Haruo Nakamura

Summary

Country: Japan

Publications

  1. ncbi request reprint Clinical characteristics of asthmatic patients prescribed various beta-agonist metered-dose inhalers at Yamagata University Hospital
    F Ojima
    Department of Pharmacy, Yamagata University Hospital, Yamagata 990-9585, Japan
    Yakugaku Zasshi 121:79-84. 2001
  2. ncbi request reprint Histological changes of thyroid tissues in patients with liver cirrhosis
    R Gemma
    Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan
    Endocr J 48:535-42. 2001
  3. ncbi request reprint Management of severe subarachnoid hemorrhage; significance of assessment of both neurological and systemic insults at acute stage
    A Satoh
    Department of Neurosurgery, Saitama Medical School, Saitama, Japan
    Acta Neurochir Suppl 94:59-63. 2005
  4. doi request reprint Effect of lipid-lowering therapy with atorvastatin on atherosclerotic aortic plaques: a 2-year follow-up by noninvasive MRI
    Atsushi Yonemura
    National Defense Medical College, Tokyo, Japan
    Eur J Cardiovasc Prev Rehabil 16:222-8. 2009
  5. ncbi request reprint Primary prevention of cardiovascular diseases among hypercholesterolemic Japanese with a low dose of pravastatin
    H Nakamura
    Mitsukoshi Health and Welfare Foundation, 1 24 1 Nishi shinjuku, Tokyo 160 0023, Japan
    Atheroscler Suppl 8:13-7. 2007
  6. ncbi request reprint Primary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): a prospective randomised controlled trial
    Haruo Nakamura
    Mitsukoshi Health and Welfare Foundation, Tokyo, Japan
    Lancet 368:1155-63. 2006
  7. doi request reprint Pravastatin and cardiovascular risk in moderate chronic kidney disease
    Haruo Nakamura
    Mitsukoshi Health and Welfare Foundation, STEC Jyoho Building, 1 24 1 Nishishinjuku Shinjuku, Tokyo, 160 0023, Japan
    Atherosclerosis 206:512-7. 2009
  8. ncbi request reprint The relationship between the effect of pravastatin and risk factors for coronary heart disease in Japanese patients with hypercholesterolemia
    Toshitsugu Ishikawa
    Occupational Health Department, Sony Corporation, Tokyo, Japan
    Circ J 72:1576-82. 2008
  9. doi request reprint Low-dose pravastatin and age-related differences in risk factors for cardiovascular disease in hypercholesterolaemic Japanese: analysis of the management of elevated cholesterol in the primary prevention group of adult Japanese (MEGA study)
    Noriaki Nakaya
    Nakaya Clinic, Tokyo, Japan
    Drugs Aging 28:681-92. 2011
  10. doi request reprint The effect of low-dose pravastatin in metabolic syndrome for primary prevention of cardiovascular disease in Japan: a post hoc analysis of the MEGA study
    Teruhiko Matsushima
    Faculty of Human Life Science, Jissen Women s University, Tokyo, Japan
    J Cardiovasc Pharmacol Ther 17:153-8. 2012

Collaborators

Detail Information

Publications55

  1. ncbi request reprint Clinical characteristics of asthmatic patients prescribed various beta-agonist metered-dose inhalers at Yamagata University Hospital
    F Ojima
    Department of Pharmacy, Yamagata University Hospital, Yamagata 990-9585, Japan
    Yakugaku Zasshi 121:79-84. 2001
    ..Adequate instructions to individual patients who are prescribed a particular beta-agonist MDI should be provided by the medical staff, especially to outpatients, to reduce hospitalization and death from asthma...
  2. ncbi request reprint Histological changes of thyroid tissues in patients with liver cirrhosis
    R Gemma
    Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan
    Endocr J 48:535-42. 2001
    ..Perivascular fibrosis was more prominent in the cirrhosis group than in the controls. These findings suggest that thyroid glands in patients with liver cirrhosis have the characteristic features of hypoactivity...
  3. ncbi request reprint Management of severe subarachnoid hemorrhage; significance of assessment of both neurological and systemic insults at acute stage
    A Satoh
    Department of Neurosurgery, Saitama Medical School, Saitama, Japan
    Acta Neurochir Suppl 94:59-63. 2005
    ..For patients in G-well, SI over 50 means that there may be risks for systemic complications even in cases with good neurological condition...
  4. doi request reprint Effect of lipid-lowering therapy with atorvastatin on atherosclerotic aortic plaques: a 2-year follow-up by noninvasive MRI
    Atsushi Yonemura
    National Defense Medical College, Tokyo, Japan
    Eur J Cardiovasc Prev Rehabil 16:222-8. 2009
    ..However, association between serial plaque changes and LDL-cholesterol levels was not fully elucidated...
  5. ncbi request reprint Primary prevention of cardiovascular diseases among hypercholesterolemic Japanese with a low dose of pravastatin
    H Nakamura
    Mitsukoshi Health and Welfare Foundation, 1 24 1 Nishi shinjuku, Tokyo 160 0023, Japan
    Atheroscler Suppl 8:13-7. 2007
    ..Even though 68% of patients were women, who have been traditionally considered at less risk than men, significant CHD risk reduction was observed across all groups...
  6. ncbi request reprint Primary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): a prospective randomised controlled trial
    Haruo Nakamura
    Mitsukoshi Health and Welfare Foundation, Tokyo, Japan
    Lancet 368:1155-63. 2006
    ..Our aim was to assess whether evidence for treatment with statins derived from western populations can be extrapolated to the Japanese population...
  7. doi request reprint Pravastatin and cardiovascular risk in moderate chronic kidney disease
    Haruo Nakamura
    Mitsukoshi Health and Welfare Foundation, STEC Jyoho Building, 1 24 1 Nishishinjuku Shinjuku, Tokyo, 160 0023, Japan
    Atherosclerosis 206:512-7. 2009
    ....
  8. ncbi request reprint The relationship between the effect of pravastatin and risk factors for coronary heart disease in Japanese patients with hypercholesterolemia
    Toshitsugu Ishikawa
    Occupational Health Department, Sony Corporation, Tokyo, Japan
    Circ J 72:1576-82. 2008
    ..The present analysis determined the risk factors for CHD in the MEGA Study, a large primary prevention trial with pravastatin in Japanese with hypercholesterolemia...
  9. doi request reprint Low-dose pravastatin and age-related differences in risk factors for cardiovascular disease in hypercholesterolaemic Japanese: analysis of the management of elevated cholesterol in the primary prevention group of adult Japanese (MEGA study)
    Noriaki Nakaya
    Nakaya Clinic, Tokyo, Japan
    Drugs Aging 28:681-92. 2011
    ..Limited data are available regarding the relationship between age and the effect of HMG-CoA reductase inhibitor (statin) treatment...
  10. doi request reprint The effect of low-dose pravastatin in metabolic syndrome for primary prevention of cardiovascular disease in Japan: a post hoc analysis of the MEGA study
    Teruhiko Matsushima
    Faculty of Human Life Science, Jissen Women s University, Tokyo, Japan
    J Cardiovasc Pharmacol Ther 17:153-8. 2012
    ..These results indicate that low-dose pravastatin provides a substantial beneficial effect for the prevention of CVD in Japanese patients with MetSyn without known CVD, a population at proportionally high risk in primary prevention...
  11. ncbi request reprint Usefulness of LDL-C-related parameters to predict cardiovascular risk and effect of pravastatin in mild-to-moderate hypercholesterolemia
    Kyoichi Mizuno
    Department of Medicine, Nippon Medical School, Bunkyo ku, Tokyo, Japan
    J Atheroscler Thromb 19:176-85. 2012
    ....
  12. ncbi request reprint Associations between plasma C-reactive protein levels and the severities of coronary and aortic atherosclerosis
    Yukihiko Momiyama
    Division of Cardiology, National Hospital Organization Tokyo Medical Center, 2 5 1 Higashigaoka, Tokyo, Japan
    J Atheroscler Thromb 17:460-7. 2010
    ..Limited correlations between C-reactive protein (CRP) and coronary artery disease (CAD) have been reported. Recently, MRI became a useful tool for non-invasively evaluating atherosclerotic plaques in thoracic and abdominal aortas...
  13. ncbi request reprint Association between lowering low-density lipoprotein cholesterol with pravastatin and primary prevention of cardiovascular disease in mild to moderate hypercholesterolemic Japanese
    Tamio Teramoto
    Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan
    J Atheroscler Thromb 17:879-87. 2010
    ..To evaluate the relationship between low-density lipoprotein cholesterol (LDL-C) change and reduction of cardiovascular disease in the Management of Elevated cholesterol in the primary prevention Group of Adult Japanese (MEGA) study...
  14. ncbi request reprint Serum resistin levels and cardiovascular events in patients undergoing percutaneous coronary intervention
    Yukihiko Momiyama
    Department of Cardiology, National Hospital Organization Tokyo Medical Center, Meguro ku, Tokyo, Japan
    J Atheroscler Thromb 18:108-14. 2011
    ..Resistin is an adipocytokine that may link inflammation and atherosclerosis.We studied the associations of resistin levels with cardiovascular events and restenosis...
  15. ncbi request reprint Practical risk prediction tools for coronary heart disease in mild to moderate hypercholesterolemia in Japan: originated from the MEGA study data
    Tamio Teramoto
    Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan
    Circ J 72:1569-75. 2008
    ..A simple and practical risk prediction tool for coronary heart disease (CHD) to determine the specific risk level in each patient that fits the true clinical practice setting is needed and would be valuable in Japan...
  16. doi request reprint Usefulness of pravastatin in primary prevention of cardiovascular events in women: analysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA study)
    Kyoichi Mizuno
    Department of Internal Medicine, Nippon Medical School, 1 1 5, Sendagi, Bunkyo ku, Tokyo, 113 8603, Japan
    Circulation 117:494-502. 2008
    ..We conducted an exploratory analysis of the effect of diet plus pravastatin therapy on the primary prevention of cardiovascular events in women with data from a large-scale primary prevention trial with pravastatin...
  17. doi request reprint High plasma levels of matrix metalloproteinase-8 in patients with unstable angina
    Yukihiko Momiyama
    Division of Cardiology, National Hospital Organization Tokyo Medical Center, Meguro ku, Tokyo, Japan
    Atherosclerosis 209:206-10. 2010
    ..Thus, plasma MMP-8 levels were found to be high in patients with UAP, suggesting that MMP-8 levels in UAP may reflect coronary plaque instability and that MMP-8 is a promising biomarker for UAP...
  18. ncbi request reprint Effect of coffee intake on blood pressure in male habitual alcohol drinkers
    Kazuo Funatsu
    Mitsukoshi Health and Welfare Foundation, Tokyo, Japan
    Hypertens Res 28:521-7. 2005
    ..In conclusion, coffee intake of more than 3 cups per day in hypertensive and prehypertensive men who regularly consume alcohol lowers blood pressure...
  19. pmc Associations between headache and stress, alcohol drinking, exercise, sleep, and comorbid health conditions in a Japanese population
    Masako Yokoyama
    Mitsukoshi Health and Welfare Foundation, Shinjuku ku, Tokyo, Japan
    J Headache Pain 10:177-85. 2009
    ....
  20. ncbi request reprint Hangover susceptibility in relation to aldehyde dehydrogenase-2 genotype, alcohol flushing, and mean corpuscular volume in Japanese workers
    Masako Yokoyama
    Mitsukoshi Health and Welfare Foundation, Tokyo, Japan
    Alcohol Clin Exp Res 29:1165-71. 2005
    ..A biomarker for moderate-to-heavy drinking in persons with inactive aldehyde dehydrogenase-2 (ALDH2) is increased mean corpuscular volume (MCV)...
  21. ncbi request reprint Relationships between serum soluble leptin receptor level and serum leptin and adiponectin levels, insulin resistance index, lipid profile, and leptin receptor gene polymorphisms in the Japanese population
    Takeo Ogawa
    Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
    Metabolism 53:879-85. 2004
    ....
  22. ncbi request reprint Mean corpuscular volume and the aldehyde dehydrogenase-2 genotype in male Japanese workers
    Masako Yokoyama
    Mitsukoshi Health and Welfare Foundation, Tokyo, Japan
    Alcohol Clin Exp Res 27:1395-401. 2003
    ..Because moderate and heavy drinkers with ALDH2*1/2*2 have very high risks for esophageal cancer, MCV might serve as an indicator of these high-risk drinkers...
  23. ncbi request reprint Acute epiglottitis: a review of 80 patients
    H Nakamura
    Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyorin University, Tokyo, Japan
    J Laryngol Otol 115:31-4. 2001
    ..No sexual predominance was found, and there was no patient younger than 16 years of age. The patient fatality rate was 1.3 per cent, and the hospitalization period was markedly longer than those of other reports...
  24. ncbi request reprint Extracranial carotid plaque is increasing in Japanese ischemic stroke patients
    T Katsumata
    Internal Medicine, Division of Neurology, Nippon Medical School, Tokyo, Japan
    Acta Neurol Scand 116:20-5. 2007
    ..The objectives of this study were to investigate the prevalence of extracranial carotid plaque and the association between risk factors and carotid plaque in Japanese patients with ischemic stroke...
  25. ncbi request reprint Limitation of cigarette consumption by CYP2A6*4, *7 and *9 polymorphisms
    N Minematsu
    Division of Pulmonary Medicine, Dept of Medicine, Keio University, Tokyo, Japan
    Eur Respir J 27:289-92. 2006
    ..In conclusion, polymorphisms *4, *7 and *9 of CYP2A6 were detected in approximately three out of four Japanese smokers, and their daily cigarette consumption was genetically modulated by these functional polymorphisms...
  26. ncbi request reprint Serum pepsinogen can predict response to H2-receptor antagonist in patients with functional dyspepsia
    I Yoshikawa
    Third Department of Internal Medicine, University of Occupational and Environmental Health, Japan, School of Medicine, Kitakyushu, Japan
    Aliment Pharmacol Ther 16:1805-9. 2002
    ..Therapy for the relief of symptoms of functional dyspepsia is unpredictable...
  27. ncbi request reprint A trilogy of primary prevention statin trials. Panel discussion
    Y Matsuzawa
    Sumitomo Hospital, Osaka, Japan
    Atheroscler Suppl 8:19-24. 2007
    ..Japanese physicians tend to use small doses of statin and believe that these are effective in lowering cholesterol sufficiently with few side effects and encourage good compliance...
  28. ncbi request reprint Effect of coronary risk factors on arterial compensatory enlargement in japanese middle-aged patients with de novo single-vessel disease--an intravascular ultrasound study
    K Isoda
    First Department of Internal Medicine, National Defense Medical College, Saitama, Japan
    Clin Cardiol 24:443-50. 2001
    ..05). CONCLUSION: Hypertension and decreased HDL level may contribute to the shrinkage response in middle-aged patients with stable angina...
  29. ncbi request reprint Correction of hyperglycaemia reduces insulin resistance and serum soluble E-selectin levels in patients with Type 2 diabetes mellitus
    K Matsumoto
    Department of Internal Medicine, Sasebo Chuo Hospital, Sasebo, Nagasaki, Japan
    Diabet Med 18:224-8. 2001
    ..These changes might, in part, contribute to reduce the risk of diabetic microvascular and macrovascular complications in patients with Type 2 diabetes mellitus...
  30. ncbi request reprint Effects of soy protein on levels of remnant-like particles cholesterol and vitamin E in healthy men
    K Higashi
    First Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan
    J Nutr Sci Vitaminol (Tokyo) 47:283-8. 2001
    ..Therefore the supplementation of vitamin E may be required in subjects with long-term and abundant intake of soy protein...
  31. ncbi request reprint Analysis of genetic polymorphism in NQO1, GST-M1, GST-T1, and CYP3A4 in 469 Japanese patients with therapy-related leukemia/ myelodysplastic syndrome and de novo acute myeloid leukemia
    T Naoe
    Department of Infectious Diseases, The First Nagoya University School of Medicine, Japan
    Clin Cancer Res 6:4091-5. 2000
    ..The polymorphism of the 5' promoter region of CYP3A4 was not found in persons of Japanese ethnicity. These results suggest that the NQOJ polymorphism is significantly associated with the genetic risk of TRLIMDS...
  32. ncbi request reprint [Incidence of cerebral palsy in Himeji City 1983-1992]
    K Koterazawa
    Himeji City Center for the Handicapped, Hyogo
    No To Hattatsu 30:489-93. 1998
    ..5%) in 1983-87, and in 25 out of 51 (49.0%) in 1988-92. These results suggest that the increase in the incidence of CP mainly depends on changes of medical care for neonates...
  33. ncbi request reprint Characterization of N93S, I312T, and A333P missense mutations in two Japanese families with mitochondrial acetoacetyl-CoA thiolase deficiency
    T Fukao
    Department of Pediatrics, Gifu University School of Medicine, Japan
    Hum Mutat 12:245-54. 1998
    ..By contrast, Asn93 is located near the active site and may function to maintain a local loop structure. The mutation of Asn93 could directly disrupt disposition of the active site...
  34. ncbi request reprint [A study on the incidence of cerebral palsy among twins in Himeji City]
    K Koterazawa
    Himeji City Center for the Handicapped, Hyogo
    No To Hattatsu 30:20-3. 1998
    ..15%), and was particularly high in monozygotic twins. Since circulatory changes specific for twin pregnancies may cause brain damage, careful obstetric management is recommended for monozygotic twins...
  35. ncbi request reprint Association of a genetic variation in the beta 3-adrenergic receptor gene with coronary heart disease among Japanese
    K Higashi
    First Department of Internal Medicine, National Defense Medical College, Saitama, Japan
    Biochem Biophys Res Commun 232:728-30. 1997
    ..This mutation was associated with coronary heart disease and obesity but was not with glucose and lipid metabolism disorders in Japanese nationals...
  36. ncbi request reprint Japanese cases of type 1 thanatophoric dysplasia exclusively carry a C to T transition at nucleotide 742 of the fibroblast growth factor receptor 3 gene
    R K Pokharel
    Division of Genetics, International Center for Medical Research, Kobe University School of Medicine, Japan
    Biochem Biophys Res Commun 227:236-9. 1996
    ..No association was found between C742T and C882T, although both nucleotides changes were from CpG dinucleotide in a near location...
  37. ncbi request reprint [Epidemiology of neonatal brain damage]
    H Nakamura
    Department of Pediatrics, Kobe University School of Medicine
    No To Hattatsu 28:111-7. 1996
    ..And thus, the perinatal care will play an important role for the prevention of handicapped children...
  38. ncbi request reprint Serum creatinine level in predicting the development of hypertension. Ten-year follow-up of Japanese adults in a rural community
    K Miura
    Department of Public Health, Kanazawa Medical University, Ishikawa, Japan
    Am J Hypertens 7:390-5. 1994
    ..25 to 0.71). The mechanism of this association might relate to muscle mass and physical exercise or, possibly, to a primary renal abnormality. It appeared that the serum creatinine level may be useful in predicting future hypertension...
  39. ncbi request reprint Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors
    T Kusama
    Department of Tumor Biochemistry, Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan
    Cancer Res 61:4885-91. 2001
    ..These results suggest that HMG-CoA reductase inhibitors affect RhoA activation by preventing geranylgeranylation, which results in inhibition of EGF-induced invasiveness of human pancreatic cancer cells...
  40. ncbi request reprint Primary biliary cirrhosis among atomic bomb survivors in Nagasaki, Japan
    K Ohba
    Second Department of Internal Medicine, Nagasaki University School of Medicine, 1-7-1 Sakamoto, 852-8501, Nagasaki, Japan
    J Clin Epidemiol 54:845-50. 2001
    ....
  41. ncbi request reprint Epidermolysis bullosa simplex in Japanese and Korean patients: genetic studies in 19 cases
    K Yasukawa
    Department of Dermatology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita ku, Sapporo, 060 8638, Japan
    Br J Dermatol 155:313-7. 2006
    ..A recent report showed EBS cases in Israel had unique genetic features compared with European or U.S.A. associated families, which suggests that the ethnic and geographical features of EBS patients may be different...
  42. pmc An outbreak of gastroenteritis in Osaka, Japan due to Escherichia coli serogroup O166:H15 that had a coding gene for enteroaggregative E. coli heat-stable enterotoxin 1 (EAST1)
    Z Zhou
    Department of Health and Epidemiology, Osaka City Institute of Public Health and Environmental Sciences, Japan
    Epidemiol Infect 128:363-71. 2002
    ..We propose that diarrhoeal specimens should be examined for E. coli possessing the EAST1 gene...
  43. ncbi request reprint Utility and treatment decisions: 15 clinical cases in Japan
    N Matsuura
    Kobe University, School of Medicine, Chuo-ku, Kobe, Japan
    J Eval Clin Pract 7:419-30. 2001
    ..Patient autonomy must be strengthened by giving the patients realistic and unbiased information of the alternatives available and the possible outcomes...
  44. pmc Risk factors for age related maculopathy in a Japanese population: the Hisayama study
    M Miyazaki
    Department of Medical Information Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Br J Ophthalmol 87:469-72. 2003
    ..To examine the risk factors for age related maculopathy (ARM) in a sample Japanese population...
  45. ncbi request reprint Effects of transdermal and oral estrogen supplementation on endothelial function, inflammation and cellular redox state
    H Kawano
    Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto, Japan
    Int J Clin Pharmacol Ther 41:346-53. 2003
    ..These differentials in the effects caused by the course of administration may affect the future cardiovascular events...
  46. ncbi request reprint Incidence and prognosis of gastric cancer in a population-based cohort survey: the Hisayama study
    K Tanaka
    Dept of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Scand J Gastroenterol 39:459-63. 2004
    ....
  47. ncbi request reprint Listeria monocytogenes isolated from cold-smoked fish products in Osaka City, Japan
    H Nakamura
    Department of Food and Human Health Sciences, Graduate School of Human Life Science, Osaka City University, 3 3 138, Osaka 558 8585, Japan
    Int J Food Microbiol 94:323-8. 2004
    ..The finding suggest that persistent strains in each manufacturing facility proliferate during the summer and contaminate products during manufacturing processes...
  48. ncbi request reprint Remnant-like particles cholesterol is higher in diabetic patients with coronary artery disease
    K Higashi
    First Department of Internal Medicine, National Defense Medical College, Saitama, Japan
    Metabolism 50:1462-5. 2001
    ..001) and non-CAD with DM (P <.05). These results suggest that increased RLP-C to plasma-TG may be associated with CAD in middle-aged diabetic male subjects...
  49. ncbi request reprint Comparison of diagnostic methods for diabetes mellitus based on prevalence of retinopathy in a Japanese population: the Hisayama Study
    M Miyazaki
    Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Diabetologia 47:1411-5. 2004
    ....
  50. pmc Ten year recurrence after first ever stroke in a Japanese community: the Hisayama study
    J Hata
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3 1 1 Higashi ku, Fukuoka 812 8582, Japan
    J Neurol Neurosurg Psychiatry 76:368-72. 2005
    ..Very few population based cohort studies have focused on the long term recurrence of stroke...
  51. ncbi request reprint A case of gastrointestinal stromal tumour of the ampulla of Vater
    M Matsushita
    Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, 1 20 1 Handayama, Hamamatsu, Shizuoka 431 3192, Japan
    Dig Liver Dis 37:275-7. 2005
    ..Considering the recent advances in the diagnosis and treatment of gastrointestinal stromal tumour, this neoplasm should be included in the differential diagnosis of the tumours appearing in the duodenal ampulla region...
  52. ncbi request reprint Genetic polymorphism in matrix metalloproteinase-9 and pulmonary emphysema
    N Minematsu
    Cardiopulmonary Division, Department of Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku ku, Tokyo 160 8582, Japan
    Biochem Biophys Res Commun 289:116-9. 2001
    ..03) in subjects with C/T or T/T (n = 35) than in those with C/C (n = 75). These results suggest that the polymorphism of MMP-9 acts as a genetic factor for the development of smoking-induced pulmonary emphysema...
  53. ncbi request reprint Clinical significance of anti-citrullinated peptide antibody in Japanese patients with established rheumatoid arthritis
    H Nakamura
    Scand J Rheumatol 34:489-90. 2005
  54. ncbi request reprint Radiation streaming experiment through a labyrinth of the 12 GeV proton accelerator facility at KEK(2)--TLD REM-counter method
    H Nakamura
    High Energy Accelerator Research Organization KEK, 1 1 Oho, Tsukuba, Ibaraki 305 0801, Japan
    Radiat Prot Dosimetry 116:252-5. 2005
    ..The calculated doses using the Monte Carlo code, MCNPX basically agreed with the experimental results. However, unexpectedly, the calculated neutron doses were smaller than the measured ones along the upstream side of the labyrinth...
  55. ncbi request reprint [A retrospective study of hospitalized patients with fever of unknown origin (FUO) past six years]
    H Fukuhara
    First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus
    Kansenshogaku Zasshi 64:335-41. 1990
    ..The most common laboratory abnormality is an elevated erythrocyte sedimentation rate (89.6%). As the final diagnosis of FUO are changing with the development of diagnostic techniques, a new criteria of FUO is necessary...