Feng Gao

Summary

Affiliation: National Institute of Advanced Industrial Science and Technology
Country: Japan

Publications

  1. ncbi request reprint Improvement of image quality in diffuse optical tomography by use of full time-resolved data
    Feng Gao
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Tsukuba, lbaraki, Japan
    Appl Opt 41:778-91. 2002
  2. ncbi request reprint Semi-three-dimensional algorithm for time-resolved diffuse optical tomography by use of the generalized pulse spectrum technique
    Feng Gao
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, 1 2 Namiki, Tsukuba, Ibaraki 305 8564, Japan
    Appl Opt 41:7346-58. 2002
  3. ncbi request reprint Optical tomographic mapping of cerebral haemodynamics by means of time-domain detection: methodology and phantom validation
    Feng Gao
    National Institute of Advanced Industrial Science and Technology, 1 2 Namiki, Tsukuba, Ibaraki, 305 8564, Japan
    Phys Med Biol 49:1055-78. 2004
  4. ncbi request reprint Imaging of in vitro chicken leg using time-resolved near-infrared optical tomography
    Huijuan Zhao
    National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Phys Med Biol 47:1979-93. 2002
  5. ncbi request reprint Maps of optical differential pathlength factor of human adult forehead, somatosensory motor and occipital regions at multi-wavelengths in NIR
    Huijuan Zhao
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    Phys Med Biol 47:2075-93. 2002
  6. ncbi request reprint Non-parametric estimation for baseline hazards function and covariate effects with time-dependent covariates
    Feng Gao
    Division of Biostatistics, Washington University School of Medicine, Campus Box 8067, 660 S Euclid Ave, St Louis, MO 63110, USA
    Stat Med 26:857-68. 2007
  7. ncbi request reprint Total light approach of time-domain fluorescence diffuse optical tomography
    Andhi Marjono
    Department of Mechanical Engineering and Intelligent Systems, University of Electro Communications, Chofu, Tokyo, Japan
    Opt Express 16:15268-85. 2008
  8. ncbi request reprint Time-resolved diffuse optical tomographic imaging for the provision of both anatomical and functional information about biological tissue
    Huijuan Zhao
    College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
    Appl Opt 44:1905-16. 2005
  9. doi request reprint Time-resolved diffuse optical tomography and its application to in vitro and in vivo imaging
    Huijuan Zhao
    Tianjin University, State Key Laboratory of Precision Measuring Technology and Instruments, Tianjin 3000072, China
    J Biomed Opt 12:062107. 2007
  10. ncbi request reprint Three-dimensional scheme for time-domain fluorescence molecular tomography based on Laplace transforms with noise-robust factors
    Limin Zhang
    College of Precision Instrument and Optoeletronics Engineering, Tianjin University, Tianjin 300072, China
    Opt Express 16:7214-23. 2008

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Improvement of image quality in diffuse optical tomography by use of full time-resolved data
    Feng Gao
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Tsukuba, lbaraki, Japan
    Appl Opt 41:778-91. 2002
    ....
  2. ncbi request reprint Semi-three-dimensional algorithm for time-resolved diffuse optical tomography by use of the generalized pulse spectrum technique
    Feng Gao
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, 1 2 Namiki, Tsukuba, Ibaraki 305 8564, Japan
    Appl Opt 41:7346-58. 2002
    ..We demonstrate our algorithm by comparing it with the calibrated 2-D reconstruction that is in widespread use as a shortcut to 3-D imaging and proving that the semi-3-D algorithm outperforms the calibrated 2-D algorithm...
  3. ncbi request reprint Optical tomographic mapping of cerebral haemodynamics by means of time-domain detection: methodology and phantom validation
    Feng Gao
    National Institute of Advanced Industrial Science and Technology, 1 2 Namiki, Tsukuba, Ibaraki, 305 8564, Japan
    Phys Med Biol 49:1055-78. 2004
    ..The methodology is also validated by experiments using a solid layered phantom...
  4. ncbi request reprint Imaging of in vitro chicken leg using time-resolved near-infrared optical tomography
    Huijuan Zhao
    National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
    Phys Med Biol 47:1979-93. 2002
    ....
  5. ncbi request reprint Maps of optical differential pathlength factor of human adult forehead, somatosensory motor and occipital regions at multi-wavelengths in NIR
    Huijuan Zhao
    Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
    Phys Med Biol 47:2075-93. 2002
    ..The DPF data will be useful for quantitative monitoring of the haemodynamic changes occurring in adult heads...
  6. ncbi request reprint Non-parametric estimation for baseline hazards function and covariate effects with time-dependent covariates
    Feng Gao
    Division of Biostatistics, Washington University School of Medicine, Campus Box 8067, 660 S Euclid Ave, St Louis, MO 63110, USA
    Stat Med 26:857-68. 2007
    ..Finally, the performance of the method is evaluated by several simulation studies...
  7. ncbi request reprint Total light approach of time-domain fluorescence diffuse optical tomography
    Andhi Marjono
    Department of Mechanical Engineering and Intelligent Systems, University of Electro Communications, Chofu, Tokyo, Japan
    Opt Express 16:15268-85. 2008
    ..The reconstructed images of fluorophore concentration show good quantitativeness and spatial reproducibility. By use of the total light approach, computation is performed much faster than the conventional ones...
  8. ncbi request reprint Time-resolved diffuse optical tomographic imaging for the provision of both anatomical and functional information about biological tissue
    Huijuan Zhao
    College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
    Appl Opt 44:1905-16. 2005
    ....
  9. doi request reprint Time-resolved diffuse optical tomography and its application to in vitro and in vivo imaging
    Huijuan Zhao
    Tianjin University, State Key Laboratory of Precision Measuring Technology and Instruments, Tianjin 3000072, China
    J Biomed Opt 12:062107. 2007
    ..Finally, in vitro and in vivo imaging examples are illustrated for validating the capibility of TR-DOT to provide not only the anatomical but also the physiological information of the objects...
  10. ncbi request reprint Three-dimensional scheme for time-domain fluorescence molecular tomography based on Laplace transforms with noise-robust factors
    Limin Zhang
    College of Precision Instrument and Optoeletronics Engineering, Tianjin University, Tianjin 300072, China
    Opt Express 16:7214-23. 2008
    ....
  11. ncbi request reprint Optimizing higher throughput methods to assess drug-drug interactions for CYP1A2, CYP2C9, CYP2C19, CYP2D6, rCYP2D6, and CYP3A4 in vitro using a single point IC(50)
    Feng Gao
    Pfizer Global Research and Development, Groton, CT, USA
    J Biomol Screen 7:373-82. 2002
    ..In addition, the algorithmic approach we propose would obviously be applicable for other in vitro bioactivity and therapeutic target enzyme and receptor screens...
  12. ncbi request reprint A self-normalized, full time-resolved method for fluorescence diffuse optical tomography
    Feng Gao
    College of Precision Instrument and Optoeletronics Engineering, Tianjin University, Tianjin 300072, China
    Opt Express 16:13104-21. 2008
    ....
  13. ncbi request reprint Combining sequence and time series expression data to learn transcriptional modules
    Anshul Kundaje
    Department of Computer Science, Columbia University, New York 10027, USA
    IEEE/ACM Trans Comput Biol Bioinform 2:194-202. 2005
    ....
  14. ncbi request reprint Impact of additive noise on system performance of a digital X-ray imaging system
    Da Zhang
    Center for Bioengineering, School of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, USA
    IEEE Trans Biomed Eng 54:69-73. 2007
    ..For example, at an exposure of 20 s, the DQE(O) is approximately 0.22, dropping to 0.11 at 3 lp/mm and to 0.022 at 8 lp/mm...
  15. ncbi request reprint A parametric comparison of diagnostic accuracy with three ordinal diagnostic groups
    Chengjie Xiong
    Division of Biostatistics, Washington University in St Louis, St Louis, MO 63110, USA
    Biom J 49:682-93. 2007
    ..Finally, we apply our proposed methodology to a real data set of 118 subjects to compare the diagnostic accuracy of early stage Alzheimer's disease (AD) from multiple neuropsychological tests...
  16. ncbi request reprint [Effects of insulin on cardiac function and coronary circulation in acute myocardial ischemia and reperfusion experiment with dogs]
    Heng Ma
    Department of Physiology, Fourth Military Medical University, Xi an 710032, China
    Zhonghua Yi Xue Za Zhi 86:3128-32. 2006
    ..To study the effect of insulin on cardiac functional recovery, coronary blood flow (CBF), coronary arterial function and coronary vascular endothelial cell apoptosis following acute myocardial ischemia/reperfusion (MI/R)...
  17. ncbi request reprint Reversal E/A value at end-inspiration might be more sensitive and accurate for diagnosing abnormal left ventricular diastolic function
    Lijun Yuan
    Department of Physiology, Tangdu Hospital, Fourth Militarry Medical University, Xi an, China
    Echocardiography 24:472-7. 2007
    ..It is well known that left ventricular (LV) filling decreases on inspiration and increases on expiration; however, respiratory effects on diastolic function have not been fully investigated...
  18. ncbi request reprint DoriC: a database of oriC regions in bacterial genomes
    Feng Gao
    Department of Physics, Tianjin University, Tianjin 300072, China
    Bioinformatics 23:1866-7. 2007
    ..AVAILABILITY: DoriC can be accessed from http://tubic.tju.edu.cn/doric/. SUPPLEMENTARY INFORMATION: Supplementary data are available at http://tubic.tju.edu.cn/doric/supplementary.htm...
  19. ncbi request reprint Contrast-enhanced first-pass myocardial perfusion magnetic resonance imaging with parallel acquisition at 3.0 Tesla
    Chun Ruan
    Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78284 6200, USA
    Invest Radiol 42:352-60. 2007
    ..This study tests the hypothesis that first-pass myocardial perfusion MRI using saturation recovery (SR)-TrueFISP with parallel imaging is superior to SR-TurboFLASH and a more achievable technique for clinical application at 3 T...
  20. doi request reprint The application of BTEM to UV-vis and UV-vis CD spectroscopies: the reaction of Rh4(CO)12 with chiral and achiral ligands
    Shuying Cheng
    Department of Chemical and Bimolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117576, Singapore
    Talanta 74:1132-40. 2008
    ..The present results indicate that UV-vis and UV-vis-CD spectroscopies can be successfully combined with an appropriate chemometric technique in order to monitor reactive organometallic systems having UV and Vis chromophores...
  21. ncbi request reprint Evaluation of on-line bradycardia boundary detectors from neonatal clinical data
    Francois Portet
    Department of Computing Science, University of Aberdeen, King s College, Aberdeen AB24 3UE, UK
    Conf Proc IEEE Eng Med Biol Soc 2007:3288-91. 2007
    ..5 to 8.7s vs. STD=35.3 to 19.9s). These methods will be integrated to the BabyTalk project which aims at summarizing neonatal clinical data as text in order to improve data management in Neonatal ICU...
  22. ncbi request reprint Indexing protein structures using suffix trees
    Feng Gao
    Department of Computer Science, Rensselaer Polytechnic Institute, Troy, NY, USA
    Methods Mol Biol 413:147-69. 2008
    ..49 out of 10 proteins from the same superfamily are obtained among the top 10 matches. These results outperform the best previous methods...
  23. ncbi request reprint Polymorphism in the human C-reactive protein (CRP) gene, serum concentrations of CRP, and the difference between intracranial and extracranial atherosclerosis
    Zhi zhong Liu
    The Center for Laboratory Diagnosis, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
    Clin Chim Acta 389:40-4. 2008
    ..We investigated the relationship of the distribution of cerebral atherosclerosis with triggered serum CRP concentrations following acute ischemic stroke/transient ischemic attack (IS/TIA) and CRP 1059G>C polymorphism...
  24. pmc Ori-Finder: a web-based system for finding oriCs in unannotated bacterial genomes
    Feng Gao
    Department of Physics, Tianjin University, Tianjin 300072, China
    BMC Bioinformatics 9:79. 2008
    ..Therefore, the increasing availability of genome sequences calls for improved software to identify oriCs in newly sequenced and unannotated bacterial genomes...
  25. doi request reprint Biomechanical functional and sensory modelling of the gastrointestinal tract
    Donghua Liao
    Mech Sense, Aalborg Hospital Science and Innovation Centre, Søndre Skovvej 15, 9000 Aalborg, Denmark
    Philos Transact A Math Phys Eng Sci 366:3281-99. 2008
    ..It will also improve the accuracy and efficiency of the medical procedures that could result in reduced cost for diagnosis and treatment...
  26. ncbi request reprint Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor
    David K Cole
    Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford University, Oxford, United Kingdom
    Proteins 67:65-74. 2007
    ..The analysis of this structure suggests that the higher affinity is achieved by providing a larger side chain that allows for an optimal contact to be made between the HLA alpha3 loop and the mutated CDR-like loops of CD8...
  27. pmc GC-Profile: a web-based tool for visualizing and analyzing the variation of GC content in genomic sequences
    Feng Gao
    Department of Physics, Tianjin University, Tianjin 300072, China
    Nucleic Acids Res 34:W686-91. 2006
    ..GC-Profile is freely available at the website http://tubic.tju.edu.cn/GC-Profile/. In addition, precompiled binaries, together with examples and documentation, can also be freely downloaded for a local execution...
  28. ncbi request reprint Determination of enantiomeric excess using the ultraviolet-circular dichroism and the high-performance liquid chromatography-circular dichroism methods
    Li Chen
    Chemical and Process Engineering Centre, 4 Engineering Drive 4, Block E5, Singapore 117576
    Appl Spectrosc 57:797-804. 2003
    ..Compared with the UV-CD method, the results show that excellent results are more readily obtained using the HPLC-CD method. With the systems studied, the latter usually provided outstanding estimations of e.e with low error percentages...
  29. ncbi request reprint Comparison of various algorithms for recognizing short coding sequences of human genes
    Feng Gao
    Department of Physics, Tianjin University, Tianjin 300072, China
    Bioinformatics 20:673-81. 2004
    ..The paper is devoted to assessing various algorithms, including those currently available and the new ones proposed here, in order to find the best algorithm to solve the issue...
  30. ncbi request reprint Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics
    Franco Lombardo
    Molecular Properties Group, Pfizer Global Research and Development, Groton Laboratories, Groton, Connecticut 06340, USA
    J Med Chem 47:1242-50. 2004
    ..The reduction in the use of animals and the overall faster and cheaper accessibility of the parameters used make this method highly attractive for prospectively predicting the VD of new chemical entities in humans...
  31. pmc Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
    Feng Gao
    Department of Biological Sciences, Columbia University, New York, New York 10027, USA
    BMC Bioinformatics 5:31. 2004
    ..The challenge is to extract useful information about the global regulatory network from these data...
  32. ncbi request reprint Simple strategies for reducing sample loads in in vitro metabolic stability high-throughput screening experiments: a comparison between traditional, two-time-point and pooled sample analyses
    Sabrina X Zhao
    Candidate Enhancement Group, Exploratory Medicinal Sciences, Pfizer Inc, Eastern Point Road MS 8118W 102, Groton, Connecticut 06340, USA
    J Pharm Sci 94:38-45. 2005
    ..98 and 0.97, respectively. Both methods have the potential to: 1. produce data of similar quality to traditional high throughput ADME assays, 2. be easily implemented, 3. shorten analytical run times, and 4. be reproducible and robust...
  33. ncbi request reprint MSurvPow: a FORTRAN program to calculate the sample size and power for cluster-randomized clinical trials with survival outcomes
    Feng Gao
    Division of Biostatistics, Washington University School of Medicine, St Louis, MO 63110, USA
    Comput Methods Programs Biomed 78:61-7. 2005
    ..In this paper, a user-friendly FORTRAN 90 program was provided to implement this method and a simple example was used to illustrate the features of the program...
  34. ncbi request reprint Coronavirus phylogeny based on a geometric approach
    Wen Xin Zheng
    Department of Physics, Tianjin University, Tianjin 300072, China
    Mol Phylogenet Evol 36:224-32. 2005
    ..Because the phylogenetic relationships are inferred from the whole genome, instead of some individual genes, the present method represents a new direction of phylogeny study in the post-genome era...
  35. ncbi request reprint Phosphodiesterase 5 inhibitor, zaprinast, selectively increases cerebral blood flow in the ischemic penumbra in the rat brain
    Feng Gao
    Department of Neurosurgery, University of Yamanashi, Faculty of Medicine, Yamanashi 409 3898, Japan
    Neurol Res 27:638-43. 2005
    ..cGMP-specific phosphodiesterase type 5 (PDE5) inhibitor increases intracellular cGMP levels. This study investigated the effect of the PDE5 inhibitor on the ischemic brain...
  36. ncbi request reprint Segmentation algorithm for DNA sequences
    Chun Ting Zhang
    Department of Physics, Tianjin University, Tianjin 300072, China
    Phys Rev E Stat Nonlin Soft Matter Phys 72:041917. 2005
    ..Particularly, it is much simpler and faster than the entropy-based method. Therefore, the new algorithm is more suitable for analyzing long genome sequences, such as human and other newly sequenced eukaryotic genome sequences...
  37. ncbi request reprint A hybrid mixture discriminant analysis-random forest computational model for the prediction of volume of distribution of drugs in human
    Franco Lombardo
    Computational Chemistry and Scientific Computing Groups and Groton Non Clinical Statistics, Pfizer Global Research and Development, Groton Laboratories, Groton, Connecticut 06340, USA
    J Med Chem 49:2262-7. 2006
    ..The computational model described can predict human VD(ss) with an accuracy comparable to predictions requiring substantially greater effort and can be applied in place of animal experimentation...
  38. ncbi request reprint Isochore structures in the chicken genome
    Feng Gao
    Department of Physics, Tianjin University, China
    FEBS J 273:1637-48. 2006
    ..The cumulative GC profile, equipped with the new segmentation algorithm, would be an appropriate starting point for analyzing the isochore structures of higher eukaryotic genomes...
  39. ncbi request reprint Retrospective motion correction protocol for high-resolution anatomical MRI
    Peter Kochunov
    Research Imaging Center, University of Texas Health Science Center at San Antonio, Texas, USA
    Hum Brain Mapp 27:957-62. 2006
    ..RMC was tested on 35 subjects who were considered at high risk for head motion. Our results show that RMC provided better contrast-to-noise ratio and boundary detail when compared to nonmotion-corrected averaged images...
  40. pmc Stress analysis in a layered aortic arch model under pulsatile blood flow
    Feng Gao
    Graduate School of Information Science, Japan Advanced Institute of Science and Technology, 1 1 Asahidai, Nomi, Ishikawa, 923 1292, Japan
    Biomed Eng Online 5:25. 2006
    ..The present study is concerned with the stress distribution in a layered aortic arch model with interaction between pulsatile flow and the wall of the blood vessel...
  41. ncbi request reprint Controlled bimolecular collisions allow sub-diffraction limited microscopy of lipid vesicles
    Erwen Mei
    Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Phys Chem Chem Phys 8:2077-82. 2006
    ..The principle of this method of trajectory time distribution optical microscopy (TTDOM) could be used in a far field optical microscopic system with a resolution of several nanometers...
  42. ncbi request reprint Computational method for muscle-path representation in musculoskeletal models
    Feng Gao
    Institute of Mechanical Engineering, Aalborg University, Pontoppidanstraede 101, 9220 Aalborg East, Denmark
    Biol Cybern 87:199-210. 2002
    ..Any level of geometric accuracy can be obtained by increasing the number of cross sections and the number of line segments in each cross section. The algorithm is computationally efficient even for large numbers of cross sections...