Research Topics
Species | Hajime OginoSummaryAffiliation: Nara Institute of Science and Technology Country: Japan Publications
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Detail Information
Publications
Comparative genomics-based identification and analysis of cis-regulatory elementsHajime Ogino
Graduate School of Biological Sciences, Nara Institute of Science and Technology NAIST, Ikoma, Nara, Japan
Methods Mol Biol 917:245-63. 2012..The co-transgenesis assay, which directly uses polymerase chain reaction products, quickly screens for the activity of the candidate elements in a cloning-free manner...
Transcription factors involved in lens development from the preplacodal ectodermHajime Ogino
Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5, Takayama, Ikoma, Nara, 630 0192, Japan
Dev Biol 363:333-47. 2012..This overview also sheds light upon the mechanisms of how preplacodal gene activities lead to the activation of genes involved in lens-specification...
Resources and transgenesis techniques for functional genomics in XenopusHajime Ogino
Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara, Japan
Dev Growth Differ 51:387-401. 2009..Effective use of these resources and techniques will help to reveal the overall picture of the complex wiring of gene regulatory networks that control vertebrate development...
The stability of the lens-specific Maf protein is regulated by fibroblast growth factor (FGF)/ERK signaling in lens fiber differentiationHaruki Ochi
Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma 630 0101, Japan
J Biol Chem 278:537-44. 2003..Taken together, these results indicate that FGF/ERK signaling negatively regulates the function of L-Maf in proliferative lens cells and that stabilization of the L-Maf protein is important for lens fiber differentiation...
Comparative expression analysis of the H3K27 demethylases, JMJD3 and UTX, with the H3K27 methylase, EZH2, in XenopusAkane Kawaguchi
Graduate School of Biological Sciences, Nara Institute of Science and Technology NAIST, Ikoma, Nara, Japan
Int J Dev Biol 56:295-300. 2012....
Evolution of a tissue-specific silencer underlies divergence in the expression of pax2 and pax8 paraloguesHaruki Ochi
Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5, Takayama, Ikoma, 630 0192, Japan
Nat Commun 3:848. 2012..We propose that silencer innovation, rather than enhancer degeneration, was crucial for the divergent expression of paralogues with pleiotropic enhancers inherited from their common progenitor...
Temporal expression of L-Maf and RaxL in developing chicken retina are arranged into mosaic patternHaruki Ochi
Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma 630 0101, Japan
Gene Expr Patterns 4:489-94. 2004..In contrast, RaxL positive cone cells are distributed in the outermost layer of ONL. Furthermore, tangential retinal sections showed that L-Maf positive rods and RaxL positive cones form a mosaic pattern during photoreceptor development...
L-Maf, a downstream target of Pax6, is essential for chick lens developmentHasan Mahmud Reza
Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma 630 0101, Japan
Mech Dev 116:61-73. 2002..Our results demonstrate that L-Maf is a downstream target of Pax6 and mediates Pax6 activity in developing lens cells...
