Akiko Noda

Summary

Affiliation: Nagoya University
Country: Japan

Publications

  1. ncbi request reprint Discrimination of nonobstructive hypertrophic cardiomyopathy from hypertensive left ventricular hypertrophy on the basis of strain rate imaging by tissue Doppler ultrasonography
    Tomoko S Kato
    Department of Clinical Pathophysiology, Nagoya University, Graduate School of Medicine, Nagoya, Japan
    Circulation 110:3808-14. 2004
  2. ncbi request reprint Aortic pressure augmentation as a marker of cardiovascular risk in obstructive sleep apnea syndrome
    Akiko Noda
    Nagoya University School of Health Sciences, Higashi kuNagoya, Japan
    Hypertens Res 31:1109-14. 2008
  3. ncbi request reprint Continuous positive airway pressure improves daytime baroreflex sensitivity and nitric oxide production in patients with moderate to severe obstructive sleep apnea syndrome
    Akiko Noda
    Nagoya University School of Health Sciences, Nagoya, Japan
    Hypertens Res 30:669-76. 2007
  4. ncbi request reprint Beneficial effect of bilevel positive airway pressure on left ventricular function in ambulatory patients with idiopathic dilated cardiomyopathy and central sleep apnea-hypopnea: a preliminary study
    Akiko Noda
    Nagoya University School of Health Sciences, 1 1 20 Daiko, Minami, Nagoya, Aichi 461 8673, Japan
    Chest 131:1694-701. 2007
  5. doi request reprint Dobutamine stress testing as a diagnostic tool for evaluation of myocardial contractile reserve in asymptomatic or mildly symptomatic patients with dilated cardiomyopathy
    Masakazu Kobayashi
    Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    JACC Cardiovasc Imaging 1:718-26. 2008
  6. ncbi request reprint Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats
    Takashi Yamada
    Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Eur J Pharmacol 615:163-70. 2009
  7. ncbi request reprint Endomyocardial radial strain imaging and left ventricular relaxation abnormalities in patients with hypertrophic cardiomyopathy or hypertensive left ventricular hypertrophy
    Makoto Minoshima
    Department of Pathophysiology Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Circ J 73:2294-9. 2009
  8. ncbi request reprint Prognostic value of pacing-induced mechanical alternans in patients with mild-to-moderate idiopathic dilated cardiomyopathy in sinus rhythm
    Akihiro Hirashiki
    Department of Cardiovascular Genome Science, Nagoya University School of Medicine, Nagoya, Japan
    J Am Coll Cardiol 47:1382-9. 2006
  9. ncbi request reprint Beneficial effects of growth hormone-releasing peptide on myocardial oxidative stress and left ventricular dysfunction in dilated cardiomyopathic hamsters
    Yosuke Kato
    Pathophysiological Laboratory Sciences, Graduate School of Medicine, Nagoya University, Nagoya, Japan
    Circ J 74:163-70. 2010
  10. doi request reprint Continuous positive airway pressure intolerance associated with elevated nasal resistance is possible mechanism of complex sleep apnea syndrome
    Chie Nakazaki
    Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    Sleep Breath 16:747-52. 2012

Collaborators

Detail Information

Publications57

  1. ncbi request reprint Discrimination of nonobstructive hypertrophic cardiomyopathy from hypertensive left ventricular hypertrophy on the basis of strain rate imaging by tissue Doppler ultrasonography
    Tomoko S Kato
    Department of Clinical Pathophysiology, Nagoya University, Graduate School of Medicine, Nagoya, Japan
    Circulation 110:3808-14. 2004
    ..We investigated whether strain rate (SR) imaging derived from tissue Doppler imaging (TDI) is able to discriminate HCM from H-LVH...
  2. ncbi request reprint Aortic pressure augmentation as a marker of cardiovascular risk in obstructive sleep apnea syndrome
    Akiko Noda
    Nagoya University School of Health Sciences, Higashi kuNagoya, Japan
    Hypertens Res 31:1109-14. 2008
    ..109, r=0.530, p<0.001). OSAS may thus have an adverse effect on vascular function that can be ameliorated by appropriate treatment...
  3. ncbi request reprint Continuous positive airway pressure improves daytime baroreflex sensitivity and nitric oxide production in patients with moderate to severe obstructive sleep apnea syndrome
    Akiko Noda
    Nagoya University School of Health Sciences, Nagoya, Japan
    Hypertens Res 30:669-76. 2007
    ..CPAP may therefore reduce the risk of cardiovascular complications due to endothelial dysfunction or increased sympathetic activity...
  4. ncbi request reprint Beneficial effect of bilevel positive airway pressure on left ventricular function in ambulatory patients with idiopathic dilated cardiomyopathy and central sleep apnea-hypopnea: a preliminary study
    Akiko Noda
    Nagoya University School of Health Sciences, 1 1 20 Daiko, Minami, Nagoya, Aichi 461 8673, Japan
    Chest 131:1694-701. 2007
    ..We investigated whether treatment of central sleep apnea-hypopnea with bilevel positive airway pressure (BPAP) in ambulatory patients with idiopathic dilated cardiomyopathy (IDCM) might improve LV function...
  5. doi request reprint Dobutamine stress testing as a diagnostic tool for evaluation of myocardial contractile reserve in asymptomatic or mildly symptomatic patients with dilated cardiomyopathy
    Masakazu Kobayashi
    Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    JACC Cardiovasc Imaging 1:718-26. 2008
    ..We performed dobutamine stress testing for evaluation of myocardial contractile reserve in asymptomatic or mildly symptomatic patients with dilated cardiomyopathy (DCM)...
  6. ncbi request reprint Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats
    Takashi Yamada
    Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Eur J Pharmacol 615:163-70. 2009
    ..The overall protective action of nifedipine is likely attributable to its antioxidant effect as well as to its antihypertensive action...
  7. ncbi request reprint Endomyocardial radial strain imaging and left ventricular relaxation abnormalities in patients with hypertrophic cardiomyopathy or hypertensive left ventricular hypertrophy
    Makoto Minoshima
    Department of Pathophysiology Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Circ J 73:2294-9. 2009
    ..However, it is difficult to differentiate nonobstructive HCM from hypertensive LV hypertrophy (H-LVH)...
  8. ncbi request reprint Prognostic value of pacing-induced mechanical alternans in patients with mild-to-moderate idiopathic dilated cardiomyopathy in sinus rhythm
    Akihiro Hirashiki
    Department of Cardiovascular Genome Science, Nagoya University School of Medicine, Nagoya, Japan
    J Am Coll Cardiol 47:1382-9. 2006
    ..The myocardial expression of genes for Ca2+-handling proteins in such patients was also examined...
  9. ncbi request reprint Beneficial effects of growth hormone-releasing peptide on myocardial oxidative stress and left ventricular dysfunction in dilated cardiomyopathic hamsters
    Yosuke Kato
    Pathophysiological Laboratory Sciences, Graduate School of Medicine, Nagoya University, Nagoya, Japan
    Circ J 74:163-70. 2010
    ..The present study tested the hypothesis that the beneficial cardiac effects of GHRP might include attenuation of myocardial oxidative stress...
  10. doi request reprint Continuous positive airway pressure intolerance associated with elevated nasal resistance is possible mechanism of complex sleep apnea syndrome
    Chie Nakazaki
    Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    Sleep Breath 16:747-52. 2012
    ..However, the pathophysiology of CompSAS remains controversial...
  11. ncbi request reprint Effects of aged garlic extract on left ventricular diastolic function and fibrosis in a rat hypertension model
    Yuki Hara
    Department of Medical Technology, Nagoya University Graduate School of Medicine, 1 1 20 Daiko Minami, Higashi ku, Nagoya, Aichi 461 8673, Japan
    Exp Anim 62:305-10. 2013
    ..AGE significantly reduced LV interstitial fibrosis at 12 and 18 weeks of age. Chronic AGE intake attenuated LV diastolic dysfunction and fibrosis without significantly decreasing SBP in hypertensive DS rats. ..
  12. doi request reprint Pathogenetic role of increased nasal resistance in obese patients with obstructive sleep apnea syndrome
    Mitsuhiko Tagaya
    Department of Otorhinolaryngology, Graduate School of Medicine, Nagoya University, Nagoya, Aichi, Japan
    Am J Rhinol Allergy 24:51-4. 2010
    ..The role of increased nasal resistance in obstructive sleep apnea syndrome (OSAS) remains controversial. The aim of this study was to examine the pathogenetic role of nasal obstruction in obese patients with OSAS...
  13. ncbi request reprint Myocardial velocity gradient as a noninvasively determined index of left ventricular diastolic dysfunction in patients with hypertrophic cardiomyopathy
    Tomoko Kato
    Cardiovascular Division, Department of Clinical Pathophysiology, Nagoya University, Graduate School of Medicine, Nagoya, Japan
    J Am Coll Cardiol 42:278-85. 2003
    ..We investigated the utility of the peak negative myocardial velocity gradient (MVG) derived from tissue Doppler imaging (TDI) for evaluation of diastolic dysfunction in patients with hypertrophic cardiomyopathy (HCM)...
  14. doi request reprint Beneficial effects of torasemide on systolic wall stress and sympathetic nervous activity in asymptomatic or mildly symptomatic patients with heart failure: comparison with azosemide
    Ken Harada
    Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    J Cardiovasc Pharmacol 53:468-73. 2009
    ..The anti-aldosteronergic properties of torasemide may contribute to its favorable effects...
  15. doi request reprint Xanthine oxidase inhibition improves left ventricular dysfunction in dilated cardiomyopathic hamsters
    Keiko Hayashi
    Department of Pathophysiology Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan
    J Card Fail 14:238-44. 2008
    ..We tested whether xanthine oxidase (XO) inhibition could decrease myocardial oxidative stress and attenuate left ventricular (LV) remodeling and dysfunction in the TO-2 hamster model of dilated cardiomyopathy...
  16. doi request reprint Pioglitazone attenuates cardiac hypertrophy in rats with salt-sensitive hypertension: role of activation of AMP-activated protein kinase and inhibition of Akt
    Mayuko F Kato
    Department of Pathophysiology Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan
    J Hypertens 26:1669-76. 2008
    ..We investigated the effects of pioglitazone on cardiac hypertrophy and hypertrophic signaling in Dahl salt-sensitive hypertensive rats...
  17. ncbi request reprint Attenuation of ventricular hypertrophy and fibrosis in rats by pitavastatin: potential role of the RhoA-extracellular signal-regulated kinase-serum response factor signalling pathway
    Masako Saka
    Department of Cardiovascular Genome Science, Nagoya University School of Medicine, Nagoya, Japan
    Clin Exp Pharmacol Physiol 33:1164-71. 2006
    ....
  18. pmc Ca(2+) channel blocker benidipine promotes coronary angiogenesis and reduces both left-ventricular diastolic stiffness and mortality in hypertensive rats
    Takao Nishizawa
    Department of Cardiology, Nagoya University School of Medicine, Nagoya, Japan
    J Hypertens 28:1515-26. 2010
    ..We compared the effects of benidipine, which has beneficial cardiac effects, and nitrendipine, which does not, in an animal model of hypertensive diastolic heart failure (DHF)...
  19. doi request reprint Pharyngeal morphology: a determinant of successful nasal surgery for sleep apnea
    Mami Morinaga
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Laryngoscope 119:1011-6. 2009
    ..To estimate the effectiveness of nasal surgery on the occurrence of sleep apnea, and to analyze the pharyngeal morphology of apnea patients whose sleep-disordered breathing was ameliorated postoperatively...
  20. ncbi request reprint Impact of microarousal associated with increased negative esophageal pressure in sleep-disordered breathing
    Mayo Sukegawa
    Department of Medical Technology, Nagoya University School of Health Sciences, Higashi ku, Aichi, Japan
    Sleep Breath 13:369-73. 2009
    ..Microarousals" during sleep have not been analyzed systematically. We investigated the importance of "microarousals" (lasting 1.5-3 s)...
  21. doi request reprint Relation of 99mTc-sestamibi washout with myocardial properties in patients with hypertrophic cardiomyopathy
    Satoshi Isobe
    Department of Cardiology, Kami iida Dai ichi General Hospital, Kita ku, Nagoya, Japan
    J Nucl Cardiol 17:1082-90. 2010
    ..We sought to determine the relationship between (99m)Tc-sestamibi washout and myocardial properties in hypertrophic cardiomyopathy (HCM) patients...
  22. ncbi request reprint Relation of functional and morphological changes in mitochondria to myocardial contractile and relaxation reserves in asymptomatic to mildly symptomatic patients with hypertrophic cardiomyopathy
    Kazumasa Unno
    Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466 8550, Japan
    Eur Heart J 30:1853-62. 2009
    ..To examine the relation between mitochondrial dysfunction and myocardial contractile and relaxation reserves in hypertrophic cardiomyopathy (HCM)...
  23. ncbi request reprint Cardiac sympathetic dysfunction correlates with abnormal myocardial contractile reserve in dilated cardiomyopathy patients
    Satoru Ohshima
    Department of Cardiology, Nagoya University School of Medicine, Nagoya, Japan
    J Am Coll Cardiol 46:2061-8. 2005
    ..We investigated the relationship between iodine-123-metaiodobenzylguanidine (123I-MIBG) findings and myocardial contractile reserve in patients with mild to moderate dilated cardiomyopathy (DCM)...
  24. doi request reprint Effects of nasal surgery on sleep quality in obstructive sleep apnea syndrome with nasal obstruction
    Seiichi Nakata
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    Am J Rhinol 22:59-63. 2008
    ..A prospective study was performed in OSAS patients who underwent isolated nasal surgery in a tertiary referral center...
  25. doi request reprint Morphological examination of upper airway in obstructive sleep apnea
    Hidehito Yagi
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya, Aichi 466 8550, Japan
    Auris Nasus Larynx 36:444-9. 2009
    ..An aim of this study was to assess the predictive power of an otorhinolaryngological examination of the upper airway to identify risk factors of obstructive sleep apnea syndrome (OSAS) in the patients...
  26. doi request reprint Monitoring sleep-wake rhythm with actigraphy in patients on continuous positive airway pressure therapy
    Masafumi Otake
    Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Respiration 82:136-41. 2011
    ..However, residual excessive sleepiness is observed in some patients even though CPAP therapy eliminates sleep apnea and desaturation...
  27. ncbi request reprint Differential myolysis of myocardium and skeletal muscle in hamsters with dilated cardiomyopathy: beneficial protective effect of diltiazem
    Yosuke Kato
    Pathophysiological Laboratory Sciences, Graduate School of Medicine, Nagoya University, Nagoya, Japan
    Circ J 70:1497-502. 2006
    ....
  28. ncbi request reprint Effect of nicorandil on left ventricular end-diastolic pressure during exercise in patients with hypertrophic cardiomyopathy
    Hideo Izawa
    Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Eur Heart J 24:1340-8. 2003
    ..The effects of nicorandil on left ventricular end-diastolic pressure during exercise were examined in patients with this condition...
  29. doi request reprint Association of insomnia and short sleep duration with atherosclerosis risk in the elderly
    Chie Nakazaki
    Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Am J Hypertens 25:1149-55. 2012
    ..Short sleep duration is associated with an increased risk of cardiovascular disease and all-cause mortality, although a relationship with atherosclerosis in the elderly remains unclear...
  30. ncbi request reprint Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and failure in low-aldosterone hypertensive rats
    Kohzo Nagata
    Department of Medical Technology, Nagoya University School of Health Sciences, Nagoya, Japan
    Hypertension 47:656-64. 2006
    ..The beneficial cardiac effects of eplerenone are likely attributable, at least in part, to attenuation of myocardial oxidative stress and coronary vascular inflammation induced by glucocorticoid-activated MRs...
  31. ncbi request reprint Factors contributing to sleep disturbance and hypnotic drug use in hemodialysis patients
    Akiko Noda
    Nagoya University School of Health Sciences, 1 1 20 Daiko, Minami, Higashi ku, Nagoya, Aichi 461 8673, Japan
    Intern Med 45:1273-8. 2006
    ..Sleep disturbance and the use of hypnotic medications are common in patients on hemodialysis. Factors that contribute to sleep disturbance and the use of hypnotic medications in hemodialysis patients were investigated...
  32. doi request reprint Effects of sedative antidepressants on prefrontal cortex activity during verbal fluency task in healthy subjects: a near-infrared spectroscopy study
    Kunihiro Kohmura
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa, Nagoya, Aichi, Japan
    Psychopharmacology (Berl) 226:75-81. 2013
    ..However, the influence of psychotropic drugs on NIRS measurements has not been clarified...
  33. ncbi request reprint Comparison of sleep-disordered breathing and heart rate variability between hemodialysis and non-hemodialysis days in hemodialysis patients
    Mayo Sukegawa
    Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 70:83-8. 2008
    ..The simultaneous analysis of HRV reflecting autonomic activity and sleep-disordered breathing on both hemodialysis and non-hemodialysis days provides important information...
  34. ncbi request reprint Influence of nasal resistance on initial acceptance of continuous positive airway pressure in treatment for obstructive sleep apnea syndrome
    Tatsuki Sugiura
    Department of In Home Medicine, Nagoya University Hospital, Nagoya, Japan
    Respiration 74:56-60. 2007
    ..Continuous positive airway pressure (CPAP) is considered as the standard therapy for obstructive sleep apnea syndrome (OSAS), but some patients with OSAS are unable to accept CPAP due to nasal obstruction and poor nasal airflow...
  35. doi request reprint The effects of acute treatment with tandospirone, diazepam, and placebo on driving performance and cognitive function in healthy volunteers
    Masahiro Takahashi
    Department of Psychiatry, Graduate School of Medicine, Nagoya University, Nagoya, Aichi, Japan
    Hum Psychopharmacol 25:260-7. 2010
    ..To assess the effects of two anxiolytics, diazepam and tandospirone, on driving performance from methodological viewpoints taking frequent rear-end collisions into account...
  36. ncbi request reprint Sex differences in the relationships between electrocardiographic abnormalities and the extent of left ventricular hypertrophy by echocardiography
    Hikari Ochi
    Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Ann Noninvasive Electrocardiol 11:222-9. 2006
    ..Furthermore, the diagnostic accuracy of abnormalities in ST-T patterns for LVH is known to be uncertain, especially in women. We examined the relationship between electrocardiographic abnormalities and the extent of LVH...
  37. ncbi request reprint Reduced nasal resistance after simple tonsillectomy in patients with obstructive sleep apnea
    Seiichi Nakata
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    Am J Rhinol 21:192-5. 2007
    ..The aim of this study was to investigate the effects of simple tonsillectomy on nasal resistance in patients with obstructive sleep apnea syndrome (OSAS)...
  38. ncbi request reprint Nasal resistance for determinant factor of nasal surgery in CPAP failure patients with obstructive sleep apnea syndrome
    Seiichi Nakata
    Department of Otorhinolaryngology, Nagoya University School of Medicine, Nagoya, Japan
    Rhinology 43:296-9. 2005
    ....
  39. ncbi request reprint REM sleep is impaired by a small amount of alcohol in young women sensitive to alcohol
    Seiko Miyata
    Department of Pathophysiological Laboratory Sciences Nagoya University Graduate School of Medicine, 1 1 20 Daiko Minami, Higashi, Nagoya, Aichi 461 8673
    Intern Med 43:679-84. 2004
    ..The effect of a small amount of alcohol on the sleep structure in relation to alcohol sensitivity was examined using polysomnography (PSG)...
  40. ncbi request reprint The role of malocclusion in non-obese patients with obstructive sleep apnea syndrome
    Etsuko Miyao
    Ars Orthodontics Clinic, Nagoya University School of Health Sciences, Nagoya
    Intern Med 47:1573-8. 2008
    ..Malocclusion influences the occurrence of sleep apnea, but the pathology of malocclusion in OSAS has not yet been fully investigated. Therefore, we investigated malocclusion in patients with OSAS using cephalometric and dental analysis...
  41. ncbi request reprint Biphasic relaxation-frequency relations in patients with effort angina pectoris: a new marker of myocardial demand ischemia
    Hisashi Umeda
    Department of Organ Regulation and Internal Medicine, Nagoya University, Graduate School of Medicine, Nagoya, Japan
    Am Heart J 146:75-83. 2003
    ..Relaxation-frequency relations (RFR) during demand ischemia have not been fully examined in patients with effort angina pectoris (AP). We sought to clarify the effects of pacing and exercise on RFR in patients with AP...
  42. doi request reprint Insufficient sleep impairs driving performance and cognitive function
    Seiko Miyata
    Nagoya University, School of Health Sciences, 1 1 20 Daiko minami Higashi ku, Nagoya, Aichi 461 8673, Japan
    Neurosci Lett 469:229-33. 2010
    ..One night of insufficient sleep affects daytime cognitive function and driving performance and this was accompanied by the changes of cortical oxygenation response...
  43. ncbi request reprint Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure
    Xian Wu Cheng
    Department of Cardiovascular Genome Science, Nagoya University School of Medicine, 65 Tsuruma cho, Showa Ku, Nagoya 466 8550, Japan
    Hypertension 48:979-87. 2006
    ..These results suggest that cathepsin S participates in pathological LV remodeling associated with hypertension-induced HF. This protease is, thus, a potential target for therapeutics aimed at preventing or reversing cardiac remodeling...
  44. ncbi request reprint Obstructive sleep apnoea associated with congenital choanal atresia
    Seiichi Nakata
    Department of Otorhinolaryngology, Nagoya University School of Medicine, Aichi, Japan
    J Laryngol Otol 119:209-11. 2005
    ..On the basis of these observations, we modified the diagnosis to obstructive sleep apnoea syndrome (OSAS) secondary to congenital choanal atresia...
  45. ncbi request reprint Mineralocorticoid receptor antagonism ameliorates left ventricular diastolic dysfunction and myocardial fibrosis in mildly symptomatic patients with idiopathic dilated cardiomyopathy: a pilot study
    Hideo Izawa
    Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Circulation 112:2940-5. 2005
    ....
  46. ncbi request reprint Daytime polysomnography for early diagnosis and treatment of patients with suspected sleep-disordered breathing
    Seiko Miyata
    Department of Pathophysiological Laboratory Sciences, Nagoya University, Graduate School of Medicine, 1 1 20 Daiko Minami, Nagoya shi, 61 8673 Aichi, Japan
    Sleep Breath 11:109-15. 2007
    ..Although dPSG has limitations, these results indicate that dPSG recording is clinically useful for the diagnosis of and determination of types of treatment in patients with suspected SDB...
  47. ncbi request reprint Follow-up for patients with obstructive sleep apnea syndrome using a portable recording device
    Seiko Miyata
    Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Japan
    Nagoya J Med Sci 69:37-43. 2007
    ..It may prove to be a useful tool for following up patients...
  48. ncbi request reprint Differential cardiovascular effects of endotoxin derived from Escherichia coli or Pseudomonas aeruginosa
    Aya Matsushita
    Pathophysiological Laboratory Sciences, Graduate School of Medicine, Nagoya University, Japan
    Exp Anim 56:339-48. 2007
    ..These differential responses may be attributable in part to the difference in the associated increases in the plasma concentration of TNF-alpha. The cardiovascular effects of LPS thus depend on the causative organisms...
  49. ncbi request reprint Assessment of continuous positive airway pressure treatment in obstructive sleep apnea syndrome using 24-hour urinary catecholamines
    Mayo Sukegawa
    The Department of Pathophysiological Laboratory Sciences, Nagoya University, Graduate School of Medicine, Japan
    Clin Cardiol 28:519-22. 2005
    ..Obstructive sleep apnea syndrome (OSAS) is related to diurnal sympathetic hyperactivity and increased blood pressure, both factors that are likely to lead to the development of cardiovascular disease...
  50. ncbi request reprint Nicorandil promotes myocardial capillary and arteriolar growth in the failing heart of Dahl salt-sensitive hypertensive rats
    Jinglan Xu
    Department of Cardiovascular Genome Science, Nagoya University School of Medicine, Nagoya 466 8550, Japan
    Hypertension 46:719-24. 2005
    ..Nicorandil may prove beneficial for the treatment of hypertensive heart failure as well as of ischemic heart disease...
  51. ncbi request reprint Glucose intolerance, as reflected by hemoglobin A1c level, is associated with the incidence and severity of transplant coronary artery disease
    Tomoko Kato
    Department of Cardiology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    J Am Coll Cardiol 43:1034-41. 2004
    ..The possible effect of plasma hemoglobin A(1c) (HbA(1c)) on the development of transplant coronary artery disease (TxCAD) was investigated...
  52. ncbi request reprint Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure
    Sahoko Ichihara
    Department of Cardiovascular Genome Science, Nagoya University School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Cardiovasc Res 69:726-35. 2006
    ..We have now investigated the role of MMPs and their tissue inhibitors (TIMPs) in the transition from compensated left ventricular (LV) hypertrophy to heart failure as well as the effects of pravastatin on this transition in a rat model...
  53. ncbi request reprint Pitavastatin improves cardiac function and survival in association with suppression of the myocardial endothelin system in a rat model of hypertensive heart failure
    Masako Saka
    Department of Cardiovascular Genome Science, Nagoya University School of Medicine, Japan
    J Cardiovasc Pharmacol 47:770-9. 2006
    ..Both early and late pitavastatin treatment thus improved cardiac function and survival, with modulation of extracellular matrix remodeling and endothelin-1 signaling possibly contributing to these beneficial effects...
  54. ncbi request reprint Attenuation of cardiac dysfunction by a PPAR-alpha agonist is associated with down-regulation of redox-regulated transcription factors
    Sahoko Ichihara
    Department of Cardiovascular Genome Science, Nagoya University School of Medicine, Japan
    J Mol Cell Cardiol 41:318-29. 2006
    ..These effects were associated with inhibition of the inflammatory response and of activation of redox-regulated transcription factors in the left ventricle...
  55. ncbi request reprint Progressive development of pulmonary hypertension leading to right ventricular hypertrophy assessed by echocardiography in rats
    Yosuke Kato
    School of Health Sciences, Nagoya University, 1 1 20 Daiko Minami, Higashi ku, Nagoya 461 8673, Japan
    Exp Anim 52:285-94. 2003
    ..In conclusion, the progressive development of pulmonary hypertension leading to RV hypertrophy can be evaluated appropriately by echocardiography including PA flow Doppler indices in rats...
  56. ncbi request reprint Comparison of accelerometry and oxymetry for measuring daily physical activity
    Yumiko Yokoyama
    First Department of Internal Medicine, Nagoya University School of Medicine, Japan
    Circ J 66:751-4. 2002
    ..Accelerometry is a reasonably accurate and feasible method for evaluating the physical activities of non-athletes, and could be a common tool for epidemiological research and health promotion despite its limitations...
  57. ncbi request reprint Clinical protocol for angiogenesis by intramyocardial injection of autologous bone marrow mononuclear cells in patients with severe coronary artery disease: TACT-NAGOYA-HEART
    Hideo Izawa
    Department of Cardiology, Nagoya University Graduate School of Medicine, Japan
    Circ J 70:1180-3. 2006
    ..Intramyocardial injection of autologous bone marrow mononuclear cells (ABMMCs) has been shown to induce neovascularization of ischemic myocardium...