Affiliation: Nara Women's University
- Inhibition of eosinophilia in vivo by a small molecule inhibitor of very late antigen (VLA)-4Hiromi Okigami
Bayer Yakuhin, Ltd, Research Center Kyoto, Respiratory Disease Research, Japan
Eur J Pharmacol 559:202-9. 2007..These data support the use of small molecule VLA-4 antagonists in the treatment of relevant diseases, such as asthma, atopic dermatitis, or allergic rhinitis...
- Discovery and evaluation of terephthalic acid derivatives as potent alpha4beta1 integrin antagonistsGerhard Muller
Bayer AG, Central Research, Building Q18, D 51368 Leverkusen, Germany
J Enzyme Inhib Med Chem 18:309-12. 2003..The compounds 2, 10-12, 14, and 16-17 inhibited the adhesion in a cell based assay in the low and sub micromolar range...