Shigeko Torihashi

Summary

Affiliation: Nagoya University
Country: Japan

Publications

  1. doi request reprint The expression and crucial roles of BMP signaling in development of smooth muscle progenitor cells in the mouse embryonic gut
    Shigeko Torihashi
    Department of Health Science, Nagoya University Graduate School of Medicine, 1 1 20 Daikouminami, Higashi ku, Nagoya 461 8673, Japan
    Differentiation 77:277-89. 2009
  2. ncbi request reprint In vitro developmental model of the gastrointestinal tract from mouse embryonic stem cells
    Shigeko Torihashi
    Programs in Physical and Occupational Therapy, Nagoya University Graduate School of Medicine, 1 1 20 Daiko Minami, Higashi ku, Nagoya 461 8673, Japan
    Nagoya J Med Sci 69:133-7. 2007
  3. ncbi request reprint Gut-like structures from mouse embryonic stem cells as an in vitro model for gut organogenesis preserving developmental potential after transplantation
    Shigeko Torihashi
    Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Stem Cells 24:2618-26. 2006
  4. ncbi request reprint Crucial transcription factors in endoderm and embryonic gut development are expressed in gut-like structures from mouse ES cells
    Rie Matsuura
    Department of Anatomy and Molecular Cell Biology, Graduate School of Medicine, Nagoya University, Japan
    Stem Cells 24:624-30. 2006
  5. ncbi request reprint Formation of gut-like structures in vitro from mouse embryonic stem cells
    Shigeko Torihashi
    Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine, Japan
    Methods Mol Biol 330:279-85. 2006
  6. ncbi request reprint Spontaneous rhythmicity in cultured cell clusters isolated from mouse small intestine
    Shinsuke Nakayama
    Department of Cell Physiology, Nagoya University Graduate School of Medicine, Japan
    Jpn J Physiol 52:217-27. 2002
  7. ncbi request reprint Calcium oscillation linked to pacemaking of interstitial cells of Cajal: requirement of calcium influx and localization of TRP4 in caveolae
    Shigeko Torihashi
    Department of Anatomy, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    J Biol Chem 277:19191-7. 2002
  8. ncbi request reprint Attenuated nitrergic inhibitory neurotransmission to interstitial cells of Cajal in the lower esophageal sphincter with esophageal achalasia in children
    Yoshio Watanabe
    Department of Pediatric Surgery, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Pediatr Int 44:145-8. 2002
  9. doi request reprint Mesenchymal stem cells originating from ES cells show high telomerase activity and therapeutic benefits
    Nana Ninagawa
    Department of Health Sciences, Nagoya University Graduate School of Medicine, Higashi ku, Nagoya, Japan
    Differentiation 82:153-64. 2011
  10. doi request reprint Switching of actin isoforms in skeletal muscle differentiation using mouse ES cells
    Yota Mizuno
    Department of Physical Therapy, Nagoya University School of Health Sciences, Nagoya, Japan
    Histochem Cell Biol 132:669-72. 2009

Collaborators

Detail Information

Publications15

  1. doi request reprint The expression and crucial roles of BMP signaling in development of smooth muscle progenitor cells in the mouse embryonic gut
    Shigeko Torihashi
    Department of Health Science, Nagoya University Graduate School of Medicine, 1 1 20 Daikouminami, Higashi ku, Nagoya 461 8673, Japan
    Differentiation 77:277-89. 2009
    ..Taken together, BMP signaling was expressed for a short window in the smooth muscle progenitors and the signal, especially BMP2, plays an essential role in smooth muscle differentiation in cooperation with PDGF signaling...
  2. ncbi request reprint In vitro developmental model of the gastrointestinal tract from mouse embryonic stem cells
    Shigeko Torihashi
    Programs in Physical and Occupational Therapy, Nagoya University Graduate School of Medicine, 1 1 20 Daiko Minami, Higashi ku, Nagoya 461 8673, Japan
    Nagoya J Med Sci 69:133-7. 2007
    ..In addition, we pointed out several unique features different from gut in vivo that provide useful and advantageous tools to investigate the developmental mechanism of the gastrointestinal tract...
  3. ncbi request reprint Gut-like structures from mouse embryonic stem cells as an in vitro model for gut organogenesis preserving developmental potential after transplantation
    Shigeko Torihashi
    Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Stem Cells 24:2618-26. 2006
    ..They maintain their developmental potential after transplantation. Therefore, gut-like structures provide a unique and useful in vitro system for development and stem cell studies of the GI tract, including transplantation experiments...
  4. ncbi request reprint Crucial transcription factors in endoderm and embryonic gut development are expressed in gut-like structures from mouse ES cells
    Rie Matsuura
    Department of Anatomy and Molecular Cell Biology, Graduate School of Medicine, Nagoya University, Japan
    Stem Cells 24:624-30. 2006
    ..They also indicate that the in vitro system using mouse ES cells mimics in vivo development and should prove useful in the study of molecular mechanisms for endoderm and gut development...
  5. ncbi request reprint Formation of gut-like structures in vitro from mouse embryonic stem cells
    Shigeko Torihashi
    Department of Anatomy and Molecular Cell Biology, Nagoya University Graduate School of Medicine, Japan
    Methods Mol Biol 330:279-85. 2006
    ..EBs develop to form gut-like structures when induced to spontaneously enter a program of differentiation in vitro without addition of any extrinsic factors...
  6. ncbi request reprint Spontaneous rhythmicity in cultured cell clusters isolated from mouse small intestine
    Shinsuke Nakayama
    Department of Cell Physiology, Nagoya University Graduate School of Medicine, Japan
    Jpn J Physiol 52:217-27. 2002
    ....
  7. ncbi request reprint Calcium oscillation linked to pacemaking of interstitial cells of Cajal: requirement of calcium influx and localization of TRP4 in caveolae
    Shigeko Torihashi
    Department of Anatomy, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    J Biol Chem 277:19191-7. 2002
    ..Taken together, the results infer that the Ca(2+) oscillation in ICC is intimately linked to the pacemaker function and depends on Ca(2+) influx mediated by TRP4...
  8. ncbi request reprint Attenuated nitrergic inhibitory neurotransmission to interstitial cells of Cajal in the lower esophageal sphincter with esophageal achalasia in children
    Yoshio Watanabe
    Department of Pediatric Surgery, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Pediatr Int 44:145-8. 2002
    ..The aim of this investigation is to clarify the status of ICC and nitrergic inhibitory neurons in the LES of EA using immunohistochemistry...
  9. doi request reprint Mesenchymal stem cells originating from ES cells show high telomerase activity and therapeutic benefits
    Nana Ninagawa
    Department of Health Sciences, Nagoya University Graduate School of Medicine, Higashi ku, Nagoya, Japan
    Differentiation 82:153-64. 2011
    ..They thus indicate a promising new source of cell-based therapy without teratoma formation...
  10. doi request reprint Switching of actin isoforms in skeletal muscle differentiation using mouse ES cells
    Yota Mizuno
    Department of Physical Therapy, Nagoya University School of Health Sciences, Nagoya, Japan
    Histochem Cell Biol 132:669-72. 2009
    ..The exchange of isoforms is not directly linked to the sarcomere formation. As a result, ES cells provide a useful in vitro system for exploring skeletal muscle differentiation...
  11. ncbi request reprint Muscularis inflammation and the loss of interstitial cells of Cajal in the endothelin ETB receptor null rat
    Toshihiko Suzuki
    Department of Veterinary Pharmacology, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Tokyo 113 8657, Japan
    Am J Physiol Gastrointest Liver Physiol 287:G638-46. 2004
    ..Increased numbers and activation of macrophages may result in damage to ICC networks leading to disordered intestinal rhythmicity in regions of the gut in which myenteric ganglia are intact...
  12. ncbi request reprint [Genetic basis of autonomic gastrointestinal motility and pathophysiological models]
    Yoshiko Tokutomi
    Department of Pharmacology, Kumamoto University School of Medicine, Kumamoto 860 0811, Japan
    Nihon Yakurigaku Zasshi 119:227-34. 2002
    ..Here we review the genetic basis of autonomic gastrointestinal motility and the pathophysiological models...
  13. ncbi request reprint Phagocytotic activation of muscularis resident macrophages inhibits smooth muscle contraction in rat ileum
    Koichi Sato
    Laboratory of Veterinary Pharmacology, Faculty of Agriculture, Yamaguchi University, Japan
    J Vet Med Sci 69:1053-60. 2007
    ..These results indicate that phagocytotic activation of muscularis resident macrophages induces COX-2 gene expression and then results in production of PGE2 to suppress the smooth muscle contractile activity...
  14. ncbi request reprint In vitro functional gut-like organ formation from mouse embryonic stem cells
    Takatsugu Yamada
    Division of Developmental Biology, Department of Parasitology, Nara Medical University, Nara, Japan
    Stem Cells 20:41-9. 2002
    ..The aim of the present study was to investigate the electrophysiological and morphological properties of ES cell-derived contracting clusters...