K Nasu

Summary

Country: Japan

Publications

  1. ncbi request reprint Atypical polypoid adenomyoma in a patient with hyperprolactinemia
    K Nasu
    Department of Obstetrics and Gynecology, Oita Medical University, Oita, Japan
    Int J Gynecol Cancer 11:326-8. 2001
  2. ncbi request reprint Expression of polo-like kinase in ovarian cancer is associated with histological grade and clinical stage
    N Takai
    Department of Obstetrics and Gynecology, Oita Medical University, Oita 879 5593, Japan
    Cancer Lett 164:41-9. 2001
  3. ncbi request reprint Effects of interleukin-4 on the in-vitro production of cytokines by human endometrial stromal cells
    K Nasu
    Department of Obstetrics and Gynecology, Oita Medical University, Hasama machi, Oita 879 5593, Japan
    Mol Hum Reprod 7:265-70. 2001
  4. ncbi request reprint Id1 expression is associated with histological grade and invasive behavior in endometrial carcinoma
    N Takai
    Department of Obstetrics and Gynecology, Oita Medical University, 879 5593, Oita, Japan
    Cancer Lett 165:185-93. 2001
  5. ncbi request reprint Expression of c-Ets1 is associated with malignant potential in endometrial carcinoma
    N Takai
    Department of Obstetrics and Gynecology, Oita Medical University, Oita, Japan
    Cancer 89:2059-67. 2000
  6. ncbi request reprint Polo-like kinase (PLK) expression in endometrial carcinoma
    N Takai
    Department of Obstetrics and Gynecology, Oita Medical University, Oita, 879 5593, Japan
    Cancer Lett 169:41-9. 2001
  7. ncbi request reprint Expression of hepatocyte growth factor in cultured human endometrial stromal cells is induced through a protein kinase C-dependent pathway
    K Nasu
    Department of Obstetrics and Gynecology, Oita Medical University, Hasama machi, Oita 879 5593, Japan
    Biol Reprod 60:1183-7. 1999
  8. ncbi request reprint Expression of epithelial neutrophil-activating peptide 78 in cultured human endometrial stromal cells
    K Nasu
    Department of Obstetrics and Gynecology, Oita Medical University, Hasama machi, Oita 879 5593, Japan
    Mol Hum Reprod 7:453-8. 2001
  9. ncbi request reprint Expression of receptor tyrosine kinase EphB4 and its ligand ephrin-B2 is associated with malignant potential in endometrial cancer
    N Takai
    Department of Obstetrics and Gynecology, Oita Medical University, Hasama machi, Oita 879 5593, Japan
    Oncol Rep 8:567-73. 2001
  10. ncbi request reprint Platelet-activating factor induces an imbalance between matrix metalloproteinase-1 and tissue inhibitor of metalloproteinases-1 expression in human uterine cervical fibroblasts
    T Sugano
    Department of Obstetrics and Gynecology, Oita Medical University, Oita 879 5593, Japan
    Biol Reprod 62:540-6. 2000

Detail Information

Publications26

  1. ncbi request reprint Atypical polypoid adenomyoma in a patient with hyperprolactinemia
    K Nasu
    Department of Obstetrics and Gynecology, Oita Medical University, Oita, Japan
    Int J Gynecol Cancer 11:326-8. 2001
    ..It is suggested that ovarian dysfunction caused by hyperprolactinemia may be involved in the pathogenesis of atypical polypoid adenomyoma in the present case...
  2. ncbi request reprint Expression of polo-like kinase in ovarian cancer is associated with histological grade and clinical stage
    N Takai
    Department of Obstetrics and Gynecology, Oita Medical University, Oita 879 5593, Japan
    Cancer Lett 164:41-9. 2001
    ..Thus, in addition to being of diagnostic value, PLK activity in ovarian tumors may be modulated by chemotherapeutic agents or gene therapy to therapeutic effect...
  3. ncbi request reprint Effects of interleukin-4 on the in-vitro production of cytokines by human endometrial stromal cells
    K Nasu
    Department of Obstetrics and Gynecology, Oita Medical University, Hasama machi, Oita 879 5593, Japan
    Mol Hum Reprod 7:265-70. 2001
    ..The increased concentration of these cytokines in the local environment may contribute to the maintenance of early pregnancy by modulating the immune reaction at the feto-maternal interface...
  4. ncbi request reprint Id1 expression is associated with histological grade and invasive behavior in endometrial carcinoma
    N Takai
    Department of Obstetrics and Gynecology, Oita Medical University, 879 5593, Oita, Japan
    Cancer Lett 165:185-93. 2001
    ..05) and the presence of invasion to >1/2 myometrium (P<0.05). Our results demonstrate that increased Id1 expression in endometrial carcinoma correlates with the malignant potential of this tumor...
  5. ncbi request reprint Expression of c-Ets1 is associated with malignant potential in endometrial carcinoma
    N Takai
    Department of Obstetrics and Gynecology, Oita Medical University, Oita, Japan
    Cancer 89:2059-67. 2000
    ..It might play a role in the regulation of physiologic processes such as cell proliferation and differentiation and also is associated with angiogenesis, cell migration, and tumor invasion...
  6. ncbi request reprint Polo-like kinase (PLK) expression in endometrial carcinoma
    N Takai
    Department of Obstetrics and Gynecology, Oita Medical University, Oita, 879 5593, Japan
    Cancer Lett 169:41-9. 2001
    ..Thus, in addition to being of diagnostic value, modulation of PLK activity in the tumors by chemotherapeutic agents or gene therapy may prove to be of therapeutic value...
  7. ncbi request reprint Expression of hepatocyte growth factor in cultured human endometrial stromal cells is induced through a protein kinase C-dependent pathway
    K Nasu
    Department of Obstetrics and Gynecology, Oita Medical University, Hasama machi, Oita 879 5593, Japan
    Biol Reprod 60:1183-7. 1999
    ..HGF secreted by ESC may be involved in the regeneration of the endometrium during the normal menstrual cycle...
  8. ncbi request reprint Expression of epithelial neutrophil-activating peptide 78 in cultured human endometrial stromal cells
    K Nasu
    Department of Obstetrics and Gynecology, Oita Medical University, Hasama machi, Oita 879 5593, Japan
    Mol Hum Reprod 7:453-8. 2001
    ..The modulation of ENA-78 concentration in the local environment by these mediators may contribute to the normal and pathological processes of human reproduction through regulation of leukocyte trafficking into the endometrium...
  9. ncbi request reprint Expression of receptor tyrosine kinase EphB4 and its ligand ephrin-B2 is associated with malignant potential in endometrial cancer
    N Takai
    Department of Obstetrics and Gynecology, Oita Medical University, Hasama machi, Oita 879 5593, Japan
    Oncol Rep 8:567-73. 2001
    ....
  10. ncbi request reprint Platelet-activating factor induces an imbalance between matrix metalloproteinase-1 and tissue inhibitor of metalloproteinases-1 expression in human uterine cervical fibroblasts
    T Sugano
    Department of Obstetrics and Gynecology, Oita Medical University, Oita 879 5593, Japan
    Biol Reprod 62:540-6. 2000
    ..Results suggest that PAF may accelerate collagenolysis in the human uterine cervix by inducing an imbalance in the activity between MMP-1 and TIMP-1, thus contributing to the cervical ripening during parturition...
  11. ncbi request reprint Primary mucinous adenocarcinoma of the vagina
    K Nasu
    Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Oita, Japan
    Eur J Gynaecol Oncol 31:679-81. 2010
    ..We report a case of advanced stage primary mucinous adenocarcinoma of the vagina that showed a highly aggressive course and resistance to combination chemotherapy with paclitaxel and carboplatin...
  12. ncbi request reprint Effects of platelet-activating factor on cytokine production by human uterine cervical fibroblasts
    T Sugano
    Department of Obstetrics and Gynecology, Oita Medical University, 1 1 Idaigaoka, Hasama, Oita 879 5593, Japan
    Mol Hum Reprod 7:475-81. 2001
    ..PAF may stimulate local production of cytokines which may induce migration of leukocytes and accelerate collagenolysis in the uterine cervix, thus contributing to cervical ripening during parturition...
  13. ncbi request reprint Involvement of resistance to apoptosis in the pathogenesis of endometriosis
    K Nasu
    Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Oita, Japan
    Histol Histopathol 24:1181-92. 2009
    ..The role of apoptosis in the pathogenesis of endometriosis and the basic and clinical research on the current medical treatment for endometriosis from the view of apoptosis will be discussed...
  14. ncbi request reprint Malignant lymphoma of the vagina successfully treated with rituximab, adryamicin, cyclophosphamide, vincristine sulfate, and prednisolone
    K Nasu
    Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Oita, Japan
    Eur J Gynaecol Oncol 33:219-22. 2012
    ..We report a case of vaginal DLBCL successfully treated with chemotherapy consisting of rituximab, adryamicin, cyclophosphamide, vincristine sulfate, and prednisolone (R-CHOP), followed by pelvic irradiation...
  15. ncbi request reprint Torsion of a functional ovarian cyst in a premenopausal patient receiving tamoxifen
    K Nasu
    Department of Obstetrics and Gynecology, Oita Medical University, Hasama machi, Oita, Japan
    Gynecol Obstet Invest 48:200-2. 1999
    ..This ovarian cyst was believed to have developed during tamoxifen administration...
  16. ncbi request reprint Endometrioid adenocarcinoma arising from adenomyosis
    N Takai
    Department of Obstetrics and Gynecology, Oita Medical University, Hasama machi, Oita, Japan
    Gynecol Obstet Invest 48:141-4. 1999
    ..We present 2 rare cases of adenocarcinoma arising from adenomyosis. The relationship between prior frequent estrogen use and carcinogenesis and the possible effects of chemotherapy and radiation therapy are reviewed...
  17. ncbi request reprint Complete response to radiation therapy in a patient with chemotherapy-resistant ovarian clear cell adenocarcinoma
    N Takai
    Department of Obstetrics and Gynecology, Oita Medical University, Hasama machi, Oita, 879 5593, Japan
    Arch Gynecol Obstet 267:98-100. 2002
    ..In an effort to maximize salvage potential and quality of life while minimizing toxicity, selected patients with ovarian cancer should be treated with radiation therapy directed to residual or recurrent sites...
  18. ncbi request reprint Bowel obstruction due to endometriosis in the rectovaginal septum
    N Takai
    Department of Obstetrics and Gynecology, Oita University Faculty of Medicine, Oita, Japan
    Clin Exp Obstet Gynecol 35:295-6. 2008
    ..Preoperative and postoperative gonadotropin-releasing hormone analog and aromatase inhibitor therapy promote relief of clinical symptoms, a reduction of tumor volume and a better approach to radical surgery...
  19. ncbi request reprint Beta-hydroxyisovalerylshikonin induces apoptosis and G0/G1 cell-cycle arrest of endometriotic stromal cells: a preliminary in vitro study
    M Nishida
    Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Oita, Japan
    Hum Reprod 21:2850-6. 2006
    ..The aim of this study is to evaluate the effects of beta-HIVS on the proliferation, cell cycle and apoptosis of endometriotic stromal cells...
  20. ncbi request reprint Expression of cathepsin L in normal endometrium and endometrial cancer
    K Nasu
    Department of Obstetrics and Gynecology, Oita Medical University, Hasama machi, Oita 879 5593, Japan
    Eur J Obstet Gynecol Reprod Biol 99:102-5. 2001
    ..To evaluate the expression of cathepsin L in normal endometrium and endometrial adenocarcinoma...
  21. ncbi request reprint Human oviductal epithelial cells express Toll-like receptor 3 and respond to double-stranded RNA: Fallopian tube-specific mucosal immunity against viral infection
    K Nasu
    Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Oita, Japan
    Hum Reprod 22:356-61. 2007
    ..The aim of this study was to evaluate the site-specific immunoregulatory mechanisms against viral infection in human Fallopian tubes...
  22. ncbi request reprint Depression and pregnancy-associated death by suicide after spinal cord injury: a case report
    K Kai
    Department of Obstetrics and Gynecology, Kenwakai Otemachi Hospital, Fukuoka, Japan
    Clin Exp Obstet Gynecol 39:532-4. 2012
    ..To report a case of a pregnant woman with traumatic spinal cord injury complicated with a psychiatric disorder...
  23. ncbi request reprint Management of patients with carcinoma of the cervix with anuric renal failure
    N Takai
    Department of Obstetrics and Gynecology, Oita University Faculty of Medicine, Hasama machi, Oita 879 5593, Japan
    Int J Gynaecol Obstet 88:156-7. 2005
  24. ncbi request reprint Gastrointestinal stromal tumor arising in the rectovaginal septum
    K Nasu
    Department of Obstetrics and Gynecology, Oita National Hospital, Oita Medical University, Hasama machi, Oita 879 5593, Japan
    Int J Gynecol Cancer 14:373-7. 2004
    ..The patient is now healthy without evidence of recurrence at 13 months after surgery. Gynecologists should be aware of rectal GIST arising in the rectovaginal space as a differential diagnosis of vaginal submucosal tumor...
  25. ncbi request reprint c-Ets1 is a promising marker in epithelial ovarian cancer
    N Takai
    Department of Obstetrics and Gynecology, Oita Medical University, Oita 879 5593, Japan
    Int J Mol Med 9:287-92. 2002
    ..05). Our results demonstrate that c-Ets1 expression in epithelial ovarian cancer correlates to the malignant potential of the tumor...
  26. ncbi request reprint The effect of epidermal growth factor on vascular endothelial growth factor secretion by endometrial stromal cells
    Y Kawano
    Department of Obstetrics and Gynecology, Oita Medical University, Hasama machi, Japan
    Clin Exp Med 2:69-75. 2002
    ..VEGF is believed to be induced by EGF through mechanisms involving tyrosine kinase and phosphatidylinositol 3-kinase. The increase in VEGF may contribute to neovascularization that promotes proliferation of endometrium and placentation...