Research Topics
| Masataka SawakiSummaryAffiliation: Nagoya University Country: Japan Publications
| Collaborators
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Detail Information
Publications
Phase I/II study of intraoperative radiotherapy for early breast cancer in JapanMasataka Sawaki
Department of Breast and Endocrine Surgery, Nagoya University School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
Breast Cancer 19:353-9. 2012..We have begun our study with the first step being a phase I-II study. This study was designed to identify the recommended dose and to test the feasibility of and tolerance to IORT in Japanese patients (UMIN000000918)...- Safety of adjuvant trastuzumab for HER-2-overexpressing elderly breast cancer patients: a multicenter cohort studyMasataka Sawaki
Department of Clinical Oncology and Chemotherapy, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
Breast Cancer 19:253-8. 2012..But there are few data on trastuzumab in elderly patients. We evaluated the incidence of adverse events among an elderly population of trastuzumab-treated HER-2-positive breast cancer patients in adjuvant settings... - A phase I study of intraoperative radiotherapy for early breast cancer in JapanMasataka Sawaki
Department of Breast and Endocrine Surgery, Nagoya University School of Medicine, 65 Tsurumai Cho, Showa ku 466 8550, Nagoya, Japan
World J Surg 33:2587-92. 2009..The present study was designed to identify the optimal intraoperative radiotherapy (IORT) dose for early breast cancer in Japanese women... 
High prevalence of HER-2/neu and p53 overexpression in inflammatory breast cancerMasataka Sawaki
Department of Medical Oncology, Cancer Institute Hospital and Cancer Chemotherapy Center, Japanese Foundation for Cancer Research
Breast Cancer 13:172-8. 2006..We have summarized a single-center experience involving IBC patients. Our objectives are to clarify molecular alterations of HER-2/neu and p53 in IBC and to investigate the prognostic factors...- The effect of toremifene on lipid metabolism compared with that of tamoxifen in vitroMasataka Sawaki
Department of Breast and Endocrine Surgery, Nagoya University School of Medicine, Nagoya, Japan
Gynecol Obstet Invest 71:213-6. 2011..TAM is known to increase intracellular triglyceride, but the action of TOR on lipid metabolism in vitro has not yet been determined. Aim: To compare the effect of TOR on lipid metabolism with that of TAM in vitro, using HepG2 cell lines... - Evaluation of trastuzumab without chemotherapy as a post-operative adjuvant therapy in HER2-positive elderly breast cancer patients: randomized controlled trial [RESPECT (N-SAS BC07)]Masataka Sawaki
Department of Clinical Oncology and Chemotherapy, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
Jpn J Clin Oncol 41:709-12. 2011.... - Efficacy and safety of trastuzumab as a single agent in heavily pretreated patients with HER-2/neu-overexpressing metastatic breast cancerMasataka Sawaki
Department of Medical Oncology, Cancer Institute Hospital and Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan
Tumori 90:40-3. 2004..It became available in Japan in June 2001. This study focuses on the efficacy and safety of trastuzumab as a single agent in second-third line treatment of HER2/neu-overexpressing metastatic breast cancer... - Efficacy and safety of combined trastuzumab and Paclitaxel therapy as a second-line treatment in women with metastatic breast cancer: a single institutional experienceKeiko Furukawa
Department of Medical Oncology, Cancer Institute Hospital, Tokyo, Japan
Breast Cancer 13:329-33. 2006..Trastuzumab is a humanized monoclonal antibody with specificity to the HER-2 protein. We evaluated the safety and efficacy of combined trastuzumab and paclitaxel therapy in women with metastatic breast cancer... - Patterns of lymph node metastases in papillary thyroid carcinoma: results from consecutive bilateral cervical lymph node dissectionHideki Takada
Department of Breast and Endocrine Surgery, Nagoya University Hospital, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
World J Surg 35:1560-6. 2011..The aim of this study was to clarify the LNM pattern in PTC patients based on our institution's experience with a consistent technique of bilateral neck dissection, and to consider the rational extent of lymph node dissection... - Prognostic importance of neuroendocrine differentiation in Japanese breast cancer patientsMasataka Sawaki
Department of Surgery II, Nagoya University School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
Surg Today 40:831-5. 2010..To evaluate the frequency and prognostic importance of neuroendocrine differentiation (NED) in Japanese breast cancer patients... - Phase II study of preoperative systemic treatment with the combination of docetaxel and trastuzumab in patients with locally advanced HER-2-overexpressing breast cancerMasataka Sawaki
Tokai Breast Cancer Clinical Research Group, Department of Breast and Endocrine Surgery, Nagoya University School of Medicine, Aichi, Japan
Breast 19:370-6. 2010..Subgroup analysis suggests that ER/PgR negative tumors might be associated with pathological response in locally advanced breast cancer... - Paclitaxel administered weekly in patients with docetaxel-resistant metastatic breast cancer: a single-center studyMasataka Sawaki
Department of Medical Oncology, Cancer Institute Hospital and Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan
Tumori 90:36-9. 2004..We evaluated retrospectively the efficacy and toxicity of paclitaxel in patients with docetaxel-resistant metastatic breast cancer... - Clinical usefulness of high-dose toremifene in patients relapsed on treatment with an aromatase inhibitorYutaka Yamamoto
Department of Breast and Endocrine Surgery, Kumamoto University, Japan
Breast Cancer 17:254-60. 2010..In this study, we investigated the efficacy and safety of toremifene (TOR, Fareston(®)), a selective estrogen receptor modulator (SERM)... - Phase I dose-escalating study of panobinostat (LBH589) administered intravenously to Japanese patients with advanced solid tumorsSachi Morita
Department of Clinical Oncology and Chemotherapy, Nagoya University Hospital, 65 Tsurumai Cho, Showa Ku, Nagoya, Aichi, 466 8560, Japan
Invest New Drugs 30:1950-7. 2012..Stable disease for ≥4 months was observed in six patients; however, there were no complete or partial responses. It is feasible to conclude that 20 mg/m(2) was the MTD and recommend as the starting dose for phase II clinical trials... - The feasibility study of docetaxel in patients with anaplastic thyroid cancerKenji Kawada
Department of Clinical Oncology and Chemotherapy, Nagoya University Hospital, Nagoya, Japan
Jpn J Clin Oncol 40:596-9. 2010..The median time to progression was 6 weeks (range, 1-50). Toxicity was tolerable. Docetaxel could be an effective drug for the treatment of anaplastic thyroid cancer, with tolerable toxicity... - Nodular fasciitis of the breastHironori Hayashi
Department of Breast and Endocrine Surgery, Nagoya University Hospital, Nagoya, Japan
Breast Cancer 14:337-9. 2007..Histologically, the excised tumor was consistent with nodular fasciitis of the breast. Nodular fasciitis should be considered in the differential diagnosis of a mass suspicious for breast cancer... - Anti-cancer effect of hyperthermia on breast cancer by magnetite nanoparticle-loaded anti-HER2 immunoliposomesToyone Kikumori
Department of Breast and Endocrine Surgery, Nagoya University Hospital, Showaku, Nagoya, Japan
Breast Cancer Res Treat 113:435-41. 2009..The effective targeting and cytocidal abilities of HML have been achieved using cell culture models. This study aimed to investigate feasibility of this modality for breast cancer treatment using tumor-bearing mouse models... - Extravasation of pegylated-liposomal doxorubicin: favorable outcome after immediate subcutaneous administration of corticosteroidsAyako Mitsuma
Department of Clinical Oncology and Chemotherapy, Nagoya University Hospital, Nagoya, Japan
Nagoya J Med Sci 74:189-92. 2012..There were no serious complications at the extravasation site, such as tissue necrosis or severe pain, and only a transient erythema of the skin and desquamation remained after 2 months... - Neuroendocrine tumor in the breastHiroshi Ogawa
Department of Radiology, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8560, Japan
Radiat Med 26:28-32. 2008..Both of the tumors were resected, and a primary breast neuroendocrine tumor (solid neuroendocrine carcinoma) and peritoneal dissemination of the ovarian carcinoid tumor were diagnosed... - Long term parathyroid function following total parathyroidectomy with autotransplantation in adult patients with MEN2AShigeru Yoshida
Department of Breast and Endocrine Surgery, Nagoya University Hospital, Nagoya, Aichi, Japan
Endocr J 56:545-51. 2009..Total parathyroidectomy with autotransplantation at the time of primary surgery for MTC, i.e. total thyroidectomy with bilateral central neck dissection, is a feasible approach for managing the risk of hyperparathyroidism... - Adrenal incidentaloma: review of 197 patients and report of a drug-related false-positive urinary normetanephrine resultTakahiro Ito
Department of Breast and Endocrine Surgery, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan
Surg Today 36:961-5. 2006..CONCLUSIONS: It is essential to diagnose the functional potential of adrenal incidentaloma preoperatively, and not to perform laparoscopic adrenalectomy for adrenal incidentaloma without careful evaluation first... - Comprehensive geriatric assessment in elderly breast cancer patientsNaruto Taira
Department of Breast and Endocrine Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Kita ku, Japan
Breast Cancer 17:183-9. 2010..A prospective investigation of the CGA as an outcome index in elderly breast cancer patients is required to address these issues...