Akira Kido

Summary

Affiliation: Nara Medical University
Country: Japan

Publications

  1. ncbi request reprint Telomerase activity in benign bone tumors and tumor-like lesions
    A Kido
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Pathol Res Pract 195:753-7. 1999
  2. ncbi request reprint Possible contribution of aminopeptidase N (APN/CD13) to invasive potential enhanced by interleukin-6 and soluble interleukin-6 receptor in human osteosarcoma cell lines
    A Kido
    Department of Pathology, Otto von Guericke University Magdeburg, Germany
    Clin Exp Metastasis 17:857-63. 1999
  3. ncbi request reprint Telomerase activity in juxtacortical and conventional high-grade osteosarcomas: correlation with grade, proliferative activity and clinical response to chemotherapy
    Akira Kido
    Department of Pathology, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Cancer Lett 196:109-15. 2003
  4. doi request reprint Extent and contraindications for sacral amputation in patients with recurrent rectal cancer: a systematic literature review
    Akira Kido
    Department of Orthopedic Surgery, School of Medicine, Nara Medical University, 840 Shijo Cho, Kashihara, Nara 634 8522, Japan
    J Orthop Sci 16:286-90. 2011
  5. ncbi request reprint Inhibitory effect of antisense aminopeptidase N (APN/CD13) cDNA transfection on the invasive potential of osteosarcoma cells
    Akira Kido
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Clin Exp Metastasis 20:585-92. 2003
  6. ncbi request reprint Solitary tumor-like lesion at the metatarsophalangeal joint in a patient with rheumatoid arthritis: a case report
    Akira Kido
    Nara Medical University, Orthopedic Surgery, Kashihara, Nara 634 8521, Japan
    Foot Ankle Int 28:735-8. 2007
  7. ncbi request reprint Disease-specific expression patterns of proteases in synovial tissues
    Akira Kido
    Department of Orthopedic Surgery, Nara Medical University, Nara, Japan
    Pathol Res Pract 203:451-6. 2007
  8. doi request reprint Mesenchymal stem cells promote tumor engraftment and metastatic colonization in rat osteosarcoma model
    Shinji Tsukamoto
    Department of Orthopedic Surgery, Nara Medical University, 840 Shijo Cho, Kashihara, Japan
    Int J Oncol 40:163-9. 2012
  9. doi request reprint Osteogenesis of cryopreserved osteogenic matrix cell sheets
    Takamasa Shimizu
    Department of Orthopedic Surgery, Nara Medical University, Kashihara, Nara 634 8522, Japan
    Cryobiology 66:326-32. 2013
  10. ncbi request reprint Possible involvement of stem-like populations with elevated ALDH1 in sarcomas for chemotherapeutic drug resistance
    Kanya Honoki
    Department of Orthopedic Surgery, Nara Medical University, Kashihara, Nara 634 8521, Japan
    Oncol Rep 24:501-5. 2010

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Telomerase activity in benign bone tumors and tumor-like lesions
    A Kido
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Pathol Res Pract 195:753-7. 1999
    ..Determination of the telomerase status in benign lesions may contribute to a better understanding of the regulation mechanism of telomerase activity during progression of bone tumors...
  2. ncbi request reprint Possible contribution of aminopeptidase N (APN/CD13) to invasive potential enhanced by interleukin-6 and soluble interleukin-6 receptor in human osteosarcoma cell lines
    A Kido
    Department of Pathology, Otto von Guericke University Magdeburg, Germany
    Clin Exp Metastasis 17:857-63. 1999
    ..Cellular migration correlated highly with APN activity (r = 0.79, P < 0.002). These findings suggest that APN contributes to the invasive potential of human osteosarcomas enhanced by IL-6 and SIL-6R...
  3. ncbi request reprint Telomerase activity in juxtacortical and conventional high-grade osteosarcomas: correlation with grade, proliferative activity and clinical response to chemotherapy
    Akira Kido
    Department of Pathology, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Cancer Lett 196:109-15. 2003
    ..In malignant osteoblastic tumors, the biological significance of telomerase activation is different from that described for most epithelial cancers...
  4. doi request reprint Extent and contraindications for sacral amputation in patients with recurrent rectal cancer: a systematic literature review
    Akira Kido
    Department of Orthopedic Surgery, School of Medicine, Nara Medical University, 840 Shijo Cho, Kashihara, Nara 634 8522, Japan
    J Orthop Sci 16:286-90. 2011
    ..Previous reports have described differing extents of sacral resection. Most of these reports stated that high sacral involvement of the tumor is a contraindication for surgery; however, the basis for this is unclear...
  5. ncbi request reprint Inhibitory effect of antisense aminopeptidase N (APN/CD13) cDNA transfection on the invasive potential of osteosarcoma cells
    Akira Kido
    Department of Pathology, Otto von Guericke University, Magdeburg, Germany
    Clin Exp Metastasis 20:585-92. 2003
    ..These findings demonstrate that APN plays an active role in the cellular attachment and proteolytic degradation of the extracellular matrix in the metastatic process of osteosarcomas...
  6. ncbi request reprint Solitary tumor-like lesion at the metatarsophalangeal joint in a patient with rheumatoid arthritis: a case report
    Akira Kido
    Nara Medical University, Orthopedic Surgery, Kashihara, Nara 634 8521, Japan
    Foot Ankle Int 28:735-8. 2007
  7. ncbi request reprint Disease-specific expression patterns of proteases in synovial tissues
    Akira Kido
    Department of Orthopedic Surgery, Nara Medical University, Nara, Japan
    Pathol Res Pract 203:451-6. 2007
    ..Disease-specific protease activation pathways might exist, and cathepsin L can be a key enzyme for APL pathogenesis. Level of evidence: Prognostic study, level III (retrospective study)...
  8. doi request reprint Mesenchymal stem cells promote tumor engraftment and metastatic colonization in rat osteosarcoma model
    Shinji Tsukamoto
    Department of Orthopedic Surgery, Nara Medical University, 840 Shijo Cho, Kashihara, Japan
    Int J Oncol 40:163-9. 2012
    ....
  9. doi request reprint Osteogenesis of cryopreserved osteogenic matrix cell sheets
    Takamasa Shimizu
    Department of Orthopedic Surgery, Nara Medical University, Kashihara, Nara 634 8522, Japan
    Cryobiology 66:326-32. 2013
    ..This cryopreservation technique could be applied for hard tissue reconstruction to ease the cell preparation method prior to time of use...
  10. ncbi request reprint Possible involvement of stem-like populations with elevated ALDH1 in sarcomas for chemotherapeutic drug resistance
    Kanya Honoki
    Department of Orthopedic Surgery, Nara Medical University, Kashihara, Nara 634 8521, Japan
    Oncol Rep 24:501-5. 2010
    ..Although ALDH1 elevation was not sufficient for representing sarcoma stem cells, the efficient detoxification could contribute to the chemo-resistant properties of the stem-like sphere cells form human sarcoma...
  11. ncbi request reprint Growth inhibition and induction of apoptosis by 2-methoxyestradiol in rat osteosarcoma and malignant fibrous histiocytoma cell lines
    Hiromasa Fujii
    Department of Orthopedic Surgery, Nara Medical University, 840 Shijo Cho, Kashihara, Nara, Japan
    In Vivo 22:21-5. 2008
    ..These results suggested that the 2-ME-induced apoptosis of rat osteosarcoma and rat MFH cells was accompanied by caspase-3 activation through p16 induction...
  12. doi request reprint Secretory osteocalcin as a nondestructive osteogenic marker of tissue-engineered bone
    Manabu Akahane
    Department of Public Health, Health Management and Policy, Nara Medical University School of Medicine, Shijo cho 840, Kashihara, Nara, 634 8521, Japan
    J Orthop Sci 16:622-8. 2011
    ..We used a rat model to measure the secretory osteocalcin level in culture medium to verify that monitoring osteocalcin levels enables the selection of constructs with high osteogenic potential...
  13. doi request reprint Low concentrations of alendronate increase the local invasive potential of osteoblastic sarcoma cell lines via connexin 43 activation
    Kazuhiro Yoshitani
    Department of Orthopedic Surgery, Nara Medical University School of Medicine, 840 Shijo Cho, Kashihara, Nara 634 8522, Japan
    Pathol Res Pract 207:417-22. 2011
    ..Interestingly, oleamide, a potent connexin 43 inhibitor, had an inhibitory effect on the enhanced proliferation. Our data suggest that alendronate may enhance the proliferation of osteoblastic cell line through connexin 43 activation...
  14. ncbi request reprint Reduced expression of INK4a/ARF genes in stem-like sphere cells from rat sarcomas
    Hiromasa Fujii
    Department of Orthopedic Surgery, Nara Medical University, Kashihara, Nara 634 8521, Japan
    Biochem Biophys Res Commun 362:773-8. 2007
    ....
  15. ncbi request reprint Sphere-forming stem-like cell populations with drug resistance in human sarcoma cell lines
    Hiromasa Fujii
    Department of Orthopedic Surgery, Nara Medical University, Kashihara, Nara 634 8521, Japan
    Int J Oncol 34:1381-6. 2009
    ..These results indicate that human sarcoma cell lines contain stem-like cell populations with strong drug resistance, and DNA repair inhibitor could enhance the efficacy of chemo-drugs against sarcomas...
  16. ncbi request reprint Growth inhibition of rat osteosarcoma and malignant fibrous histiocytoma cells by tyrosine kinase inhibitor STI571
    Kazuhiro Yoshitani
    Department of Orthopedic Surgery, Nara Medical University, 840 Shijyo cho, Kashihara, Nara 634 8522, Japan
    In Vivo 17:255-8. 2003
    ..These data suggested that STI571 tyrosine kinase inhibitor plays a role in blocking or slowing the rate of growth of MFH and osteosarcoma cells expressing tyrosine kinase type receptor...
  17. ncbi request reprint Epiphyseal preservation and an intercalary vascularized fibular graft with hydroxyapatite composites. Reconstruction in metaphyseal osteosarcoma of the proximal tibia: a case report
    Kanya Honoki
    Department of Orthopedic Surgery, Nara Medical University, 840 Shijo Cho, Kashihara, Nara 634 8521, Japan
    Arch Orthop Trauma Surg 128:189-93. 2008
    ..BACKGROUND DATA AND OBJECTIVES: We present here a case report of a patient with metaphyseal osteosarcoma with a preserved epiphysis and reconstructed by a vascularized fibular graft and hydroxyapatite composites...
  18. pmc Comparison of gene expression profiling in sarcomas and mesenchymal stem cells identifies tumorigenic pathways in chemically induced rat sarcoma model
    Kanya Honoki
    Department of Orthopedic Surgery, Nara Medical University, 840 Shijo Cho, Kashihara 634 8521, Japan
    ISRN Oncol 2012:909453. 2012
    ..The current study indicated that these rat sarcomas could be a good model for their human counterparts and will provide the further insights into the molecular pathways and mechanisms involved in sarcoma pathogenesis...
  19. doi request reprint A successful reconstruction using a frozen autograft and a pedicled latissimus dorsi flap after a S12345B shoulder girdle resection in a patient with osteosarcoma
    Takamasa Shimizu
    Department of Orthopedic Surgery, Health Management and Policy, Nara Medical University School of Medicine, Nara, Japan
    J Reconstr Microsurg 28:155-9. 2012
    ..To our knowledge, this is the first report regarding a successful composite reconstruction after a S12345B shoulder girdle resection...
  20. doi request reprint Periosteal spindle cell hemangioma of the fibula: a case report
    Shinji Tsukamoto
    Department of Orthopaedic Surgery, Nara Medical University, 840, Shijo cho, Kashihara City, Nara, 634 8521, Japan
    Skeletal Radiol 42:1165-8. 2013
    ..Excision of the fibula was a reasonable course of management in this case because these patients usually maintain good function. Reports of additional cases will be required to determine the most appropriate treatment for this tumor. ..
  21. pmc Epithelioid sarcoma of the forearm arising from perineural sheath of median nerve mimicking carpal tunnel syndrome
    Hiromasa Fujii
    Department of Orthopedic Surgery, Nara Medical University, 840 Shijo Cho, Kashihara, Nara 634 8521, Japan
    Sarcoma 2009:595391. 2009
    ..The patient returned to his original vocation and alive with continuous disease free at 3.5-year follow-up since initial treatment...
  22. ncbi request reprint Prognostic significance of p16 INK4a alteration for Ewing sarcoma: a meta-analysis
    Kanya Honoki
    Department of Orthopedic Surgery, Nara Medical University, Nara, Japan
    Cancer 110:1351-60. 2007
    ..The objective of the current study was to evaluate whether the presence of p16(INK4a) alteration is associated with a poorer prognosis in patients with Ewing sarcomas...
  23. ncbi request reprint Adamantinoma-like Ewing's sarcoma with EWS-FLI1 fusion gene: a case report
    Hiromasa Fujii
    Department of Orthopedic Surgery, Nara Medical University, 840 Shijo Cho, Kashihara, Nara 634 8521, Japan
    Virchows Arch 449:579-84. 2006
    ..After wide excision and high-dose chemotherapy with peripheral blood stem cell transfusion, the patient has been well and continuously event-free for 3 years since the initial diagnosis...
  24. ncbi request reprint Differential expression of cytokines in rat osteosarcoma and malignant fibrous histiocytoma cell lines induced by 4-(hydroxyamino)quinoline-1-oxide
    Kanya Honoki
    Department of Orthopedic Surgery, Nara Medical University, Kashihara, Nara, Japan
    Mol Carcinog 33:81-7. 2002
    ....
  25. doi request reprint Scaffold-free cell sheet injection results in bone formation
    Manabu Akahane
    Department of Public Health, Health Management and Policy, Nara Medical University School of Medicine, Kashihara, Nara 634 8521, Japan
    J Tissue Eng Regen Med 4:404-11. 2010
    ..Owing to its usage of a needle for fabrication of in vivo bone tissue, this injection method can be applied as a minimally invasive approach for hard tissue reconstruction...
  26. doi request reprint Statistical analysis of fatal bleeding pelvic fracture patients with severe associated injuries
    Akira Kido
    Department of Orthopedic Surgery, Nara Medical University, Kashihara, Nara, Japan
    J Orthop Sci 13:21-4. 2008
    ..To gain deeper etiological insights into this injury, we investigated the specific risk factors associated with the high mortality rate...
  27. ncbi request reprint Genetic analysis of human complement factor H polymorphisms
    Rie Susukida
    Department of Legal Medicine, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Shimokato, Yamanashi, Japan
    Electrophoresis 28:309-16. 2007
    ..This method could be useful for studies on genetic disease associated with these mutations...