan
    Hepatogastroenterology 55:1400-3. 2008
  5. ncbi request reprint Deficient response of IL-6 impaired liver regeneration after hepatectomy in patients with viral hepatitis
    Naoto Gotohda
    Department of Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha Kashiwa, 277 8577 Chiba, Japan
    Hepatogastroenterology 55:1439-44. 2008
  6. ncbi request reprint Selection criteria for reduction hepatectomy in multiple advanced hepatocellular carcinoma
    Naoto Gotohda
    Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, Chiba, 277 8577, Japan
    Anticancer Res 26:4671-4. 2006
  7. ncbi request reprint New indication for reduction surgery in patients with advanced hepatocellular carcinoma with major vascular involvement
    Naoto Gotohda
    Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba, Japan
    World J Surg 30:431-8. 2006
  8. ncbi request reprint A case of anaplastic ductal carcinoma of the pancreas with production of granulocyte-colony stimulating factor
    Naoto Gotohda
    Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, Chiba, Japan
    Hepatogastroenterology 53:957-9. 2006
  9. ncbi request reprint The pattern of lymphatic metastases in superficial squamous cell carcinoma of the esophagus
    Naoto Gotohda
    Division of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Japan
    Hepatogastroenterology 52:105-7. 2005
  10. doi request reprint Predictors for early recurrence after hepatectomy for initially unresectable colorectal liver metastasis
    Shinichiro Takahashi
    Department of Hepato Biliary Pancreatic Surgery, National Cancer Center Hospital East, Chiba, Japan
    J Gastrointest Surg 17:939-48. 2013

Detail Information

Publications72

  1. ncbi request reprint Pancreatic resection for metastatic melanoma originating from the nasal cavity: a case report and literature review
    Motokazu Sugimoto
    National Cancer Center East, 6 5 1 Kashiwa no ha, Kashiwa, Chiba 277 8577, Japan
    Anticancer Res 33:567-73. 2013
    ..We review cases of malignant melanoma metastatic to the pancreas and further discuss their incidence, therapeutic strategy, and outcome of mucosal melanoma of the head and neck...
  2. doi request reprint Surgical outcome of liver transection by the crush-clamping technique combined with Harmonic FOCUS™
    Naoto Gotohda
    Department of Surgical Oncology, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    World J Surg 36:2156-60. 2012
    ..Hepatectomy can be performed by the clamp-crushing method using the HF instead of Kelly forceps. We obtained good results of liver resection with the HF, and report these outcomes in this study...
  3. ncbi request reprint The role of a protease inhibitor against hepatectomy
    Naoto Gotohda
    Department of Surgery, National Cancer Center Hospital East, Kashiwa, Japan
    Hepatogastroenterology 53:115-9. 2006
    ....
  4. ncbi request reprint Significant correlation between surgical stress of hepatectomy and changes in the serum levels of HGF, IL-6 and soluble Fas in patients with viral hepatitis
    Naoto Gotohda
    Department of Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha Kashiwa, 277 8577 Chiba, Japan
    Hepatogastroenterology 55:1400-3. 2008
    ..Liver damage after hepatectomy is still a serious concern. The present study was designed to clarify the relations between liver injury/surgical stress and cytokines after hepatectomy, in patients with viral hepatitis...
  5. ncbi request reprint Deficient response of IL-6 impaired liver regeneration after hepatectomy in patients with viral hepatitis
    Naoto Gotohda
    Department of Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha Kashiwa, 277 8577 Chiba, Japan
    Hepatogastroenterology 55:1439-44. 2008
    ..Liver regeneration after surgical resection is still a serious concern. The present study is designed to understand the relations between liver injury/regeneration and cytokines after hepatectomy with viral hepatitis...
  6. ncbi request reprint Selection criteria for reduction hepatectomy in multiple advanced hepatocellular carcinoma
    Naoto Gotohda
    Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, Chiba, 277 8577, Japan
    Anticancer Res 26:4671-4. 2006
    ..Few studies have compared the prognostic impact of reduction hepatectomy (RH) for advanced hepatocellular carcinoma (HCC) with that of non-surgical treatment or curative hepatectomy. Patients and..
  7. ncbi request reprint New indication for reduction surgery in patients with advanced hepatocellular carcinoma with major vascular involvement
    Naoto Gotohda
    Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba, Japan
    World J Surg 30:431-8. 2006
    ..The prognosis of advanced hepatocellular carcinoma (HCC) remains poor, particularly in patients with tumor thrombi (TT) in the major vessels...
  8. ncbi request reprint A case of anaplastic ductal carcinoma of the pancreas with production of granulocyte-colony stimulating factor
    Naoto Gotohda
    Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, Chiba, Japan
    Hepatogastroenterology 53:957-9. 2006
    ..Tumors with production of granulocyte-colony stimulating factor are highly malignant, and this patient died of hepatic failure four months after the operation...
  9. ncbi request reprint The pattern of lymphatic metastases in superficial squamous cell carcinoma of the esophagus
    Naoto Gotohda
    Division of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Japan
    Hepatogastroenterology 52:105-7. 2005
    ..We therefore analyzed patterns of lymph node metastasis in these patients...
  10. doi request reprint Predictors for early recurrence after hepatectomy for initially unresectable colorectal liver metastasis
    Shinichiro Takahashi
    Department of Hepato Biliary Pancreatic Surgery, National Cancer Center Hospital East, Chiba, Japan
    J Gastrointest Surg 17:939-48. 2013
    ..This retrospective study investigated the predictive factors for early recurrence after surgical resection for initially unresectable colorectal liver metastasis to elucidate indications for conversion strategies...
  11. doi request reprint Autoimmune pancreatitis with multifocal lesions
    Masatoshi Kajiwara
    Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    J Hepatobiliary Pancreat Surg 15:449-52. 2008
    ..Considering the favorable response of AIP to steroid therapy, it is clinically important to differentiate the focal type of AIP from pancreatic carcinoma and to know that AIP sometimes exhibits multiple lesions within the pancreas...
  12. ncbi request reprint Detail histologic analysis of nerve plexus invasion in invasive ductal carcinoma of the pancreas and its prognostic impact
    Shuichi Mitsunaga
    Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Japan
    Am J Surg Pathol 31:1636-44. 2007
    ....
  13. doi request reprint Clinicopathological features of stomach cancer with invasive micropapillary component
    Takeo Fujita
    Division of Digestive Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    Gastric Cancer 15:179-87. 2012
    ..However, few reports have described invasive micropapillary carcinoma in the gastrointestinal tract, particularly its involvement in gastric cancer...
  14. ncbi request reprint Surgical outcome of intraductal papillary mucinous neoplasms of the pancreas
    Toshio Nakagohri
    Department of Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, 277 8577, Japan
    Ann Surg Oncol 14:3174-80. 2007
    ..The objective of this study is to clarify the clinicopathologic features of intraductal papillary mucinous neoplasm of the pancreas and evaluate prognostic factors influencing survival...
  15. doi request reprint Evaluation of the prognostic factors and significance of lymph node status in invasive ductal carcinoma of the body or tail of the pancreas
    Takeo Fujita
    Division of Digestive Surgery, National Cancer Center Hospital East, Kashiwa, Japan
    Pancreas 39:e48-54. 2010
    ..We evaluated prognostic indicators for distal pancreatectomy with regional lymph node dissection in pancreatic body or tail carcinoma...
  16. ncbi request reprint Multiple resections for hepatic and pulmonary metastases of colorectal carcinoma
    Shinichiro Takahashi
    Department of Hepato biliary National Cancer Center Hospital East, Kashiwa, Chiba, Japan
    Jpn J Clin Oncol 37:186-92. 2007
    ....
  17. ncbi request reprint Nodal involvement is strongest predictor of poor survival in patients with invasive adenocarcinoma of the head of the pancreas
    Toshio Nakagohri
    Department of Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa 277 8577, Japan
    Hepatogastroenterology 53:447-51. 2006
    ..Pancreatic cancer is a devastating disease with an extremely poor prognosis. The outcome of pancreatic head cancer after surgical resection is still difficult to predict...
  18. ncbi request reprint Extrahepatic spread from hepatocellular carcinoma: who are candidates for aggressive anti-cancer treatment?
    Hiroshi Ishii
    Division of Hepatobilliary and Pancreatic Medical Oncology, National Cancer Center Hospital East, Kashiwa, Chiba 277 8577, Japan
    Jpn J Clin Oncol 34:733-9. 2004
    ..There is no standard treatment for patients with extrahepatic spread from hepatocellular carcinoma. The aim of this retrospective study was to identify candidates for aggressive intervention or new drug trial among such patients...
  19. doi request reprint Surgical procedure depending on the depth of tumor invasion in duodenal cancer
    Yuichiro Kato
    6 5 1 Kashiwanoha, Kashiwa, Chiba, 277 8577, Japan
    Jpn J Clin Oncol 44:224-31. 2014
    ..The aim of this study is to determine an appropriate operative method and an appropriate extent of lymph node dissection depending on tumor site or tumor invasion depth...
  20. doi request reprint Risk factor analysis and prevention of postoperative pancreatic fistula after distal pancreatectomy with stapler use
    Motokazu Sugimoto
    Department of Digestive Surgical Oncology, National Cancer Center Hospital East, 6 5 1 Kashiwa no ha, Kashiwa, Chiba 277 8577, Japan
    J Hepatobiliary Pancreat Sci 20:538-44. 2013
    ..Postoperative pancreatic fistula (POPF) is a major, intractable complication after distal pancreatectomy (DP). Risk factor evaluation and prevention of this complication are important tasks for pancreatic surgeons...
  21. doi request reprint Efficacy of the predicted operation time (POT) strategy for synchronous colorectal liver metastasis (SCLM): feasibility study for staged resection in patients with a long POT
    Kentaro Nakajima
    Department of Colorectal Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
    J Gastrointest Surg 17:688-95. 2013
    ..The aim of this study was to assess the efficacy of the predicted operation time (POT) strategy, which recommends staged resections in case of POT ≥6 h, otherwise selecting simultaneous resection...
  22. doi request reprint Laparoscopic proximal gastrectomy with jejunal interposition for gastric cancer in the proximal third of the stomach: a retrospective comparison with open surgery
    Takahiro Kinoshita
    Department of Surgical Oncology, National Cancer Center Hospital East, Chiba, Japan
    Surg Endosc 27:146-53. 2013
    ..In this study, we describe our technique for LPG with jejunal interposition (LPG-IP) and evaluate its safety and feasibility...
  23. doi request reprint Laparoscopic transhiatal resection for Siewert type II adenocarcinoma of the esophagogastric junction: operative technique and initial results
    Takahiro Kinoshita
    Department of Surgical Oncology, National Cancer Center Hospital East, Kashiwa, Japan
    Surg Laparosc Endosc Percutan Tech 22:e199-203. 2012
    ..The median length of the proximal margin was 14.5 mm. This operation is technically feasible and can be safely performed after adequate experience of LTG or LPG, though esophagojejunostomy in the mediastinum is technically demanding...
  24. doi request reprint Clinicopathological features and prognostic factors of adenocarcinoma of the esophagogastric junction according to Siewert classification: experiences at a single institution in Japan
    Yuichi Hosokawa
    Department of Surgical Oncology, National Cancer Center Hospital East, Kashiwa, Japan
    Ann Surg Oncol 19:677-83. 2012
    ..The aims of this study are to evaluate results of surgery for AEG, to clarify clinicopathological differences according to the Siewert classification, and to define prognostic factors...
  25. doi request reprint Relationship between the histological type of initial lesions and the risk for the development of remnant gastric cancers after gastrectomy for synchronous multiple gastric cancers
    Takeo Fujita
    Division of Digestive Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba, 277 8577, Japan
    World J Surg 34:296-302. 2010
    ..In this study we evaluated the potential risk factors attributable to the development of remnant gastric cancers after initial gastrectomy for multiple gastric cancers...
  26. ncbi request reprint Glypican-3 expression is correlated with poor prognosis in hepatocellular carcinoma
    Hirofumi Shirakawa
    Section for Cancer Immunotherapy, Investigative Treatment Division, National Cancer Center Hospital East, Chiba, Japan
    Cancer Sci 100:1403-7. 2009
    ..Multivariate analysis identified GPC3 expression (P = 0.034) as an independent prognostic factor for the overall survival. We showed that GPC3 expression is correlated with a poor prognosis in HCC patients...
  27. ncbi request reprint Postoperative serum alpha-fetoprotein level is a useful predictor of recurrence after hepatectomy for hepatocellular carcinoma
    Daisuke Nobuoka
    Section for Cancer Immunotherapy, Investigative Treatment Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba 277 8577, Japan
    Oncol Rep 24:521-8. 2010
    ..A positive level of AFP after operation might suggest a site of residual viable cancer. The need for effective adjuvant therapy and close follow-up is suggested in patients with a positive postoperative AFP level...
  28. doi request reprint Surgical outcome and prognostic factors in intrahepatic cholangiocarcinoma
    Toshio Nakagohri
    Department of Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, 277 8577, Japan
    World J Surg 32:2675-80. 2008
    ..The clinicopathologic features and surgical outcome of intrahepatic cholangiocarcinoma are not fully understood...
  29. doi request reprint Low serum level of cholinesterase at recurrence of pancreatic cancer is a poor prognostic factor and relates to systemic disorder and nerve plexus invasion
    Shuichi Mitsunaga
    Department of Upper Abdominal Surgery, National Cancer Center Hospital East, Kashiwa, Japan
    Pancreas 36:241-8. 2008
    ..This study aimed to find the associations between these sensitive markers and morphological factors of primary tumor that may indicate finding a way of pathogenesis of systemic disorder...
  30. ncbi request reprint Hepatectomy for hepatocellular carcinoma patients who meet the Milan criteria
    Hiroshi Ishii
    Division of Hepatobiliary and Pancreatic Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan
    Hepatogastroenterology 55:621-6. 2008
    ..Although hepatocellular carcinoma patients who meet the Milan criteria are optimal candidates for liver transplantation, most such patients in Japan have been treated without liver transplantation...
  31. doi request reprint Surgical treatment of lymph node metastases from hepatocellular carcinoma
    Shin Kobayashi
    National Cancer Center East Hospital, 6 5 1 Kashiwanoha, Kashiwa, Chiba, 277 8577, Japan
    J Hepatobiliary Pancreat Sci 18:559-66. 2011
    ..No consensus has been reached on the feasibility and efficacy of surgery for lymph node metastases (LNM) from hepatocellular carcinoma (HCC)...
  32. doi request reprint Schematic pancreatic configuration: a risk assessment for postoperative pancreatic fistula after pancreaticoduodenectomy
    Motokazu Sugimoto
    Department of Digestive Surgical Oncology, National Cancer Center Hospital East, 6 5 1, Kashiwa no ha, Kashiwa, Chiba Prefecture, 277 8577, Japan
    J Gastrointest Surg 17:1744-51. 2013
    ..The aim of this study was to assess simple and accurate risk factors for clinically relevant POPF based on a schematic understanding of the pancreatic configuration using preoperative multidetector computed tomography...
  33. doi request reprint Invasive micropapillary carcinoma of the ampulla of Vater with extensive lymph node metastasis: Report of a case
    Takeo Fujita
    Division of Digestive Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, 277 8577, Japan
    Surg Today 40:1197-200. 2010
    ..Tumor recurrence with progressive ascites and hydronephrosis was found 8 months after surgery, and the patient died of the disease 20 months after surgery...
  34. doi request reprint Predictive factors improving survival after gastrectomy in gastric cancer patients with peritoneal carcinomatosis
    Masayoshi Hioki
    Department of Digestive Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa City, Chiba 277 8577, Japan
    World J Surg 34:555-62. 2010
    ..The aim of this study was to review prognosis following gastrectomy for gastric cancer patients with synchronous peritoneal carcinomatosis and to identify predictive factors for improving survival after gastrectomy in this setting...
  35. doi request reprint Incidence, clinical presentation and pathological features of benign sclerosing cholangitis of unknown origin masquerading as biliary carcinoma
    Takeo Fujita
    Division of Digestive Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    J Hepatobiliary Pancreat Sci 17:139-46. 2010
    ..Some of these cases are pathologically classified as benign sclerosing cholangitis and are not clearly categorized. This study aims to elucidate the clinicopathological features of benign sclerosing cholangitis of unknown origin...
  36. doi request reprint Surgical outcomes of multicentric adenocarcinomas of the biliary tract
    Shin Kobayashi
    Department of Surgical Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
    Jpn J Clin Oncol 41:1079-85. 2011
    ..In comparison to single biliary cancers, distinct features of biliary multicentric adenocarcinomas are not yet clear...
  37. ncbi request reprint Treatment cost of pancreatic cancer in Japan: analysis of the difference after the introduction of gemcitabine
    Hiroshi Ishii
    Division of Hepatology and Pancreatic Medical Oncology, National Cancer Center Hospital East, Kashiwa, Chiba 277 8577, Japan
    Jpn J Clin Oncol 35:526-30. 2005
    ..Recent advances in cancer chemotherapy have increased not only the survival rate but also the treatment cost, although there has been little interest in cost analyses in Japan...
  38. ncbi request reprint Cystic endocrine tumor of the pancreas with an atypical multilocular appearance
    Masatoshi Kajiwara
    Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba, 277 8577, Japan
    J Hepatobiliary Pancreat Surg 14:586-9. 2007
    ..We finally made a diagnosis of pancreatic endocrine tumor (PET). As PET sometimes shows an atypical multicystic appearance, immunohistochemical staining is mandatory for its correct diagnosis...
  39. ncbi request reprint Primary tumor/vessel tumor/nodal tumor classification of extrahepatic bile duct carcinoma
    Takahiro Hasebe
    Surgical Pathology Section, Clinical Laboratory Division, National Cancer Center Hospital East, Kashiwa, Chiba, 277 0882, Japan
    Hum Pathol 39:37-48. 2008
    ..05). We conclude that the PVN classification is probably the most accurate prognostic classification system available for EBDC...
  40. doi request reprint Geminin expression in pancreatic neuroendocrine tumors: possible new marker of malignancy
    Masaki Aizawa
    Division of Digestive Surgery, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Japan
    Pancreas 41:512-7. 2012
    ..We evaluated geminin labeling index (LI) as a new prognostic indicator of pancreatic neuroendocrine tumor...
  41. doi request reprint Borderline resectable pancreatic cancer: rationale for multidisciplinary treatment
    Shinichiro Takahashi
    Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba, 277 8577, Japan
    J Hepatobiliary Pancreat Sci 18:567-74. 2011
    ..However, few reports are available on differences in tumor characteristics and prognoses among resectable pancreatic cancer (PC), BRPC, and unresectable PC...
  42. ncbi request reprint Glypican-3 is a useful diagnostic marker for a component of hepatocellular carcinoma in human liver cancer
    Hirofumi Shirakawa
    National Cancer Center Hospital East, Kashiwa, 277 8577 Chiba, Japan
    Int J Oncol 34:649-56. 2009
    ..The results of this study suggest that GPC3 is a biomarker that is sensitive and specific to HCC component of CHC, and CK7 and CK19 are markers for pathological cholangiocarcinoma component of CHC...
  43. pmc Predictive factors for anastomotic leakage after simultaneous resection of synchronous colorectal liver metastasis
    Kentaro Nakajima
    Department of Colorectal Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
    J Gastrointest Surg 16:821-7. 2012
    ....
  44. doi request reprint Compliance with and effects of preoperative immunonutrition in patients undergoing pancreaticoduodenectomy
    Hirofumi Shirakawa
    Hepatobiliary Pancreatic Surgery Division, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa 277 8577, Chiba, Japan
    J Hepatobiliary Pancreat Sci 19:249-58. 2012
    ..This study was conducted to ascertain the feasibility and effectiveness of preoperative enteral immunonutrition using an immune-enhanced formula (Impact) in patients undergoing pancreaticoduodenectomy...
  45. ncbi request reprint Incidence of the focal type of autoimmune pancreatitis in chronic pancreatitis suspected to be pancreatic carcinoma: experience of a single tertiary cancer center
    Masatoshi Kajiwara
    Department of Hepatobiliary Pancreatic Surgery, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
    Scand J Gastroenterol 43:110-6. 2008
    ..The aim of this study was to elucidate the incidence of focal-type AIP in resected chronic pancreatitis at a single tertiary cancer center. The clinical and radiological features of focal-type AIP were also evaluated...
  46. ncbi request reprint Short time to recurrence after hepatic resection correlates with poor prognosis in colorectal hepatic metastasis
    Shinichiro Takahashi
    Department of Surgery, National Cancer Center Hospital East, Kashiwa, Chiba 277 8577, Japan
    Jpn J Clin Oncol 36:368-75. 2006
    ..Early recurrence is a major problem after hepatic resection of colorectal hepatic metastasis (CHM). Our aim was to investigate the relationship between time to recurrence after CHM resection and overall survival...
  47. ncbi request reprint Positron emission tomography with F-18 fluorodeoxyglucose in evaluating colorectal hepatic metastasis down-staged by chemotherapy
    Shinichiro Takahashi
    Department of Hepato Biliary Pancreatic Surgery, National Cancer Center Hospital East, Chiba, Japan
    Anticancer Res 26:4705-11. 2006
    ..The efficacy of positron emission tomography with 18F fluoro-2-deoxy-D-glucose (FDG-PET) is obscure in evaluating viability or the extent of colorectal hepatic metastasis (CHM), down-staged by chemotherapy. Patients and..
  48. ncbi request reprint Prognostic impact of M2 macrophages at neural invasion in patients with invasive ductal carcinoma of the pancreas
    Motokazu Sugimoto
    Division of Pathology, Research Center for Innovative Oncology, National Cancer Center Hospital East, Japan Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital East, Japan Department of Surgery, Toho University School of Medicine, Japan
    Eur J Cancer 50:1900-8. 2014
    ..The aim of the present study was to investigate the prognostic impact of M2 macrophages at extrapancreatic nerve plexus invasion (plx-inv) of pancreatic IDC...
  49. doi request reprint Impact of tumor-associated macrophages on invasive ductal carcinoma of the pancreas head
    Kiyoshi Yoshikawa
    Pathology Division, Research Center for Innovative Oncology, Kashiwa, Japan
    Cancer Sci 103:2012-20. 2012
    ..High numbers of peripheral M2 macrophages were associated with large tumor size, early recurrence in the liver, local recurrence, and shortened survival time in patients with pancreatic IDC...
  50. doi request reprint Influence of excess body weight on the surgical outcomes of total gastrectomy
    Daisuke Nobuoka
    Department of Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba, 277 8577, Japan
    Surg Today 41:928-34. 2011
    ..We conducted this retrospective study to identify the influence of excess body weight on the surgical outcome of total gastrectomy (TG) and to evaluate recent advances in this operation...
  51. doi request reprint Inferior head resection of the pancreas for intraductal papillary mucinous neoplasms
    Toshio Nakagohri
    Department of Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, 277 8577, Japan
    J Hepatobiliary Pancreat Sci 17:798-802. 2010
    ..Thus, a variety of types of partial pancreatic resections have been advocated for treating these low-grade malignant tumors. However, the surgical outcome of IPMN after such limited pancreatectomy has not been fully clarified...
  52. ncbi request reprint Intraductal tubular carcinoma of the pancreas: case report with review of literature
    Masayoshi Hioki
    Division of Digestive Surgery, National Cancer Center Hospital East, Chiba, Japan
    Anticancer Res 30:4435-41. 2010
    ....
  53. doi request reprint Prevention of postoperative pancreatic fistula after total gastrectomy
    Daisuke Nobuoka
    Department of Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba, Japan
    World J Surg 32:2261-6. 2008
    ..Pancreatic fistula (PF) is still one of the serious complications after total gastrectomy (TG). The purpose of this study was to identify risk factors for PF after TG and to evaluate our attempts to prevent PF...
  54. doi request reprint Intraductal oncocytic papillary neoplasm of the extrahepatic bile duct: report of a case
    Yuichiro Kato
    Department of Digestive Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    Surg Today 42:1240-3. 2012
    ..Based on these findings, the tumor was diagnosed histologically as IOPN of the extrahepatic bile duct. The patient died of prostate cancer 51 months after surgery, but without evidence of recurrence of the IOPN...
  55. doi request reprint Dose-volume histogram analysis of the safety of proton beam therapy for unresectable hepatocellular carcinoma
    Mitsuhiko Kawashima
    Division of Particle Therapy and Radiation Oncology, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Japan
    Int J Radiat Oncol Biol Phys 79:1479-86. 2011
    ..To evaluate the safety and efficacy of radiotherapy using proton beam (PRT) for unresectable hepatocellular carcinoma...
  56. doi request reprint Phase I trial of a glypican-3-derived peptide vaccine for advanced hepatocellular carcinoma: immunologic evidence and potential for improving overall survival
    Yu Sawada
    Section for Cancer Immunotherapy, Investigative Treatment Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
    Clin Cancer Res 18:3686-96. 2012
    ..In this nonrandomized, open-label, phase I clinical trial, we analyzed the safety and efficacy of GPC3 peptide vaccination in patients with advanced HCC...
  57. ncbi request reprint [Surgical treatment for intrahepatic cholangiocarcinoma]
    Toshio Nakagohri
    Department of Surgical Oncology, National Cancer Center Hospital East
    Nihon Rinsho 64:469-75. 2006
  58. doi request reprint Predictive value of baseline neutrophil/lymphocyte ratio for T4 disease in wall-penetrating gastric cancer
    Masaki Aizawa
    Department of Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Japan
    World J Surg 35:2717-22. 2011
    ..We evaluated the predictive significance of the NLR and other serological parameters in patients with wall-penetrating gastric cancer...
  59. doi request reprint Surgical management for the reduction of postoperative hospital stay following distal pancreatectomy
    Kiyoshi Yoshikawa
    Department of Hepato Biliary and Pancreatic Surgery, National Cancer Center East Hospital, Chiba, Japan
    Hepatogastroenterology 58:1389-93. 2011
    ..None of the several surgical techniques and devices available for managing pancreatic remnant have been clinically evaluated...
  60. ncbi request reprint Pancreas-sparing duodenectomy for duodenal neoplasms including malignancies
    Masaru Konishi
    Department of Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa 277 8577, Japan
    Hepatogastroenterology 54:753-7. 2007
    ..Pancreas-sparing duodenectomy (PSD) represents an attractive operation for benign or premalignant duodenal disease. However, use of PSD is controversial for indications that include malignancy...
  61. ncbi request reprint Extrahepatic portal vein occlusion without recurrence after pancreaticoduodenectomy and intraoperative radiation therapy
    Shuichi Mitsunaga
    Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
    Int J Radiat Oncol Biol Phys 64:730-5. 2006
    ..In our institution, pancreaticoduodenectomy (PD) and IORT are often complicated by the development of extrahepatic portal vein occlusion (EHPO). The aim of this study was to characterize the phenomenon of EHPO after PD and IORT...
  62. ncbi request reprint Adenocarcinoma of the minor duodenal papilla with intraepithelial spread to the pancreatic duct
    Masatoshi Kajiwara
    Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    Virchows Arch 451:1075-81. 2007
    ....
  63. doi request reprint Surgical outcome of solid pseudopapillary tumor of the pancreas
    Toshio Nakagohri
    Department of Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, 277 8577, Japan
    J Hepatobiliary Pancreat Surg 15:318-21. 2008
    ..The best surgical treatment for solid pseudopapillary tumor of the pancreas is a matter of debate...
  64. doi request reprint Risk factors of surgical site infection after hepatectomy for liver cancers
    Shin Kobayashi
    National Cancer Center East Hospital, 6 5 1, Chiba, Kashiwanoha, Kashiwa, Chiba, 277 8577, Japan
    World J Surg 33:312-7. 2009
    ..Risk factors of surgical site infection (SSI) after hepatectomy under the guideline of Centers for Disease Control and Prevention (CDC) are not well examined...
  65. ncbi request reprint Volume reduction surgery for advanced hepatocellular carcinoma
    Kazuto Inoue
    Hepatobiliary Pancreatic Surgery Division, National Cancer Center Hospital East, 6 5 1 Kashiwanoha Kashiwa, 277 8577 Chiba, Japan
    J Cancer Res Clin Oncol 130:362-6. 2004
    ..The aim of this study was to evaluate the prognostic impact of reductive surgery on the survival of patients with advanced hepatocellular carcinoma (HCC)...
  66. ncbi request reprint Clinical and histopathological features of remnant gastric cancers, after gastrectomy for synchronous multiple gastric cancers
    Takeo Fujita
    Division of Digestive Surgery, National Cancer Center Hospital East, Kashiwa, Chiba 277 8577, Japan
    J Surg Oncol 100:466-71. 2009
    ..We evaluated the clinicopathological features of remnant gastric cancers, after initial gastrectomy for both single and multiple gastric cancers...
  67. doi request reprint Radiofrequency ablation for hepatocellular carcinoma induces glypican-3 peptide-specific cytotoxic T lymphocytes
    Daisuke Nobuoka
    Section for Cancer Immunotherapy, Investigative Treatment Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    Int J Oncol 40:63-70. 2012
    ..Combined treatment of RFA and immunotherapy is a reasonable strategy against HCC...
  68. doi request reprint Clinical and histopathological study of "follicular cholangitis": Sclerosing cholangitis with prominent lymphocytic infiltration masquerading as hilar cholangiocarcinoma
    Takeo Fujita
    Division of Digestive Surgery, National Cancer Center Hospital East Division of Clinical Pathology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
    Hepatol Res 40:1239-47. 2010
    ..Conclusion:  Benign sclerosing cholangitis has not been fully categorized, yet. Follicular cholangitis shows unique histopathological features and can be categorized as an independent entity...
  69. ncbi request reprint Solitary bile duct hamartoma of the liver
    Akihiro Kobayashi
    Surgery Division, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa City, Chiba 277 8577, Japan
    Scand J Gastroenterol 40:1378-81. 2005
    ..These findings lead us to conjecture that the lesion was a bile duct hamartoma, although its solitary nature and large size differed from those of typical bile duct hamartoma...
  70. doi request reprint Reactive lymphoid hyperplasia of the liver: literature review and 3 case reports
    Kiyoshi Yoshikawa
    Department of Hepato Biliary and Pancreatic Surgery, National Cancer Center Hospital East, Chiba, Japan
    Hepatogastroenterology 58:1349-53. 2011
    ..Because RLH occurs most commonly in middle-aged females, diagnosis of a hypervascular tumor of the liver requires particular care in these patients, especially if an extrahepatic malignancy is present...
  71. pmc Hepatocellular carcinoma with foamy histiocyte-like appearance: a deceptively clear cell carcinoma appearing variant
    Takuji Noro
    Department of Hepatobiliary Pancreatic Surgery, National Cancer Center Hospital East, Kashiwa, Japan
    Case Rep Gastroenterol 4:286-92. 2010
    ..To the best of our knowledge, this is the first report of this HCC variant...
  72. ncbi request reprint Importance of additional microvascular anastomosis in esophageal reconstruction after salvage esophagectomy
    Minoru Sakuraba
    Division of Head and Neck Surgery, National Cancer Center Hospital East, Kashiwa City, Chiba, Japan
    Plast Reconstr Surg 113:1934-9. 2004
    ..The authors believe that additional microvascular anastomosis helps prevent anastomotic leakage, especially in patients who have undergone salvage esophagectomy after curative chemoradiotherapy...