Takashi Hashimoto

Summary

Affiliation: Nara Institute of Science and Technology
Country: Japan

Publications

  1. ncbi request reprint Dynamics and regulation of plant interphase microtubules: a comparative view
    Takashi Hashimoto
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama cho, Ikoma, Nara 630 0192, Japan
    Curr Opin Plant Biol 6:568-76. 2003
  2. ncbi request reprint New genes in alkaloid metabolism and transport
    Takashi Hashimoto
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara 630 0192, Japan
    Curr Opin Biotechnol 14:163-8. 2003
  3. pmc Molecular genetic analysis of left-right handedness in plants
    Takashi Hashimoto
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara 630 0101, Japan
    Philos Trans R Soc Lond B Biol Sci 357:799-808. 2002
  4. ncbi request reprint [Microtubules and cell elongation]
    Takashi Hashimoto
    Tanpakushitsu Kakusan Koso 47:1620-5. 2002
  5. doi request reprint Nuclear-localized subtype of end-binding 1 protein regulates spindle organization in Arabidopsis
    Shinichiro Komaki
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630 0192, Japan
    J Cell Sci 123:451-9. 2010
  6. doi request reprint A comprehensive expression analysis of the Arabidopsis MICRORNA165/6 gene family during embryogenesis reveals a conserved role in meristem specification and a non-cell-autonomous function
    Shunsuke Miyashima
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara, 630 0192 Japan
    Plant Cell Physiol 54:375-84. 2013
  7. doi request reprint Arabidopsis SPIRAL2 promotes uninterrupted microtubule growth by suppressing the pause state of microtubule dynamics
    Maki Yao
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara, Japan
    J Cell Sci 121:2372-81. 2008
  8. doi request reprint Tobacco MYC2 regulates jasmonate-inducible nicotine biosynthesis genes directly and by way of the NIC2-locus ERF genes
    Tsubasa Shoji
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara, Japan
    Plant Cell Physiol 52:1117-30. 2011
  9. pmc Plant-specific microtubule-associated protein SPIRAL2 is required for anisotropic growth in Arabidopsis
    Tsubasa Shoji
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma 630 0192, Japan
    Plant Physiol 136:3933-44. 2004
  10. pmc Helical microtubule arrays in a collection of twisting tubulin mutants of Arabidopsis thaliana
    Takashi Ishida
    Nara Institute of Science and Technology, Graduate School of Biological Sciences, Ikoma, Nara 630 0192, Japan
    Proc Natl Acad Sci U S A 104:8544-9. 2007

Collaborators

Detail Information

Publications57

  1. ncbi request reprint Dynamics and regulation of plant interphase microtubules: a comparative view
    Takashi Hashimoto
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama cho, Ikoma, Nara 630 0192, Japan
    Curr Opin Plant Biol 6:568-76. 2003
    ..Comparison with fungal and animal microtubules highlights both conserved and unique mechanisms for the regulation of the microtubule cytoskeleton in plants...
  2. ncbi request reprint New genes in alkaloid metabolism and transport
    Takashi Hashimoto
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara 630 0192, Japan
    Curr Opin Biotechnol 14:163-8. 2003
    ....
  3. pmc Molecular genetic analysis of left-right handedness in plants
    Takashi Hashimoto
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara 630 0101, Japan
    Philos Trans R Soc Lond B Biol Sci 357:799-808. 2002
    ....
  4. ncbi request reprint [Microtubules and cell elongation]
    Takashi Hashimoto
    Tanpakushitsu Kakusan Koso 47:1620-5. 2002
  5. doi request reprint Nuclear-localized subtype of end-binding 1 protein regulates spindle organization in Arabidopsis
    Shinichiro Komaki
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630 0192, Japan
    J Cell Sci 123:451-9. 2010
    ..These results suggest that a plant-specific EB1 subtype has evolved to function preferentially on the spindle microtubules by accumulating in the prophase nucleus...
  6. doi request reprint A comprehensive expression analysis of the Arabidopsis MICRORNA165/6 gene family during embryogenesis reveals a conserved role in meristem specification and a non-cell-autonomous function
    Shunsuke Miyashima
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara, 630 0192 Japan
    Plant Cell Physiol 54:375-84. 2013
    ....
  7. doi request reprint Arabidopsis SPIRAL2 promotes uninterrupted microtubule growth by suppressing the pause state of microtubule dynamics
    Maki Yao
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara, Japan
    J Cell Sci 121:2372-81. 2008
    ..We propose that the SPR2-family proteins act on the pause state to facilitate a transition to microtubule growth...
  8. doi request reprint Tobacco MYC2 regulates jasmonate-inducible nicotine biosynthesis genes directly and by way of the NIC2-locus ERF genes
    Tsubasa Shoji
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara, Japan
    Plant Cell Physiol 52:1117-30. 2011
    ..These results indicate that NtMYC2 controls nicotine biosynthesis genes in two combinatorial ways, by directly binding the G-box in the target promoters and by up-regulating the NIC2-locus ERF genes...
  9. pmc Plant-specific microtubule-associated protein SPIRAL2 is required for anisotropic growth in Arabidopsis
    Tsubasa Shoji
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma 630 0192, Japan
    Plant Physiol 136:3933-44. 2004
    ..These results suggest that SPR2 is a novel microtubule-associated protein and is required for proper microtubule function involved in anisotropic growth...
  10. pmc Helical microtubule arrays in a collection of twisting tubulin mutants of Arabidopsis thaliana
    Takashi Ishida
    Nara Institute of Science and Technology, Graduate School of Biological Sciences, Ikoma, Nara 630 0192, Japan
    Proc Natl Acad Sci U S A 104:8544-9. 2007
    ..This comprehensive analysis of tubulin mutations provides insights into the mechanism by which tubulin structures influence microtubule dynamics and organization...
  11. doi request reprint Non-functionalization of two CYP82E nicotine N-demethylase genes abolishes nornicotine formation in Nicotiana langsdorffii
    Phattharaporn Pakdeechanuan
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Takayama 8916 5, Ikoma, Nara, 630 0192 Japan
    Plant Cell Physiol 53:2038-46. 2012
    ....
  12. ncbi request reprint Role of the SPIRAL1 gene family in anisotropic growth of Arabidopsis thaliana
    Keiji Nakajima
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara, 630 0192 Japan
    Plant Cell Physiol 47:513-22. 2006
    ....
  13. pmc Multidrug and toxic compound extrusion-type transporters implicated in vacuolar sequestration of nicotine in tobacco roots
    Tsubasa Shoji
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630 0192, Japan
    Plant Physiol 149:708-18. 2009
    ..The results imply that these MATE-type proteins transport tobacco alkaloids from the cytosol into the vacuole in exchange for protons in alkaloid-synthesizing root cells...
  14. doi request reprint Why does anatabine, but not nicotine, accumulate in jasmonate-elicited cultured tobacco BY-2 cells?
    Tsubasa Shoji
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara, 630 0192 Japan
    Plant Cell Physiol 49:1209-16. 2008
    ..These results identify the transcriptional regulation of MPO as a critical rate-limiting step that restricts nicotine formation in cultured tobacco BY-2 cells...
  15. doi request reprint Mitogen-activated protein kinase phosphatase PHS1 is retained in the cytoplasm by nuclear extrusion signal-dependent and independent mechanisms
    Jaromir Pytela
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, 630 0192 Nara, Japan
    Planta 231:1311-22. 2010
    ..A nuclear export signal identified in the C-terminal tail also contributes to the robust cytoplasmic retention of PHS1...
  16. doi request reprint Recruitment of a duplicated primary metabolism gene into the nicotine biosynthesis regulon in tobacco
    Tsubasa Shoji
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Takayama 8916 5, Ikoma, Nara 630 0192, Japan
    Plant J 67:949-59. 2011
    ....
  17. pmc SPIRAL1 encodes a plant-specific microtubule-localized protein required for directional control of rapidly expanding Arabidopsis cells
    Keiji Nakajima
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630 0192, Japan
    Plant Cell 16:1178-90. 2004
    ..These observations suggest that SPR1 is a plant-specific MT-localized protein required for the maintenance of growth anisotropy in rapidly elongating cells...
  18. ncbi request reprint Salt stress affects cortical microtubule organization and helical growth in Arabidopsis
    Tsubasa Shoji
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara, 630 0192 Japan
    Plant Cell Physiol 47:1158-68. 2006
    ..These results suggest that cytoplasmic salt imbalance caused by insufficient SOS1 activity compromises cortical microtubule functions in which microtubule-localized SPIRAL1 is specifically involved...
  19. ncbi request reprint Altered microtubule dynamics by expression of modified alpha-tubulin protein causes right-handed helical growth in transgenic Arabidopsis plants
    Tatsuya Abe
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara 630 0192, Japan
    Plant J 43:191-204. 2005
    ....
  20. pmc A semidominant mutation in an Arabidopsis mitogen-activated protein kinase phosphatase-like gene compromises cortical microtubule organization
    Kuniko Naoi
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, 630 0192, Japan
    Plant Cell 16:1841-53. 2004
    ..We propose that the PHS1 phosphatase regulates more than one MAPK and that a subset of its target kinases is involved in the organization of cortical microtubules...
  21. doi request reprint Jasmonate-induced nicotine formation in tobacco is mediated by tobacco COI1 and JAZ genes
    Tsubasa Shoji
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara, 630 0192 Japan
    Plant Cell Physiol 49:1003-12. 2008
    ..These results indicate that jasmonate-triggered, COI1-mediated degradation of JAZ repressors activates transcriptional regulation of nicotine biosynthesis genes in tobacco roots...
  22. doi request reprint A mutation in the Arabidopsis gamma-tubulin-containing complex causes helical growth and abnormal microtubule branching
    Masayoshi Nakamura
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630 0192, Japan
    J Cell Sci 122:2208-17. 2009
    ..These results show that Arabidopsis GCP2 has an important role in precisely positioning the gamma-tubulin-containing complex on pre-existing microtubules and in the proper organization of cortical arrays...
  23. pmc Clustered transcription factor genes regulate nicotine biosynthesis in tobacco
    Tsubasa Shoji
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara, Japan
    Plant Cell 22:3390-409. 2010
    ....
  24. doi request reprint A PIP-family protein is required for biosynthesis of tobacco alkaloids
    Masataka Kajikawa
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama cho, Ikoma, Nara, 630 0192, Japan
    Plant Mol Biol 69:287-98. 2009
    ..We propose that the tobacco A622-like reductases of the PIP family are involved in either the formation of a nicotinic acid-derived precursor or the final condensation reaction of tobacco alkaloids...
  25. ncbi request reprint Microtubule defects and cell morphogenesis in the lefty1lefty2 tubulin mutant of Arabidopsis thaliana
    Tatsuya Abe
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara, 630 0192 Japan
    Plant Cell Physiol 45:211-20. 2004
    ..These results suggest that left-handed twisted elongation is an intermediate state that leads to full isotropic expansion as the cortical microtubules are increasingly destabilized...
  26. doi request reprint A GAL4-based targeted activation tagging system in Arabidopsis thaliana
    Takamitsu Waki
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara, 630 0192, Japan
    Plant J 73:357-67. 2013
    ..These results indicate that GAL4/UAS activation tagging is a powerful method for identifying genes with biological functions that are not readily identified by conventional screening methods...
  27. pmc Vacuole-localized berberine bridge enzyme-like proteins are required for a late step of nicotine biosynthesis in tobacco
    Masataka Kajikawa
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630 0192, Japan
    Plant Physiol 155:2010-22. 2011
    ..These results indicate that BBLs are involved in a late oxidation step subsequent to the pyridine ring condensation reaction in the biosynthesis of tobacco alkaloids...
  28. ncbi request reprint An Arabidopsis thaliana tubulin mutant with conditional root-skewing phenotype
    Takashi Ishida
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara 630 0192, Japan
    J Plant Res 120:635-40. 2007
    ..These results suggest that compromised microtubules in wild-type and mutant roots are qualitatively distinct and affect skewing direction differently...
  29. doi request reprint Root-to-shoot translocation of alkaloids is dominantly suppressed in Nicotiana alata
    Phattharaporn Pakdeechanuan
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Takayama 8916 5, Ikoma, Nara 630 0192, Japan
    Plant Cell Physiol 53:1247-54. 2012
    ..These results indicate that a mechanism to retain tobacco alkaloids within the root organ has evolved in N. alata, which may represent an interesting strategy to control the distribution of secondary products within a whole plant...
  30. doi request reprint ARGONAUTE1 acts in Arabidopsis root radial pattern formation independently of the SHR/SCR pathway
    Shunsuke Miyashima
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara 630 0192, Japan
    Plant Cell Physiol 50:626-34. 2009
    ....
  31. doi request reprint Non-cell-autonomous microRNA165 acts in a dose-dependent manner to regulate multiple differentiation status in the Arabidopsis root
    Shunsuke Miyashima
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara 630 0192, Japan
    Development 138:2303-13. 2011
    ....
  32. ncbi request reprint Molecular cloning of N-methylputrescine oxidase from tobacco
    Akira Katoh
    Nara Institute of Science and Technology, Graduate School of Biological Sciences, 8916 5 Takayama, Ikoma, Nara, 630 0192, Japan
    Plant Cell Physiol 48:550-4. 2007
    ..These results indicate that MPO evolved from general diamine oxidases to function effectively in nicotine biosynthesis...
  33. pmc Early steps in the biosynthesis of NAD in Arabidopsis start with aspartate and occur in the plastid
    Akira Katoh
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630 0192, Japan
    Plant Physiol 141:851-7. 2006
    ..An analysis of functional green fluorescent protein-fused constructs and in vitro assays of uptake into isolated chloroplasts demonstrated that these three enzymes are located in the plastid...
  34. doi request reprint Microtubule and katanin-dependent dynamics of microtubule nucleation complexes in the acentrosomal Arabidopsis cortical array
    Masayoshi Nakamura
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma 630 0192, Japan
    Nat Cell Biol 12:1064-70. 2010
    ....
  35. doi request reprint Arabidopsis GCP3-interacting protein 1/MOZART 1 is an integral component of the γ-tubulin-containing microtubule nucleating complex
    Masayoshi Nakamura
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630 0192, Japan
    Plant J 71:216-25. 2012
    ..These results indicate that GIP1/MOZART1 is an integral component of a subset of the Arabidopsis γ-tubulin complexes...
  36. ncbi request reprint Expression patterns of two tobacco isoflavone reductase-like genes and their possible roles in secondary metabolism in tobacco
    Tsubasa Shoji
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Japan
    Plant Mol Biol 50:427-40. 2002
    ..The A622 expression patterns were qualitatively similar to those of putrescine N-methyltransferase, the first enzyme in nicotine biosynthesis, suggesting that A622 may function in the metabolism of nicotine or related alkaloids...
  37. ncbi request reprint Low concentrations of propyzamide and oryzalin alter microtubule dynamics in Arabidopsis epidermal cells
    Masayoshi Nakamura
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara, 630 0192 Japan
    Plant Cell Physiol 45:1330-4. 2004
    ..A reduction in microtubule dynamic turnover may underlie the drug-induced rearrangement of cortical arrays...
  38. doi request reprint The Arabidopsis RWP-RK protein RKD4 triggers gene expression and pattern formation in early embryogenesis
    Takamitsu Waki
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma, Nara 630 0192, Japan
    Curr Biol 21:1277-81. 2011
    ..Strikingly, induced overexpression of RKD4 primed somatic cells for embryogenesis independently of external growth regulators. These results reveal that RKD4 is a novel key regulator of the earliest stage of plant development...
  39. ncbi request reprint Microtubule basis for left-handed helical growth in Arabidopsis
    Siripong Thitamadee
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Takayama 8916 5, Ikoma 630 0101, Japan
    Nature 417:193-6. 2002
    ..The cortical microtubules in the mutants had increased sensitivity to microtubule-specific drugs. These results suggest that reduced microtubule stability can produce left-handed helical growth in plants...
  40. ncbi request reprint Twisted growth and organization of cortical microtubules
    Takashi Ishida
    Nara Institute of Science and Technology, Graduate School of Biological Sciences, 8916 5 Takayama, Ikoma, Nara 630 0192, Japan
    J Plant Res 120:61-70. 2007
    ..Molecular and cell biological studies on twisting mutants will lead to better understanding on how wild-type plant cells utilize the microtubule cytoskeleton to initiate and rigorously maintain straight growth...
  41. ncbi request reprint Cortical control of plant microtubules
    Takashi Hashimoto
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630 0192, Japan
    Curr Opin Plant Biol 9:5-11. 2006
    ..The ROP family of small GTPases and the mitogen-activated protein kinase pathways have emerged as key players that mediate the cortical control of plant microtubules...
  42. ncbi request reprint Molecular biology of pyridine nucleotide and nicotine biosynthesis
    Akira Katoh
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630 0192, Japan
    Front Biosci 9:1577-86. 2004
    ..Gene expression studies in tobacco suggest that part of the NAD pathway is coordinately regulated with nicotine biosynthesis...
  43. pmc Divergent DNA-binding specificities of a group of ETHYLENE RESPONSE FACTOR transcription factors involved in plant defense
    Tsubasa Shoji
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630 0101, Japan
    Plant Physiol 162:977-90. 2013
    ..Divergent DNA-binding specificities of the ERFs may have arisen through mutational changes of these amino acid residues...
  44. ncbi request reprint Conserved factors regulate signalling in Arabidopsis thaliana shoot and root stem cell organizers
    Ananda K Sarkar
    Institute of Biology III, University of Freiburg, Schanzlestrasse 1, 79104 Freiburg, Germany
    Nature 446:811-4. 2007
    ..Importantly, both WOX5 and WUS maintain stem cells in either a root or shoot context. Together, our data indicate that stem cell maintenance signalling in both meristems employs related regulators...
  45. ncbi request reprint An epidermoid cyst with atypical keratinocytes in the lowermost portion of the cyst wall
    Fumitake Ono
    Department of Dermatology, Kurume University School of Medicine, 67 Asahi Machi, Kurume 830 0011, Japan
    Kurume Med J 50:67-70. 2003
    ....
  46. ncbi request reprint Alkaloids in plants and root cultures of Atropa belladonna overexpressing putrescine N-methyltransferase
    Grit Rothe
    Institute of Pharmaceutical Biology, Martin Luther University Halle Wittenberg, Hoher Weg 8, D 06120 Halle Saale, Germany
    J Exp Bot 54:2065-70. 2003
    ..1 microM auxin reduced calystegine levels in control roots, while in pmt-overexpressing roots all alkaloids remained unaltered. Expression level of pmt alone is apparently not limiting for tropane alkaloid formation in A. belladonna...
  47. ncbi request reprint Gamma-tubulin distribution during cortical microtubule reorganization at the M/G1 interface in tobacco BY-2 cells
    Fumi Kumagai
    Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan
    Eur J Cell Biol 82:43-51. 2003
    ..Based on the results, it was confirmed that daughter nuclear surfaces acted as origins of cortical microtubules, and that further reorganization occurred on the cell cortex...
  48. pmc Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator
    Sailesh Surapureddi
    Department of Pathology, Northwestern University, The Feinberg School of Medicine, Chicago, IL 60611, USA
    Proc Natl Acad Sci U S A 99:11836-41. 2002
    ..The composition of this complex may provide insight into the basis of tissue and species sensitivity to peroxisome proliferators...
  49. ncbi request reprint Molecular cloning, expression and characterization of tropinone reductase II, an enzyme of the SDR family in Solanum tuberosum (L.)
    Ronald Keiner
    Institut fur Pharmazeutische Biologie, Martin Luther Universitat Halle Wittenberg, Halle Saale, Germany
    Plant Mol Biol 48:299-308. 2002
    ..The distribution of the TRII transcript in comparison with the calystegine concentrations in the tissues suggests transport of calystegines or their precursors between potato organs...
  50. ncbi request reprint Caffeine inhibits cell proliferation by G0/G1 phase arrest in JB6 cells
    Takashi Hashimoto
    Hormel Institute, University of Minnesota, Austin, Minnesota 55912, USA
    Cancer Res 64:3344-9. 2004
    ..The inhibitory mechanism may be due to the inhibition of cell growth signal-induced activation of cdk4, which may be involved in the inhibition of carcinogenesis in vivo...
  51. ncbi request reprint Negative fallout from public sentiment in Japan
    Kazuo N Watanabe
    Nat Biotechnol 22:943. 2004
  52. ncbi request reprint Ahnak/Desmoyokin is dispensable for proliferation, differentiation, and maintenance of integrity in mouse epidermis
    Michiyoshi Kouno
    Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan
    J Invest Dermatol 123:700-7. 2004
    ..These results lead us to conclude that Ahnak/Desmoyokin deficiency has only a minimal effect on epidermal cell adhesion, tumorigenesis, cell proliferation and differentiation, and overall mouse development...
  53. ncbi request reprint Tea catechin suppresses adipocyte differentiation accompanied by down-regulation of PPARgamma2 and C/EBPalpha in 3T3-L1 cells
    Takashi Furuyashiki
    Department of Biofunctional Chemistry, Graduate School of Science and Technology, Kobe University, Japan
    Biosci Biotechnol Biochem 68:2353-9. 2004
    ..Thus, catechin suppressed adipocyte differentiation accompanied by the down-regulation of PPARgamma2, C/EBPalpha, and GLUT4. These results suggest that tea catechin prevents obesity through the suppression of adipocyte differentiation...
  54. ncbi request reprint Purification and characterization of plant dynamin from tobacco BY-2 cells
    Takahiro Hamada
    Department of Life Science, Graduate School of Life Science, University of Hyogo, Harima Science Park City, Hyogo, 678 1297 Japan
    Plant Cell Physiol 47:1175-81. 2006
    ..When GDP was added to the NtDRP3 fraction, the filaments disappeared and many particles appeared. Biochemical analysis revealed that NtDRP3 could bind to and bundle both microtubules and actin filaments in vitro...
  55. ncbi request reprint Synaptic adhesion molecule OBCAM; synaptogenesis and dynamic internalization
    Mayumi Yamada
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Brain Res 1165:5-14. 2007
    ..These results indicate that OBCAM is a synaptic cell adhesion molecule concerning synaptogenesis and its surface localization is dynamically regulated in response to neuronal activity...
  56. ncbi request reprint Desmosome-binding antibody KM48 recognises an extracellular antigen different from desmosomal cadherins Dsg 1-3 and Dsc 1-3
    Stephane Duhieu
    Department of Dermatology, Hopital Edouard Herriot, Universite Claude Bernard, EA3732 CNRS, Lyon 1, France
    Eur J Dermatol 15:80-4. 2005
    ..This protein, recognised by KM48 monoclonal antibody, is likely to be involved in the processes of keratinocyte differentiation, desmosome turnover and epidermal cohesion...
  57. doi request reprint IgLON cell adhesion molecule Kilon is a crucial modulator for synapse number in hippocampal neurons
    Takashi Hashimoto
    Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
    Brain Res 1224:1-11. 2008
    ..These results demonstrate the alteration of modulatory function of Kilon for the number of dendritic synapses concomitant with changes in its localization and detergent solubility during neuronal culture development...