Research Topics
Species | Hideo AsadaSummaryAffiliation: Nara Medical University Country: Japan Publications
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Detail Information
Publications
Hypersensitivity to mosquito bites: a unique pathogenic mechanism linking Epstein-Barr virus infection, allergy and oncogenesisHideo Asada
Department of Dermatology, Nara Medical University, 840 Shijo Cho, Kashihara, Nara 634 8521, Japan
J Dermatol Sci 45:153-60. 2007....
An inverse correlation of VZV skin-test reaction, but not antibody, with severity of herpes zoster skin symptoms and zoster-associated painHideo Asada
Department of Dermatology, Nara Medical University School of Medicine, Nara, Japan
J Dermatol Sci 69:243-9. 2013..Cell-mediated immunity (CMI) has been considered to be related to the development of herpes zoster (HZ). However, there have been no large-scale prospective studies on the relationship between VZV-specific CMI and severity of HZ...
Evaluation of provocation test monitoring palmoplantar temperature with the use of thermography for diagnosis of focal tonsillar infection in palmoplantar pustulosisHideo Asada
Department of Dermatology, Nara Medical University, 840 Shijo cho Kashihara, 634 8522, Nara, Japan
J Dermatol Sci 32:105-13. 2003..Since focal tonsillar infections are often associated with palmoplantar pustulosis (PPP), provocation tests have been performed for preoperative evaluation of tonsillectomy. However, these tests have not been fully established...
CD4+ T-lymphocyte-induced Epstein-Barr virus reactivation in a patient with severe hypersensitivity to mosquito bites and Epstein-Barr virus-infected NK cell lymphocytosisHideo Asada
Department of Dermatology, Nara Medical University, Kashihara, Japan
Arch Dermatol 139:1601-7. 2003..However, the induction mechanism of HMB is still unclear...
Mosquito salivary gland extracts induce EBV-infected NK cell oncogenesis via CD4 T cells in patients with hypersensitivity to mosquito bitesHideo Asada
Department of Dermatology, Nara Medical University School of Medicine, Karshihara, Japan
J Invest Dermatol 125:956-61. 2005..These results suggest that mosquito bites can induce expression of the viral oncogene LMP1 in NK cells via mosquito antigen-specific CD4+ T cells, which is involved in the oncogenesis of NK cells in vivo...
Adjuvant effect of lipopolysaccharide on the induction of contact hypersensitivity to haptens in miceShoko Yokoi
Department of Dermatology, Nara Medical University, Kashihara, Nara, Japan
J Dermatol Sci 53:120-8. 2009..The MyD88-independent pathway downstream of TLR4 leads to functional dendritic cell (DC) maturation, although LPS-induced cytokine production from DCs is MyD88-dependent...
Enhanced T-cell response to mosquito extracts by NK cells in hypersensitivity to mosquito bites associated with EBV infection and NK cell lymphocytosisYoshiki Tokura
Department of Dermatology, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahata nishi ku, Kitakyushu 807 8555, Japan
Cancer Sci 96:519-26. 2005..We suggest that the CD4+ T cell serving as the primary responder to MSG antigen and the NK cell functioning as the enhancer are both pathogenic in the development of HMB...
Regulatory effects of antihistamines on the responses to staphylococcal enterotoxin B of human monocyte-derived dendritic cells and CD4+ T cellsHideyuki Iida
Department of Dermatology, Nara Medical University, Kashihara, Japan
J Dermatol Sci 52:31-8. 2008..Dendritic cells (DCs) drive polarization of naive T cells into Th1 or Th2 subsets, and are also likely to be involved in AD pathogenesis...
Relationship among human herpesvirus 6 reactivation, serum interleukin 10 levels, and rash/graft-versus-host disease after allogeneic stem cell transplantationKana Kitamura
Department of Dermatology, Nara Medical University, Nara, Japan
J Am Acad Dermatol 58:802-9. 2008..The relationship between herpesvirus reactivation and graft-versus-host disease (GVHD) after allogeneic stem cell transplantation (allo-SCT) is unclear...
Role for connexin 26 in metastasis of human malignant melanoma: communication between melanoma and endothelial cells via connexin 26Mamiko Saito-Katsuragi
Department of Dermatology, Nara Medical University, Kashihara, Nara, Japan
Cancer 110:1162-72. 2007..The objective of the study was to investigate the role Cx26 plays in the metastasis of human melanoma cells, focusing on the communication between melanoma cells and endothelial cells...
Paraneoplastic pemphigus presenting as erythrodermic lichenoid dermatitis with concomitant features of pemphigus foliaceusTakaya Fukumoto
Department of Dermatology, Nara Medical University School of Medicine, Nara, Japan
J Dermatol 34:645-9. 2007....
Induction of beta-defensin 3 in keratinocytes stimulated by bacterial lipopeptides through toll-like receptor 2Yasuyuki Sumikawa
Department of Dermatology, Course of Molecular Medicine, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan
Microbes Infect 8:1513-21. 2006..The grafted skin from TLR2-deficient mice resulted in erosion. These studies strongly suggest that the TLR2-MyD88-dependent pathway in keratinocytes is essential for antimicrobial activity in vivo...
Identification of thymus and activation-regulated chemokine (TARC/CCL17) as a potential marker for early indication of disease and prediction of disease activity in drug-induced hypersensitivity syndrome (DIHS)/drug rash with eosinophilia and systemic symKohei Ogawa
Department of Dermatology, Nara Medical University School of Medicine, Nara, Japan
J Dermatol Sci 69:38-43. 2013..Thymus and activation-regulated chemokine (TARC/CCL17) is a family of CC chemokines known to play an important role in Th2-mediated immune-inflammatory processes...
Selective induction of antimicrobial peptides from keratinocytes by staphylococcal bacteriaRie Ommori
Department of Dermatology, Nara Medical University, Kashihara, Nara 634 8522, Japan
Microb Pathog 56:35-9. 2013..The secreted products of S. aureus and S. epidermidis differentially induced subtypes of hBD through different receptors, which may be associated with the difference in virulence between these two bacteria...
Juvenile-onset hypergammaglobulinemic purpura and fetal congenital heart blockMaki Maeda Tanaka
Department of Dermatology, Perinatal Medical Center, Nara Medical University Hospital, Kashihara City, Nara 634 8522, Japan
J Dermatol 33:714-8. 2006..Screening for these autoantibodies is important and could be used as a marker to identify and manage high-risk pregnancies...
Bucillamine-induced toxic epidermal necrolysis and fixed drug eruptionAtsuko Izumi
Department of Dermatology, Nara Medical University School of Medicine, Nara, Japan
J Dermatol 32:397-401. 2005..These cases highlight the importance of considering fixed drug eruption as well as TEN in the differential diagnosis of bucillamine-induced bullous drug eruption...
Ampicillin-induced cutaneous eruption associated with Epstein-Barr virus reactivationMamiko Saito-Katsuragi
J Am Acad Dermatol 52:S127-8. 2005
A possible mechanism of NK cell-lineage granular lymphocyte proliferative disorder (NK-GLPD) in a patient with chronic active Epstein-Barr virus infection (CAEBV) and severe hypersensitivity to mosquito bites (SHMB)Shiro Ohshima
Department of Molecular Medicine, Osaka University Medical School, Suita
Intern Med 41:651-6. 2002....
Childhood epidermolysis bullosa acquisita with autoantibodies against all 3 structural domains of type VII collagenTakaya Fukumoto
J Am Acad Dermatol 50:480-2. 2004
Enhancement of immunity against VZV by giving live varicella vaccine to the elderly assessed by VZV skin test and IAHA, gpELISA antibody assayMichiaki Takahashi
Research Foundation for Microbial Diseases of Osaka University, Suita, Osaka, Japan
Vaccine 21:3845-53. 2003..Although this study was uncontrolled open study, the results suggest that administering live varicella vaccine to the elderly is effective for enhancing immunity, particularly CMI to VZV...
